PT1957074E - Formulações de quinolinonas - Google Patents
Formulações de quinolinonas Download PDFInfo
- Publication number
- PT1957074E PT1957074E PT68385905T PT06838590T PT1957074E PT 1957074 E PT1957074 E PT 1957074E PT 68385905 T PT68385905 T PT 68385905T PT 06838590 T PT06838590 T PT 06838590T PT 1957074 E PT1957074 E PT 1957074E
- Authority
- PT
- Portugal
- Prior art keywords
- quinolinones
- formulations
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US74057705P | 2005-11-29 | 2005-11-29 | |
US74131705P | 2005-12-01 | 2005-12-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT1957074E true PT1957074E (pt) | 2014-06-25 |
Family
ID=38024178
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT68385905T PT1957074E (pt) | 2005-11-29 | 2006-11-29 | Formulações de quinolinonas |
Country Status (23)
Country | Link |
---|---|
US (2) | US20080293738A1 (pt) |
EP (2) | EP2772257A1 (pt) |
JP (1) | JP2009517481A (pt) |
KR (1) | KR20080074143A (pt) |
CN (1) | CN102670530A (pt) |
AR (1) | AR062545A1 (pt) |
AU (1) | AU2006320591B2 (pt) |
BR (1) | BRPI0619370A2 (pt) |
CA (1) | CA2627544C (pt) |
CL (1) | CL2010000387A1 (pt) |
EC (1) | ECSP088467A (pt) |
ES (1) | ES2467162T3 (pt) |
IL (1) | IL190865A0 (pt) |
MA (1) | MA29969B1 (pt) |
MY (1) | MY148529A (pt) |
NO (1) | NO20082938L (pt) |
NZ (1) | NZ567550A (pt) |
PE (1) | PE20070760A1 (pt) |
PL (1) | PL1957074T3 (pt) |
PT (1) | PT1957074E (pt) |
RU (1) | RU2433826C2 (pt) |
TW (1) | TW200730176A (pt) |
WO (1) | WO2007064719A2 (pt) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR070924A1 (es) * | 2008-03-19 | 2010-05-12 | Novartis Ag | Formas cristalinas y dos formas solvatadas de sales del acido lactico de 4- amino -5- fluoro-3-(5-(4-metilpiperazin-1-il ) -1h- bencimidazol-2-il) quinolin -2-(1h) - ona |
MX2010012814A (es) | 2008-05-23 | 2010-12-20 | Amira Pharmaceuticals Inc | Inhibidor de proteina activadora de 5-lipoxigenasa. |
MX2010014566A (es) * | 2008-07-03 | 2011-02-15 | Novartis Ag | Proceso de granulacion de fundido. |
UY33472A (es) * | 2010-06-30 | 2012-01-31 | Novartis Ag | ?composiciones farmacéuticas que comprenden monohidrato de lactato de 4-amino-5-fluoro-3-[6-(4-metil-piperazin-1-il)-1hbencimidazol-2-il]-1h-quinolin-2-ona?. |
WO2013063003A1 (en) | 2011-10-28 | 2013-05-02 | Novartis Ag | Method of treating gastrointestinal stromal tumors |
BR112014017985A8 (pt) | 2012-01-31 | 2017-07-11 | Novartis Ag | Combinação de um inibidor de rtk com um antiestrogênio e uso da mesma para o tratamento de cancer |
BR112015000349A2 (pt) | 2012-07-11 | 2017-06-27 | Novartis Ag | método de tratamento de tumores estromais gastrointestinais |
WO2014058785A1 (en) | 2012-10-10 | 2014-04-17 | Novartis Ag | Combination therapy |
TWI535784B (zh) | 2014-08-26 | 2016-06-01 | 財團法人工業技術研究院 | 剪切增稠配方、及包含其之複合材料 |
JP7469308B2 (ja) | 2018-12-06 | 2024-04-16 | グラクソスミスクライン、インテレクチュアル、プロパティー、ディベロップメント、リミテッド | 新規の医薬製剤 |
Family Cites Families (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3663606A (en) * | 1966-06-21 | 1972-05-16 | Mitsui Toatsu Chemicals | Organic imino-compounds |
DE2363459A1 (de) | 1973-12-20 | 1975-06-26 | Basf Ag | Neue fluoreszierende chinolinverbindungen |
US4119105A (en) | 1977-01-31 | 1978-10-10 | Olin Corporation | Air flow limiting filter |
JPH0699497B2 (ja) | 1987-04-16 | 1994-12-07 | 富士写真フイルム株式会社 | 光重合性組成物 |
GB9108547D0 (en) | 1991-04-22 | 1991-06-05 | Fujisawa Pharmaceutical Co | Quinoline derivatives |
US5480883A (en) * | 1991-05-10 | 1996-01-02 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Bis mono- and bicyclic aryl and heteroaryl compounds which inhibit EGF and/or PDGF receptor tyrosine kinase |
JP3161780B2 (ja) | 1991-09-30 | 2001-04-25 | 東レ・ダウコーニング・シリコーン株式会社 | α,ω−ジヒドロキシフルオロアルキルメチルポリシロキサンの製造方法 |
JP3142378B2 (ja) | 1992-06-22 | 2001-03-07 | ティーディーケイ株式会社 | 有機el素子 |
US5763441A (en) | 1992-11-13 | 1998-06-09 | Sugen, Inc. | Compounds for the treatment of disorders related to vasculogenesis and/or angiogenesis |
JPH0743896A (ja) | 1993-07-28 | 1995-02-14 | Toyobo Co Ltd | 光重合性組成物 |
JPH0829973A (ja) | 1994-07-11 | 1996-02-02 | Toyobo Co Ltd | 光重合性組成物 |
JP3441246B2 (ja) | 1995-06-07 | 2003-08-25 | 富士写真フイルム株式会社 | 光重合性組成物 |
GB9624482D0 (en) | 1995-12-18 | 1997-01-15 | Zeneca Phaema S A | Chemical compounds |
US6010711A (en) * | 1996-01-26 | 2000-01-04 | University Of Rochester | Methods, articles and compositions for the pharmacologic inhibition of bone resorption with phosphodiesterase inhibitors |
DE69734149T2 (de) | 1996-03-15 | 2006-07-06 | Astrazeneca Ab | Cinoline derivate und verwendung als heilmittel |
DE19610723A1 (de) | 1996-03-19 | 1997-09-25 | Bayer Ag | Elektrolumineszierende Anordnungen unter Verwendung von Blendsystemen |
CN1226245A (zh) | 1996-06-20 | 1999-08-18 | 德克萨斯州大学系统董事会 | 具有药理活性的化合物,其制备方法及其用途 |
AU733551B2 (en) | 1996-09-25 | 2001-05-17 | Astrazeneca Ab | Qinoline derivatives inhibiting the effect of growth factors such as VEGF |
US20030027818A1 (en) * | 2001-04-03 | 2003-02-06 | Redmond H. Paul | Treatment of cancers |
GB9716557D0 (en) * | 1997-08-06 | 1997-10-08 | Glaxo Group Ltd | Benzylidene-1,3-dihydro-indol-2-one derivatives having anti-cancer activity |
US6294532B1 (en) | 1997-08-22 | 2001-09-25 | Zeneca Limited | Oxindolylquinazoline derivatives as angiogenesis inhibitors |
AU3850299A (en) | 1998-05-20 | 1999-12-06 | Kyowa Hakko Kogyo Co. Ltd. | Vegf activity inhibitors |
US6138605A (en) | 1998-08-05 | 2000-10-31 | Seascape Systems Limited | Access and evacuation apparatus with articulated arm |
DE19841985A1 (de) | 1998-09-03 | 2000-03-09 | Schering Ag | Dialkylsulfonsäure- und Dialkylcarbonsäure-Derivate |
IL126953A0 (en) | 1998-11-08 | 1999-09-22 | Yeda Res & Dev | Pharmaceutical compositions comprising porphyrins and some novel porphyrin derivatives |
PE20010306A1 (es) | 1999-07-02 | 2001-03-29 | Agouron Pharma | Compuestos de indazol y composiciones farmaceuticas que los contienen utiles para la inhibicion de proteina kinasa |
US7045133B2 (en) | 2000-01-18 | 2006-05-16 | Ludwig Institute For Cancer Research | VEGF-D/VEGF-C/VEGF peptidomimetic inhibitor |
YU54202A (sh) | 2000-01-18 | 2006-01-16 | Agouron Pharmaceuticals Inc. | Jedinjenja indazola, farmaceutske smeše i postupci za stimulisanje i inhibiranje ćelijske proliferacije |
CN101053573A (zh) | 2000-01-19 | 2007-10-17 | 帕卡什·S·吉尔 | 针对反义vegf寡核苷酸的方法和组合物 |
GB0001930D0 (en) | 2000-01-27 | 2000-03-22 | Novartis Ag | Organic compounds |
CA2402589C (en) * | 2000-03-07 | 2011-02-01 | Sanjay Garg | Compositions and methods for trapping and inactivating pathogenic microbes and spermatozoa |
EP1313734B1 (en) | 2000-09-01 | 2009-11-11 | Novartis Vaccines and Diagnostics, Inc. | Aza heterocyclic derivatives and their therapeutic use |
AP1666A (en) | 2000-09-11 | 2006-09-29 | Chiron Corp | Quinolinone derivatives as tyrosine kinase inhibitors. |
US20030028018A1 (en) | 2000-09-11 | 2003-02-06 | Chiron Coporation | Quinolinone derivatives |
US6476068B1 (en) * | 2001-12-06 | 2002-11-05 | Pharmacia Italia, S.P.A. | Platinum derivative pharmaceutical formulations |
WO2004018419A2 (en) | 2002-08-23 | 2004-03-04 | Chiron Corporation | Benzimidazole quinolinones and uses thereof |
US7825132B2 (en) * | 2002-08-23 | 2010-11-02 | Novartis Vaccines And Diagnostics, Inc. | Inhibition of FGFR3 and treatment of multiple myeloma |
BR0316229A (pt) | 2002-11-13 | 2005-10-04 | Chiron Corp | Métodos de tratamento de câncer e métodos relacionados |
EP1682529A4 (en) | 2003-11-07 | 2010-06-30 | Novartis Vaccines & Diagnostic | METHODS FOR SYNTHESIS OF QUINOLINONE COMPOUNDS |
EP1718306A2 (en) * | 2004-02-20 | 2006-11-08 | Chiron Corporation | Modulation of inflammatory and metastatic processes |
MX2007014612A (es) * | 2005-05-18 | 2008-01-17 | M & G Polimeri Italia Spa | Composicion de poliester. |
EP2270000B1 (en) * | 2005-05-23 | 2015-07-29 | Novartis AG | Crystalline and other forms of 4-amino-5-fluoro-3-[6-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-1H-quinolin-2-one lactic acid salts |
-
2006
- 2006-11-29 AR ARP060105279A patent/AR062545A1/es unknown
- 2006-11-29 EP EP14150490.2A patent/EP2772257A1/en not_active Withdrawn
- 2006-11-29 KR KR1020087012826A patent/KR20080074143A/ko not_active Application Discontinuation
- 2006-11-29 AU AU2006320591A patent/AU2006320591B2/en not_active Ceased
- 2006-11-29 JP JP2008543426A patent/JP2009517481A/ja active Pending
- 2006-11-29 US US12/094,806 patent/US20080293738A1/en not_active Abandoned
- 2006-11-29 CA CA2627544A patent/CA2627544C/en not_active Expired - Fee Related
- 2006-11-29 PL PL06838590T patent/PL1957074T3/pl unknown
- 2006-11-29 EP EP06838590.5A patent/EP1957074B1/en active Active
- 2006-11-29 WO PCT/US2006/045711 patent/WO2007064719A2/en active Application Filing
- 2006-11-29 RU RU2008126384/15A patent/RU2433826C2/ru not_active IP Right Cessation
- 2006-11-29 CN CN2012100464971A patent/CN102670530A/zh active Pending
- 2006-11-29 TW TW095144180A patent/TW200730176A/zh unknown
- 2006-11-29 PE PE2006001517A patent/PE20070760A1/es not_active Application Discontinuation
- 2006-11-29 NZ NZ567550A patent/NZ567550A/en not_active IP Right Cessation
- 2006-11-29 PT PT68385905T patent/PT1957074E/pt unknown
- 2006-11-29 BR BRPI0619370-6A patent/BRPI0619370A2/pt not_active IP Right Cessation
- 2006-11-29 ES ES06838590.5T patent/ES2467162T3/es active Active
- 2006-11-29 MY MYPI20081687A patent/MY148529A/en unknown
-
2008
- 2008-04-14 IL IL190865A patent/IL190865A0/en unknown
- 2008-05-20 MA MA30953A patent/MA29969B1/fr unknown
- 2008-05-23 EC EC2008008467A patent/ECSP088467A/es unknown
- 2008-06-30 NO NO20082938A patent/NO20082938L/no not_active Application Discontinuation
-
2010
- 2010-04-19 CL CL2010000387A patent/CL2010000387A1/es unknown
-
2012
- 2012-07-05 US US13/542,216 patent/US20120276200A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
PE20070760A1 (es) | 2007-10-04 |
MA29969B1 (fr) | 2008-11-03 |
WO2007064719A3 (en) | 2007-08-16 |
CN102670530A (zh) | 2012-09-19 |
ECSP088467A (es) | 2008-06-30 |
MY148529A (en) | 2013-04-30 |
EP1957074B1 (en) | 2014-03-19 |
NO20082938L (no) | 2008-06-30 |
US20120276200A1 (en) | 2012-11-01 |
TW200730176A (en) | 2007-08-16 |
RU2433826C2 (ru) | 2011-11-20 |
CA2627544C (en) | 2015-07-07 |
JP2009517481A (ja) | 2009-04-30 |
AU2006320591A1 (en) | 2007-06-07 |
AR062545A1 (es) | 2008-11-19 |
ES2467162T3 (es) | 2014-06-12 |
NZ567550A (en) | 2011-08-26 |
RU2008126384A (ru) | 2010-01-10 |
PL1957074T3 (pl) | 2014-08-29 |
BRPI0619370A2 (pt) | 2011-09-27 |
CL2010000387A1 (es) | 2010-08-06 |
CA2627544A1 (en) | 2007-06-07 |
IL190865A0 (en) | 2008-11-03 |
KR20080074143A (ko) | 2008-08-12 |
US20080293738A1 (en) | 2008-11-27 |
EP1957074A2 (en) | 2008-08-20 |
EP2772257A1 (en) | 2014-09-03 |
AU2006320591B2 (en) | 2010-06-03 |
WO2007064719A2 (en) | 2007-06-07 |
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