MA37894B1 - Protéines de fusion d'interleukine-2 et leurs utilisations - Google Patents

Protéines de fusion d'interleukine-2 et leurs utilisations

Info

Publication number
MA37894B1
MA37894B1 MA37894A MA37894A MA37894B1 MA 37894 B1 MA37894 B1 MA 37894B1 MA 37894 A MA37894 A MA 37894A MA 37894 A MA37894 A MA 37894A MA 37894 B1 MA37894 B1 MA 37894B1
Authority
MA
Morocco
Prior art keywords
fusion proteins
interleukin
methods
present
relates
Prior art date
Application number
MA37894A
Other languages
English (en)
Other versions
MA37894A1 (fr
Inventor
Ralf Hosse
Ekkehard Moessner
Pablo Umana
Christian Klein
Laurence Bernard Peterson
Linda Wicker
Original Assignee
Roche Glycart Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48948417&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MA37894(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Roche Glycart Ag filed Critical Roche Glycart Ag
Publication of MA37894A1 publication Critical patent/MA37894A1/fr
Publication of MA37894B1 publication Critical patent/MA37894B1/fr

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/55IL-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • A61K38/2013IL-2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/46Hybrid immunoglobulins
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Transplantation (AREA)
  • Biomedical Technology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

La présente invention concerne en général des protéines de fusion d'immunoglobulines et d'interleukine-2 (il-2). De plus, la présente invention concerne des polynucléotides codant pour de telles protéines de fusion, et des vecteurs et cellules hôtes comprenant de tels polynucléotides. L'invention concerne en outre des procédés de production des protéines de fusion de l'invention, et leurs procédés d'utilisation dans le traitement d'une maladie.
MA37894A 2012-08-10 2013-08-07 Protéines de fusion d'interleukine-2 et leurs utilisations MA37894B1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261681676P 2012-08-10 2012-08-10
PCT/EP2013/066516 WO2014023752A1 (fr) 2012-08-10 2013-08-07 Protéines de fusion d'interleukine-2 et leurs utilisations

Publications (2)

Publication Number Publication Date
MA37894A1 MA37894A1 (fr) 2018-07-31
MA37894B1 true MA37894B1 (fr) 2020-01-31

Family

ID=48948417

Family Applications (1)

Application Number Title Priority Date Filing Date
MA37894A MA37894B1 (fr) 2012-08-10 2013-08-07 Protéines de fusion d'interleukine-2 et leurs utilisations

Country Status (22)

Country Link
US (4) US20140044675A1 (fr)
EP (1) EP2882458B1 (fr)
JP (1) JP6526561B2 (fr)
KR (1) KR20150041628A (fr)
CN (2) CN111635460A (fr)
AR (1) AR092089A1 (fr)
AU (1) AU2013301562B2 (fr)
BR (1) BR112015002765A2 (fr)
CA (1) CA2873291A1 (fr)
CL (1) CL2014003322A1 (fr)
CO (1) CO7121348A2 (fr)
CR (1) CR20140532A (fr)
EA (1) EA201500206A1 (fr)
HK (1) HK1208827A1 (fr)
IL (1) IL236933A0 (fr)
MA (1) MA37894B1 (fr)
MX (1) MX2015001749A (fr)
PE (1) PE20150752A1 (fr)
PH (1) PH12014502767A1 (fr)
SG (1) SG11201407579QA (fr)
TW (1) TW201420607A (fr)
WO (1) WO2014023752A1 (fr)

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JP2015530984A (ja) 2015-10-29
CA2873291A1 (fr) 2014-02-13
CO7121348A2 (es) 2014-11-20
JP6526561B2 (ja) 2019-06-05
MX2015001749A (es) 2015-06-05
SG11201407579QA (en) 2014-12-30
US20140044675A1 (en) 2014-02-13
PH12014502767A1 (en) 2015-02-09
US20160090407A1 (en) 2016-03-31
CR20140532A (es) 2015-01-12
IL236933A0 (en) 2015-03-31
EP2882458A1 (fr) 2015-06-17
AU2013301562B2 (en) 2017-04-06
CL2014003322A1 (es) 2015-02-13
US20200172591A1 (en) 2020-06-04
EP2882458B1 (fr) 2018-07-11
BR112015002765A2 (pt) 2018-03-13
MA37894A1 (fr) 2018-07-31
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EA201500206A1 (ru) 2016-04-29
KR20150041628A (ko) 2015-04-16
PE20150752A1 (es) 2015-05-15
US20180009868A1 (en) 2018-01-11
HK1208827A1 (en) 2016-03-18
WO2014023752A1 (fr) 2014-02-13
US10562949B2 (en) 2020-02-18
CN111635460A (zh) 2020-09-08
CN104507504A (zh) 2015-04-08
AU2013301562A1 (en) 2014-11-20
AR092089A1 (es) 2015-03-25
US11365232B2 (en) 2022-06-21

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