BRPI0919289A2 - antagonista de pcsk9. - Google Patents
antagonista de pcsk9. Download PDFInfo
- Publication number
- BRPI0919289A2 BRPI0919289A2 BRPI0919289-1A BRPI0919289A BRPI0919289A2 BR PI0919289 A2 BRPI0919289 A2 BR PI0919289A2 BR PI0919289 A BRPI0919289 A BR PI0919289A BR PI0919289 A2 BRPI0919289 A2 BR PI0919289A2
- Authority
- BR
- Brazil
- Prior art keywords
- antibody
- pcsk9
- amino acid
- seq
- antibodies
- Prior art date
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Classifications
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A61P3/06—Antihyperlipidemics
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- C07K2299/00—Coordinates from 3D structures of peptides, e.g. proteins or enzymes
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
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- C07K2317/33—Crossreactivity, e.g. for species or epitope, or lack of said crossreactivity
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- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
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Landscapes
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- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (7)
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| US9671608P | 2008-09-12 | 2008-09-12 | |
| US61/096,716 | 2008-09-12 | ||
| US23216109P | 2009-08-07 | 2009-08-07 | |
| US61/232.161 | 2009-08-07 | ||
| US23564309P | 2009-08-20 | 2009-08-20 | |
| US61/235,643 | 2009-08-20 | ||
| PCT/IB2009/053990 WO2010029513A2 (en) | 2008-09-12 | 2009-09-11 | Pcsk9 antagonists |
Publications (1)
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| BRPI0919289A2 true BRPI0919289A2 (pt) | 2020-08-18 |
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Family Applications (1)
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| BRPI0919289-1A BRPI0919289A2 (pt) | 2008-09-12 | 2009-09-11 | antagonista de pcsk9. |
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| AR070316A1 (es) | 2008-02-07 | 2010-03-31 | Merck & Co Inc | Antagonistas de pcsk9 (proproteina subtilisina-kexina tipo 9) |
| AR070315A1 (es) | 2008-02-07 | 2010-03-31 | Merck & Co Inc | Anticuerpos 1b20 antagonistas de pcsk9 |
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