BR112018010453A8 - ?composto, composição, e, métodos para inibição de acc, para tratamento de um fungo, parasita ou infecção bacteriana e para controle de patógenos fúngicos agrícolas? - Google Patents

?composto, composição, e, métodos para inibição de acc, para tratamento de um fungo, parasita ou infecção bacteriana e para controle de patógenos fúngicos agrícolas?

Info

Publication number
BR112018010453A8
BR112018010453A8 BR112018010453A BR112018010453A BR112018010453A8 BR 112018010453 A8 BR112018010453 A8 BR 112018010453A8 BR 112018010453 A BR112018010453 A BR 112018010453A BR 112018010453 A BR112018010453 A BR 112018010453A BR 112018010453 A8 BR112018010453 A8 BR 112018010453A8
Authority
BR
Brazil
Prior art keywords
fungal
treating
parasite
compound
composition
Prior art date
Application number
BR112018010453A
Other languages
English (en)
Other versions
BR112018010453B1 (pt
BR112018010453A2 (pt
Inventor
C Harriman Geraldine
robert greenwood Jeremy
Ghosh Shomir
Marcel Leit De Moradei Silvana
Original Assignee
Gilead Apollo Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Apollo Llc filed Critical Gilead Apollo Llc
Publication of BR112018010453A2 publication Critical patent/BR112018010453A2/pt
Publication of BR112018010453A8 publication Critical patent/BR112018010453A8/pt
Publication of BR112018010453B1 publication Critical patent/BR112018010453B1/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/93—Ligases (6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y604/00—Ligases forming carbon-carbon bonds (6.4)
    • C12Y604/01—Ligases forming carbon-carbon bonds (6.4.1)
    • C12Y604/01002—Acetyl-CoA carboxylase (6.4.1.2)

Abstract

a invenção provê compostos de triazole da fórmula (i) inibindo acetil coa carboxilase (acc), composições e usos das mesmas para o tratamento de obesidade ou como fungicidas.
BR112018010453-1A 2015-11-25 2016-11-22 Compostos triazólicos inibindores de acetil coa carboxilase (acc) BR112018010453B1 (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562259966P 2015-11-25 2015-11-25
US62/259,966 2015-11-25
PCT/US2016/063410 WO2017091617A1 (en) 2015-11-25 2016-11-22 Triazole acc inhibitors and uses thereof

Publications (3)

Publication Number Publication Date
BR112018010453A2 BR112018010453A2 (pt) 2018-11-21
BR112018010453A8 true BR112018010453A8 (pt) 2019-02-26
BR112018010453B1 BR112018010453B1 (pt) 2022-06-14

Family

ID=57530850

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112018010453-1A BR112018010453B1 (pt) 2015-11-25 2016-11-22 Compostos triazólicos inibindores de acetil coa carboxilase (acc)

Country Status (18)

Country Link
US (3) US20170166584A1 (pt)
EP (1) EP3380479B1 (pt)
JP (1) JP2018536661A (pt)
KR (1) KR20180082557A (pt)
CN (1) CN108349994B (pt)
AR (1) AR106806A1 (pt)
AU (1) AU2016361428A1 (pt)
BR (1) BR112018010453B1 (pt)
CA (1) CA3005900C (pt)
CL (1) CL2018001360A1 (pt)
CO (1) CO2018005369A2 (pt)
EA (1) EA201890926A1 (pt)
ES (1) ES2939977T3 (pt)
MX (1) MX2018006287A (pt)
PL (1) PL3380479T3 (pt)
PT (1) PT3380479T (pt)
SI (1) SI3380479T1 (pt)
WO (1) WO2017091617A1 (pt)

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US20180280394A1 (en) 2017-03-28 2018-10-04 Gilead Sciences, Inc. Methods of treating liver disease
EP3655409B1 (en) * 2017-07-17 2023-12-27 Nanjing Ruijie Pharmatech Co., Ltd. Novel compounds and their uses as acc inhibitors
JP2021008403A (ja) * 2017-09-26 2021-01-28 日本曹達株式会社 １，３，５，６−テトラ置換チエノ［２，３−ｄ］ピリミジン−２，４（１Ｈ，３Ｈ）ジオン化合物および農園芸用殺菌剤
CN110950884B (zh) * 2018-09-27 2024-03-26 上海翰森生物医药科技有限公司 含二并环类衍生物抑制剂、其制备方法和应用
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BR112018010453B1 (pt) 2022-06-14
CO2018005369A2 (es) 2018-05-31
US20200017519A1 (en) 2020-01-16
EA201890926A1 (ru) 2018-12-28
US20170166584A1 (en) 2017-06-15
ES2939977T3 (es) 2023-04-28
WO2017091617A1 (en) 2017-06-01
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JP2018536661A (ja) 2018-12-13
EP3380479B1 (en) 2022-12-07
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US10800791B2 (en) 2020-10-13
EP3380479A1 (en) 2018-10-03
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AU2016361428A1 (en) 2018-05-24
CA3005900A1 (en) 2017-06-01
MX2018006287A (es) 2018-09-07
BR112018010453A2 (pt) 2018-11-21
AR106806A1 (es) 2018-02-21
US20190241582A1 (en) 2019-08-08
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