MX2018006287A - Inhibidores de acc de triazol y usos de los mismos. - Google Patents
Inhibidores de acc de triazol y usos de los mismos.Info
- Publication number
- MX2018006287A MX2018006287A MX2018006287A MX2018006287A MX2018006287A MX 2018006287 A MX2018006287 A MX 2018006287A MX 2018006287 A MX2018006287 A MX 2018006287A MX 2018006287 A MX2018006287 A MX 2018006287A MX 2018006287 A MX2018006287 A MX 2018006287A
- Authority
- MX
- Mexico
- Prior art keywords
- triazole
- acc inhibitors
- acc
- inhibitors
- fungicides
- Prior art date
Links
- 229940121373 acetyl-coa carboxylase inhibitor Drugs 0.000 title 1
- 150000003852 triazoles Chemical class 0.000 title 1
- 102000000452 Acetyl-CoA carboxylase Human genes 0.000 abstract 2
- 108010016219 Acetyl-CoA carboxylase Proteins 0.000 abstract 2
- 108010018763 Biotin carboxylase Proteins 0.000 abstract 2
- 208000008589 Obesity Diseases 0.000 abstract 1
- 239000000417 fungicide Substances 0.000 abstract 1
- 230000002401 inhibitory effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- -1 triazole compounds Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/93—Ligases (6)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y604/00—Ligases forming carbon-carbon bonds (6.4)
- C12Y604/01—Ligases forming carbon-carbon bonds (6.4.1)
- C12Y604/01002—Acetyl-CoA carboxylase (6.4.1.2)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Environmental Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562259966P | 2015-11-25 | 2015-11-25 | |
| PCT/US2016/063410 WO2017091617A1 (en) | 2015-11-25 | 2016-11-22 | Triazole acc inhibitors and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2018006287A true MX2018006287A (es) | 2018-09-07 |
Family
ID=57530850
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018006287A MX2018006287A (es) | 2015-11-25 | 2016-11-22 | Inhibidores de acc de triazol y usos de los mismos. |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US20170166584A1 (enExample) |
| EP (1) | EP3380479B1 (enExample) |
| JP (1) | JP2018536661A (enExample) |
| KR (1) | KR20180082557A (enExample) |
| CN (1) | CN108349994B (enExample) |
| AR (1) | AR106806A1 (enExample) |
| AU (1) | AU2016361428A1 (enExample) |
| BR (1) | BR112018010453B1 (enExample) |
| CA (1) | CA3005900C (enExample) |
| CL (1) | CL2018001360A1 (enExample) |
| CO (1) | CO2018005369A2 (enExample) |
| EA (1) | EA201890926A1 (enExample) |
| ES (1) | ES2939977T3 (enExample) |
| MX (1) | MX2018006287A (enExample) |
| PL (1) | PL3380479T3 (enExample) |
| PT (1) | PT3380479T (enExample) |
| SI (1) | SI3380479T1 (enExample) |
| WO (1) | WO2017091617A1 (enExample) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2665580T3 (es) | 2011-11-11 | 2018-04-26 | Gilead Apollo, Llc | Inhibidores de ACC y usos de los mismos |
| EP3099677A4 (en) | 2014-01-31 | 2017-07-26 | Dana-Farber Cancer Institute, Inc. | Diaminopyrimidine benzenesulfone derivatives and uses thereof |
| WO2015117087A1 (en) | 2014-01-31 | 2015-08-06 | Dana-Farber Cancer Institute, Inc. | Uses of diazepane derivatives |
| UA123946C2 (uk) | 2015-09-11 | 2021-06-30 | Дана-Фарбер Кенсер Інстітьют, Інк. | Ацетамідтієнотриазолодіазепіни й шляхи їх застосування |
| PE20181287A1 (es) | 2015-09-11 | 2018-08-07 | Dana Farber Cancer Inst Inc | Ciano tienotriazolpirazinas y usos de las mismas |
| AR106472A1 (es) | 2015-10-26 | 2018-01-17 | Gilead Apollo Llc | Inhibidores de acc y usos de los mismos |
| EA201890949A1 (ru) | 2015-11-25 | 2018-12-28 | Джилид Аполло, Ллс | СЛОЖНОЭФИРНЫЕ ИНГИБИТОРЫ АЦЕТИЛ-КоА-КАРБОКСИЛАЗЫ И ВАРИАНТЫ ИХ ПРИМЕНЕНИЯ |
| EA201890913A1 (ru) | 2015-11-25 | 2018-11-30 | Джилид Аполло, Ллс | Пиразоловые соединения в качестве ингибиторов акк и их применение |
| AU2016359626A1 (en) | 2015-11-25 | 2018-05-17 | Gilead Apollo, Llc | Fungicidal compositions containing derivatives of 2,4-dioxo-1,4-dihydrothieno(2,3-d)pyrimidine |
| KR20180082557A (ko) | 2015-11-25 | 2018-07-18 | 길리어드 아폴로, 엘엘씨 | 트리아졸 acc 억제제 및 그의 용도 |
| CA3003288A1 (en) | 2015-11-25 | 2017-06-01 | Dana-Farber Cancer Institute, Inc. | Bivalent bromodomain inhibitors and uses thereof |
| BR112018067408A2 (pt) | 2016-03-02 | 2018-12-26 | Gilead Apollo Llc | formas sólidas de um inibidor de acc de tienopirimidinadiona e métodos para a produção das mesmas |
| WO2018133858A1 (en) | 2017-01-22 | 2018-07-26 | Sunshine Lake Pharma Co., Ltd. | Thienopyrimidine derivative and use thereof in medicine |
| BR112019017915A2 (pt) | 2017-03-03 | 2020-05-12 | Gilead Apollo, Llc | Processos para a preparação de compostos fungicidas |
| CN110431143B (zh) * | 2017-03-24 | 2022-08-12 | 浙江海正药业股份有限公司 | 杂芳基并嘧啶酮类衍生物及其制备方法和用途 |
| CN110461328A (zh) | 2017-03-28 | 2019-11-15 | 吉利德科学公司 | 治疗肝疾病的治疗组合 |
| EP3655409B1 (en) * | 2017-07-17 | 2023-12-27 | Nanjing Ruijie Pharmatech Co., Ltd. | Novel compounds and their uses as acc inhibitors |
| JP2021008403A (ja) * | 2017-09-26 | 2021-01-28 | 日本曹達株式会社 | １，３，５，６−テトラ置換チエノ［２，３−ｄ］ピリミジン−２，４（１Ｈ，３Ｈ）ジオン化合物および農園芸用殺菌剤 |
| CN110950884B (zh) * | 2018-09-27 | 2024-03-26 | 上海翰森生物医药科技有限公司 | 含二并环类衍生物抑制剂、其制备方法和应用 |
| WO2020092239A1 (en) | 2018-10-29 | 2020-05-07 | Gilead Apollo, Llc | Processes for the preparation of fungicidal compounds |
| EP3669652A1 (en) | 2018-12-21 | 2020-06-24 | Bayer AG | Active compound combination |
| CN111484504B (zh) * | 2019-01-25 | 2024-05-10 | 南京圣和药业股份有限公司 | Acc抑制剂的光学异构体及其应用 |
| WO2021000242A1 (zh) * | 2019-07-02 | 2021-01-07 | 广东东阳光药业有限公司 | 具有立体构型的噻吩并嘧啶衍生物及其在药物中的应用 |
| AR119594A1 (es) | 2019-08-09 | 2021-12-29 | Gilead Sciences Inc | Derivados de tienopirimidina como inhibidores acc y usos de los mismos |
| US11478533B2 (en) | 2020-04-27 | 2022-10-25 | Novo Nordisk A/S | Semaglutide for use in medicine |
| KR20240132391A (ko) | 2020-05-05 | 2024-09-03 | 뉴베일런트, 아이엔씨. | 헤테로방향족 거대환식 에터 화학치료제 |
| KR102698413B1 (ko) | 2020-05-05 | 2024-08-26 | 뉴베일런트, 아이엔씨. | 헤테로방향족 거대환식 에터 화학치료제 |
| CN113968871A (zh) * | 2020-07-25 | 2022-01-25 | 南京圣和药业股份有限公司 | 苯基取代类acc抑制剂的晶型 |
| JP2024120189A (ja) * | 2021-07-20 | 2024-09-05 | 日産化学株式会社 | チエノウラシル化合物及び有害生物防除剤 |
| IL311444A (en) | 2021-10-01 | 2024-05-01 | Nuvalent Inc | Solid forms, pharmaceutical compositions and preparation of heteroaromatic macrocyclic ether compounds |
| CN118894803B (zh) * | 2024-09-29 | 2024-12-27 | 济南康和医药科技有限公司 | 一种吲哚布芬的合成方法 |
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-
2016
- 2016-11-22 KR KR1020187016698A patent/KR20180082557A/ko not_active Withdrawn
- 2016-11-22 US US15/359,414 patent/US20170166584A1/en not_active Abandoned
- 2016-11-22 EA EA201890926A patent/EA201890926A1/ru unknown
- 2016-11-22 PL PL16809272.4T patent/PL3380479T3/pl unknown
- 2016-11-22 CN CN201680067505.7A patent/CN108349994B/zh active Active
- 2016-11-22 BR BR112018010453-1A patent/BR112018010453B1/pt active IP Right Grant
- 2016-11-22 JP JP2018525706A patent/JP2018536661A/ja active Pending
- 2016-11-22 EP EP16809272.4A patent/EP3380479B1/en active Active
- 2016-11-22 WO PCT/US2016/063410 patent/WO2017091617A1/en not_active Ceased
- 2016-11-22 PT PT168092724T patent/PT3380479T/pt unknown
- 2016-11-22 AU AU2016361428A patent/AU2016361428A1/en not_active Abandoned
- 2016-11-22 MX MX2018006287A patent/MX2018006287A/es unknown
- 2016-11-22 CA CA3005900A patent/CA3005900C/en active Active
- 2016-11-22 SI SI201631672T patent/SI3380479T1/sl unknown
- 2016-11-22 ES ES16809272T patent/ES2939977T3/es active Active
- 2016-11-24 AR ARP160103601A patent/AR106806A1/es active IP Right Grant
-
2018
- 2018-05-18 CL CL2018001360A patent/CL2018001360A1/es unknown
- 2018-05-23 CO CONC2018/0005369A patent/CO2018005369A2/es unknown
- 2018-08-20 US US15/999,505 patent/US20190241582A1/en not_active Abandoned
-
2019
- 2019-04-24 US US16/393,454 patent/US10800791B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| BR112018010453B1 (pt) | 2022-06-14 |
| CO2018005369A2 (es) | 2018-05-31 |
| CN108349994B (zh) | 2021-06-22 |
| EP3380479B1 (en) | 2022-12-07 |
| PT3380479T (pt) | 2023-03-13 |
| SI3380479T1 (sl) | 2023-04-28 |
| CL2018001360A1 (es) | 2018-08-24 |
| US20200017519A1 (en) | 2020-01-16 |
| BR112018010453A2 (pt) | 2018-11-21 |
| KR20180082557A (ko) | 2018-07-18 |
| JP2018536661A (ja) | 2018-12-13 |
| US20170166584A1 (en) | 2017-06-15 |
| PL3380479T3 (pl) | 2023-05-08 |
| US10800791B2 (en) | 2020-10-13 |
| AR106806A1 (es) | 2018-02-21 |
| CA3005900A1 (en) | 2017-06-01 |
| CN108349994A (zh) | 2018-07-31 |
| CA3005900C (en) | 2023-10-31 |
| US20190241582A1 (en) | 2019-08-08 |
| EA201890926A1 (ru) | 2018-12-28 |
| WO2017091617A1 (en) | 2017-06-01 |
| BR112018010453A8 (pt) | 2019-02-26 |
| ES2939977T3 (es) | 2023-04-28 |
| AU2016361428A1 (en) | 2018-05-24 |
| EP3380479A1 (en) | 2018-10-03 |
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