DE60209145D1 - Pharmazeutische formulierungen mit platinderivaten - Google Patents

Pharmazeutische formulierungen mit platinderivaten

Info

Publication number
DE60209145D1
DE60209145D1 DE60209145T DE60209145T DE60209145D1 DE 60209145 D1 DE60209145 D1 DE 60209145D1 DE 60209145 T DE60209145 T DE 60209145T DE 60209145 T DE60209145 T DE 60209145T DE 60209145 D1 DE60209145 D1 DE 60209145D1
Authority
DE
Germany
Prior art keywords
pharmaceutical formulations
platin derivatives
platin
derivatives
formulations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60209145T
Other languages
English (en)
Other versions
DE60209145T2 (de
Inventor
Sara Lauria
Alessandro Martini
Cristina Ciocca
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nerviano Medical Sciences SRL
Original Assignee
Pharmacia Italia SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21744006&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60209145(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Pharmacia Italia SpA filed Critical Pharmacia Italia SpA
Application granted granted Critical
Publication of DE60209145D1 publication Critical patent/DE60209145D1/de
Publication of DE60209145T2 publication Critical patent/DE60209145T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47Quinolines; Isoquinolines
    • A61K31/4738Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4745Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/555Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
DE60209145T 2001-12-06 2002-11-22 Pharmazeutische formulierungen mit platinderivaten Expired - Lifetime DE60209145T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US10/010,122 US6476068B1 (en) 2001-12-06 2001-12-06 Platinum derivative pharmaceutical formulations
US10122 2001-12-06
PCT/EP2002/013146 WO2003047587A1 (en) 2001-12-06 2002-11-22 Platinum derivative pharmaceutical formulations

Publications (2)

Publication Number Publication Date
DE60209145D1 true DE60209145D1 (de) 2006-04-20
DE60209145T2 DE60209145T2 (de) 2006-10-26

Family

ID=21744006

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60209145T Expired - Lifetime DE60209145T2 (de) 2001-12-06 2002-11-22 Pharmazeutische formulierungen mit platinderivaten

Country Status (42)

Country Link
US (3) US6476068B1 (de)
EP (1) EP1453517B1 (de)
JP (1) JP2005515202A (de)
KR (1) KR100941210B1 (de)
CN (1) CN100540006C (de)
AP (1) AP1760A (de)
AR (1) AR037629A1 (de)
AT (1) ATE317260T1 (de)
AU (1) AU2002352105B2 (de)
BR (1) BR0214757A (de)
CA (1) CA2468916C (de)
CO (1) CO5580776A2 (de)
CR (1) CR7362A (de)
CY (1) CY1105608T1 (de)
DE (1) DE60209145T2 (de)
DK (1) DK1453517T3 (de)
EA (1) EA008090B1 (de)
EC (1) ECSP045140A (de)
ES (1) ES2258661T3 (de)
GE (1) GEP20063895B (de)
HK (1) HK1072002A1 (de)
HR (1) HRP20040514A2 (de)
HU (1) HUP0402217A3 (de)
IL (2) IL162348A0 (de)
IS (1) IS2580B (de)
MA (1) MA27153A1 (de)
ME (1) MEP10408A (de)
MX (1) MXPA04005423A (de)
MY (1) MY134422A (de)
NO (1) NO330159B1 (de)
NZ (1) NZ533383A (de)
OA (1) OA12739A (de)
PL (1) PL206755B1 (de)
PT (1) PT1453517E (de)
RO (1) RO121509B1 (de)
RS (1) RS50360B (de)
SI (1) SI21493A (de)
TN (1) TNSN04104A1 (de)
TW (1) TW200409640A (de)
UA (1) UA77728C2 (de)
WO (1) WO2003047587A1 (de)
ZA (1) ZA200404525B (de)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1404689A1 (de) * 2001-07-02 2004-04-07 Debiopharm S.A. Aktive oxiplatinverbindung mit sehr niedrigem oxalsaüregehalt
CA2388352A1 (en) * 2002-05-31 2003-11-30 Voiceage Corporation A method and device for frequency-selective pitch enhancement of synthesized speed
US20040022842A1 (en) * 2002-06-03 2004-02-05 Mebiopharm Co., Ltd. Liposome preparations containing oxaliplatin
DE10314377A1 (de) * 2003-03-28 2004-10-07 Stada Arzneimittel Ag Gebrauchsfertige Oxaliplatin-Lösungen
GB2421911A (en) * 2003-08-28 2006-07-12 Mayne Pharma Pty Ltd Acid containing oxaliplatin formulations
GB2441445B (en) * 2003-08-28 2008-04-23 Mayne Pharma Ltd Acid containing oxaliplatin formulation
BRPI0416143A (pt) * 2003-11-07 2007-01-02 Chiron Corp sais farmaceuticamente aceitáveis de compostos de quinolinona tendo propriedades farmacêuticas aperfeiçoadas
US7795205B2 (en) * 2004-04-12 2010-09-14 Canyon Pharmaceuticals, Inc. Methods for effecting regression of tumor mass and size in a metastasized pancreatic tumor
MXPA06014477A (es) * 2004-06-09 2007-03-21 Taiho Pharmaceutical Co Ltd Agente antitumor, fortificador de efecto antitumor y metodo de terapia para cancer.
US7208616B2 (en) * 2004-07-12 2007-04-24 Sicor, Inc. Cis-diiodo-(trans-L-1,2-cyclohexanediamine) platinum (II) complex and processes for preparing high purity oxaliplatin
US20060063833A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Ready-to-use oxaliplatin solutions
US20060063720A1 (en) * 2004-09-22 2006-03-23 Edgar Schridde Oxaliplatin solution concentrate
DE102004052877B4 (de) * 2004-11-02 2008-06-19 Ebewe Pharma Ges.M.B.H. Nfg.Kg Stabile wässrige Formulierungen eines Platin-Derivats
CN1311818C (zh) * 2004-11-22 2007-04-25 山东蓝金生物工程有限公司 一种抗实体肿瘤的药物组合物
DE102004063764A1 (de) * 2004-12-29 2006-07-13 Hexal Ag Kunststoff-Flasche für Oxaliplatin
JP2006248978A (ja) 2005-03-10 2006-09-21 Mebiopharm Co Ltd 新規なリポソーム製剤
EP1879568B1 (de) * 2005-03-28 2009-05-06 Dabur Pharma Limited Stabile pharmazeutische zusammensetzungen aus antitumoralen platin-(ii)-mitteln
MX2007014206A (es) * 2005-05-13 2008-02-07 Novartis Ag Metodos para tratar cancer resistente a los farmacos.
DE102005038347A1 (de) * 2005-08-11 2007-02-15 Hexal Ag Herstellung einer Oxaliplatin-Lösung und Behälter sowie Behälter-Set mit der Lösung
WO2007029268A2 (en) * 2005-09-05 2007-03-15 Dabur Pharma Limited Stable oxaliplatin formulation
RU2433826C2 (ru) * 2005-11-29 2011-11-20 Новартис Аг Композиции хинолинонов
US20090076139A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched oxalplatin
WO2009087660A1 (en) 2007-11-12 2009-07-16 Intas Pharmaceuticals Limited Stable oxaliplatin composition for parenteral administration
MX2010009453A (es) * 2008-02-29 2011-03-01 Eagle Pharmaceuticals Inc Soluciones de topotecano listas para utilizarse.
TW201021855A (en) * 2008-11-13 2010-06-16 Taigen Biotechnology Co Ltd Lyophilization formulation
JP5759464B2 (ja) 2009-09-21 2015-08-05 ジェイダブリュー ファーマシューティカル コーポレイション オキサリプラチンのナノ粒子及びその製造方法
WO2012006101A2 (en) 2010-06-28 2012-01-12 The General Hospital Corporation Blood substitutes and uses thereof
CN102274171A (zh) * 2011-08-04 2011-12-14 上海希迪制药有限公司 一种奥沙利铂注射剂
AU2013292636A1 (en) 2012-07-18 2015-02-05 Onyx Therapeutics, Inc. Liposomal compositions of epoxyketone-based proteasome inhibitors
JP5929607B2 (ja) * 2012-08-06 2016-06-08 ニプロ株式会社 オキサリプラチン製剤
CN102885765B (zh) * 2012-10-25 2013-11-06 哈药集团生物工程有限公司 一种盐酸伊立替康注射液及其制备方法
US10098813B2 (en) * 2014-09-03 2018-10-16 Sun Pharmaceutical Industries Limited Perfusion dosage form
KR101683635B1 (ko) * 2014-12-29 2016-12-09 가천대학교 산학협력단 락테이트 금속염을 포함하는 암 치료용 약학 조성물
KR102293907B1 (ko) * 2015-06-30 2021-08-26 한미약품 주식회사 이리노테칸 함유 경구용 고형제제 및 그 제조방법
PL3413862T3 (pl) 2016-02-09 2024-03-18 Sun Pharmaceutical Industries Ltd. Układ perfuzyjny
US11339209B2 (en) 2016-11-14 2022-05-24 Novartis Ag Compositions, methods, and therapeutic uses related to fusogenic protein minion
JP7290870B2 (ja) 2018-01-12 2023-06-14 メティメディ ファーマシューティカルズ カンパニー リミテッド 慢性炎症性疾患を処置する方法
KR101998246B1 (ko) 2018-08-22 2019-07-10 주식회사 메타파인즈 금속이온에 결합된 이온화합물을 포함하는 암 치료용 약학 조성물

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6041077B2 (ja) 1976-09-06 1985-09-13 喜徳 喜谷 1,2‐ジアミノシクロヘキサン異性体のシス白金(2)錯体
US5041578A (en) * 1988-11-22 1991-08-20 Board Of Regents, The University Of Texas System Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as antitumor agents
CA2123321C (en) 1991-11-15 2003-09-30 Randall Keith Johnson Combination chemotherapy
JPH0776230B2 (ja) 1992-01-13 1995-08-16 田中貴金属工業株式会社 白金化合物の製造方法
JP2673331B2 (ja) 1993-01-12 1997-11-05 田中貴金属工業 株式会社 光学的に高純度なシス―オキザラート(トランス―1―1,2―シクロヘキサンジアミン)白金(▲ii▼)
JPH06287021A (ja) 1992-04-22 1994-10-11 Tanaka Kikinzoku Kogyo Kk 光学活性な白金錯化合物の光学的分割方法
WO1994012193A1 (fr) 1992-11-24 1994-06-09 Debiopharm S.A. Combinaison de cisplatine avec l'oxaliplatine
DK0835657T3 (da) * 1992-11-27 2005-01-10 Mayne Pharma Usa Inc Stabil, injicerbar paclitaxelsammensætning
JP3025602B2 (ja) 1993-05-21 2000-03-27 デビオファーム エス.アー. 光学的に高純度なシス−オキザラート(トランス−l−1,2−シクロヘキサンジアミン)白金(II)錯体の製造方法
US5455270A (en) * 1993-08-11 1995-10-03 Bristol-Myers Squibb Co. Stabilized solutions of platinum(II) antitumor agents
DE69519300T2 (de) 1994-08-08 2001-05-31 Debiopharm Sa Stabiles arzneimittel enthaltend oxaliplatin
DE69531722T2 (de) 1994-11-11 2004-07-01 Debiopharm S.A. Karzinostatische Zusammensetzungen, welche Cis-Oxaliplatin und eine oder mehrere andere verträgliche Karzinostatika enthalten
US5919816A (en) 1994-11-14 1999-07-06 Bionumerik Pharmaceuticals, Inc. Formulations and methods of reducing toxicity of antineoplastic agents
AU4842996A (en) * 1995-02-28 1996-09-18 Yoshinori Kidani Novel platinum (iv) complexes, process for producing the same, and carcinostatic agents containing the same
US5776959A (en) 1995-06-05 1998-07-07 Washington University Anticonvulsant and anxiolytic lactam and thiolactam derivatives
US6153646A (en) * 1996-03-11 2000-11-28 Yoshinori Kidani Binuclear platinum complexes, method for preparing same and pharmaceutical compositions containing said complexes
JP3154399B2 (ja) 1996-07-04 2001-04-09 デビオファーム エス.アー. 白金化合物の製造方法
WO1998007409A1 (en) 1996-08-23 1998-02-26 Sequus Pharmaceuticals, Inc. Liposomes containing a cisplatin compound
US6056973A (en) 1996-10-11 2000-05-02 Sequus Pharmaceuticals, Inc. Therapeutic liposome composition and method of preparation
UA71540C2 (uk) 1997-02-05 2004-12-15 Фармація Енд Апджон Компані Спосіб одержання ліпідних комплексів або ліпосом водонерозчинного діаміноциклогексанкарбоксилату платини та фармацевтична композиція, що містить ліпідний комплекс або ліпосоми водонерозчинного діаміноциклогексанкарбоксилату платини
EP1014990B1 (de) 1997-03-07 2006-09-06 Sanofi-Aventis U.S. LLC Antitumorkombination aus 3-amino-1,2,4-benzotriazine 1,4-dioxid/paclitaxel/platin
GB9727523D0 (en) 1997-12-31 1998-02-25 Pharmacia & Upjohn Spa Alpha-aminoamide derivatives useful as analgesic agents
GB9804013D0 (en) * 1998-02-25 1998-04-22 Sanofi Sa Formulations
PT1121117E (pt) 1998-10-14 2002-10-31 Debiopharm Sa Acondicionamento de uma preparacao de oxaliplatina
CA2382389C (fr) 1999-08-30 2010-06-29 Debiopharm S.A. Preparation pharmaceutique stable d'oxaliplatine pour administration par voie parenterale
WO2001066102A2 (en) 2000-03-08 2001-09-13 Bristol-Myers Squibb Company Oral dosage form for administration of the combination of tegafur, uracil, folinic acid, and oxaliplatin and method of using the same
SE0003026D0 (sv) * 2000-08-25 2000-08-25 Kerstin Sunnerheim Use for conifer sapling protection

Also Published As

Publication number Publication date
EP1453517A1 (de) 2004-09-08
ES2258661T3 (es) 2006-09-01
DE60209145T2 (de) 2006-10-26
CN100540006C (zh) 2009-09-16
TNSN04104A1 (fr) 2006-06-01
IS2580B (is) 2010-02-15
AP2004003055A0 (en) 2004-06-30
CA2468916C (en) 2009-01-20
DK1453517T3 (da) 2006-06-19
JP2005515202A (ja) 2005-05-26
WO2003047587A1 (en) 2003-06-12
CO5580776A2 (es) 2005-11-30
HUP0402217A2 (hu) 2005-01-28
IL162348A0 (en) 2005-11-20
CA2468916A1 (en) 2003-06-12
KR100941210B1 (ko) 2010-02-10
BR0214757A (pt) 2004-09-14
CY1105608T1 (el) 2010-12-22
NO20042842L (no) 2004-07-05
AU2002352105A1 (en) 2003-06-17
ECSP045140A (es) 2004-08-27
HRP20040514A2 (en) 2004-10-31
US20030109514A1 (en) 2003-06-12
AR037629A1 (es) 2004-11-17
PT1453517E (pt) 2006-06-30
CR7362A (es) 2009-02-12
IL162348A (en) 2010-11-30
HUP0402217A3 (en) 2005-11-28
ZA200404525B (en) 2005-08-15
US6673805B2 (en) 2004-01-06
PL370254A1 (en) 2005-05-16
GEP20063895B (en) 2006-08-10
UA77728C2 (en) 2007-01-15
RO121509B1 (ro) 2007-10-30
SI21493A (sl) 2004-12-31
EP1453517B1 (de) 2006-02-08
MY134422A (en) 2007-12-31
NO330159B1 (no) 2011-02-28
AU2002352105B2 (en) 2009-12-03
AP1760A (en) 2007-07-18
US6476068B1 (en) 2002-11-05
KR20050058278A (ko) 2005-06-16
MA27153A1 (fr) 2005-01-03
TW200409640A (en) 2004-06-16
PL206755B1 (pl) 2010-09-30
NZ533383A (en) 2007-02-23
EA008090B1 (ru) 2007-02-27
ATE317260T1 (de) 2006-02-15
MXPA04005423A (es) 2004-10-11
MEP10408A (en) 2011-02-10
OA12739A (en) 2006-06-30
YU59704A (sh) 2006-08-17
EA200400777A1 (ru) 2004-12-30
HK1072002A1 (en) 2005-08-12
IS7298A (is) 2004-06-03
CN1612737A (zh) 2005-05-04
US20030109515A1 (en) 2003-06-12
RS50360B (sr) 2009-11-10

Similar Documents

Publication Publication Date Title
DE60209145D1 (de) Pharmazeutische formulierungen mit platinderivaten
DE60118008D1 (de) Pharmazeutische zusammensetzungen mit amlodipinmaleat
ATE307571T1 (de) Pharmazeutische formulierung enthaltend bicalutamid
DE60142197D1 (de) Pharmazeutische Zusammensetzung
DE60316323D1 (de) Feste pharmazeutische formulierungen mit telmisartan
NO20033384D0 (no) Farmasöytisk formulering
DE60111769D1 (de) Flüssige pharmazeutische formulierungen mit verbesserter oraler veträglichkeit
ITTO20010008A0 (it) Formulazione farmaceutica
DE60332393D1 (de) Flüssige pharmazeutische zusammensetzung mit pyridonderivaten
DK1204410T3 (da) Farmaceutisk doseringsform med flere komponenter
NO20032909L (no) Glukopyranosyloksypyrazolderivater samt medikamentell anvendelse derav
ATE404180T1 (de) Geschmacksmaskierte pharmazeutische partikel
NO20030627D0 (no) Hydrogel-drevet medikament doseringsform
ATE334656T1 (de) Flüssige pharmazeutische zusammensetzung
DE60210139D1 (de) Pharmazeutische zusammensetzungen enthaltend tegaserod
NO20035627D0 (no) Farmasöytisk formulering
ATE327759T1 (de) Pharmazeutische zusammensetzung mit verlungerter freisetzung
DE60217390D1 (de) Bicalutamid enthaltende pharmazeutische zusammensetzung
ATE366128T1 (de) Pharmazeutische zusammensetzung
DE60336999D1 (de) Melatonin enthaltende pharmazeutische formulierung
DE60310526D1 (de) Ivabradin enthaltende pharmazeutische zusammensetzung mit oraler dispersion
ATE412405T1 (de) Pharmazeutische zusammensetzung mit modifiziertem träger
DE10291905D2 (de) Pharmazeutische Zusammensetzung
ATE350029T1 (de) Pharmazeutische zusammensetzung enthaltend gamma- butyrobetain
EE200300466A (et) Püridoindolooni derivaatide kasutamine ravimite valmistamiseks

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: NERVIANO MEDICAL SCIENCES S.R.L., NERVIANO, MI, IT