EA200000584A2 - Твердые фармацевтические композиции с контролируемым высвобождением, получаемые тепловым формованием - Google Patents
Твердые фармацевтические композиции с контролируемым высвобождением, получаемые тепловым формованиемInfo
- Publication number
- EA200000584A2 EA200000584A2 EA200000584A EA200000584A EA200000584A2 EA 200000584 A2 EA200000584 A2 EA 200000584A2 EA 200000584 A EA200000584 A EA 200000584A EA 200000584 A EA200000584 A EA 200000584A EA 200000584 A2 EA200000584 A2 EA 200000584A2
- Authority
- EA
- Eurasian Patent Office
- Prior art keywords
- release pharmaceutical
- controlled
- pharmaceutical composition
- thermoformable
- solid
- Prior art date
Links
- 238000013270 controlled release Methods 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 239000007787 solid Substances 0.000 title abstract 2
- 239000004480 active ingredient Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229920000642 polymer Polymers 0.000 abstract 1
- 229920000193 polymethacrylate Polymers 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/745—Polymers of hydrocarbons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Abstract
(57) Данное изобретение относится к новым твердым фармацевтическим композициям с контролируемым высвобождением, полученным тепловым формованием в горячем состоянии смеси, основанной на полимерах, принадлежащих к семейству полиметакрилатов, и медицинском активном ингредиенте (ингредиентах).
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9908210A FR2795326B1 (fr) | 1999-06-28 | 1999-06-28 | Composition pharmaceutique solide thermoformable a liberation controlee |
Publications (3)
Publication Number | Publication Date |
---|---|
EA200000584A2 true EA200000584A2 (ru) | 2000-12-25 |
EA200000584A3 EA200000584A3 (ru) | 2001-04-23 |
EA003751B1 EA003751B1 (ru) | 2003-08-28 |
Family
ID=9547360
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EA200000584A EA003751B1 (ru) | 1999-06-28 | 2000-06-27 | Твердые фармацевтические композиции с контролируемым высвобождением, получаемые тепловым формованием |
Country Status (23)
Country | Link |
---|---|
US (1) | US6319520B1 (ru) |
EP (1) | EP1064935B2 (ru) |
JP (2) | JP2001031591A (ru) |
KR (1) | KR100554899B1 (ru) |
CN (1) | CN1174744C (ru) |
AT (1) | ATE395045T1 (ru) |
AU (1) | AU765885B2 (ru) |
BR (1) | BR0002880A (ru) |
CA (1) | CA2312545C (ru) |
CY (1) | CY1110351T1 (ru) |
DE (1) | DE60038848D1 (ru) |
DK (1) | DK1064935T4 (ru) |
EA (1) | EA003751B1 (ru) |
ES (1) | ES2307489T5 (ru) |
FR (1) | FR2795326B1 (ru) |
HK (1) | HK1033435A1 (ru) |
HU (1) | HU229342B1 (ru) |
NO (1) | NO331449B1 (ru) |
NZ (1) | NZ505431A (ru) |
PL (1) | PL202494B1 (ru) |
PT (1) | PT1064935E (ru) |
SI (1) | SI1064935T2 (ru) |
ZA (1) | ZA200003245B (ru) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ510311A (en) * | 1998-09-08 | 2003-08-29 | Smithkline Beecham Corp | Lipstatin derivative - soluble fiber tablets |
FR2795326B1 (fr) * | 1999-06-28 | 2001-08-31 | Adir | Composition pharmaceutique solide thermoformable a liberation controlee |
DE10026698A1 (de) | 2000-05-30 | 2001-12-06 | Basf Ag | Selbstemulgierende Wirkstoffformulierung und Verwendung dieser Formulierung |
FR2818550B1 (fr) * | 2000-12-26 | 2003-02-07 | Servier Lab | Composition pharmaceutique solide thermoformable pour la liberation controle de perindopril |
FR2818552B1 (fr) * | 2000-12-26 | 2003-02-07 | Servier Lab | Compositions pharmaceutique solide thermoformable pour la liberation controlee d'ivabradine |
US6764505B1 (en) | 2001-04-12 | 2004-07-20 | Advanced Cardiovascular Systems, Inc. | Variable surface area stent |
US7862495B2 (en) | 2001-05-31 | 2011-01-04 | Advanced Cardiovascular Systems, Inc. | Radiation or drug delivery source with activity gradient to minimize edge effects |
US7247313B2 (en) * | 2001-06-27 | 2007-07-24 | Advanced Cardiovascular Systems, Inc. | Polyacrylates coatings for implantable medical devices |
US7175873B1 (en) | 2001-06-27 | 2007-02-13 | Advanced Cardiovascular Systems, Inc. | Rate limiting barriers for implantable devices and methods for fabrication thereof |
US6656216B1 (en) | 2001-06-29 | 2003-12-02 | Advanced Cardiovascular Systems, Inc. | Composite stent with regioselective material |
GB0117619D0 (en) * | 2001-07-19 | 2001-09-12 | Phoqus Ltd | Pharmaceutical dosage form |
US20030204180A1 (en) * | 2002-04-30 | 2003-10-30 | Kimberly-Clark Worldwide, Inc. | Temperature responsive delivery systems |
US7622146B2 (en) * | 2002-07-18 | 2009-11-24 | Advanced Cardiovascular Systems, Inc. | Rate limiting barriers for implantable devices and methods for fabrication thereof |
US7169178B1 (en) | 2002-11-12 | 2007-01-30 | Advanced Cardiovascular Systems, Inc. | Stent with drug coating |
MXPA05011071A (es) | 2003-04-21 | 2005-12-12 | Euro Celtique Sa | Forma de dosificacion resistente a la alteracion que comprende particulas co-extrusionadas de agente adverso y proceso de fabricacion de las misma. |
TWI357815B (en) * | 2003-06-27 | 2012-02-11 | Euro Celtique Sa | Multiparticulates |
US20060165790A1 (en) * | 2003-06-27 | 2006-07-27 | Malcolm Walden | Multiparticulates |
CA2524300C (en) | 2003-08-08 | 2008-10-28 | Biovail Laboratories International Srl | Modified-release tablet of bupropion hydrochloride |
US8377952B2 (en) | 2003-08-28 | 2013-02-19 | Abbott Laboratories | Solid pharmaceutical dosage formulation |
US8025899B2 (en) | 2003-08-28 | 2011-09-27 | Abbott Laboratories | Solid pharmaceutical dosage form |
US7198675B2 (en) | 2003-09-30 | 2007-04-03 | Advanced Cardiovascular Systems | Stent mandrel fixture and method for selectively coating surfaces of a stent |
CN1938004B (zh) | 2004-03-30 | 2011-12-21 | 欧洲凯尔特公司 | 包含吸附剂和不利剂的抗篡改剂型 |
AU2005259961B2 (en) * | 2004-06-25 | 2012-05-17 | Board Of Regents, The University Of Texas System | Methods and compositions for the treatment of attention deficit hyperactivity disorder and hyperphenylalanemia |
GB2418854B (en) | 2004-08-31 | 2009-12-23 | Euro Celtique Sa | Multiparticulates |
US7867547B2 (en) | 2005-12-19 | 2011-01-11 | Advanced Cardiovascular Systems, Inc. | Selectively coating luminal surfaces of stents |
ES2427724T3 (es) * | 2006-02-03 | 2013-10-31 | Evonik Röhm Gmbh | Composiciones farmacéuticas, que contienen mezclas de polímeros y de sustancias activas difícilmente solubles en agua |
CA2646593C (en) * | 2006-03-20 | 2015-12-08 | Duramed Pharmaceuticals, Inc. | Flexible, compressed intravaginal rings, methods of making and using the same, and apparatus for making the same |
US8069814B2 (en) | 2006-05-04 | 2011-12-06 | Advanced Cardiovascular Systems, Inc. | Stent support devices |
US8603530B2 (en) | 2006-06-14 | 2013-12-10 | Abbott Cardiovascular Systems Inc. | Nanoshell therapy |
US8048448B2 (en) | 2006-06-15 | 2011-11-01 | Abbott Cardiovascular Systems Inc. | Nanoshells for drug delivery |
US8017237B2 (en) | 2006-06-23 | 2011-09-13 | Abbott Cardiovascular Systems, Inc. | Nanoshells on polymers |
DE102007009242A1 (de) * | 2007-02-22 | 2008-09-18 | Evonik Röhm Gmbh | Pellets mit magensaftresistenter Wirkstoff-Matix |
JP4642134B2 (ja) * | 2007-05-01 | 2011-03-02 | コンサート ファーマシューティカルズ インコーポレイテッド | ナフチル(エチル)アセトアミド |
US8048441B2 (en) | 2007-06-25 | 2011-11-01 | Abbott Cardiovascular Systems, Inc. | Nanobead releasing medical devices |
WO2010099508A1 (en) | 2009-02-26 | 2010-09-02 | Theraquest Biosciences, Inc. | Extended release oral pharmaceutical compositions of 3-hydroxy-n-methylmorphinan and method of use |
CN101481321B (zh) * | 2009-02-27 | 2012-04-18 | 上海医药工业研究院 | 阿戈美拉汀卤化氢复合物及其制备方法 |
WO2012130837A1 (en) | 2011-03-28 | 2012-10-04 | Ratiopharm Gmbh | Solid agomelatine in non-crystalline form |
EP2550863A1 (de) * | 2011-07-27 | 2013-01-30 | Bayer Intellectual Property GmbH | Aktivstoffhaltige Partikel auf Polyacrylat-Basis |
EA201490500A1 (ru) * | 2011-08-30 | 2014-06-30 | Университейт Гент | Многослойный высвобождающий состав |
CA2877410A1 (en) | 2012-07-16 | 2014-01-23 | Ratiopharm Gmbh | Complex of agomelatine and cyclodextrin |
JO3339B1 (ar) * | 2012-09-11 | 2019-03-13 | Shanghai Inst Pharmaceutical Ind | شكل مستقر غير متبلور من الأغوميلاتين وعملية تحضيره والتركيبات الدوائية التي تحتوي عليه |
KR101659983B1 (ko) | 2012-12-31 | 2016-09-26 | 주식회사 삼양바이오팜 | 용융 압출된 방출 제어용 약학 조성물, 및 이를 포함하는 경구용 제제 |
EP2810647A1 (en) | 2013-06-06 | 2014-12-10 | Zentiva, a.s. | Pharmaceutical formulations comprising agomelatine in the form of agomelatine co-crystal with an organic acid |
EP2810656B1 (en) | 2013-06-06 | 2017-08-02 | Zentiva, a.s. | Agomelatine formulations comprising agomelatine in the form of co-crystals |
CN103724415B (zh) * | 2013-12-31 | 2015-05-27 | 中山大学 | 斜带石斑鱼性别调控基因Rspo1及其制备方法和应用 |
PT109154B (pt) * | 2016-02-12 | 2019-11-05 | Univ De Coimbra | Tecnologia não-invasiva de inserto ocular para libertação controlada de fármacos |
FR3070619A1 (fr) * | 2017-09-01 | 2019-03-08 | Ab7 Innovation | Piece moulee monolithique en matrice multiple pour la diffusion d’actifs et son procede d’obtention |
EP3459527B1 (en) | 2017-09-20 | 2022-11-23 | Tillotts Pharma Ag | Method for preparing a solid dosage form comprising antibodies by wet granulation, extrusion and spheronization |
KR20200083500A (ko) * | 2017-11-02 | 2020-07-08 | 이시하라 산교 가부시끼가이샤 | 서방성 의약 조성물 |
KR101856911B1 (ko) * | 2017-12-13 | 2018-05-10 | 동국대학교 산학협력단 | 펠루비프로펜의 서방성 고체분산체 제제 및 이의 제조방법 |
CN109985025B (zh) * | 2017-12-29 | 2023-01-13 | 沈阳药科大学 | 具有pH触发释药特征的眼部缓释给药系统 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5102668A (en) * | 1990-10-05 | 1992-04-07 | Kingaform Technology, Inc. | Sustained release pharmaceutical preparation using diffusion barriers whose permeabilities change in response to changing pH |
DE4138513A1 (de) † | 1991-11-23 | 1993-05-27 | Basf Ag | Feste pharmazeutische retardform |
CA2075517C (en) * | 1992-04-01 | 1997-03-11 | John Wick | Transdermal patch incorporating a polymer film incorporated with an active agent |
US5965161A (en) * | 1994-11-04 | 1999-10-12 | Euro-Celtique, S.A. | Extruded multi-particulates |
JPH11514979A (ja) † | 1995-09-07 | 1999-12-21 | フイズ テクノロジーズ リミテッド | 実質的に非溶解性の生体作用薬剤をバイオ・アベイラブルにするシステム |
DE19539362A1 (de) † | 1995-10-23 | 1997-04-24 | Basf Ag | Verfahren zur Herstellung von festen Arzneiformen |
DE19728516C2 (de) * | 1997-07-04 | 1999-11-11 | Sanol Arznei Schwarz Gmbh | TTS zur Verabreichung von Levonorgestrel und gegebenenfalls Estradiol |
FR2766088B1 (fr) * | 1997-07-17 | 2001-01-05 | Dow Corning Sa | Dispositifs a liberation controlee d'un agent pharmaceutique, leur fabrication par co-extrusion et article intermediaire |
FR2795326B1 (fr) * | 1999-06-28 | 2001-08-31 | Adir | Composition pharmaceutique solide thermoformable a liberation controlee |
-
1999
- 1999-06-28 FR FR9908210A patent/FR2795326B1/fr not_active Expired - Fee Related
-
2000
- 2000-06-27 DK DK00401825.5T patent/DK1064935T4/da active
- 2000-06-27 EA EA200000584A patent/EA003751B1/ru not_active IP Right Cessation
- 2000-06-27 JP JP2000193043A patent/JP2001031591A/ja active Pending
- 2000-06-27 CA CA002312545A patent/CA2312545C/fr not_active Expired - Fee Related
- 2000-06-27 DE DE60038848T patent/DE60038848D1/de not_active Expired - Lifetime
- 2000-06-27 ES ES00401825T patent/ES2307489T5/es not_active Expired - Lifetime
- 2000-06-27 EP EP00401825A patent/EP1064935B2/fr not_active Expired - Lifetime
- 2000-06-27 NZ NZ505431A patent/NZ505431A/xx not_active IP Right Cessation
- 2000-06-27 SI SI200031000T patent/SI1064935T2/sl unknown
- 2000-06-27 BR BR0002880-0A patent/BR0002880A/pt not_active Application Discontinuation
- 2000-06-27 NO NO20003349A patent/NO331449B1/no not_active IP Right Cessation
- 2000-06-27 AT AT00401825T patent/ATE395045T1/de active
- 2000-06-27 PT PT00401825T patent/PT1064935E/pt unknown
- 2000-06-27 US US09/604,500 patent/US6319520B1/en not_active Expired - Lifetime
- 2000-06-28 PL PL341042A patent/PL202494B1/pl unknown
- 2000-06-28 KR KR1020000035933A patent/KR100554899B1/ko not_active IP Right Cessation
- 2000-06-28 CN CNB001193228A patent/CN1174744C/zh not_active Expired - Fee Related
- 2000-06-28 ZA ZA200003245A patent/ZA200003245B/xx unknown
- 2000-06-28 HU HU0002469A patent/HU229342B1/hu not_active IP Right Cessation
- 2000-06-29 AU AU42734/00A patent/AU765885B2/en not_active Ceased
-
2001
- 2001-06-15 HK HK01104138A patent/HK1033435A1/xx not_active IP Right Cessation
-
2005
- 2005-12-07 JP JP2005353417A patent/JP2006077033A/ja active Pending
-
2008
- 2008-06-10 CY CY20081100615T patent/CY1110351T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
EA200000584A3 (ru) | Твердые фармацевтические композиции с контролируемым высвобождением, получаемые тепловым формованием | |
BR9916835A (pt) | Composição de galantamina de liberação controlada | |
MA30064B1 (fr) | Formulation a liberation prolongee comprenant l'octreotide et deux copolymeres de polylactide-glycolide ou plus | |
BR0212921A (pt) | Composição farmacêutica com base em fondant | |
BR0014383A (pt) | Composições de liberação controlada compreendendo nimesulida | |
DK1401501T3 (da) | Orale farmaceutiske sammensætninger med modificeret frigivelse af den aktive ingrediens | |
ATE252377T1 (de) | Kontrolliert freisetzende pharmazeutische zusammensetzung mit tilidinmesylat als wirkstoff | |
NO20032737D0 (no) | Fast termoformbar farmasöytisk sammensetning for den kontrollerte frigivelse av ivabradin | |
PT1121127E (pt) | Composicoes farmaceuticas orais contendo buprenorfina | |
SE0004053D0 (sv) | N-type calcium channel antagonists for the treatment of pain | |
PT1195160E (pt) | Composições farmacêuticas de trimetazidina de libertação sustentada e método para a sua preparação | |
EA200400628A1 (ru) | Таблетки метформина с контролируемым высвобождением активного компонента | |
ATE286894T1 (de) | 2h-1-benzopyran-derivate, prozesse zu ihrer herstellung und pharmazeutische zusammensetzungen | |
ATE280588T1 (de) | Dextran-leptin konjugate, pharmazeutische zusammentsetzungen und verbundene verfahren | |
BR0008739A (pt) | Composições de liberação controlada debeta-histina | |
YU82693A (sh) | Farmaceutske formulacije disulfonil metana i novi disulfonil metani | |
ES2170922T3 (es) | Composicion farmaceutica a base de matrices lipofilas estabilizadas para la liberacion controlada de principios activos. | |
ES2192789T3 (es) | Derivados de hidrazono-benzazuleno, composiciones farmaceuticas y compuestos intermedios. | |
WO2002092552A3 (en) | Benzamidoacetonitriles and their use as antiparasitics | |
DE60108354D1 (de) | 2H-1-Benzopyran-Derivative, Prozesse zu ihrer Herstellung und Pharmazeutische Zusammensetzungen | |
EA200300664A1 (ru) | Твердая термоформируемая фармацевтическая композиция для контролируемого высвобождения периндоприла | |
EP2266558A3 (en) | Treatment of neuropathic pain with N-methyl-D-aspartate (NMDA) receptor antagonists | |
TR199900013T2 (xx) | Yeni bile�ikler. | |
BR0212254A (pt) | Composição farmaceutica | |
SE9803277D0 (sv) | Novel compounds |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Lapse of a eurasian patent due to non-payment of renewal fees within the time limit in the following designated state(s) |
Designated state(s): AM AZ BY KZ KG MD TJ TM RU |