MX2010008816A - Metodo para tratar el cancer de prostata con el antagonista de gnrh degarelix. - Google Patents
Metodo para tratar el cancer de prostata con el antagonista de gnrh degarelix.Info
- Publication number
- MX2010008816A MX2010008816A MX2010008816A MX2010008816A MX2010008816A MX 2010008816 A MX2010008816 A MX 2010008816A MX 2010008816 A MX2010008816 A MX 2010008816A MX 2010008816 A MX2010008816 A MX 2010008816A MX 2010008816 A MX2010008816 A MX 2010008816A
- Authority
- MX
- Mexico
- Prior art keywords
- prostate cancer
- treating prostate
- gnrh antagonist
- gnrh
- side effect
- Prior art date
Links
- 206010060862 Prostate cancer Diseases 0.000 title abstract 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 title abstract 2
- 229940121381 gonadotrophin releasing hormone (gnrh) antagonists Drugs 0.000 title abstract 2
- 108010052004 acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ILys-prolyl-alaninamide Proteins 0.000 title 1
- MEUCPCLKGZSHTA-XYAYPHGZSA-N degarelix Chemical compound C([C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@H](C)C(N)=O)NC(=O)[C@H](CC=1C=CC(NC(=O)[C@H]2NC(=O)NC(=O)C2)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](CC=1C=NC=CC=1)NC(=O)[C@@H](CC=1C=CC(Cl)=CC=1)NC(=O)[C@@H](CC=1C=C2C=CC=CC2=CC=1)NC(C)=O)C1=CC=C(NC(N)=O)C=C1 MEUCPCLKGZSHTA-XYAYPHGZSA-N 0.000 title 1
- 229960002272 degarelix Drugs 0.000 title 1
- 239000002474 gonadorelin antagonist Substances 0.000 title 1
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 208000006820 Arthralgia Diseases 0.000 abstract 1
- 108700012941 GNRH1 Proteins 0.000 abstract 1
- 238000011292 agonist therapy Methods 0.000 abstract 1
- 239000003098 androgen Substances 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 229960003604 testosterone Drugs 0.000 abstract 1
- 208000019206 urinary tract infection Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2774108P | 2008-02-11 | 2008-02-11 | |
| EP08250703 | 2008-02-29 | ||
| PCT/IB2009/000350 WO2009101530A1 (en) | 2008-02-11 | 2009-02-10 | Method of treating prostate cancer with the gnrh antagonist degarelix |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010008816A true MX2010008816A (es) | 2010-09-07 |
Family
ID=39718285
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010008816A MX2010008816A (es) | 2008-02-11 | 2009-02-10 | Metodo para tratar el cancer de prostata con el antagonista de gnrh degarelix. |
| MX2010008817A MX2010008817A (es) | 2008-02-11 | 2009-02-10 | Tratamiento de cancer de prostata en etapa metastatica con degarelix. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010008817A MX2010008817A (es) | 2008-02-11 | 2009-02-10 | Tratamiento de cancer de prostata en etapa metastatica con degarelix. |
Country Status (25)
| Country | Link |
|---|---|
| US (18) | US20090203623A1 (enExample) |
| EP (7) | EP2505204B1 (enExample) |
| JP (12) | JP5924866B2 (enExample) |
| KR (8) | KR20140130757A (enExample) |
| CN (4) | CN101939020B (enExample) |
| AU (2) | AU2009213748B9 (enExample) |
| BR (2) | BRPI0908129A2 (enExample) |
| CA (3) | CA2714444A1 (enExample) |
| CY (3) | CY1115561T1 (enExample) |
| DK (3) | DK2505204T3 (enExample) |
| EA (4) | EA036695B1 (enExample) |
| ES (3) | ES2540235T3 (enExample) |
| HK (1) | HK1198243A1 (enExample) |
| HR (3) | HRP20140665T1 (enExample) |
| IL (3) | IL207295A (enExample) |
| JO (1) | JOP20090061B1 (enExample) |
| MX (2) | MX2010008816A (enExample) |
| NZ (4) | NZ603958A (enExample) |
| PL (3) | PL2650012T3 (enExample) |
| PT (3) | PT2505204E (enExample) |
| RU (2) | RU2504393C2 (enExample) |
| SI (3) | SI2249859T1 (enExample) |
| TW (2) | TWI442932B (enExample) |
| WO (2) | WO2009101533A1 (enExample) |
| ZA (1) | ZA201005697B (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0117057D0 (en) * | 2001-07-12 | 2001-09-05 | Ferring Bv | Pharmaceutical composition |
| TWI442932B (zh) | 2008-02-11 | 2014-07-01 | Ferring Int Ct Sa | 以GnRH拮抗劑治療攝護腺癌的方法 |
| JO3525B1 (ar) * | 2008-02-11 | 2020-07-05 | Ferring Int Center Sa | علاج سرطان البروستاتا في المرحلة النقيلية بدواء ديجاريليكس |
| KR101795643B1 (ko) * | 2009-05-01 | 2017-11-09 | 훼링 비.브이. | 전립선암 치료용 조성물 |
| TW201043221A (en) * | 2009-05-06 | 2010-12-16 | Ferring Int Ct Sa | Kit and method for preparation of a Degarelix solution |
| US20110039787A1 (en) * | 2009-07-06 | 2011-02-17 | Ferring International Center S.A. | Compositions, kits and methods for treating benign prostate hyperplasia |
| FR2964323B1 (fr) * | 2010-09-08 | 2012-11-09 | Jean Pierre Raynaud | Utilisation de la testosterone chez un patient en deficit androgenique et atteint d'un cancer de la prostate |
| EP2447276A1 (en) | 2010-10-27 | 2012-05-02 | Ferring B.V. | Process for the manufacture of Degarelix and its intermediates |
| WO2012055903A1 (en) | 2010-10-27 | 2012-05-03 | Ferring B.V. | Process for the manufacture of degarelix and its intermediates |
| JO3755B1 (ar) | 2011-01-26 | 2021-01-31 | Ferring Bv | تركيبات تستوستيرون |
| US10952415B2 (en) | 2011-03-09 | 2021-03-23 | Richard G. Pestell | Prostate cancer cell lines, gene signatures and uses thereof |
| CN102204889B (zh) * | 2011-05-23 | 2013-09-18 | 蚌埠丰原涂山制药有限公司 | 一种醋酸地加瑞克冻干粉针剂及其制备方法 |
| WO2013104745A1 (en) * | 2012-01-13 | 2013-07-18 | Ferring Bv | Pharmaceutical composition |
| HK1209673A1 (en) | 2012-05-14 | 2016-04-08 | Prostagene Llc | Using modulators of ccr5 for treating cancer |
| KR102140982B1 (ko) | 2012-06-01 | 2020-08-05 | 훼링 비.브이. | 데가렐릭스의 제조 방법 |
| WO2014052237A1 (en) | 2012-09-26 | 2014-04-03 | Aragon Pharmaceuticals, Inc. | Anti-androgens for the treatment of non-metastatic castrate-resistant prostate cancer |
| SMT202200255T1 (it) | 2012-09-28 | 2022-07-21 | Takeda Pharmaceuticals Co | Forma cristallina di 1-(4-1-(2,6-difluorobenzil)-5-dimetilamminometil-3-(6-metossipiridazin-3-il)-2,4-diosso-1,2,3,4-tetraidrotieno(2,3-d)-pirimidin-6il)fenil)-3-metossiurea |
| EP4223298A3 (en) | 2013-03-15 | 2023-08-16 | AbbVie Inc. | Compositions for use in treating heavy menstrual bleeding |
| WO2014186608A1 (en) * | 2013-05-15 | 2014-11-20 | Adverse Events, Inc. | System and method for surveillance and evaluation of safety risks associated with medical interventions |
| AU2015308987B2 (en) * | 2014-08-26 | 2021-02-18 | Kaass Discovery As | Methods, agents and compositions for treatment of inflammatory conditions |
| JP6941565B2 (ja) | 2015-05-12 | 2021-09-29 | ドレクセル ユニバーシティ | がん転移を処置または防止するのに有用な化合物および組成物、ならびにこれらの使用法 |
| SI3518932T1 (sl) | 2016-09-30 | 2025-03-31 | Takeda Pharmaceutical Company Limited | Zdravljenje raka prostate |
| JP6990717B2 (ja) * | 2017-01-30 | 2022-02-03 | アンテヴ リミテッド | 少なくとも1種のgnrhアンタゴニストを含む組成物 |
| KR20240096623A (ko) | 2017-10-16 | 2024-06-26 | 아라곤 파마슈티컬스, 인코포레이티드 | 비-전이성 거세-저항성 전립선암의 치료를 위한 항-안드로겐 |
| US11690854B2 (en) | 2018-04-19 | 2023-07-04 | Abbvie Inc. | Methods of treating heavy menstrual bleeding |
| CA3107597A1 (en) * | 2018-08-01 | 2020-02-06 | Abbvie Inc. | Dosing regimens for elagolix |
| RU2731002C1 (ru) * | 2019-10-22 | 2020-08-26 | Государственное бюджетное учреждение здравоохранения Московской области "Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского" (ГБУЗ МО МОНИКИ им. М.Ф. Владимирского) | Способ лечения рака предстательной железы |
| CN116407494B (zh) * | 2023-03-02 | 2024-07-09 | 山东大学齐鲁医院 | 一种醋酸地加瑞克注射液及其制备方法、用途 |
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| ATE144538T1 (de) | 1991-04-25 | 1996-11-15 | Romano Deghenghi | Lhrh-antagonisten |
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| US7229774B2 (en) | 2001-08-02 | 2007-06-12 | Regents Of The University Of Michigan | Expression profile of prostate cancer |
| US20070015713A1 (en) | 2005-07-14 | 2007-01-18 | Voyager Pharmaceutical Corporation | Methods for treating prostate cancer |
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| TWI442932B (zh) * | 2008-02-11 | 2014-07-01 | Ferring Int Ct Sa | 以GnRH拮抗劑治療攝護腺癌的方法 |
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| EP2421887B1 (en) | 2009-04-24 | 2015-04-22 | Polypeptide Laboratories A/S | Method for the manufacture of degarelix |
| KR101795643B1 (ko) * | 2009-05-01 | 2017-11-09 | 훼링 비.브이. | 전립선암 치료용 조성물 |
| TW201043221A (en) * | 2009-05-06 | 2010-12-16 | Ferring Int Ct Sa | Kit and method for preparation of a Degarelix solution |
| US20110039787A1 (en) * | 2009-07-06 | 2011-02-17 | Ferring International Center S.A. | Compositions, kits and methods for treating benign prostate hyperplasia |
| WO2011066386A1 (en) | 2009-11-25 | 2011-06-03 | Novetide, Ltd. | Process for production of degarelix |
| IT1399892B1 (it) | 2010-03-15 | 2013-05-09 | Spi Tecno Srl | Sistema per l illuminazione pubblica |
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| WO2012055903A1 (en) * | 2010-10-27 | 2012-05-03 | Ferring B.V. | Process for the manufacture of degarelix and its intermediates |
| EP2447276A1 (en) | 2010-10-27 | 2012-05-02 | Ferring B.V. | Process for the manufacture of Degarelix and its intermediates |
| JO3755B1 (ar) * | 2011-01-26 | 2021-01-31 | Ferring Bv | تركيبات تستوستيرون |
| CN102204889B (zh) | 2011-05-23 | 2013-09-18 | 蚌埠丰原涂山制药有限公司 | 一种醋酸地加瑞克冻干粉针剂及其制备方法 |
| EP2731607B1 (en) * | 2011-07-15 | 2017-10-11 | Ferring B.V. | Method for timing a colonoscopy wherein a picosulate composition is administered |
| KR102140982B1 (ko) | 2012-06-01 | 2020-08-05 | 훼링 비.브이. | 데가렐릭스의 제조 방법 |
-
2009
- 2009-02-09 TW TW098104075A patent/TWI442932B/zh active
- 2009-02-09 JO JOP/2009/0061A patent/JOP20090061B1/ar active
- 2009-02-09 TW TW098104073A patent/TWI539959B/zh active
- 2009-02-10 EA EA201300741A patent/EA036695B1/ru not_active IP Right Cessation
- 2009-02-10 CN CN200980104713XA patent/CN101939020B/zh not_active Ceased
- 2009-02-10 DK DK12165896T patent/DK2505204T3/da active
- 2009-02-10 EP EP12165896.7A patent/EP2505204B1/en not_active Revoked
- 2009-02-10 PT PT12165896T patent/PT2505204E/pt unknown
- 2009-02-10 BR BRPI0908129-1A patent/BRPI0908129A2/pt not_active Application Discontinuation
- 2009-02-10 EP EP23174353.5A patent/EP4257197A3/en active Pending
- 2009-02-10 CN CN2009801127793A patent/CN101998861A/zh active Pending
- 2009-02-10 NZ NZ603958A patent/NZ603958A/xx unknown
- 2009-02-10 KR KR1020147030003A patent/KR20140130757A/ko not_active Ceased
- 2009-02-10 RU RU2010133481/15A patent/RU2504393C2/ru active
- 2009-02-10 AU AU2009213748A patent/AU2009213748B9/en active Active
- 2009-02-10 WO PCT/IB2009/000370 patent/WO2009101533A1/en not_active Ceased
- 2009-02-10 PT PT97113906T patent/PT2249859E/pt unknown
- 2009-02-10 SI SI200930942T patent/SI2249859T1/sl unknown
- 2009-02-10 EP EP13168404.5A patent/EP2650012B1/en not_active Revoked
- 2009-02-10 NZ NZ587057A patent/NZ587057A/xx unknown
- 2009-02-10 JP JP2010545575A patent/JP5924866B2/ja active Active
- 2009-02-10 CN CN201710169651.7A patent/CN107412726A/zh active Pending
- 2009-02-10 SI SI200931181T patent/SI2650012T1/sl unknown
- 2009-02-10 PL PL13168404T patent/PL2650012T3/pl unknown
- 2009-02-10 KR KR1020107020036A patent/KR20100123714A/ko not_active Ceased
- 2009-02-10 AU AU2009213751A patent/AU2009213751B2/en active Active
- 2009-02-10 DK DK09711390.6T patent/DK2249859T3/da active
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