MX2017012073A - Compuestos de minociclina para biodefensas. - Google Patents
Compuestos de minociclina para biodefensas.Info
- Publication number
- MX2017012073A MX2017012073A MX2017012073A MX2017012073A MX2017012073A MX 2017012073 A MX2017012073 A MX 2017012073A MX 2017012073 A MX2017012073 A MX 2017012073A MX 2017012073 A MX2017012073 A MX 2017012073A MX 2017012073 A MX2017012073 A MX 2017012073A
- Authority
- MX
- Mexico
- Prior art keywords
- biodefense
- bacterial infection
- minocycline compounds
- bacterium
- treating
- Prior art date
Links
- DYKFCLLONBREIL-KVUCHLLUSA-N minocycline Chemical class C([C@H]1C2)C3=C(N(C)C)C=CC(O)=C3C(=O)C1=C(O)[C@@]1(O)[C@@H]2[C@H](N(C)C)C(O)=C(C(N)=O)C1=O DYKFCLLONBREIL-KVUCHLLUSA-N 0.000 title 1
- 208000035143 Bacterial infection Diseases 0.000 abstract 4
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 4
- 241000894006 Bacteria Species 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/65—Tetracyclines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/24—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton
- C07C237/26—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a ring other than a six-membered aromatic ring of the carbon skeleton of a ring being part of a condensed ring system formed by at least four rings, e.g. tetracycline
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Communicable Diseases (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
En el presente documento se dan a conocer procedimientos para tratar o prevenir una infección bacteriana en un individuo, en donde la infección bacteriana es causada por una bacteria que puede usarse como arma biológica. También se describe una composición farmacéutica que comprende el compuesto de la presente invención para tratar o prevenir una infección bacteriana en un individuo, en donde la infección bacteriana es causada por una bacteria que puede usarse como arma biológica.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201562137719P | 2015-03-24 | 2015-03-24 | |
PCT/US2016/023807 WO2016154332A1 (en) | 2015-03-24 | 2016-03-23 | Minocycline compounds for biodefense |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2017012073A true MX2017012073A (es) | 2018-02-21 |
Family
ID=56977663
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2017012073A MX2017012073A (es) | 2015-03-24 | 2016-03-23 | Compuestos de minociclina para biodefensas. |
Country Status (14)
Country | Link |
---|---|
US (4) | US20180133231A1 (es) |
EP (2) | EP3273968B1 (es) |
JP (3) | JP6826582B2 (es) |
KR (2) | KR102656263B1 (es) |
CN (2) | CN107613988A (es) |
AU (4) | AU2016235151A1 (es) |
CA (1) | CA2980727C (es) |
ES (1) | ES2959665T3 (es) |
FI (1) | FI3273968T3 (es) |
HU (1) | HUE063795T2 (es) |
IL (1) | IL254622B2 (es) |
MX (1) | MX2017012073A (es) |
PL (1) | PL3273968T3 (es) |
WO (1) | WO2016154332A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2016154332A1 (en) * | 2015-03-24 | 2016-09-29 | Paratek Pharmaceuticals, Inc. | Minocycline compounds for biodefense |
JP7025702B2 (ja) * | 2016-03-31 | 2022-02-25 | 日産化学株式会社 | 配向層形成組成物 |
TW202206081A (zh) * | 2016-08-03 | 2022-02-16 | 美商派瑞泰Spv2有限公司 | 9—胺甲基米諾四環素化合物及其用途 |
SG11201903846TA (en) * | 2016-11-01 | 2019-05-30 | Paratek Pharm Innc | 9-aminomethyl minocycline compounds and use thereof in treating community-acquired bacterial pneumonia (cabp) |
MA52980A (fr) * | 2018-04-30 | 2021-04-28 | Melinta Therapeutics Inc | Procédés de traitement d'infections bactériennes à l'aide d'oritavancine |
CN111484424B (zh) * | 2020-04-14 | 2022-10-25 | 成都百特万合医药科技有限公司 | 一种合成奥马环素的方法 |
PT117254B (pt) | 2021-05-26 | 2024-04-18 | Hovione Farm S A | Método de síntese de compostos 9-aminometil tetraciclinas |
CN114591216A (zh) * | 2022-02-17 | 2022-06-07 | 四川澄华生物科技有限公司 | 一种合成奥马环素中间体的方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1301467B1 (en) | 2000-07-07 | 2006-08-16 | Trustees Of Tufts College | 9-substituted minocycline compounds |
US7553828B2 (en) | 2001-03-13 | 2009-06-30 | Paratek Pharmaceuticals, Inc. | 9-aminomethyl substituted minocycline compounds |
EP1496742B1 (en) * | 2002-03-29 | 2010-11-24 | The Research Foundation Of State University Of New York | Use of non-antibacterial tetracycline analogs and formulations thereof for the treatment of bacterial exotoxins |
US7943600B2 (en) * | 2004-12-20 | 2011-05-17 | Massachusetts Institute Of Technology | Antimicrobial combination therapy |
WO2007092582A2 (en) * | 2006-02-08 | 2007-08-16 | Biosynexus Incorporated | Neutralization of bacterial spores |
WO2008045507A2 (en) | 2006-10-11 | 2008-04-17 | Paratek Pharmaceuticals, Inc. | Substituted tetracycline compounds for treatment of bacillus anthracis infections |
CA2688662A1 (en) | 2007-04-27 | 2008-11-06 | Paratek Pharmaceuticals, Inc. | Methods for synthesizing and purifying aminoalkyl tetracycline compounds |
WO2009111064A2 (en) * | 2008-03-05 | 2009-09-11 | Paratek Pharmaceuticals, Inc. | Minocycline compounds and methods of use thereof |
EP2536408A1 (en) * | 2010-02-16 | 2012-12-26 | Wockhardt Research Centre | Efflux pump inhibitors |
WO2013173326A1 (en) * | 2012-05-14 | 2013-11-21 | Paratek Pharmaceuticals, Inc. | Methods of using (4s,4as,5ar,12as)-4- dimethylamino-3,10,12,12a-tetrahydroxy-7-[(methoxy(methyl)amino)-methyl]-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide |
WO2016154332A1 (en) * | 2015-03-24 | 2016-09-29 | Paratek Pharmaceuticals, Inc. | Minocycline compounds for biodefense |
-
2016
- 2016-03-23 WO PCT/US2016/023807 patent/WO2016154332A1/en active Application Filing
- 2016-03-23 EP EP16769622.8A patent/EP3273968B1/en active Active
- 2016-03-23 CN CN201680029953.8A patent/CN107613988A/zh active Pending
- 2016-03-23 EP EP23178661.7A patent/EP4268897A3/en active Pending
- 2016-03-23 CA CA2980727A patent/CA2980727C/en active Active
- 2016-03-23 JP JP2018502036A patent/JP6826582B2/ja active Active
- 2016-03-23 HU HUE16769622A patent/HUE063795T2/hu unknown
- 2016-03-23 KR KR1020177030110A patent/KR102656263B1/ko active IP Right Grant
- 2016-03-23 ES ES16769622T patent/ES2959665T3/es active Active
- 2016-03-23 MX MX2017012073A patent/MX2017012073A/es unknown
- 2016-03-23 FI FIEP16769622.8T patent/FI3273968T3/fi active
- 2016-03-23 IL IL254622A patent/IL254622B2/en unknown
- 2016-03-23 KR KR1020247011407A patent/KR20240051297A/ko not_active Application Discontinuation
- 2016-03-23 CN CN202310347377.3A patent/CN116392496A/zh active Pending
- 2016-03-23 PL PL16769622.8T patent/PL3273968T3/pl unknown
- 2016-03-23 AU AU2016235151A patent/AU2016235151A1/en not_active Abandoned
-
2017
- 2017-09-22 US US15/713,352 patent/US20180133231A1/en not_active Abandoned
-
2020
- 2020-02-24 US US16/798,500 patent/US11129839B2/en active Active
- 2020-10-28 AU AU2020260450A patent/AU2020260450B2/en active Active
- 2020-12-03 JP JP2020200877A patent/JP2021059544A/ja active Pending
-
2022
- 2022-04-04 US US17/712,585 patent/US20230098554A1/en not_active Abandoned
- 2022-10-18 AU AU2022256106A patent/AU2022256106A1/en not_active Abandoned
- 2022-11-25 JP JP2022188453A patent/JP2023022179A/ja active Pending
-
2023
- 2023-06-28 US US18/215,257 patent/US20240238315A1/en active Pending
-
2024
- 2024-04-30 AU AU2024202788A patent/AU2024202788A1/en active Pending
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