EP0194599A3
(fr)
|
1985-03-14 |
1988-01-20 |
Nissan Chemical Industries Ltd. |
Dérivés de benzamide, leur procédé de préparation et fongicides pour le sol les contenant
|
GB9122590D0
(en)
|
1991-10-24 |
1991-12-04 |
Lilly Industries Ltd |
Pharmaceutical compounds
|
DE4410453A1
(de)
|
1994-03-25 |
1995-09-28 |
Hoechst Ag |
Substituierte heterocyclische Carbonsäureamidester, ihre Herstellung und ihre Verwendung als Arzneimittel
|
GB9514160D0
(en)
|
1994-07-25 |
1995-09-13 |
Zeneca Ltd |
Aromatic compounds
|
CA2209902A1
(fr)
|
1995-01-19 |
1996-07-25 |
Novartis Ag |
Composition herbicide
|
EA001418B1
(ru)
|
1995-11-23 |
2001-02-26 |
Новартис Аг |
Гербицидная композиция
|
CA2238875C
(fr)
|
1995-12-15 |
2003-09-16 |
Merck Frosst Canada Inc. |
Derives d'ethane tri-aryle utilises comme inhibiteurs de pde iv
|
JPH10114654A
(ja)
|
1996-10-09 |
1998-05-06 |
Fujisawa Pharmaceut Co Ltd |
新規用途
|
WO1998031226A1
(fr)
|
1997-01-15 |
1998-07-23 |
Novartis Ag |
Agent herbicide
|
GB9716657D0
(en)
|
1997-08-07 |
1997-10-15 |
Zeneca Ltd |
Chemical compounds
|
DE19742951A1
(de)
|
1997-09-29 |
1999-04-15 |
Hoechst Schering Agrevo Gmbh |
Acylsulfamoylbenzoesäureamide, diese enthaltende nutzpflanzenschützende Mittel und Verfahren zu ihrer Herstellung
|
US20020017295A1
(en)
|
2000-07-07 |
2002-02-14 |
Weers Jeffry G. |
Phospholipid-based powders for inhalation
|
DE19802697A1
(de)
|
1998-01-24 |
1999-07-29 |
Bayer Ag |
Selektive Herbizide auf Basis von N-Aryl-triazolin(thi)onen und N-Arylsulfonylamino(thio)carbonyltriazolin(thi)onen
|
US6610853B1
(en)
|
1998-02-13 |
2003-08-26 |
Kureha Kagaku Kogyo K.K. |
N-(phenylsulfonyl)picolinamide derivatives, process for producing the same, and herbicide
|
EP1070705A4
(fr)
|
1998-04-06 |
2002-04-17 |
Fujisawa Pharmaceutical Co |
Derives d'indole
|
HUP0201586A2
(en)
|
1999-06-10 |
2002-08-28 |
Warner Lambert Co |
Method of inhibiting amyloid protein aggregation and imaging amyloid deposits using isoindoline derivatives
|
DE19936438A1
(de)
|
1999-08-03 |
2001-02-08 |
Aventis Cropscience Gmbh |
Kombinationen von Herbiziden und Safenern
|
DE19940860A1
(de)
|
1999-08-27 |
2001-03-01 |
Bayer Ag |
Selektive Herbizide auf Basis eines substituierten Phenylsulfonyl aminocarbonyltriazolinons und Safenern II
|
DE19958381A1
(de)
|
1999-12-03 |
2001-06-07 |
Bayer Ag |
Herbizide auf Basis von N-Aryl-uracilen
|
US6777400B2
(en)
|
2000-08-05 |
2004-08-17 |
Smithkline Beecham Corporation |
Anti-inflammatory androstane derivative compositions
|
WO2002015902A1
(fr)
|
2000-08-23 |
2002-02-28 |
Merck & Co., Inc. |
Procede pour traiter et prevenir l'incontinence urinaire par utilisation d'antagonistes de recepteur ep1 de prostanoide
|
UY26942A1
(es)
|
2000-09-20 |
2002-04-26 |
Abbott Lab |
N-acilsulfonamidas promotoras de la apoptosis
|
US20020055631A1
(en)
|
2000-09-20 |
2002-05-09 |
Augeri David J. |
N-acylsulfonamide apoptosis promoters
|
US6720338B2
(en)
|
2000-09-20 |
2004-04-13 |
Abbott Laboratories |
N-acylsulfonamide apoptosis promoters
|
CA2427499A1
(fr)
|
2000-10-10 |
2002-04-18 |
Smithkline Beecham Corporation |
Indoles substituees, compositions pharmaceutiques contenant ces indoles et leur utilisation comme agent de fixation de ppar-.gamma.
|
US20100074949A1
(en)
|
2008-08-13 |
2010-03-25 |
William Rowe |
Pharmaceutical composition and administration thereof
|
DE10119721A1
(de)
|
2001-04-21 |
2002-10-31 |
Bayer Cropscience Gmbh |
Herbizide Mittel enthaltend Benzoylcyclohexandione und Safener
|
ATE372987T1
(de)
|
2001-05-31 |
2007-09-15 |
Vicore Pharma Ab |
Trizyklische verbindungen, nützlich als angiotensin ii agonisten
|
DE60228447D1
(de)
|
2001-06-28 |
2008-10-02 |
Pfizer Prod Inc |
Triamidsubstituierte indole, benzofurane und benzothiophene als inhibitoren des mikrosomalen triglyceridtransferproteins (mtp) und/oder der sekretion von apolipoprotein b (apo b)
|
DE10145019A1
(de)
|
2001-09-13 |
2003-04-03 |
Bayer Cropscience Gmbh |
Kombinationen aus Herbiziden und Safenern
|
DE10146873A1
(de)
|
2001-09-24 |
2003-04-17 |
Bayer Cropscience Gmbh |
Heterocyclische Amide und -Iminderivate, Verfahren zu ihrer Herstellung, sie enthaltende Mittel und ihre Verwendung als Schädlingsbekämpfungsmittel
|
HUP0501067A2
(en)
|
2001-11-14 |
2006-02-28 |
Teva Pharma |
Amorphous and crystalline forms of losartan potassium and process for their preparation
|
JPWO2003043655A1
(ja)
|
2001-11-19 |
2005-03-10 |
小野薬品工業株式会社 |
頻尿の治療剤
|
DE10157545A1
(de)
|
2001-11-23 |
2003-06-12 |
Bayer Cropscience Gmbh |
Herbizide Mittel enthaltend Benzoylpyrazole und Safener
|
US7247748B2
(en)
|
2002-03-27 |
2007-07-24 |
Smithkline Corporation |
Amide compounds and methods of using the same
|
GB0212785D0
(en)
|
2002-05-31 |
2002-07-10 |
Glaxo Group Ltd |
Compounds
|
EP1515606B1
(fr)
|
2002-06-08 |
2006-04-26 |
Bayer CropScience GmbH |
Combinaisons d'acides carboxyliques aromatiques herbicides et de phytoprotecteurs
|
DE10237461A1
(de)
|
2002-08-16 |
2004-02-26 |
Bayer Cropscience Gmbh |
Herbizide Mittel enthaltend Benzoylpyrazole und Safener
|
US20060019932A1
(en)
|
2002-09-06 |
2006-01-26 |
Mancini Joseph A |
Treatment of rheumatoid arthritis by inhibition of pde4
|
CA2503063A1
(fr)
|
2002-10-22 |
2004-05-06 |
Merck Frosst Canada & Co./Merck Frosst Canada & Cie |
Inhibiteurs selectifs de la cyclo-oxygenase-2 liberant de l'oxyde nitrique
|
GB0225548D0
(en)
|
2002-11-01 |
2002-12-11 |
Glaxo Group Ltd |
Compounds
|
AU2003302106A1
(en)
|
2002-11-21 |
2004-06-15 |
Vicore Pharma Ab |
New tricyclic angiotensin ii agonists
|
JP2006514032A
(ja)
|
2002-12-20 |
2006-04-27 |
ファイザー・プロダクツ・インク |
ミクロソームトリグリセリド転送タンパク質阻害剤
|
BR0317426A
(pt)
|
2002-12-20 |
2005-11-16 |
Pfizer Prod Inc |
Inibidores de proteìna de transferência de triglicéridos microssomais
|
AU2004218456A1
(en)
|
2003-02-28 |
2004-09-16 |
Encysive Pharmaceuticals Inc. |
Pyridine, pyrimidine, quinoline, quinazoline, and naphthalene urotensin-II receptor antagonists.
|
AU2003219291A1
(en)
|
2003-03-24 |
2004-10-18 |
Vicore Pharma Ab |
Bicyclic compounds useful as angiotensin ii agonists
|
ATE440825T1
(de)
|
2003-06-06 |
2009-09-15 |
Vertex Pharma |
Pyrimidin-derivate zur verwendung als modulatoren von atp-bindende kassette transportern
|
EP1682127B1
(fr)
|
2003-11-14 |
2009-07-29 |
Vertex Pharmaceuticals Incorporated |
Thiazoles et oxazoles utiles en tant que modulateurs de transporteurs de type cassette de liaison a l'atp
|
GB0328024D0
(en)
|
2003-12-03 |
2004-01-07 |
Glaxo Group Ltd |
Compounds
|
CA2554716A1
(fr)
|
2004-01-22 |
2005-08-04 |
Nitromed, Inc. |
Composes nitroses et/ou nitrosyles, compositions et procede pour les utiliser
|
WO2005075435A1
(fr)
|
2004-01-30 |
2005-08-18 |
Vertex Pharmaceuticals Incorporated |
Modulateurs de transporteurs de type cassette de liaison a l'atp
|
US7977322B2
(en)
|
2004-08-20 |
2011-07-12 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-binding cassette transporters
|
AU2005214159A1
(en)
|
2004-02-04 |
2005-09-01 |
Pfizer Products Inc. |
Substituted quinoline compounds
|
US20050197376A1
(en)
|
2004-03-02 |
2005-09-08 |
Fujisawa Pharmaceutical Co. Ltd. |
Concomitant drugs
|
CA2558848C
(fr)
|
2004-03-05 |
2013-11-19 |
Nissan Chemical Industries, Ltd. |
Compose de benzamide a substitution isoxazoline et pesticide
|
WO2005099705A2
(fr)
|
2004-03-24 |
2005-10-27 |
Bayer Pharmaceuticals Corporation |
Preparation de derives imidazoles et leurs procedes d'utilisation
|
GB0410121D0
(en)
|
2004-05-06 |
2004-06-09 |
Glaxo Group Ltd |
Compounds
|
US8354427B2
(en)
|
2004-06-24 |
2013-01-15 |
Vertex Pharmaceutical Incorporated |
Modulators of ATP-binding cassette transporters
|
NZ587547A
(en)
|
2004-06-24 |
2012-09-28 |
Vertex Pharma |
Modulators of ATP-Binding Cassette Transporters
|
CN101014572B
(zh)
|
2004-09-15 |
2011-07-06 |
盐野义制药株式会社 |
具有hiv整合酶抑制活性的氨基甲酰基吡啶酮衍生物
|
WO2006039212A2
(fr)
|
2004-09-29 |
2006-04-13 |
Portola Pharmaceuticals, Inc. |
2h-1,3-benzoxazin-4(3h)-ones substitues
|
US20080287399A1
(en)
|
2004-12-14 |
2008-11-20 |
Astrazeneca Ab |
Substituted Aminopyridines and Uses Thereof
|
DE602005013116D1
(de)
|
2004-12-23 |
2009-04-16 |
Glaxo Group Ltd |
Pyridin-verbindungen für die behandlung von prostaglandin-vermittelten krankheiten
|
GB0428173D0
(en)
|
2004-12-23 |
2005-01-26 |
Astrazeneca Ab |
Compounds
|
US8822451B2
(en)
|
2005-05-24 |
2014-09-02 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-binding cassette transporters
|
US20070032488A1
(en)
|
2005-08-05 |
2007-02-08 |
Genelabs Technologies, Inc. |
6-Membered aryl and heteroaryl derivatives for treating viruses
|
NZ566208A
(en)
|
2005-08-11 |
2010-09-30 |
Vertex Pharma |
2-Thiazolamide derivatives as modulators of cystic fibrosis transmembrane conductance regulators
|
WO2007053641A2
(fr)
|
2005-11-01 |
2007-05-10 |
Mars, Incorporated |
Procyanidines de type a et inflammation
|
EP1974212A1
(fr)
|
2005-12-27 |
2008-10-01 |
Vertex Pharmaceuticals Incorporated |
Composes utiles dans les bio-essais cftr et leurs procedes
|
ES2398319T3
(es)
|
2005-12-28 |
2013-03-15 |
Vertex Pharmaceuticals Incorporated |
Derivados de 1-(benzo[D][1,3]dioxol-5-il)-N-(fenil)ciclopropano-carboxamida y compuestos relacionados como moduladores de transportadores de casetes de unión a ATP para el tratamiento de la fibrosis quística
|
US7671221B2
(en)
|
2005-12-28 |
2010-03-02 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-Binding Cassette transporters
|
PL3219705T3
(pl)
|
2005-12-28 |
2020-08-10 |
Vertex Pharmaceuticals Incorporated |
Kompozycje farmaceutyczne amorficznych postaci n-[2,4-bis(1,1-dimetyloetylo)-5-hydroksyfenylo]-1,4-dihydro-4-oksochinolino-3-karboksyamidu
|
JP2009532437A
(ja)
|
2006-04-05 |
2009-09-10 |
バイエル・クロツプサイエンス・エス・アー |
殺菌剤n−シクロプロピル−スルホニルアミド誘導体
|
SI3091011T1
(en)
|
2006-04-07 |
2018-06-29 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP conveyor belt conveyors
|
ATE534383T1
(de)
|
2006-05-12 |
2011-12-15 |
Vertex Pharma |
Zusammensetzungen aus n-ä2,4-bis(1,1- dimethylethyl)-5-hydroxyphenylü-1,4-dihydro-4- oxochinolin-3-carboxamid
|
US8778977B2
(en)
|
2006-06-30 |
2014-07-15 |
Sunesis Pharmaceuticals, Inc. |
Pyridinonyl PDK1 inhibitors
|
NZ576642A
(en)
|
2006-11-03 |
2011-11-25 |
Vertex Pharma |
Azaindole derivatives as cftr modulators
|
US20090047246A1
(en)
|
2007-02-12 |
2009-02-19 |
Intermune, Inc. |
Novel inhibitors of hepatitis c virus replication
|
WO2008141385A1
(fr)
|
2007-05-21 |
2008-11-27 |
Biota Scientific Management Pty Ltd |
Inhibiteurs de polymérases virales
|
US8058299B2
(en)
|
2007-05-22 |
2011-11-15 |
Via Pharmaceuticals, Inc. |
Diacylglycerol acyltransferase inhibitors
|
US8173810B2
(en)
|
2007-05-25 |
2012-05-08 |
Amgen Inc. |
Substituted hydroxyethyl amine compounds as beta-secretase modulators and methods of use
|
GB0716532D0
(en)
|
2007-08-24 |
2007-10-03 |
Angeletti P Ist Richerche Bio |
Therapeutic compounds
|
BRPI0816116A2
(pt)
|
2007-08-29 |
2015-03-03 |
Schering Corp |
Derivados de indol 2,3-substituídos para o tratamento de infecções virais.
|
CN101918366A
(zh)
|
2007-09-14 |
2010-12-15 |
弗特克斯药品有限公司 |
N-[2,4-双(1,1-二甲基乙基)-5-羟基苯基]-1,4-二氢-4-氧代喹啉-3-甲酰胺的固体形式
|
AU2013231151B2
(en)
|
2007-11-16 |
2015-06-25 |
Vertex Pharmaceuticals Incorporated |
Isoquinoline modulators of ATP-Binding Cassette transporters
|
EP2222660B1
(fr)
|
2007-11-16 |
2014-03-26 |
Merck Sharp & Dohme Corp. |
Dérivés d'indole à substitution hétérocyclique en position 3 et leurs procédés d'utilisation
|
GB0723794D0
(en)
|
2007-12-05 |
2008-01-16 |
Lectus Therapeutics Ltd |
Potassium ion channel modulators and uses thereof
|
KR20150063170A
(ko)
|
2007-12-07 |
2015-06-08 |
버텍스 파마슈티칼스 인코포레이티드 |
3-(6-(1-(2,2-디플루오로벤조[d][1,3]디옥솔-5-일)사이클로프로판카복스아미도)-3-메틸피리딘-2-일)벤조산의 고체 형태
|
DK2639222T3
(en)
|
2007-12-07 |
2016-10-03 |
Vertex Pharma |
Methods for preparing cycloalkylcarboxamido-pyridinbenzoesyrer
|
AU2013270464B2
(en)
|
2008-03-31 |
2016-05-26 |
Vertex Pharmaceuticals Incorporated |
Pyridyl derivatives as CFTR modulators
|
US20110071197A1
(en)
|
2008-04-16 |
2011-03-24 |
Peter Nilsson |
Bis-aryl compounds for use as medicaments
|
US20110112193A1
(en)
|
2008-05-14 |
2011-05-12 |
Peter Nilsson |
Bis-aryl compounds for use as medicaments
|
EP2145537A1
(fr)
|
2008-07-09 |
2010-01-20 |
Bayer CropScience AG |
Régulateur de croissance végétale
|
UY31982A
(es)
|
2008-07-16 |
2010-02-26 |
Boehringer Ingelheim Int |
Derivados de 1,2-dihidropiridin-3-carboxamidas n-sustituidas
|
EP3842037A1
(fr)
|
2008-08-13 |
2021-06-30 |
Vertex Pharmaceuticals Incorporated |
Composition pharmaceutique et ses administrations
|
EP2326178A4
(fr)
|
2008-08-21 |
2012-10-24 |
Glaxosmithkline Llc |
Inhibiteurs de la prolyl-hydroxylase
|
EP2321303B1
(fr)
|
2008-08-27 |
2019-11-27 |
Calcimedica, Inc. |
Composés qui modulent le calcium intracellulaire
|
UA104876C2
(uk)
|
2008-11-06 |
2014-03-25 |
Вертекс Фармасьютікалз Інкорпорейтед |
Модулятори atф-зв'язувальних касетних транспортерів
|
ES2532753T3
(es)
|
2008-11-06 |
2015-03-31 |
Vertex Pharmaceuticals Incorporated |
Moduladores de transportadores del casete de unión a ATP
|
US20100160322A1
(en)
|
2008-12-04 |
2010-06-24 |
Abbott Laboratories |
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
|
UA108193C2
(uk)
|
2008-12-04 |
2015-04-10 |
|
Апоптозіндукуючий засіб для лікування раку і імунних і аутоімунних захворювань
|
SG193849A1
(en)
|
2009-01-19 |
2013-10-30 |
Abbott Lab |
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
|
JP5840955B2
(ja)
|
2009-03-11 |
2016-01-06 |
バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH |
ハロゲンアルキルメチレンオキシフェニル置換ケトエノール類
|
NZ624460A
(en)
|
2009-03-20 |
2015-12-24 |
Vertex Pharma |
Process for making modulators of cystic fibrosis transmembrane conductance regulator
|
JP5697163B2
(ja)
|
2009-03-26 |
2015-04-08 |
塩野義製薬株式会社 |
置換された3−ヒドロキシ−4−ピリドン誘導体
|
CN102458122A
(zh)
|
2009-04-20 |
2012-05-16 |
人类健康研究所 |
含有哒嗪磺胺衍生物的化合物、组合物和方法
|
SG10201704742YA
(en)
|
2009-05-26 |
2017-07-28 |
Abbvie Ireland Unlimited Co |
Apoptosis-inducing agents for the treatment of cancer and immune and autoimmune diseases
|
WO2011102514A1
(fr)
|
2010-02-22 |
2011-08-25 |
武田薬品工業株式会社 |
Composé cyclique aromatique
|
CN103180298A
(zh)
|
2010-03-19 |
2013-06-26 |
沃泰克斯药物股份有限公司 |
N-[2,4-双(1,1-二甲基乙基)-5-羟基苯基]-1,4-二氢-4-氧代喹啉-3-甲酰胺的固体形式
|
AU2011230508B2
(en)
|
2010-03-25 |
2016-04-28 |
Vertex Pharmaceuticals Incorporated |
Solid forms of (R)-1(2,2-difluorobenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihyderoxypropyl)-6-fluoro-2- (1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl) cyclopropanecarboxamide
|
HUE056525T2
(hu)
|
2010-04-07 |
2022-02-28 |
Vertex Pharma |
3-(6-(1-(2,2-Difluorbenzo[d][1,3]dioxol-5-il)ciklopropánkarboxamido)-3-metilpiridin-2-il)benzoesav gyógyszerészeti készítményei és azok adagolása
|
RU2579370C2
(ru)
|
2010-04-07 |
2016-04-10 |
Вертекс Фармасьютикалз Инкорпорейтед |
Твердые формы 3-(2, 2-дифторбензо[d][1, 3] диоксол-5-ил)циклопропанкарбоксамидо)-3-метилпиридин-2-ил)бензойной кислоты
|
US8344137B2
(en)
|
2010-04-14 |
2013-01-01 |
Hoffman-La Roche Inc. |
3,3-dimethyl tetrahydroquinoline derivatives
|
MX353408B
(es)
|
2010-04-22 |
2018-01-11 |
Vertex Pharma |
Proceso para producir compuestos de cicloalquilcarboxamido-indol.
|
NZ603042A
(en)
|
2010-04-22 |
2015-02-27 |
Vertex Pharma |
Pharmaceutical compositions comprising cftr modulators and administrations thereof
|
TWI520960B
(zh)
|
2010-05-26 |
2016-02-11 |
艾伯維有限公司 |
用於治療癌症及免疫及自體免疫疾病之細胞凋亡誘導劑
|
US8563593B2
(en)
|
2010-06-08 |
2013-10-22 |
Vertex Pharmaceuticals Incorporated |
Formulations of (R)-1-(2,2-difluorobenzo[D] [1,3] dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide
|
BR112013004443A8
(pt)
|
2010-08-23 |
2018-01-02 |
Vertex Pharma |
composições farmacêuticas de (r)-1-(2,2-difluorbenzo[d] [1,3]dioxol-5-il)-n-(1-(2,3-di-hidróxipropil)-6-flúor-2-(1-hidróxi-2-metilpropan-2-il)-1h-indol-5-il)ciclopropano carboxamida e administração das mesmas
|
EP2608775A2
(fr)
|
2010-08-27 |
2013-07-03 |
Vertex Pharmaceuticals Incorporated |
Composition pharmaceutique et ses administrations
|
US9394290B2
(en)
|
2010-10-21 |
2016-07-19 |
Universitaet Des Saarlandes Campus Saarbruecken |
Selective CYP11B1 inhibitors for the treatment of cortisol dependent diseases
|
WO2012087938A1
(fr)
|
2010-12-20 |
2012-06-28 |
Glaxosmithkline Llc |
Dérivés de quinazolinone en tant qu'agents antiviraux
|
EP2471363A1
(fr)
|
2010-12-30 |
2012-07-04 |
Bayer CropScience AG |
Utilisation d'acides aryl-, hétéroaryl- et benzylsulfonaminés, d'esters d'acide aminé, d'amides d'acide aminé et carbonitrile ou leurs sels pour l'augmentation de la tolérance au stress dans des plantes
|
US20130331378A1
(en)
|
2011-01-26 |
2013-12-12 |
Kissei Pharmaceutical Co., Ltd. |
Pyrazolopyridine derivative or pharmacologically acceptable salt thereof
|
EP2675789A1
(fr)
|
2011-02-17 |
2013-12-25 |
Bayer Intellectual Property GmbH |
3-(biphényle-3-yl)-8,8-difluoro-4-hydroxy-1-azaspiro[4,5]dec-3-en-2-ones substituées pour la thérapie et des cétoénols spirocycliques substitués par des halogènes
|
CA2828639C
(fr)
|
2011-03-01 |
2019-02-12 |
Bayer Intellectual Property Gmbh |
2-acyloxy-pyrrolin-4-ones
|
AR085585A1
(es)
|
2011-04-15 |
2013-10-09 |
Bayer Cropscience Ag |
Vinil- y alquinilciclohexanoles sustituidos como principios activos contra estres abiotico de plantas
|
WO2012166415A1
(fr)
|
2011-05-27 |
2012-12-06 |
Amira Pharmaceuticals, Inc. |
Inhibiteurs hétérocycliques d'autotaxine et leurs utilisations
|
US9428464B2
(en)
|
2011-08-30 |
2016-08-30 |
Chdi Foundation, Inc. |
Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
|
WO2013038373A1
(fr)
|
2011-09-16 |
2013-03-21 |
Novartis Ag |
Dérivés pyrimidinamides
|
JP6138797B2
(ja)
|
2011-09-16 |
2017-05-31 |
バイエル・インテレクチュアル・プロパティ・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツングBayer Intellectual Property GmbH |
植物収量を向上させるためのアシルスルホンアミド類の使用
|
JP2014527973A
(ja)
|
2011-09-23 |
2014-10-23 |
バイエル・インテレクチユアル・プロパテイー・ゲー・エム・ベー・ハー |
非生物的な植物ストレスに対する作用剤としての4−置換1−フェニルピラゾール−3−カルボン酸誘導体の使用
|
RU2640420C2
(ru)
|
2011-11-08 |
2018-01-09 |
Вертекс Фармасьютикалз Инкорпорейтед |
Модуляторы транспортеров атф-связывающей кассеты
|
US8426450B1
(en)
|
2011-11-29 |
2013-04-23 |
Helsinn Healthcare Sa |
Substituted 4-phenyl pyridines having anti-emetic effect
|
SI2806859T1
(sl)
|
2012-01-25 |
2019-11-29 |
Vertex Pharma |
Formulacije 3-(6-(1-(2.2-difluorobenzo(d)(1,3)dioksol-5-il) ciklopropankarboksamido)-3-metilpiridin-2-il)benzojske kisline
|
JP2015083542A
(ja)
|
2012-02-08 |
2015-04-30 |
大日本住友製薬株式会社 |
3位置換プロリン誘導体
|
IL265430B1
(en)
|
2012-02-27 |
2024-04-01 |
Vertex Pharma |
Pharmaceutical preparations containing a solid dispersion of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide and uses thereof
|
US8889730B2
(en)
|
2012-04-10 |
2014-11-18 |
Pfizer Inc. |
Indole and indazole compounds that activate AMPK
|
CA2869847A1
(fr)
|
2012-04-20 |
2013-10-24 |
Vertex Pharmaceuticals Incorporated |
Formes solides de n-[2,4-bis(1,1-dimethylethyle)-5-hydroxyphenyle]-1,4-dihydro-4-oxoquinoline-3-carboxamide
|
MX2014014234A
(es)
|
2012-05-22 |
2015-05-07 |
Genentech Inc |
Benzamidas n-sustituidas y su uso en el tratamiento del dolor.
|
CA2874851A1
(fr)
|
2012-06-08 |
2013-12-12 |
Vertex Pharmaceuticals Incorporated |
Compositions pharmaceutiques pour le traitement des troubles a mediation par cftr
|
WO2013185202A1
(fr)
|
2012-06-14 |
2013-12-19 |
Beta Pharma Canada Inc |
Inducteurs d'apoptose
|
KR101663436B1
(ko)
|
2012-07-06 |
2016-10-06 |
제넨테크, 인크. |
N-치환된 벤즈아미드 및 이의 사용 방법
|
AU2013290444B2
(en)
|
2012-07-16 |
2018-04-26 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions of (R)-1-(2,2-diflurorbenzo[d][1,3]dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl) cyclopropanecarboxamide and administration thereof
|
JP2015178458A
(ja)
|
2012-07-25 |
2015-10-08 |
杏林製薬株式会社 |
ベンゼン環縮合含窒素5員複素環式化合物、またはその薬理学的に許容される塩
|
CN103571906B
(zh)
|
2012-07-27 |
2018-12-11 |
上海泽元海洋生物技术有限公司 |
一种利用微藻高效生产虾青素的新方法
|
MX360172B
(es)
|
2012-08-13 |
2018-10-12 |
Abbvie Inc |
Agentes que inducen la apoptosis.
|
CA2881357C
(fr)
|
2012-08-21 |
2020-12-08 |
Peter Maccallum Cancer Institute |
Composes de benzenesulfonamide inhibiteurs de la perforine, leur preparation et leurs utilisations
|
US10227357B2
(en)
|
2012-09-06 |
2019-03-12 |
Plexxikon Inc. |
Compounds and methods for kinase modulation, and indications therefor
|
US10093640B2
(en)
|
2012-09-21 |
2018-10-09 |
Vanderbilt University |
Substituted benzofuran, benzothiophene and indole MCL-1 inhibitors
|
EP2914248B2
(fr)
|
2012-11-02 |
2023-10-18 |
Vertex Pharmaceuticals Incorporated |
Compositions pharmaceutiques pour le traitement de maladies médiées par cftr
|
WO2014071247A1
(fr)
|
2012-11-02 |
2014-05-08 |
Dana-Farber Cancer Institute, Inc. |
Dérivés d'acide pyrrol-1-yl-benzoïque utiles en tant qu'inhibiteurs de myc
|
EP2914265A4
(fr)
|
2012-11-05 |
2016-04-13 |
Nant Holdings Ip Llc |
Dérivés indol-5-ole substitués et leurs applications thérapeutiques
|
JP2016500368A
(ja)
|
2012-12-05 |
2016-01-12 |
バイエル・クロップサイエンス・アクチェンゲゼルシャフト |
置換された1−(アリールエチニル)−、1−(ヘテロアリールエチニル)−、1−(複素環エチニル)−および1−(シクロアルケニルエチニル)−シクロヘキサノールの非生物的植物ストレスに対する活性薬剤としての使用
|
JP2016504300A
(ja)
|
2012-12-05 |
2016-02-12 |
バイエル・クロップサイエンス・アクチェンゲゼルシャフト |
置換された1−(アリールエチニル)−、1−(ヘテロアリールエチニル)−、1−(複素環エチニル)−および1−(シクロアルケニルエチニル)ビシクロアルカノールの非生物的植物ストレスに対する活性薬剤としての使用
|
UA115576C2
(uk)
|
2012-12-06 |
2017-11-27 |
Байєр Фарма Акцієнгезелльшафт |
Похідні бензимідазолу як антагоністи ер4
|
GB201223265D0
(en)
|
2012-12-21 |
2013-02-06 |
Selvita Sa |
Novel benzimidazole derivatives as kinase inhibitors
|
WO2014109858A1
(fr)
|
2013-01-14 |
2014-07-17 |
Amgen Inc. |
Méthodes d'utilisation d'inhibiteurs de cycle cellulaire pour moduler une ou plusieurs propriétés d'une culture cellulaire
|
US9637450B2
(en)
|
2013-03-14 |
2017-05-02 |
The Trustees Of Columbia University In The City Of New York |
Octahydrocyclopentapyrroles, their preparation and use
|
EP2968304B1
(fr)
|
2013-03-14 |
2018-10-10 |
The Trustees of Columbia University in the City of New York |
4-phénylpipéridines, leur préparation et leur utilisation
|
ES2911276T3
(es)
|
2013-03-15 |
2022-05-18 |
Cyclerion Therapeutics Inc |
Estimuladores de sGC
|
CN105492433B
(zh)
|
2013-03-29 |
2018-11-23 |
武田药品工业株式会社 |
6-(5-羟基-1h-吡唑-1-基)烟碱酰胺衍生物和其作为phd抑制剂的用途
|
AU2014264936B2
(en)
|
2013-05-07 |
2018-09-27 |
Galapagos Nv |
Novel compounds and pharmaceutical compositions thereof for the treatment of cystic fibrosis
|
WO2014181287A1
(fr)
|
2013-05-09 |
2014-11-13 |
Piramal Enterprises Limited |
Composés hétérocyclyliques et leurs utilisations
|
WO2014190199A1
(fr)
|
2013-05-24 |
2014-11-27 |
The California Institute For Biomedical Research |
Composés pour le traitement de la tuberculose résistante aux médicaments et persistante
|
WO2015010832A1
(fr)
|
2013-07-22 |
2015-01-29 |
Syngenta Participations Ag |
Dérivés hétérocycliques microbiocides
|
WO2015031608A1
(fr)
|
2013-08-28 |
2015-03-05 |
Vanderbilt University |
Inhibiteurs de mcl-1 de type indole substitué
|
US9663508B2
(en)
|
2013-10-01 |
2017-05-30 |
Amgen Inc. |
Biaryl acyl-sulfonamide compounds as sodium channel inhibitors
|
WO2015069287A1
(fr)
|
2013-11-08 |
2015-05-14 |
Allergan, Inc. |
Composés à utiliser en tant que modulateurs des tyrosine kinases
|
ES2865600T3
(es)
|
2013-11-12 |
2021-10-15 |
Vertex Pharma |
Proceso de preparación de composiciones farmacéuticas para el tratamiento de enfermedades mediadas por CFTR
|
WO2015160787A1
(fr)
|
2014-04-15 |
2015-10-22 |
Vertex Pharmaceuticals Incorporated |
Compositions pharmaceutiques destinées au traitement des maladies liées au régulateur de la conductance transmembranaire de la mucoviscidose
|
CN112279808B
(zh)
*
|
2014-10-06 |
2024-03-08 |
弗特克斯药品有限公司 |
囊性纤维化跨膜转导调节因子调节剂
|
CN107250113B
(zh)
|
2014-10-07 |
2019-03-29 |
弗特克斯药品有限公司 |
囊性纤维化跨膜传导调节蛋白的调节剂的共晶
|
JP6494757B2
(ja)
|
2014-11-18 |
2019-04-03 |
バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated |
ハイスループット試験高速液体クロマトグラフィーを行うプロセス
|
CA2971855A1
(fr)
|
2014-12-23 |
2016-06-30 |
Proteostasis Therapeutics, Inc. |
Derives d'amide 5-(hetero)arylpyrazol-3-carboxylique ou d'amide 1-(hetero)aryltriazol-4-carboxylique utiles pour le traitement, entre autres, de la fibrose kystique
|
MA41253A
(fr)
|
2014-12-23 |
2017-10-31 |
Proteostasis Therapeutics Inc |
Composés, compositions et procédés pour augmenter l'activité du cftr
|
JP6700291B2
(ja)
|
2015-02-15 |
2020-05-27 |
エフ.ホフマン−ラ ロシュ アーゲーF. Hoffmann−La Roche Aktiengesellschaft |
1−(het)アリールスルホニル−(ピロリジン又はピペリジン)−2−カルボキサミド誘導体、及びtrpa1拮抗薬としてのそれらの使用
|
CA2981495C
(fr)
|
2015-03-31 |
2023-09-26 |
Vertex Pharmaceuticals (Europe) Limited |
Vx-661 deutere
|
US20180353500A1
(en)
|
2015-09-21 |
2018-12-13 |
Vertex Pharmaceuticals (Europe) Limited |
Administration of deuterated cftr potentiators
|
EP3436432B1
(fr)
|
2016-03-30 |
2021-01-27 |
Genentech, Inc. |
Benzamides substitués et leurs méthodes d'utilisation
|
WO2017173274A1
(fr)
|
2016-03-31 |
2017-10-05 |
Vertex Pharmaceuticals Incorporated |
Modulateurs du régulateur de la conductance transmembranaire de la fibrose kystique
|
NZ746793A
(en)
|
2016-04-07 |
2022-10-28 |
Proteostasis Therapeutics Inc |
Silicone atoms containing ivacaftor analogues
|
EP3448842A1
(fr)
|
2016-04-26 |
2019-03-06 |
AbbVie S.À.R.L. |
Modulateurs de protéine régulatrice de conductance transmembranaire de la fibrose kystique
|
US10138227B2
(en)
|
2016-06-03 |
2018-11-27 |
Abbvie S.Á.R.L. |
Heteroaryl substituted pyridines and methods of use
|
MA45397A
(fr)
|
2016-06-21 |
2019-04-24 |
Proteostasis Therapeutics Inc |
Composés, compositions et procédés pour augmenter l'activité du cftr
|
PE20191147A1
(es)
*
|
2016-09-30 |
2019-09-02 |
Vertex Pharma |
Modulador de regulador de conductancia de transmembrana de fibrosis quistica, composiciones farmaceuticas, metodos de tratamiento y proceso para producir el modulador
|
US10399940B2
(en)
|
2016-10-07 |
2019-09-03 |
Abbvie S.Á.R.L. |
Substituted pyrrolidines and methods of use
|
US9981910B2
(en)
|
2016-10-07 |
2018-05-29 |
Abbvie S.Á.R.L. |
Substituted pyrrolidines and methods of use
|
AU2017348182A1
(en)
|
2016-10-26 |
2019-05-16 |
Proteostasis Therapeutics, Inc. |
N-phenyl-2-(3-phenyl-6-oxo-1,6-dihydropyridazin-1-yl)acetamide derivatives for treating cystic fibrosis
|
AU2017348183A1
(en)
|
2016-10-26 |
2019-05-16 |
Proteostasis Therapeutics, Inc. |
Compounds, compositions, and methods for modulating CFTR
|
EP3532467A1
(fr)
|
2016-10-26 |
2019-09-04 |
Proteostasis Therapeutics, Inc. |
Composés de pyridazine, compositions et méthodes permettant de moduler cftr
|
CN110337294B
(zh)
|
2016-11-18 |
2022-11-01 |
囊性纤维化基金会 |
作为cftr增效剂的吡咯并嘧啶
|
UY37513A
(es)
|
2016-12-09 |
2018-07-31 |
Vertex Pharma |
Modulador del regulador de conductancia transmembrana de fibrosis quística, composiciones farmacéuticas, métodos de tratamiento y proceso para producir el modulador
|
SG10201911076QA
(en)
|
2016-12-16 |
2020-01-30 |
Cystic Fibrosis Found |
Bycyclic heteroaryl derivatives as cftr potentiators
|
WO2018116185A1
(fr)
|
2016-12-20 |
2018-06-28 |
AbbVie S.à.r.l. |
Modulateurs cftr deutérés et procédés d'utilisation
|
EP3565815B1
(fr)
|
2017-01-07 |
2024-03-13 |
Fochon Pharmaceuticals, Ltd. |
Composés en tant qu'agents induisant l'apoptose sélective de bcl-2
|
TW201831471A
(zh)
|
2017-02-24 |
2018-09-01 |
盧森堡商艾伯維公司 |
囊腫纖化症跨膜傳導調節蛋白的調節劑及其使用方法
|
US20180280349A1
(en)
|
2017-03-28 |
2018-10-04 |
Vertex Pharmaceuticals Incorporated |
Methods of treating cystic fibrosis in patients with residual function mutations
|
CA3061476A1
(fr)
|
2017-04-28 |
2018-11-01 |
Proteostasis Therapeutics, Inc. |
Derives de 4-sulfonylaminocarbonylquinoleine pour accroitre l'activite du cftr
|
BR112019025801A2
(pt)
|
2017-06-08 |
2020-07-07 |
Vertex Pharmaceuticals Incorporated |
métodos de tratamento para fibrose cística
|
US20210069174A1
(en)
|
2017-07-01 |
2021-03-11 |
Vertex Pharmaceuticals Incorporated |
Compositions and methods for treatment of cystic fibrosis
|
WO2019018353A1
(fr)
|
2017-07-17 |
2019-01-24 |
Vertex Pharmaceuticals Incorporated |
Méthodes de traitement de la fibrose kystique
|
EP3654969A1
(fr)
|
2017-07-17 |
2020-05-27 |
Vertex Pharmaceuticals Incorporated |
Méthodes de traitement de la fibrose kystique
|
US11427858B2
(en)
|
2017-07-31 |
2022-08-30 |
Technion Research & Development Foundation Limited |
Methods of detecting modified and unmodified DNA
|
AU2018309043B2
(en)
|
2017-08-02 |
2022-03-31 |
Vertex Pharmaceuticals Incorporated |
Processes for preparing pyrrolidine compounds
|
US10988454B2
(en)
|
2017-09-14 |
2021-04-27 |
Abbvie Overseas S.À.R.L. |
Modulators of the cystic fibrosis transmembrane conductance regulator protein and methods of use
|
US20210369749A1
(en)
|
2017-10-06 |
2021-12-02 |
Proteostasis Therapeutics, Inc. |
Compounds, compositions, and methods for increasing cftr activity
|
WO2019079760A1
(fr)
|
2017-10-19 |
2019-04-25 |
Vertex Pharmaceuticals Incorporated |
Formes cristallines et compositions de modulateurs de cftr
|
US20210228489A1
(en)
|
2017-12-04 |
2021-07-29 |
Vertex Pharmaceuticals Incorporated |
Compositions for treating cystic fibrosis
|
KR20200097293A
(ko)
|
2017-12-08 |
2020-08-18 |
버텍스 파마슈티칼스 인코포레이티드 |
낭포성 섬유증 막횡단 전도 조절자의 조정제의 제조 방법
|
TWI810243B
(zh)
|
2018-02-05 |
2023-08-01 |
美商維泰克斯製藥公司 |
用於治療囊腫纖化症之醫藥組合物
|
WO2019191620A1
(fr)
|
2018-03-30 |
2019-10-03 |
Vertex Pharmaceuticals Incorporated |
Formes cristallines de modulateurs de cftr
|
US20210139514A1
(en)
|
2018-04-05 |
2021-05-13 |
Vertex Pharmaceuticals Incorporated |
Modulators of cystic fibrosis transmembrane conductance regulator
|
EP3774825A1
(fr)
|
2018-04-13 |
2021-02-17 |
Vertex Pharmaceuticals Incorporated |
Modulateurs du régulateur de la conductance transmembranaire de la fibrose kystique, compositions pharmaceutiques, procédés de traitement et procédé de fabrication du modulateur
|