MX2011002726A - Antagonistas de pcsk9. - Google Patents
Antagonistas de pcsk9.Info
- Publication number
- MX2011002726A MX2011002726A MX2011002726A MX2011002726A MX2011002726A MX 2011002726 A MX2011002726 A MX 2011002726A MX 2011002726 A MX2011002726 A MX 2011002726A MX 2011002726 A MX2011002726 A MX 2011002726A MX 2011002726 A MX2011002726 A MX 2011002726A
- Authority
- MX
- Mexico
- Prior art keywords
- antibody
- pcsk9
- amino acid
- antibodies
- seq
- Prior art date
Links
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| JOP20080381B1 (ar) * | 2007-08-23 | 2023-03-28 | Amgen Inc | بروتينات مرتبطة بمولدات مضادات تتفاعل مع بروبروتين كونفيرتاز سيتيليزين ككسين من النوع 9 (pcsk9) |
| AR070316A1 (es) | 2008-02-07 | 2010-03-31 | Merck & Co Inc | Antagonistas de pcsk9 (proproteina subtilisina-kexina tipo 9) |
| AR070315A1 (es) | 2008-02-07 | 2010-03-31 | Merck & Co Inc | Anticuerpos 1b20 antagonistas de pcsk9 |
| EP2305300B1 (en) * | 2008-07-10 | 2016-04-06 | Toray Industries, Inc. | Pharmaceutical composition for treatment and prevention of cancer |
| US20130064834A1 (en) | 2008-12-15 | 2013-03-14 | Regeneron Pharmaceuticals, Inc. | Methods for treating hypercholesterolemia using antibodies to pcsk9 |
| US8357371B2 (en) | 2008-12-15 | 2013-01-22 | Regeneron Pharmaceuticals, Inc. | Methods for treating hypercholesterolemia using antibodies to PCSK9 |
| JO3672B1 (ar) * | 2008-12-15 | 2020-08-27 | Regeneron Pharma | أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9). |
| KR101660578B1 (ko) | 2009-09-03 | 2016-09-27 | 화이자 백신스 엘엘씨 | Ｐｃｓｋ９ 백신 |
| CA2777542A1 (en) | 2009-10-30 | 2011-05-05 | Merck Sharp & Dohme Corp. | Ax213 and ax132 pcsk9 antagonists and variants |
| AR079336A1 (es) * | 2009-12-11 | 2012-01-18 | Irm Llc | Antagonistas de la pro-proteina convertasa-subtilisina/quexina tipo 9 (pcsk9) |
| CN105175532B (zh) * | 2010-04-13 | 2023-01-17 | 百时美施贵宝公司 | 结合pcsk9的基于纤连蛋白的支架域蛋白质 |
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| GB2481373A (en) * | 2010-06-21 | 2011-12-28 | Weiming Xu | Treatment of hypercholesterolaemia by ubiquitination of PCSK9 |
| JO3756B1 (ar) | 2010-11-23 | 2021-01-31 | Regeneron Pharma | اجسام مضادة بشرية لمستقبلات الجلوكاجون |
| CA2820953A1 (en) * | 2010-12-22 | 2012-06-28 | Genentech, Inc. | Anti-pcsk9 antibodies and methods of use |
| PE20140372A1 (es) * | 2011-01-28 | 2014-03-24 | Sanofi Sa | Composiciones farmaceuticas que comprenden anticuerpos humanos frente a pcsk9 |
| BR112014000392A2 (pt) * | 2011-07-14 | 2017-02-21 | Pfizer | tratamento com anticorpos anti-pcsk9 |
| AR087305A1 (es) | 2011-07-28 | 2014-03-12 | Regeneron Pharma | Formulaciones estabilizadas que contienen anticuerpos anti-pcsk9, metodo de preparacion y kit |
| AR087715A1 (es) | 2011-09-16 | 2014-04-09 | Lilly Co Eli | Anticuerpos anti pcsk9 y usos de los mismos |
| CN103930444B (zh) * | 2011-09-16 | 2020-08-04 | 瑞泽恩制药公司 | 用前蛋白转化酶枯草溶菌素-9(PCSK9)抑制剂降低脂蛋白(a)水平的方法 |
| CA2858572C (en) | 2011-12-08 | 2023-01-17 | Amgen Inc. | Human lcat antigen binding proteins and their use in therapy |
| CA2859226C (en) * | 2011-12-20 | 2020-07-21 | Adaerata, Limited Partnership | Single domain antibodies as inhibitors of pcsk9 |
| EP3348140B1 (en) | 2012-03-16 | 2020-12-30 | Regeneron Pharmaceuticals, Inc. | Histidine engineered light chain antibodies and genetically modified rodents for generating the same |
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