MA27153A1 - Formulations pharmaceutiques de derives de platine - Google Patents
Formulations pharmaceutiques de derives de platineInfo
- Publication number
- MA27153A1 MA27153A1 MA27715A MA27715A MA27153A1 MA 27153 A1 MA27153 A1 MA 27153A1 MA 27715 A MA27715 A MA 27715A MA 27715 A MA27715 A MA 27715A MA 27153 A1 MA27153 A1 MA 27153A1
- Authority
- MA
- Morocco
- Prior art keywords
- formulations
- pharmaceutical formulations
- platinum derivatives
- pharmaceutically acceptable
- present
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/555—Heterocyclic compounds containing heavy metals, e.g. hemin, hematin, melarsoprol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Oncology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
DEPOSANT Société dite: PHARMACIA ITALIA S.P.A. REVENDICATION DE PRIORITES US 6 Décembre 2001 10/010,122 Voir en annexe le titre de l'invention et le texte de l'abrégé Formulations pharmaceutiques de dérivés de platine La présente invention concerne des formulations de solutions stables nouvelles comprenant de l'oxaliplatine, une quantité stabilisante efficace d'acide lactique et/ou d'un de ses sels pharmaceutiquement acceptables et un support pharmaceutiquement acceptable. Un procédé pour la production de telles formulations prêtes à l'administration et une méthode pour leur utilisation en thérapie antitumorale sont également inclus dans le cadre de la présente invention.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/010,122 US6476068B1 (en) | 2001-12-06 | 2001-12-06 | Platinum derivative pharmaceutical formulations |
Publications (1)
Publication Number | Publication Date |
---|---|
MA27153A1 true MA27153A1 (fr) | 2005-01-03 |
Family
ID=21744006
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA27715A MA27153A1 (fr) | 2001-12-06 | 2004-06-04 | Formulations pharmaceutiques de derives de platine |
Country Status (42)
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1404689A1 (fr) * | 2001-07-02 | 2004-04-07 | Debiopharm S.A. | Substance active a base d'oxaliplatine presentant une faible teneur en acide oxalique |
CA2388352A1 (fr) * | 2002-05-31 | 2003-11-30 | Voiceage Corporation | Methode et dispositif pour l'amelioration selective en frequence de la hauteur de la parole synthetisee |
US20040022842A1 (en) * | 2002-06-03 | 2004-02-05 | Mebiopharm Co., Ltd. | Liposome preparations containing oxaliplatin |
DE10314377A1 (de) * | 2003-03-28 | 2004-10-07 | Stada Arzneimittel Ag | Gebrauchsfertige Oxaliplatin-Lösungen |
GB2441445B (en) * | 2003-08-28 | 2008-04-23 | Mayne Pharma Ltd | Acid containing oxaliplatin formulation |
NZ545591A (en) * | 2003-08-28 | 2008-11-28 | Mayne Pharma Ltd | Acid containing oxaliplatin formulations |
CA2543820C (fr) * | 2003-11-07 | 2012-07-10 | Chiron Corporation | Methodes de synthese de composes de quinolinone |
US7795205B2 (en) * | 2004-04-12 | 2010-09-14 | Canyon Pharmaceuticals, Inc. | Methods for effecting regression of tumor mass and size in a metastasized pancreatic tumor |
RS52668B (en) * | 2004-06-09 | 2013-06-28 | Taiho Pharmaceutical Co. Ltd. | ANTITUMOR EFFECT, ANTI-TUMOR AND ANALYSIS PROCESS |
US7208616B2 (en) * | 2004-07-12 | 2007-04-24 | Sicor, Inc. | Cis-diiodo-(trans-L-1,2-cyclohexanediamine) platinum (II) complex and processes for preparing high purity oxaliplatin |
US20060063720A1 (en) * | 2004-09-22 | 2006-03-23 | Edgar Schridde | Oxaliplatin solution concentrate |
US20060063833A1 (en) * | 2004-09-22 | 2006-03-23 | Edgar Schridde | Ready-to-use oxaliplatin solutions |
DE102004052877B4 (de) * | 2004-11-02 | 2008-06-19 | Ebewe Pharma Ges.M.B.H. Nfg.Kg | Stabile wässrige Formulierungen eines Platin-Derivats |
CN1311818C (zh) * | 2004-11-22 | 2007-04-25 | 山东蓝金生物工程有限公司 | 一种抗实体肿瘤的药物组合物 |
DE102004063764A1 (de) * | 2004-12-29 | 2006-07-13 | Hexal Ag | Kunststoff-Flasche für Oxaliplatin |
JP2006248978A (ja) | 2005-03-10 | 2006-09-21 | Mebiopharm Co Ltd | 新規なリポソーム製剤 |
ATE430564T1 (de) * | 2005-03-28 | 2009-05-15 | Dabur Pharma Ltd | Stabile pharmazeutische zusammensetzungen aus antitumoralen platin-(ii)-mitteln |
KR101319122B1 (ko) * | 2005-05-13 | 2013-10-23 | 노파르티스 아게 | 약물 저항성 암을 치료하는 방법 |
DE102005038347A1 (de) * | 2005-08-11 | 2007-02-15 | Hexal Ag | Herstellung einer Oxaliplatin-Lösung und Behälter sowie Behälter-Set mit der Lösung |
WO2007029268A2 (fr) * | 2005-09-05 | 2007-03-15 | Dabur Pharma Limited | Formulation stable d'oxaliplatine |
PL1957074T3 (pl) * | 2005-11-29 | 2014-08-29 | Novartis Ag | Preparaty chinolinonów |
US20090076139A1 (en) * | 2007-09-19 | 2009-03-19 | Protia, Llc | Deuterium-enriched oxalplatin |
WO2009087660A1 (fr) | 2007-11-12 | 2009-07-16 | Intas Pharmaceuticals Limited | Composition d'oxaliplatine stable pour une administration parentérale |
US20090221622A1 (en) * | 2008-02-29 | 2009-09-03 | Eagle Pharmaceuticals, Inc. | Topotecan ready to use solutions |
WO2010056847A2 (fr) * | 2008-11-13 | 2010-05-20 | Taigen Biotechnology Co., Ltd. | Formule lyophilisée |
WO2011034394A2 (fr) | 2009-09-21 | 2011-03-24 | 주식회사 중외제약 | Nanoparticules d'oxaliplatine et leur procédé de préparation |
US9387152B2 (en) | 2010-06-28 | 2016-07-12 | The General Hospital Corporation | Blood substitutes and uses thereof |
CN102274171A (zh) * | 2011-08-04 | 2011-12-14 | 上海希迪制药有限公司 | 一种奥沙利铂注射剂 |
MX363455B (es) | 2012-07-18 | 2019-03-25 | Onyx Therapeutics Inc | Composiciones liposómicas de inhibidores de proteasoma basadas en epoxicetona. |
JP5929607B2 (ja) * | 2012-08-06 | 2016-06-08 | ニプロ株式会社 | オキサリプラチン製剤 |
CN102885765B (zh) * | 2012-10-25 | 2013-11-06 | 哈药集团生物工程有限公司 | 一种盐酸伊立替康注射液及其制备方法 |
US10098813B2 (en) * | 2014-09-03 | 2018-10-16 | Sun Pharmaceutical Industries Limited | Perfusion dosage form |
KR101683635B1 (ko) * | 2014-12-29 | 2016-12-09 | 가천대학교 산학협력단 | 락테이트 금속염을 포함하는 암 치료용 약학 조성물 |
KR102293907B1 (ko) * | 2015-06-30 | 2021-08-26 | 한미약품 주식회사 | 이리노테칸 함유 경구용 고형제제 및 그 제조방법 |
CN109069342A (zh) | 2016-02-09 | 2018-12-21 | 太阳医药工业有限公司 | 灌注系统 |
US11339209B2 (en) | 2016-11-14 | 2022-05-24 | Novartis Ag | Compositions, methods, and therapeutic uses related to fusogenic protein minion |
MX2020007462A (es) | 2018-01-12 | 2020-09-14 | Metimedi Pharmaceuticals Co Ltd | Metodos de tratamiento de enfermedades inflamatorias cronicas. |
KR101998246B1 (ko) | 2018-08-22 | 2019-07-10 | 주식회사 메타파인즈 | 금속이온에 결합된 이온화합물을 포함하는 암 치료용 약학 조성물 |
Family Cites Families (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6041077B2 (ja) | 1976-09-06 | 1985-09-13 | 喜徳 喜谷 | 1,2‐ジアミノシクロヘキサン異性体のシス白金(2)錯体 |
US5041578A (en) * | 1988-11-22 | 1991-08-20 | Board Of Regents, The University Of Texas System | Water soluble 1,2-diaminocyclohexane platinum (IV) complexes as antitumor agents |
ATE247471T1 (de) | 1991-11-15 | 2003-09-15 | Smithkline Beecham Corp | Cisplatin und topotecan enthaltende zusammensetzung als antitumor. |
JPH0776230B2 (ja) | 1992-01-13 | 1995-08-16 | 田中貴金属工業株式会社 | 白金化合物の製造方法 |
JPH06287021A (ja) | 1992-04-22 | 1994-10-11 | Tanaka Kikinzoku Kogyo Kk | 光学活性な白金錯化合物の光学的分割方法 |
JP2673331B2 (ja) | 1993-01-12 | 1997-11-05 | 田中貴金属工業 株式会社 | 光学的に高純度なシス―オキザラート(トランス―1―1,2―シクロヘキサンジアミン)白金(▲ii▼) |
WO1994012193A1 (fr) | 1992-11-24 | 1994-06-09 | Debiopharm S.A. | Combinaison de cisplatine avec l'oxaliplatine |
CA2308082A1 (fr) * | 1992-11-27 | 1994-06-09 | Paul Handreck | Composition injectable |
JP3025602B2 (ja) | 1993-05-21 | 2000-03-27 | デビオファーム エス.アー. | 光学的に高純度なシス−オキザラート(トランス−l−1,2−シクロヘキサンジアミン)白金(II)錯体の製造方法 |
US5455270A (en) * | 1993-08-11 | 1995-10-03 | Bristol-Myers Squibb Co. | Stabilized solutions of platinum(II) antitumor agents |
UA42779C2 (uk) | 1994-08-08 | 2001-11-15 | Дебіофарм С.А. | Фармацевтично стійкий препарат оксалату платини для парентерального застосування |
EP0715854B1 (fr) | 1994-11-11 | 2003-09-10 | Debiopharm S.A. | Compositions carcinostatiques contenant du cis-oxaliplatine et un ou plusieurs autres carcinostatiques |
US5919816A (en) | 1994-11-14 | 1999-07-06 | Bionumerik Pharmaceuticals, Inc. | Formulations and methods of reducing toxicity of antineoplastic agents |
AU4842996A (en) * | 1995-02-28 | 1996-09-18 | Yoshinori Kidani | Novel platinum (iv) complexes, process for producing the same, and carcinostatic agents containing the same |
US5776959A (en) | 1995-06-05 | 1998-07-07 | Washington University | Anticonvulsant and anxiolytic lactam and thiolactam derivatives |
EP0897389B1 (fr) * | 1996-03-11 | 2002-07-03 | Yoshinori Kidani | Complexes de platine dinucleaires, procede pour leur preparation et compositions pharmaceutiques en contenant |
JP3154399B2 (ja) | 1996-07-04 | 2001-04-09 | デビオファーム エス.アー. | 白金化合物の製造方法 |
EP0929293B1 (fr) | 1996-08-23 | 2003-10-22 | Sequus Pharmaceuticals, Inc. | Liposomes contenant un compose cisplatine |
US6056973A (en) | 1996-10-11 | 2000-05-02 | Sequus Pharmaceuticals, Inc. | Therapeutic liposome composition and method of preparation |
NZ337502A (en) | 1997-02-05 | 2001-02-23 | Upjohn Co | Lipid complexes and liposomes of highly insoluble platinum complexes |
ATE338553T1 (de) | 1997-03-07 | 2006-09-15 | Sanofi Aventis Us Llc | Antitumorkombination aus 3-amino-1,2,4- benzotriazine 1,4-dioxid/paclitaxel/platin |
GB9727523D0 (en) | 1997-12-31 | 1998-02-25 | Pharmacia & Upjohn Spa | Alpha-aminoamide derivatives useful as analgesic agents |
GB9804013D0 (en) * | 1998-02-25 | 1998-04-22 | Sanofi Sa | Formulations |
PT1121117E (pt) | 1998-10-14 | 2002-10-31 | Debiopharm Sa | Acondicionamento de uma preparacao de oxaliplatina |
DE60005376T2 (de) | 1999-08-30 | 2004-07-01 | Debiopharm S.A. | Oxaliplatinhaltige parenteral anzuwendende stabilisierte arzneizubereitung und verfahren zu deren herstellung |
WO2001066102A2 (fr) | 2000-03-08 | 2001-09-13 | Bristol-Myers Squibb Company | Forme posologique orale d'administration de la combinaison de tegafur, uracile, acide folique et oxaliplatine et procede d'utilisation correspondant |
SE0003026D0 (sv) * | 2000-08-25 | 2000-08-25 | Kerstin Sunnerheim | Use for conifer sapling protection |
-
2001
- 2001-12-06 US US10/010,122 patent/US6476068B1/en not_active Expired - Fee Related
-
2002
- 2002-08-22 US US10/225,607 patent/US6673805B2/en not_active Expired - Fee Related
- 2002-11-15 US US10/295,799 patent/US20030109515A1/en not_active Abandoned
- 2002-11-22 BR BR0214757-2A patent/BR0214757A/pt not_active IP Right Cessation
- 2002-11-22 HU HU0402217A patent/HUP0402217A3/hu unknown
- 2002-11-22 KR KR1020047008709A patent/KR100941210B1/ko not_active IP Right Cessation
- 2002-11-22 RS YUP-597/04A patent/RS50360B/sr unknown
- 2002-11-22 WO PCT/EP2002/013146 patent/WO2003047587A1/fr active IP Right Grant
- 2002-11-22 DK DK02787779T patent/DK1453517T3/da active
- 2002-11-22 AT AT02787779T patent/ATE317260T1/de active
- 2002-11-22 NZ NZ533383A patent/NZ533383A/en not_active IP Right Cessation
- 2002-11-22 GE GE5607A patent/GEP20063895B/en unknown
- 2002-11-22 ES ES02787779T patent/ES2258661T3/es not_active Expired - Lifetime
- 2002-11-22 EP EP02787779A patent/EP1453517B1/fr not_active Expired - Lifetime
- 2002-11-22 MX MXPA04005423A patent/MXPA04005423A/es active IP Right Grant
- 2002-11-22 PL PL370254A patent/PL206755B1/pl not_active IP Right Cessation
- 2002-11-22 UA UA20040705324A patent/UA77728C2/uk unknown
- 2002-11-22 ME MEP-104/08A patent/MEP10408A/xx unknown
- 2002-11-22 CA CA002468916A patent/CA2468916C/fr not_active Expired - Fee Related
- 2002-11-22 AU AU2002352105A patent/AU2002352105B2/en not_active Ceased
- 2002-11-22 DE DE60209145T patent/DE60209145T2/de not_active Expired - Lifetime
- 2002-11-22 AP APAP/P/2004/003055A patent/AP1760A/en active
- 2002-11-22 IL IL16234802A patent/IL162348A0/xx unknown
- 2002-11-22 OA OA1200400165A patent/OA12739A/en unknown
- 2002-11-22 CN CNB028268431A patent/CN100540006C/zh not_active Expired - Fee Related
- 2002-11-22 JP JP2003548842A patent/JP2005515202A/ja not_active Withdrawn
- 2002-11-22 RO ROA200400514A patent/RO121509B1/ro unknown
- 2002-11-22 SI SI200220035A patent/SI21493A/sl not_active IP Right Cessation
- 2002-11-22 PT PT02787779T patent/PT1453517E/pt unknown
- 2002-11-22 EA EA200400777A patent/EA008090B1/ru not_active IP Right Cessation
- 2002-12-04 AR ARP020104679A patent/AR037629A1/es unknown
- 2002-12-04 MY MYPI20024553A patent/MY134422A/en unknown
- 2002-12-05 TW TW091135278A patent/TW200409640A/zh unknown
-
2004
- 2004-06-03 IL IL162348A patent/IL162348A/en not_active IP Right Cessation
- 2004-06-03 IS IS7298A patent/IS2580B/is unknown
- 2004-06-04 EC EC2004005140A patent/ECSP045140A/es unknown
- 2004-06-04 CR CR7362A patent/CR7362A/es not_active Application Discontinuation
- 2004-06-04 MA MA27715A patent/MA27153A1/fr unknown
- 2004-06-04 TN TNP2004000104A patent/TNSN04104A1/fr unknown
- 2004-06-07 HR HR20040514A patent/HRP20040514A2/hr not_active Application Discontinuation
- 2004-06-07 CO CO04053199A patent/CO5580776A2/es not_active Application Discontinuation
- 2004-06-08 ZA ZA200404525A patent/ZA200404525B/en unknown
- 2004-07-05 NO NO20042842A patent/NO330159B1/no not_active IP Right Cessation
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2005
- 2005-06-08 HK HK05104822.1A patent/HK1072002A1/xx not_active IP Right Cessation
-
2006
- 2006-05-04 CY CY20061100574T patent/CY1105608T1/el unknown
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