MX2009006540A - Derivados de ester y amida de indazolilo para el tratamiento de enfermedades mediadas por un receptor de glucocorticoides. - Google Patents
Derivados de ester y amida de indazolilo para el tratamiento de enfermedades mediadas por un receptor de glucocorticoides.Info
- Publication number
- MX2009006540A MX2009006540A MX2009006540A MX2009006540A MX2009006540A MX 2009006540 A MX2009006540 A MX 2009006540A MX 2009006540 A MX2009006540 A MX 2009006540A MX 2009006540 A MX2009006540 A MX 2009006540A MX 2009006540 A MX2009006540 A MX 2009006540A
- Authority
- MX
- Mexico
- Prior art keywords
- treatment
- amide derivatives
- glucocorticoid receptor
- receptor mediated
- mediated disorders
- Prior art date
Links
- -1 Indazolyl ester Chemical class 0.000 title abstract 2
- 150000001408 amides Chemical class 0.000 title abstract 2
- 102000003676 Glucocorticoid Receptors Human genes 0.000 title 1
- 108090000079 Glucocorticoid Receptors Proteins 0.000 title 1
- 230000001404 mediated effect Effects 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
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- Health & Medical Sciences (AREA)
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- Life Sciences & Earth Sciences (AREA)
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- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
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- Oncology (AREA)
- Obesity (AREA)
- Urology & Nephrology (AREA)
- Otolaryngology (AREA)
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Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US87118406P | 2006-12-21 | 2006-12-21 | |
| US94174507P | 2007-06-04 | 2007-06-04 | |
| US97852607P | 2007-10-09 | 2007-10-09 | |
| PCT/SE2007/001136 WO2008076048A1 (en) | 2006-12-21 | 2007-12-20 | Indazolyl ester and amide derivatives for the treatment of glucocorticoid receptor mediated disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| MX2009006540A true MX2009006540A (es) | 2009-06-30 |
Family
ID=39536557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| MX2009006540A MX2009006540A (es) | 2006-12-21 | 2007-12-20 | Derivados de ester y amida de indazolilo para el tratamiento de enfermedades mediadas por un receptor de glucocorticoides. |
Country Status (36)
Families Citing this family (43)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH081035Y2 (ja) | 1993-06-30 | 1996-01-17 | 伸夫 高橋 | 家庭用雑排水の処理装置 |
| FR2866886B1 (fr) * | 2004-02-26 | 2007-08-31 | Sanofi Synthelabo | Derives d'aryl-et d'heteroaryl-akylcarbamates, leur preparation et leur application en therapeutique |
| TW200829578A (en) | 2006-11-23 | 2008-07-16 | Astrazeneca Ab | Chemical compounds 537 |
| JO2754B1 (en) | 2006-12-21 | 2014-03-15 | استرازينكا ايه بي | Amylendazoleil derivatives for the treatment of glucocorticoid-mediated disorders |
| WO2009142568A1 (en) * | 2008-05-20 | 2009-11-26 | Astrazeneca Ab | Combination of (a) glucocorticoid receptor modulator and (b) a b2-agonist |
| WO2009142588A1 (en) * | 2008-05-20 | 2009-11-26 | Astrazeneca Ab | Combination of (a) a chemokine receptor 1 (ccr1) antagonist and (b) glucocorticoid receptor modulator |
| WO2009142589A1 (en) * | 2008-05-20 | 2009-11-26 | Astrazeneca Ab | Combination of (a) glucocorticoid receptor modulator and (b) a muscarinic antagonist |
| UY31832A (es) * | 2008-05-20 | 2010-01-05 | Astrazeneca Ab | Derivados de indazol sustituidos con fenilo y benzodioxinilo |
| WO2010008341A1 (en) * | 2008-07-16 | 2010-01-21 | Astrazeneca Ab | A combination of (a) glucocorticoid receptor modulator and (b) a muscarinic antagonist |
| WO2010138421A1 (en) * | 2009-05-27 | 2010-12-02 | Merck Sharp & Dohme Corp. | HEXAHYDROCYCLOPENTYL[f]INDAZOLE REVERSED AMIDES AND DERIVATIVES AS SELECTIVE GLUCOCORTICOID RECEPTOR MODULATORS |
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