MX2010008816A - Metodo para tratar el cancer de prostata con el antagonista de gnrh degarelix. - Google Patents
Metodo para tratar el cancer de prostata con el antagonista de gnrh degarelix.Info
- Publication number
- MX2010008816A MX2010008816A MX2010008816A MX2010008816A MX2010008816A MX 2010008816 A MX2010008816 A MX 2010008816A MX 2010008816 A MX2010008816 A MX 2010008816A MX 2010008816 A MX2010008816 A MX 2010008816A MX 2010008816 A MX2010008816 A MX 2010008816A
- Authority
- MX
- Mexico
- Prior art keywords
- prostate cancer
- treating prostate
- gnrh antagonist
- gnrh
- side effect
- Prior art date
Links
- 206010060862 Prostate cancer Diseases 0.000 title abstract 2
- 208000000236 Prostatic Neoplasms Diseases 0.000 title abstract 2
- 229940121381 gonadotrophin releasing hormone (gnrh) antagonists Drugs 0.000 title abstract 2
- 108010052004 acetyl-2-naphthylalanyl-3-chlorophenylalanyl-1-oxohexadecyl-seryl-4-aminophenylalanyl(hydroorotyl)-4-aminophenylalanyl(carbamoyl)-leucyl-ILys-prolyl-alaninamide Proteins 0.000 title 1
- MEUCPCLKGZSHTA-XYAYPHGZSA-N degarelix Chemical compound C([C@H](C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCNC(C)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@H](C)C(N)=O)NC(=O)[C@H](CC=1C=CC(NC(=O)[C@H]2NC(=O)NC(=O)C2)=CC=1)NC(=O)[C@H](CO)NC(=O)[C@@H](CC=1C=NC=CC=1)NC(=O)[C@@H](CC=1C=CC(Cl)=CC=1)NC(=O)[C@@H](CC=1C=C2C=CC=CC2=CC=1)NC(C)=O)C1=CC=C(NC(N)=O)C=C1 MEUCPCLKGZSHTA-XYAYPHGZSA-N 0.000 title 1
- 229960002272 degarelix Drugs 0.000 title 1
- 239000002474 gonadorelin antagonist Substances 0.000 title 1
- MUMGGOZAMZWBJJ-DYKIIFRCSA-N Testostosterone Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CCC2=C1 MUMGGOZAMZWBJJ-DYKIIFRCSA-N 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 208000006820 Arthralgia Diseases 0.000 abstract 1
- 108700012941 GNRH1 Proteins 0.000 abstract 1
- 238000011292 agonist therapy Methods 0.000 abstract 1
- 239000003098 androgen Substances 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 230000002526 effect on cardiovascular system Effects 0.000 abstract 1
- 229960003604 testosterone Drugs 0.000 abstract 1
- 208000019206 urinary tract infection Diseases 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Reproductive Health (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Steroid Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2774108P | 2008-02-11 | 2008-02-11 | |
| EP08250703 | 2008-02-29 | ||
| PCT/IB2009/000350 WO2009101530A1 (en) | 2008-02-11 | 2009-02-10 | Method of treating prostate cancer with the gnrh antagonist degarelix |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2010008816A true MX2010008816A (es) | 2010-09-07 |
Family
ID=39718285
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010008816A MX2010008816A (es) | 2008-02-11 | 2009-02-10 | Metodo para tratar el cancer de prostata con el antagonista de gnrh degarelix. |
| MX2010008817A MX2010008817A (es) | 2008-02-11 | 2009-02-10 | Tratamiento de cancer de prostata en etapa metastatica con degarelix. |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2010008817A MX2010008817A (es) | 2008-02-11 | 2009-02-10 | Tratamiento de cancer de prostata en etapa metastatica con degarelix. |
Country Status (25)
| Country | Link |
|---|---|
| US (17) | US20090203623A1 (enExample) |
| EP (7) | EP4257197A3 (enExample) |
| JP (11) | JP5924866B2 (enExample) |
| KR (8) | KR20180118830A (enExample) |
| CN (4) | CN101939020B (enExample) |
| AU (2) | AU2009213751B2 (enExample) |
| BR (2) | BRPI0908129A2 (enExample) |
| CA (3) | CA2714444A1 (enExample) |
| CY (3) | CY1115561T1 (enExample) |
| DK (3) | DK2650012T3 (enExample) |
| EA (4) | EA020543B1 (enExample) |
| ES (3) | ES2479441T3 (enExample) |
| HK (1) | HK1198243A1 (enExample) |
| HR (3) | HRP20140665T1 (enExample) |
| IL (3) | IL207295A (enExample) |
| JO (1) | JOP20090061B1 (enExample) |
| MX (2) | MX2010008816A (enExample) |
| NZ (4) | NZ603932A (enExample) |
| PL (3) | PL2505204T3 (enExample) |
| PT (3) | PT2249859E (enExample) |
| RU (2) | RU2504394C2 (enExample) |
| SI (3) | SI2505204T1 (enExample) |
| TW (2) | TWI539959B (enExample) |
| WO (2) | WO2009101533A1 (enExample) |
| ZA (1) | ZA201005697B (enExample) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0117057D0 (en) * | 2001-07-12 | 2001-09-05 | Ferring Bv | Pharmaceutical composition |
| TWI539959B (zh) | 2008-02-11 | 2016-07-01 | 菲瑞茵國際中心股份有限公司 | 治療轉移階段攝護腺癌的方法 |
| JO3525B1 (ar) * | 2008-02-11 | 2020-07-05 | Ferring Int Center Sa | علاج سرطان البروستاتا في المرحلة النقيلية بدواء ديجاريليكس |
| US8722088B2 (en) * | 2009-05-01 | 2014-05-13 | Ferring International Center S.A. | Pharmaceutical compositions and methods for the treatment of prostate cancer |
| TW201043221A (en) * | 2009-05-06 | 2010-12-16 | Ferring Int Ct Sa | Kit and method for preparation of a Degarelix solution |
| US20110039787A1 (en) * | 2009-07-06 | 2011-02-17 | Ferring International Center S.A. | Compositions, kits and methods for treating benign prostate hyperplasia |
| FR2964323B1 (fr) * | 2010-09-08 | 2012-11-09 | Jean Pierre Raynaud | Utilisation de la testosterone chez un patient en deficit androgenique et atteint d'un cancer de la prostate |
| WO2012055903A1 (en) | 2010-10-27 | 2012-05-03 | Ferring B.V. | Process for the manufacture of degarelix and its intermediates |
| EP2447276A1 (en) | 2010-10-27 | 2012-05-02 | Ferring B.V. | Process for the manufacture of Degarelix and its intermediates |
| JO3755B1 (ar) | 2011-01-26 | 2021-01-31 | Ferring Bv | تركيبات تستوستيرون |
| MX2013010330A (es) | 2011-03-09 | 2014-11-26 | Richard G Pestell | Líneas de célula cancerosa de próstata, signaturas de gen, y usos de las mismas. |
| CN102204889B (zh) * | 2011-05-23 | 2013-09-18 | 蚌埠丰原涂山制药有限公司 | 一种醋酸地加瑞克冻干粉针剂及其制备方法 |
| WO2013104745A1 (en) * | 2012-01-13 | 2013-07-18 | Ferring Bv | Pharmaceutical composition |
| HK1209673A1 (en) | 2012-05-14 | 2016-04-08 | Prostagene Llc | Using modulators of ccr5 for treating cancer |
| EP2854831B1 (en) | 2012-06-01 | 2024-07-10 | Ferring B.V. | Manufacture of degarelix |
| PT3305285T (pt) | 2012-09-26 | 2020-11-24 | Aragon Pharmaceuticals Inc | Antiandrogénios para o tratamento de cancro da próstata resistente à castração não metastático |
| HUE044048T2 (hu) | 2012-09-28 | 2019-09-30 | Takeda Pharmaceuticals Co | Eljárás tienopirimidin származék elõállítására |
| CA2906894A1 (en) | 2013-03-15 | 2014-09-18 | Abbvie Inc. | Compositions comprising elagolix for use in treating pain associated with endometriosis |
| US20140358576A1 (en) * | 2013-05-15 | 2014-12-04 | Adverse Events, Inc. | System and method for surveillance and evaluation of safety risks associated with medical interventions |
| EP3185881B1 (en) * | 2014-08-26 | 2022-03-09 | Betanien Hospital | Methods, agents and compositions for treatment of inflammatory conditions |
| AU2016261770B2 (en) * | 2015-05-12 | 2022-06-02 | Drexel University | Compounds and compositions useful for treating or preventing cancer metastasis, and methods using same |
| HUE070578T2 (hu) | 2016-09-30 | 2025-06-28 | Sumitomo Pharma Switzerland Gmbh | Prosztatarák kezelése |
| CN110248679A (zh) * | 2017-01-30 | 2019-09-17 | 安迪威有限公司 | 包含至少一种GnRH拮抗剂的组合物 |
| EP4438126A3 (en) | 2017-10-16 | 2025-01-01 | Aragon Pharmaceuticals, Inc. | Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer |
| CN112261942A (zh) | 2018-04-19 | 2021-01-22 | 艾伯维公司 | 治疗重度月经出血的方法 |
| WO2020028630A1 (en) * | 2018-08-01 | 2020-02-06 | Abbvie Inc. | Dosing regimens for elagolix |
| RU2731002C1 (ru) * | 2019-10-22 | 2020-08-26 | Государственное бюджетное учреждение здравоохранения Московской области "Московский областной научно-исследовательский клинический институт им. М.Ф. Владимирского" (ГБУЗ МО МОНИКИ им. М.Ф. Владимирского) | Способ лечения рака предстательной железы |
| CN116407494B (zh) * | 2023-03-02 | 2024-07-09 | 山东大学齐鲁医院 | 一种醋酸地加瑞克注射液及其制备方法、用途 |
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| US5296468A (en) | 1989-10-30 | 1994-03-22 | The Salk Institute For Biological Studies | GnRH analogs |
| ATE144538T1 (de) | 1991-04-25 | 1996-11-15 | Romano Deghenghi | Lhrh-antagonisten |
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| US7229774B2 (en) | 2001-08-02 | 2007-06-12 | Regents Of The University Of Michigan | Expression profile of prostate cancer |
| US20060234918A1 (en) * | 2001-12-19 | 2006-10-19 | Voyager Pharmaceutical Corporation | Methods for treating and preventing cancers that express the hypothalamic-pituitary-gonadal axis of hormones and receptors |
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| WO2006069779A1 (en) | 2004-12-30 | 2006-07-06 | F. Hoffmann-La Roche Ag | Preparing of peptides with excellent solubility |
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| EP1891964A1 (en) | 2006-08-08 | 2008-02-27 | AEterna Zentaris GmbH | Application of initial doses of LHRH analogues and maintenance doses of LHRH antagonists for the treatment of hormone-dependent cancers and corresponding pharmaceutical kits |
| EP1967202A1 (en) | 2007-03-05 | 2008-09-10 | AEterna Zentaris GmbH | Use of LHRH Antagonists for the Treatment of Lower Urinary Tract Symptoms, in particular Overactive Bladder and/or Detrusor Overactivity |
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| US8283331B2 (en) | 2007-10-09 | 2012-10-09 | Children's Medical Center Corporation | Methods to regulate miRNA processing by targeting Lin-28 |
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| WO2009102720A1 (en) * | 2008-02-11 | 2009-08-20 | Safety Syringes, Inc. | Reconstitution means for safety device |
| TWI539959B (zh) * | 2008-02-11 | 2016-07-01 | 菲瑞茵國際中心股份有限公司 | 治療轉移階段攝護腺癌的方法 |
| ES2538828T3 (es) | 2009-04-24 | 2015-06-24 | Polypeptide Laboratories A/S | Método para la fabricación de degarelix |
| US8722088B2 (en) * | 2009-05-01 | 2014-05-13 | Ferring International Center S.A. | Pharmaceutical compositions and methods for the treatment of prostate cancer |
| TW201043221A (en) * | 2009-05-06 | 2010-12-16 | Ferring Int Ct Sa | Kit and method for preparation of a Degarelix solution |
| US20110039787A1 (en) | 2009-07-06 | 2011-02-17 | Ferring International Center S.A. | Compositions, kits and methods for treating benign prostate hyperplasia |
| WO2011066386A1 (en) | 2009-11-25 | 2011-06-03 | Novetide, Ltd. | Process for production of degarelix |
| ES2385240B1 (es) | 2010-07-26 | 2013-09-23 | Gp-Pharm, S.A. | Cápsulas de principios activos farmacéuticos y ácidos grasos poliinsaturados para el tratamiento de enfermedades de la próstata. |
| EP2447276A1 (en) | 2010-10-27 | 2012-05-02 | Ferring B.V. | Process for the manufacture of Degarelix and its intermediates |
| WO2012055903A1 (en) * | 2010-10-27 | 2012-05-03 | Ferring B.V. | Process for the manufacture of degarelix and its intermediates |
| JO3755B1 (ar) * | 2011-01-26 | 2021-01-31 | Ferring Bv | تركيبات تستوستيرون |
| CN102204889B (zh) | 2011-05-23 | 2013-09-18 | 蚌埠丰原涂山制药有限公司 | 一种醋酸地加瑞克冻干粉针剂及其制备方法 |
| CN103841970A (zh) * | 2011-07-15 | 2014-06-04 | 辉凌公司 | 其中施用匹可硫酸盐组合物的结肠镜检查定时方法 |
| EP2854831B1 (en) | 2012-06-01 | 2024-07-10 | Ferring B.V. | Manufacture of degarelix |
-
2009
- 2009-02-09 TW TW098104073A patent/TWI539959B/zh active
- 2009-02-09 JO JOP/2009/0061A patent/JOP20090061B1/ar active
- 2009-02-09 TW TW098104075A patent/TWI442932B/zh active
- 2009-02-10 DK DK13168404.5T patent/DK2650012T3/da active
- 2009-02-10 HR HRP20140665AT patent/HRP20140665T1/hr unknown
- 2009-02-10 PT PT97113906T patent/PT2249859E/pt unknown
- 2009-02-10 CN CN200980104713XA patent/CN101939020B/zh not_active Ceased
- 2009-02-10 PL PL12165896T patent/PL2505204T3/pl unknown
- 2009-02-10 NZ NZ603932A patent/NZ603932A/en unknown
- 2009-02-10 US US12/368,935 patent/US20090203623A1/en not_active Abandoned
- 2009-02-10 EP EP23174353.5A patent/EP4257197A3/en active Pending
- 2009-02-10 CN CN201710169651.7A patent/CN107412726A/zh active Pending
- 2009-02-10 EP EP18151844.0A patent/EP3360565A1/en active Pending
- 2009-02-10 KR KR1020187030959A patent/KR20180118830A/ko not_active Ceased
- 2009-02-10 SI SI200931138T patent/SI2505204T1/sl unknown
- 2009-02-10 ES ES09711390.6T patent/ES2479441T3/es active Active
- 2009-02-10 SI SI200931181T patent/SI2650012T1/sl unknown
- 2009-02-10 AU AU2009213751A patent/AU2009213751B2/en active Active
- 2009-02-10 KR KR1020107020035A patent/KR101542480B1/ko active Active
- 2009-02-10 KR KR1020257005826A patent/KR20250028541A/ko active Pending
- 2009-02-10 EA EA200901075A patent/EA020543B1/ru unknown
- 2009-02-10 EP EP09711390.6A patent/EP2249859B1/en not_active Revoked
- 2009-02-10 PT PT12165896T patent/PT2505204E/pt unknown
- 2009-02-10 KR KR1020157020657A patent/KR20150091543A/ko not_active Ceased
- 2009-02-10 CA CA2714444A patent/CA2714444A1/en active Pending
- 2009-02-10 CA CA3235099A patent/CA3235099A1/en active Pending
- 2009-02-10 CN CN2009801127793A patent/CN101998861A/zh active Pending
- 2009-02-10 RU RU2010133480/15A patent/RU2504394C2/ru active
- 2009-02-10 WO PCT/IB2009/000370 patent/WO2009101533A1/en not_active Ceased
- 2009-02-10 PT PT131684045T patent/PT2650012E/pt unknown
- 2009-02-10 ES ES12165896.7T patent/ES2532709T3/es active Active
- 2009-02-10 EA EA200901074A patent/EA017582B1/ru not_active IP Right Cessation
- 2009-02-10 PL PL13168404T patent/PL2650012T3/pl unknown
- 2009-02-10 KR KR1020237019555A patent/KR20230088848A/ko not_active Ceased
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