BR112018009911A2 - composto, composição, e, métodos para inibir acc, para tratar uma infecção fúngica, parasítica ou bacteriana e para controlar patógenos fúngicos agrícolas. - Google Patents
composto, composição, e, métodos para inibir acc, para tratar uma infecção fúngica, parasítica ou bacteriana e para controlar patógenos fúngicos agrícolas.Info
- Publication number
- BR112018009911A2 BR112018009911A2 BR112018009911A BR112018009911A BR112018009911A2 BR 112018009911 A2 BR112018009911 A2 BR 112018009911A2 BR 112018009911 A BR112018009911 A BR 112018009911A BR 112018009911 A BR112018009911 A BR 112018009911A BR 112018009911 A2 BR112018009911 A2 BR 112018009911A2
- Authority
- BR
- Brazil
- Prior art keywords
- fungal
- methods
- parasitic
- treating
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
- C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
- C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Child & Adolescent Psychology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pyrane Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Furan Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Polymerisation Methods In General (AREA)
Abstract
a presente invenção provê compostos de éster úteis como inibidores de acetil coa carboxilase (acc), composições dos mesmos e métodos para uso dos mesmos.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562259975P | 2015-11-25 | 2015-11-25 | |
US62/259,975 | 2015-11-25 | ||
PCT/US2016/063388 WO2017091602A1 (en) | 2015-11-25 | 2016-11-22 | Ester acc inhibitors and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
BR112018009911A2 true BR112018009911A2 (pt) | 2018-11-13 |
BR112018009911B1 BR112018009911B1 (pt) | 2022-06-14 |
Family
ID=57518011
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BR112018009911-2A BR112018009911B1 (pt) | 2015-11-25 | 2016-11-22 | Composto ininidor de acc |
Country Status (16)
Country | Link |
---|---|
US (2) | US20170166583A1 (pt) |
EP (1) | EP3380478B1 (pt) |
JP (1) | JP2018536660A (pt) |
KR (1) | KR20180082558A (pt) |
CN (1) | CN108290902B (pt) |
AR (1) | AR106799A1 (pt) |
AU (1) | AU2016361414A1 (pt) |
BR (1) | BR112018009911B1 (pt) |
CA (1) | CA3004798C (pt) |
CL (1) | CL2018001361A1 (pt) |
CO (1) | CO2018005381A2 (pt) |
EA (1) | EA201890949A1 (pt) |
ES (1) | ES2855348T3 (pt) |
HU (1) | HUE053175T2 (pt) |
MX (1) | MX2018006288A (pt) |
WO (1) | WO2017091602A1 (pt) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HUE037444T2 (hu) | 2011-11-11 | 2018-09-28 | Gilead Apollo Llc | ACC inhibitorok és azok felhasználása |
KR20160115953A (ko) | 2014-01-31 | 2016-10-06 | 다나-파버 캔서 인스티튜트 인크. | 디아미노피리미딘 벤젠술폰 유도체 및 그의 용도 |
US10793571B2 (en) | 2014-01-31 | 2020-10-06 | Dana-Farber Cancer Institute, Inc. | Uses of diazepane derivatives |
JP2018526424A (ja) | 2015-09-11 | 2018-09-13 | ダナ−ファーバー キャンサー インスティテュート, インコーポレイテッド | アセトアミドチエノトリアゾロジアゼピンおよびこれらの使用 |
PE20181287A1 (es) | 2015-09-11 | 2018-08-07 | Dana Farber Cancer Inst Inc | Ciano tienotriazolpirazinas y usos de las mismas |
AR106472A1 (es) | 2015-10-26 | 2018-01-17 | Gilead Apollo Llc | Inhibidores de acc y usos de los mismos |
EP3379933B1 (en) | 2015-11-25 | 2023-02-15 | Gilead Apollo, LLC | Fungicidal compositions containing derivatives of 2,4-dioxo-1,4-dihydrothieno[2,3-d]pyrimidine |
BR112018010453B1 (pt) | 2015-11-25 | 2022-06-14 | Gilead Apollo, Llc | Compostos triazólicos inibindores de acetil coa carboxilase (acc) |
MX2018006288A (es) | 2015-11-25 | 2018-09-07 | Gilead Apollo Llc | Inhibidores de acc tipo ester y usos de los mismos. |
PE20181298A1 (es) | 2015-11-25 | 2018-08-07 | Dana Farber Cancer Inst Inc | Inhibidores de bromodominio bivalentes y usos de los mismos |
WO2017091600A1 (en) | 2015-11-25 | 2017-06-01 | Gilead Apollo, Llc | Pyrazole acc inhibitors and uses thereof |
CA3172549A1 (en) | 2016-03-02 | 2017-09-08 | Gilead Apollo, Llc | Solid forms of a thienopyrimidinedione acc inhibitor and methods for production thereof |
EP3571205B1 (en) | 2017-01-22 | 2023-08-30 | Sunshine Lake Pharma Co., Ltd. | Thienopyrimidine derivative and use thereof in medicine |
WO2018161008A1 (en) * | 2017-03-03 | 2018-09-07 | Gilead Apollo, Llc | Processes for the preparation of fungicidal compounds |
CN110431143B (zh) * | 2017-03-24 | 2022-08-12 | 浙江海正药业股份有限公司 | 杂芳基并嘧啶酮类衍生物及其制备方法和用途 |
ES2927019T3 (es) | 2017-03-28 | 2022-11-02 | Gilead Sciences Inc | Combinaciones terapéuticas para el tratamiento de enfermedades hepáticas |
TW202033511A (zh) | 2018-10-29 | 2020-09-16 | 美商基利阿波羅有限責任公司 | 用於製備殺真菌化合物之方法 |
EP3669652A1 (en) * | 2018-12-21 | 2020-06-24 | Bayer AG | Active compound combination |
CN111484504B (zh) * | 2019-01-25 | 2024-05-10 | 南京圣和药业股份有限公司 | Acc抑制剂的光学异构体及其应用 |
CN111747916A (zh) * | 2019-03-27 | 2020-10-09 | 尚科生物医药(上海)有限公司 | (r)-2-(2-甲氧基苯基)-2-(四氢吡喃-4-氧基)乙-1-醇的制备方法 |
AR119594A1 (es) | 2019-08-09 | 2021-12-29 | Gilead Sciences Inc | Derivados de tienopirimidina como inhibidores acc y usos de los mismos |
US11478533B2 (en) | 2020-04-27 | 2022-10-25 | Novo Nordisk A/S | Semaglutide for use in medicine |
CN113968871A (zh) * | 2020-07-25 | 2022-01-25 | 南京圣和药业股份有限公司 | 苯基取代类acc抑制剂的晶型 |
KR102597564B1 (ko) * | 2023-03-03 | 2023-11-03 | 장병모 | 조갑 및 피부 백선의 예방 또는 치료용 약학적 조성물 |
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- 2016-11-22 BR BR112018009911-2A patent/BR112018009911B1/pt active IP Right Grant
- 2016-11-22 ES ES16808884T patent/ES2855348T3/es active Active
- 2016-11-22 EP EP16808884.7A patent/EP3380478B1/en active Active
- 2016-11-22 CN CN201680067524.XA patent/CN108290902B/zh active Active
- 2016-11-22 WO PCT/US2016/063388 patent/WO2017091602A1/en active Application Filing
- 2016-11-22 HU HUE16808884A patent/HUE053175T2/hu unknown
- 2016-11-22 AU AU2016361414A patent/AU2016361414A1/en not_active Abandoned
- 2016-11-22 US US15/358,763 patent/US20170166583A1/en not_active Abandoned
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EP3380478B1 (en) | 2020-12-23 |
US11098055B2 (en) | 2021-08-24 |
EP3380478A1 (en) | 2018-10-03 |
CN108290902B (zh) | 2021-08-31 |
CA3004798A1 (en) | 2017-06-01 |
KR20180082558A (ko) | 2018-07-18 |
AR106799A1 (es) | 2018-02-21 |
HUE053175T2 (hu) | 2021-06-28 |
US20200010478A1 (en) | 2020-01-09 |
CO2018005381A2 (es) | 2018-05-31 |
MX2018006288A (es) | 2018-09-07 |
BR112018009911B1 (pt) | 2022-06-14 |
ES2855348T3 (es) | 2021-09-23 |
WO2017091602A1 (en) | 2017-06-01 |
CA3004798C (en) | 2023-10-31 |
AU2016361414A1 (en) | 2018-05-24 |
JP2018536660A (ja) | 2018-12-13 |
CL2018001361A1 (es) | 2018-08-24 |
CN108290902A (zh) | 2018-07-17 |
US20170166583A1 (en) | 2017-06-15 |
EA201890949A1 (ru) | 2018-12-28 |
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