MX2014003506A - Procedimiento para producir una composición de partículas que comprende trehalosa dihidrato cristalina. - Google Patents
Procedimiento para producir una composición de partículas que comprende trehalosa dihidrato cristalina.Info
- Publication number
- MX2014003506A MX2014003506A MX2014003506A MX2014003506A MX2014003506A MX 2014003506 A MX2014003506 A MX 2014003506A MX 2014003506 A MX2014003506 A MX 2014003506A MX 2014003506 A MX2014003506 A MX 2014003506A MX 2014003506 A MX2014003506 A MX 2014003506A
- Authority
- MX
- Mexico
- Prior art keywords
- trehalose
- production method
- trehalose dihydrate
- starch
- powder containing
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
- C07H3/04—Disaccharides
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/12—Disaccharides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
- C12N9/1074—Cyclomaltodextrin glucanotransferase (2.4.1.19)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/14—Preparation of compounds containing saccharide radicals produced by the action of a carbohydrase (EC 3.2.x), e.g. by alpha-amylase, e.g. by cellulase, hemicellulase
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/18—Preparation of compounds containing saccharide radicals produced by the action of a glycosyl transferase, e.g. alpha-, beta- or gamma-cyclodextrins
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/20—Preparation of compounds containing saccharide radicals produced by the action of an exo-1,4 alpha-glucosidase, e.g. dextrose
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y204/00—Glycosyltransferases (2.4)
- C12Y204/01—Hexosyltransferases (2.4.1)
- C12Y204/01019—Cyclomaltodextrin glucanotransferase (2.4.1.19)
-
- C—CHEMISTRY; METALLURGY
- C13—SUGAR INDUSTRY
- C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
- C13K13/00—Sugars not otherwise provided for in this class
- C13K13/007—Separation of sugars provided for in subclass C13K
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Un objeto de la presente invención es proveer un procedimiento para permitir la producción de una composición de partículas que contiene trehalosa dihidrato cristalina con un rendimiento de producción más alto contra almidón, por medio de pasos consistentes usando almidón como material; el objeto anterior es resuelto suministrando un procedimiento de producción para producir una composición de partículas que contiene a,a-trehalosa dihidrato cristalina en una cantidad del 98.0% en peso o mayor, sobre una base sólida seca, caracterizado porque comprende los pasos de dejar actuar sobre almidón licuado una enzima formadora de a-a glicosiltrehalosa derivada de un microorganismo del género Arthrobacter y una enzima liberadora de trehalosa derivada d un microorganismo del género Arthrobacter junto con una enzima desramificadora de almidón y una ciclomaltodextrina glucanotransferasa; permitir actuar glucoamilasa sobre la mezcla resultante para obtener una solución de sacárido que contiene a,a-trehalosa; precipitar a,a-trehalosa dihidrato cristalina de la solución de sacárido anterior; recolectar la a,a-trehalosa dihidrato cristalina precipitada por medio de una centrífuga; y dejar envejecer y secar los cristales recolectados; en donde se usa una ciclomaltodextrina glucanotransferasa natural o recombinante del género Paenibacillus, o una enzima mutante de la misma, como la ciclomaltodextrina glucanotransferasa para aumentar el contenido de a,a-trehalosa en dicha solución de sacárido a más de 86.0% en peso, sobre una base sólida seca, sin pasar a través de un paso de fraccionamiento por cromatografía de columna.
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011206482 | 2011-09-21 | ||
| JP2012168474 | 2012-07-30 | ||
| PCT/JP2012/073266 WO2013042587A1 (ja) | 2011-09-21 | 2012-09-12 | α，α－トレハロース二含水結晶含有粉末の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| MX2014003506A true MX2014003506A (es) | 2016-02-25 |
| MX356988B MX356988B (es) | 2018-06-22 |
Family
ID=47914358
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018007700A MX2018007700A (es) | 2011-09-21 | 2012-09-12 | Procedimiento para producir una composición de partículas que comprende trehalosa dihidrato cristalina. |
| MX2014003506A MX356988B (es) | 2011-09-21 | 2012-09-12 | Procedimiento para producir una composición de partículas que comprende trehalosa dihidrato cristalina. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2018007700A MX2018007700A (es) | 2011-09-21 | 2012-09-12 | Procedimiento para producir una composición de partículas que comprende trehalosa dihidrato cristalina. |
Country Status (20)
| Country | Link |
|---|---|
| US (5) | US9657045B2 (es) |
| EP (2) | EP3404110A1 (es) |
| JP (7) | JP5647354B2 (es) |
| KR (5) | KR101570059B1 (es) |
| CN (4) | CN107446007A (es) |
| AU (2) | AU2012310757B2 (es) |
| BR (1) | BR112014006682B1 (es) |
| CA (1) | CA2849747C (es) |
| DK (1) | DK2759600T3 (es) |
| ES (1) | ES2674599T3 (es) |
| IN (1) | IN2014CN02872A (es) |
| MX (2) | MX2018007700A (es) |
| MY (2) | MY178624A (es) |
| PH (2) | PH12016501348B1 (es) |
| PL (1) | PL2759600T3 (es) |
| PT (1) | PT2759600T (es) |
| SG (3) | SG11201400808YA (es) |
| TW (4) | TWI675103B (es) |
| WO (1) | WO2013042587A1 (es) |
| ZA (1) | ZA201402839B (es) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101570059B1 (ko) * | 2011-09-21 | 2015-11-19 | 가부시기가이샤하야시바라 | α,α-트레할로스 이수화물 결정 함유 분말의 제조방법 |
| CN103981233B (zh) * | 2014-05-29 | 2015-08-26 | 湖南尔康制药股份有限公司 | 一种以木薯淀粉为原料制备海藻糖的方法 |
| CN104531629B (zh) * | 2014-12-16 | 2017-07-21 | 江南大学 | 一种提高aa‑2g转化率的环糊精葡萄糖基转移酶突变体 |
| CN115287377A (zh) * | 2016-01-20 | 2022-11-04 | 株式会社林原 | 含有α,α-海藻糖二水合物晶体的粉末、其制造方法及用途 |
| CN107739745A (zh) * | 2017-10-10 | 2018-02-27 | 溧阳维信生物科技有限公司 | 采用膜分离技术制备α,α‑海藻糖二水合物的方法 |
| CN107488689B (zh) * | 2017-10-10 | 2021-04-27 | 溧阳维信生物科技有限公司 | 采用电渗析技术制备α,α-海藻糖二水合物的方法 |
| CN108130350B (zh) * | 2018-01-26 | 2021-08-24 | 通辽梅花生物科技有限公司 | 高含量海藻糖的制备方法 |
| CN108774273B (zh) * | 2018-08-24 | 2021-06-25 | 湖南汇升生物科技有限公司 | 一种海藻糖结晶工艺 |
| CN108624637B (zh) * | 2018-08-24 | 2021-10-19 | 湖南汇升生物科技有限公司 | 一种利用大米生产海藻糖的方法 |
| CN112244184B (zh) * | 2020-09-30 | 2022-08-12 | 广东省农业科学院蚕业与农产品加工研究所 | 一种变频超声辅助水合物浓缩液态食品的装置和方法 |
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| JP2612687B2 (ja) | 1985-10-14 | 1997-05-21 | 株式会社 林原生物化学研究所 | シクロマルトデキストリングルカノトランスフエラーゼ活性を有するポリペプチド |
| JPH05292986A (ja) | 1992-02-21 | 1993-11-09 | Takeda Chem Ind Ltd | トレハロースの製造法 |
| JPH06145186A (ja) | 1992-11-05 | 1994-05-24 | Nippon Shokuhin Kako Co Ltd | α，α−トレハロースの製造法 |
| EP0691344B1 (en) | 1992-12-28 | 2003-03-19 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Purification of trehalose |
| BR9400368A (pt) | 1993-02-02 | 1994-08-23 | Ajinomoto Kk | Processo para isolamento e purificação de trehalose |
| JPH06269289A (ja) | 1993-02-02 | 1994-09-27 | Ajinomoto Co Inc | トレハロースの水晶析による単離精製法 |
| JP3559585B2 (ja) | 1993-06-03 | 2004-09-02 | 株式会社林原生物化学研究所 | トレハロース遊離酵素とその製造方法並びに用途 |
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| US5804426A (en) * | 1995-08-10 | 1998-09-08 | Iowa State University Research Foundation, Inc. | Recombinant cyclodextran glucanotransferase mutants |
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| JPH11116588A (ja) | 1997-10-16 | 1999-04-27 | Hayashibara Biochem Lab Inc | トレハロース及び糖アルコールの製造方法 |
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| KR101570059B1 (ko) * | 2011-09-21 | 2015-11-19 | 가부시기가이샤하야시바라 | α,α-트레할로스 이수화물 결정 함유 분말의 제조방법 |
| JP5993674B2 (ja) * | 2012-09-12 | 2016-09-14 | 株式会社林原 | α，α−トレハロース二含水結晶含有粉末の製造方法 |
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2012
- 2012-09-12 KR KR1020147010547A patent/KR101570059B1/ko active IP Right Review Request
- 2012-09-12 AU AU2012310757A patent/AU2012310757B2/en active Active
- 2012-09-12 WO PCT/JP2012/073266 patent/WO2013042587A1/ja active Application Filing
- 2012-09-12 CN CN201710829604.0A patent/CN107446007A/zh active Pending
- 2012-09-12 SG SG11201400808YA patent/SG11201400808YA/en unknown
- 2012-09-12 KR KR1020177024456A patent/KR101939560B1/ko active IP Right Grant
- 2012-09-12 MY MYPI2017001109A patent/MY178624A/en unknown
- 2012-09-12 MY MYPI2014700673A patent/MY160496A/en unknown
- 2012-09-12 KR KR1020207034826A patent/KR20200140392A/ko not_active Application Discontinuation
- 2012-09-12 MX MX2018007700A patent/MX2018007700A/es unknown
- 2012-09-12 DK DK12834341.5T patent/DK2759600T3/en active
- 2012-09-12 US US14/346,410 patent/US9657045B2/en active Active
- 2012-09-12 KR KR1020157023538A patent/KR101776032B1/ko active IP Right Review Request
- 2012-09-12 CN CN201510463085.1A patent/CN105218597B/zh active Active
- 2012-09-12 SG SG10201606201UA patent/SG10201606201UA/en unknown
- 2012-09-12 MX MX2014003506A patent/MX356988B/es active IP Right Grant
- 2012-09-12 JP JP2013534671A patent/JP5647354B2/ja active Active
- 2012-09-12 PL PL12834341T patent/PL2759600T3/pl unknown
- 2012-09-12 EP EP18166665.2A patent/EP3404110A1/en active Pending
- 2012-09-12 CN CN201280055581.8A patent/CN103946386B/zh active Active
- 2012-09-12 SG SG10201707535PA patent/SG10201707535PA/en unknown
- 2012-09-12 PT PT128343415T patent/PT2759600T/pt unknown
- 2012-09-12 ES ES12834341.5T patent/ES2674599T3/es active Active
- 2012-09-12 EP EP12834341.5A patent/EP2759600B1/en active Active
- 2012-09-12 KR KR1020197000862A patent/KR20190006604A/ko active Application Filing
- 2012-09-12 IN IN2872CHN2014 patent/IN2014CN02872A/en unknown
- 2012-09-12 BR BR112014006682-5A patent/BR112014006682B1/pt active IP Right Grant
- 2012-09-12 CN CN201710829642.6A patent/CN107602631A/zh active Pending
- 2012-09-12 CA CA2849747A patent/CA2849747C/en active Active
- 2012-09-19 TW TW107115788A patent/TWI675103B/zh active
- 2012-09-19 TW TW101134300A patent/TWI541346B/zh active
- 2012-09-19 TW TW105116453A patent/TWI585203B/zh active
- 2012-09-19 TW TW106107977A patent/TWI630273B/zh active
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2014
- 2014-04-16 ZA ZA2014/02839A patent/ZA201402839B/en unknown
- 2014-10-24 JP JP2014217192A patent/JP5714764B2/ja active Active
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2015
- 2015-01-19 JP JP2015007900A patent/JP5770956B2/ja active Active
- 2015-06-24 JP JP2015127104A patent/JP6045650B2/ja active Active
- 2015-12-21 US US14/976,281 patent/US9738674B2/en active Active
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2016
- 2016-06-24 AU AU2016204318A patent/AU2016204318B2/en active Active
- 2016-07-07 PH PH12016501348A patent/PH12016501348B1/en unknown
- 2016-11-15 JP JP2016222024A patent/JP6244436B2/ja active Active
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2017
- 2017-07-18 US US15/653,131 patent/US9938311B2/en active Active
- 2017-11-10 JP JP2017217819A patent/JP2018057385A/ja not_active Withdrawn
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2018
- 2018-02-26 US US15/905,407 patent/US10196416B2/en active Active
- 2018-04-02 PH PH12018500724A patent/PH12018500724B1/en unknown
- 2018-11-20 US US16/196,478 patent/US10301342B2/en active Active
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2019
- 2019-05-15 JP JP2019092483A patent/JP6770609B2/ja active Active
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