MEP10408A - Platinum derivative pharmaceutical formulations - Google Patents

Platinum derivative pharmaceutical formulations

Info

Publication number
MEP10408A
MEP10408A MEP-104/08A MEP10408A MEP10408A ME P10408 A MEP10408 A ME P10408A ME P10408 A MEP10408 A ME P10408A ME P10408 A MEP10408 A ME P10408A
Authority
ME
Montenegro
Prior art keywords
pharmaceutical formulations
platinum derivative
derivative pharmaceutical
pharmaceutically acceptable
present
Prior art date
Application number
MEP-104/08A
Other languages
Bosnian (bs)
English (en)
Croatian (hr)
Inventor
Sara Lauria
Alessandro Martini
Cristina Ciocca
Original Assignee
Pharmacia Italia Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21744006&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MEP10408(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia Italia Spa filed Critical Pharmacia Italia Spa
Publication of MEP10408A publication Critical patent/MEP10408A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
MEP-104/08A 2001-12-06 2002-11-22 Platinum derivative pharmaceutical formulations MEP10408A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10/010,122 US6476068B1 (en) 2001-12-06 2001-12-06 Platinum derivative pharmaceutical formulations
PCT/EP2002/013146 WO2003047587A1 (en) 2001-12-06 2002-11-22 Platinum derivative pharmaceutical formulations

Publications (1)

Publication Number Publication Date
MEP10408A true MEP10408A (en) 2011-02-10

Family

ID=21744006

Family Applications (1)

Application Number Title Priority Date Filing Date
MEP-104/08A MEP10408A (en) 2001-12-06 2002-11-22 Platinum derivative pharmaceutical formulations

Country Status (42)

Country Link
US (3) US6476068B1 (no)
EP (1) EP1453517B1 (no)
JP (1) JP2005515202A (no)
KR (1) KR100941210B1 (no)
CN (1) CN100540006C (no)
AP (1) AP1760A (no)
AR (1) AR037629A1 (no)
AT (1) ATE317260T1 (no)
AU (1) AU2002352105B2 (no)
BR (1) BR0214757A (no)
CA (1) CA2468916C (no)
CO (1) CO5580776A2 (no)
CR (1) CR7362A (no)
CY (1) CY1105608T1 (no)
DE (1) DE60209145T2 (no)
DK (1) DK1453517T3 (no)
EA (1) EA008090B1 (no)
EC (1) ECSP045140A (no)
ES (1) ES2258661T3 (no)
GE (1) GEP20063895B (no)
HK (1) HK1072002A1 (no)
HR (1) HRP20040514A2 (no)
HU (1) HUP0402217A3 (no)
IL (2) IL162348A0 (no)
IS (1) IS2580B (no)
MA (1) MA27153A1 (no)
ME (1) MEP10408A (no)
MX (1) MXPA04005423A (no)
MY (1) MY134422A (no)
NO (1) NO330159B1 (no)
NZ (1) NZ533383A (no)
OA (1) OA12739A (no)
PL (1) PL206755B1 (no)
PT (1) PT1453517E (no)
RO (1) RO121509B1 (no)
RS (1) RS50360B (no)
SI (1) SI21493A (no)
TN (1) TNSN04104A1 (no)
TW (1) TW200409640A (no)
UA (1) UA77728C2 (no)
WO (1) WO2003047587A1 (no)
ZA (1) ZA200404525B (no)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040186172A1 (en) * 2001-07-02 2004-09-23 Houssam Ibrahim Oxaliplatin active substance with a very low content of oxalic acid
CA2388352A1 (en) * 2002-05-31 2003-11-30 Voiceage Corporation A method and device for frequency-selective pitch enhancement of synthesized speed
US20040022842A1 (en) * 2002-06-03 2004-02-05 Mebiopharm Co., Ltd. Liposome preparations containing oxaliplatin
DE10314377A1 (de) * 2003-03-28 2004-10-07 Stada Arzneimittel Ag Gebrauchsfertige Oxaliplatin-Lösungen
WO2005020980A1 (en) * 2003-08-28 2005-03-10 Mayne Pharma Pty Ltd Acid containing oxaliplatin formulations
GB2441445B (en) * 2003-08-28 2008-04-23 Mayne Pharma Ltd Acid containing oxaliplatin formulation
EP1682529A4 (en) * 2003-11-07 2010-06-30 Novartis Vaccines & Diagnostic METHODS FOR SYNTHESIS OF QUINOLINONE COMPOUNDS
US7795205B2 (en) * 2004-04-12 2010-09-14 Canyon Pharmaceuticals, Inc. Methods for effecting regression of tumor mass and size in a metastasized pancreatic tumor
MXPA06014477A (es) * 2004-06-09 2007-03-21 Taiho Pharmaceutical Co Ltd Agente antitumor, fortificador de efecto antitumor y metodo de terapia para cancer.
US7208616B2 (en) * 2004-07-12 2007-04-24 Sicor, Inc. Cis-diiodo-(trans-L-1,2-cyclohexanediamine) platinum (II) complex and processes for preparing high purity oxaliplatin
US20060063720A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Oxaliplatin solution concentrate
US20060063833A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Ready-to-use oxaliplatin solutions
DE102004052877B4 (de) * 2004-11-02 2008-06-19 Ebewe Pharma Ges.M.B.H. Nfg.Kg Stabile wässrige Formulierungen eines Platin-Derivats
CN1311818C (zh) * 2004-11-22 2007-04-25 山东蓝金生物工程有限公司 一种抗实体肿瘤的药物组合物
DE102004063764A1 (de) * 2004-12-29 2006-07-13 Hexal Ag Kunststoff-Flasche für Oxaliplatin
JP2006248978A (ja) 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
ATE430564T1 (de) * 2005-03-28 2009-05-15 Dabur Pharma Ltd Stabile pharmazeutische zusammensetzungen aus antitumoralen platin-(ii)-mitteln
DK1885187T3 (da) * 2005-05-13 2013-12-09 Novartis Ag Fremgangsmåde til behandling af lægemiddelresistent cancer
DE102005038347A1 (de) * 2005-08-11 2007-02-15 Hexal Ag Herstellung einer Oxaliplatin-Lösung und Behälter sowie Behälter-Set mit der Lösung
WO2007029268A2 (en) * 2005-09-05 2007-03-15 Dabur Pharma Limited Stable oxaliplatin formulation
AR062545A1 (es) * 2005-11-29 2008-11-19 Novartis Ag Formulaciones estables de quinolinonas
US20090076139A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched oxalplatin
WO2009087660A1 (en) 2007-11-12 2009-07-16 Intas Pharmaceuticals Limited Stable oxaliplatin composition for parenteral administration
CA2715832A1 (en) * 2008-02-29 2009-09-11 Eagle Pharmaceuticals, Inc. Topotecan ready to use solutions
WO2010056847A2 (en) * 2008-11-13 2010-05-20 Taigen Biotechnology Co., Ltd. Lyophilization formulation
KR101396461B1 (ko) 2009-09-21 2014-05-20 (주)바이오시네틱스 옥살리플라틴의 나노 입자 및 이를 제조하는 방법
WO2012006101A2 (en) 2010-06-28 2012-01-12 The General Hospital Corporation Blood substitutes and uses thereof
CN102274171A (zh) * 2011-08-04 2011-12-14 上海希迪制药有限公司 一种奥沙利铂注射剂
EP2874606B1 (en) 2012-07-18 2019-03-06 Onyx Therapeutics, Inc. Liposomal compositions of epoxyketone-based proteasome inhibitors
JP5929607B2 (ja) * 2012-08-06 2016-06-08 ニプロ株式会社 オキサリプラチン製剤
CN102885765B (zh) * 2012-10-25 2013-11-06 哈药集团生物工程有限公司 一种盐酸伊立替康注射液及其制备方法
US10098813B2 (en) 2014-09-03 2018-10-16 Sun Pharmaceutical Industries Limited Perfusion dosage form
KR101683635B1 (ko) * 2014-12-29 2016-12-09 가천대학교 산학협력단 락테이트 금속염을 포함하는 암 치료용 약학 조성물
KR102293907B1 (ko) * 2015-06-30 2021-08-26 한미약품 주식회사 이리노테칸 함유 경구용 고형제제 및 그 제조방법
EP3413862B8 (en) 2016-02-09 2024-03-13 Sun Pharmaceutical Industries Ltd. Perfusion system
EP3538546A1 (en) 2016-11-14 2019-09-18 Novartis AG Compositions, methods, and therapeutic uses related to fusogenic protein minion
CA3087953A1 (en) 2018-01-12 2019-07-18 Metimedi Pharmaceuticals Co., Ltd. Methods of treating chronic inflammatory diseases
KR101998246B1 (ko) 2018-08-22 2019-07-10 주식회사 메타파인즈 금속이온에 결합된 이온화합물을 포함하는 암 치료용 약학 조성물

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6041077B2 (ja) 1976-09-06 1985-09-13 喜徳 喜谷 １，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体
US5041578A (en) * 1988-11-22 1991-08-20 Board Of Regents, The University Of Texas System Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as antitumor agents
DE69233169T2 (de) 1991-11-15 2004-05-27 Smithkline Beecham Corp. Cisplatin und Topotecan enthaltende Zusammensetzung als antitumor.
JPH0776230B2 (ja) 1992-01-13 1995-08-16 田中貴金属工業株式会社 白金化合物の製造方法
JP2673331B2 (ja) 1993-01-12 1997-11-05 田中貴金属工業 株式会社 光学的に高純度なシス―オキザラート（トランス―１―１，２―シクロヘキサンジアミン）白金（▲ｉｉ▼）
JPH06287021A (ja) 1992-04-22 1994-10-11 Tanaka Kikinzoku Kogyo Kk 光学活性な白金錯化合物の光学的分割方法
WO1994012193A1 (fr) 1992-11-24 1994-06-09 Debiopharm S.A. Combinaison de cisplatine avec l'oxaliplatine
DE69320206T2 (de) * 1992-11-27 1999-02-11 Napro Biotherapeutics Inc Paclitaxel enthaltende injizierbare zusammensetzung
JP3025602B2 (ja) 1993-05-21 2000-03-27 デビオファーム エス．アー． 光学的に高純度なシス−オキザラート（トランス−ｌ−１，２−シクロヘキサンジアミン）白金（ＩＩ）錯体の製造方法
US5455270A (en) * 1993-08-11 1995-10-03 Bristol-Myers Squibb Co. Stabilized solutions of platinum(II) antitumor agents
BR9508554A (pt) 1994-08-08 1997-11-25 Debiopharm Sa Preparação farmaceuticamente estável de oxaliplatina
DE69531722T2 (de) 1994-11-11 2004-07-01 Debiopharm S.A. Karzinostatische Zusammensetzungen, welche Cis-Oxaliplatin und eine oder mehrere andere verträgliche Karzinostatika enthalten
US5919816A (en) 1994-11-14 1999-07-06 Bionumerik Pharmaceuticals, Inc. Formulations and methods of reducing toxicity of antineoplastic agents
EP0812852B1 (en) * 1995-02-28 2003-04-23 Yoshinori Kidani Novel platinum (iv) complexes, process for producing the same, and carcinostatic agents containing the same
US5776959A (en) 1995-06-05 1998-07-07 Washington University Anticonvulsant and anxiolytic lactam and thiolactam derivatives
DE69713763T2 (de) * 1996-03-11 2003-03-13 Yoshinori Kidani Binukleare platinkomplexe, verfahren zu ihrer herstellung und pharmazeutische zusammensetzungen die diese komplexe enthalten
JP3154399B2 (ja) 1996-07-04 2001-04-09 デビオファーム エス．アー． 白金化合物の製造方法
DE69725747T2 (de) 1996-08-23 2004-07-29 Sequus Pharmaceuticals, Inc., Menlo Park Liposome enthaltend cisplatin
US6056973A (en) 1996-10-11 2000-05-02 Sequus Pharmaceuticals, Inc. Therapeutic liposome composition and method of preparation
IL131008A (en) 1997-02-05 2003-06-24 Upjohn Co Lipid complexes and liposomes of highly insoluble platinum complex dicarboxylate
EP1014990B1 (en) 1997-03-07 2006-09-06 Sanofi-Aventis U.S. LLC Antitumor combination of 3-amino-1,2,4-benzotriazine 1,4-dioxide/paclitaxel/platinum
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
GB9804013D0 (en) * 1998-02-25 1998-04-22 Sanofi Sa Formulations
DK1121117T3 (da) 1998-10-14 2002-09-16 Debiopharm Sa Indpakning af et oxaliplatinholdigt præparat
WO2001015691A1 (fr) 1999-08-30 2001-03-08 Debiopharm S.A. Preparation pharmaceutique stable d'oxaliplatine pour administration par voie parenterale
AU2001240001A1 (en) 2000-03-08 2001-09-17 Bristol-Myers Squibb Company Oral dosage form for administration of the combination of tegafur, uracil, folinic acid, and oxaliplatin and method of using the same
SE0003026D0 (sv) * 2000-08-25 2000-08-25 Kerstin Sunnerheim Use for conifer sapling protection

Also Published As

Publication number Publication date
US20030109515A1 (en) 2003-06-12
CN1612737A (zh) 2005-05-04
JP2005515202A (ja) 2005-05-26
HK1072002A1 (en) 2005-08-12
HUP0402217A3 (en) 2005-11-28
MXPA04005423A (es) 2004-10-11
YU59704A (sh) 2006-08-17
AP1760A (en) 2007-07-18
BR0214757A (pt) 2004-09-14
PT1453517E (pt) 2006-06-30
CY1105608T1 (el) 2010-12-22
IS2580B (is) 2010-02-15
AP2004003055A0 (en) 2004-06-30
US6476068B1 (en) 2002-11-05
US6673805B2 (en) 2004-01-06
AR037629A1 (es) 2004-11-17
AU2002352105B2 (en) 2009-12-03
EA200400777A1 (ru) 2004-12-30
IL162348A0 (en) 2005-11-20
ECSP045140A (es) 2004-08-27
PL206755B1 (pl) 2010-09-30
RS50360B (sr) 2009-11-10
EP1453517B1 (en) 2006-02-08
ATE317260T1 (de) 2006-02-15
OA12739A (en) 2006-06-30
UA77728C2 (en) 2007-01-15
TW200409640A (en) 2004-06-16
KR100941210B1 (ko) 2010-02-10
NO20042842L (no) 2004-07-05
US20030109514A1 (en) 2003-06-12
EA008090B1 (ru) 2007-02-27
RO121509B1 (ro) 2007-10-30
SI21493A (sl) 2004-12-31
NO330159B1 (no) 2011-02-28
ZA200404525B (en) 2005-08-15
MA27153A1 (fr) 2005-01-03
DK1453517T3 (da) 2006-06-19
EP1453517A1 (en) 2004-09-08
NZ533383A (en) 2007-02-23
CA2468916C (en) 2009-01-20
DE60209145T2 (de) 2006-10-26
GEP20063895B (en) 2006-08-10
CR7362A (es) 2009-02-12
DE60209145D1 (de) 2006-04-20
PL370254A1 (en) 2005-05-16
CA2468916A1 (en) 2003-06-12
HUP0402217A2 (hu) 2005-01-28
CO5580776A2 (es) 2005-11-30
TNSN04104A1 (fr) 2006-06-01
HRP20040514A2 (en) 2004-10-31
AU2002352105A1 (en) 2003-06-17
CN100540006C (zh) 2009-09-16
KR20050058278A (ko) 2005-06-16
MY134422A (en) 2007-12-31
IL162348A (en) 2010-11-30
IS7298A (is) 2004-06-03
ES2258661T3 (es) 2006-09-01
WO2003047587A1 (en) 2003-06-12

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