BR112015002765A2 - proteína de fusão, polinucleotídeo, vetor, célula hospedeira, métodos para produzir a proteína de fusão, de tratamento de uma doença em um indivíduo e para ativação seletiva in vitro ou in vivo de células reguladoras, composição farmacêutica, uso da proteína de fusão e invenção. - Google Patents

proteína de fusão, polinucleotídeo, vetor, célula hospedeira, métodos para produzir a proteína de fusão, de tratamento de uma doença em um indivíduo e para ativação seletiva in vitro ou in vivo de células reguladoras, composição farmacêutica, uso da proteína de fusão e invenção.

Info

Publication number
BR112015002765A2
BR112015002765A2 BR112015002765A BR112015002765A BR112015002765A2 BR 112015002765 A2 BR112015002765 A2 BR 112015002765A2 BR 112015002765 A BR112015002765 A BR 112015002765A BR 112015002765 A BR112015002765 A BR 112015002765A BR 112015002765 A2 BR112015002765 A2 BR 112015002765A2
Authority
BR
Brazil
Prior art keywords
fusion protein
polynucleotide
vitro
selective
vector
Prior art date
Application number
BR112015002765A
Other languages
English (en)
Inventor
Klein Christian
Moessner Ekkehard
Bernard Peterson Laurence
Wicker Linda
Umana Pablo
Hosse Ralf
Original Assignee
Roche Glycart Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=48948417&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR112015002765(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Roche Glycart Ag filed Critical Roche Glycart Ag
Publication of BR112015002765A2 publication Critical patent/BR112015002765A2/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/55—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A61K38/2013—IL-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Emergency Medicine (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Transplantation (AREA)
  • Endocrinology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
BR112015002765A 2012-08-10 2013-08-07 proteína de fusão, polinucleotídeo, vetor, célula hospedeira, métodos para produzir a proteína de fusão, de tratamento de uma doença em um indivíduo e para ativação seletiva in vitro ou in vivo de células reguladoras, composição farmacêutica, uso da proteína de fusão e invenção. BR112015002765A2 (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261681676P 2012-08-10 2012-08-10
PCT/EP2013/066516 WO2014023752A1 (en) 2012-08-10 2013-08-07 Interleukin-2 fusion proteins and uses thereof

Publications (1)

Publication Number Publication Date
BR112015002765A2 true BR112015002765A2 (pt) 2018-03-13

Family

ID=48948417

Family Applications (1)

Application Number Title Priority Date Filing Date
BR112015002765A BR112015002765A2 (pt) 2012-08-10 2013-08-07 proteína de fusão, polinucleotídeo, vetor, célula hospedeira, métodos para produzir a proteína de fusão, de tratamento de uma doença em um indivíduo e para ativação seletiva in vitro ou in vivo de células reguladoras, composição farmacêutica, uso da proteína de fusão e invenção.

Country Status (22)

Country Link
US (4) US20140044675A1 (pt)
EP (1) EP2882458B1 (pt)
JP (1) JP6526561B2 (pt)
KR (1) KR20150041628A (pt)
CN (2) CN111635460A (pt)
AR (1) AR092089A1 (pt)
AU (1) AU2013301562B2 (pt)
BR (1) BR112015002765A2 (pt)
CA (1) CA2873291A1 (pt)
CL (1) CL2014003322A1 (pt)
CO (1) CO7121348A2 (pt)
CR (1) CR20140532A (pt)
EA (1) EA201500206A1 (pt)
HK (1) HK1208827A1 (pt)
IL (1) IL236933A0 (pt)
MA (1) MA37894B1 (pt)
MX (1) MX2015001749A (pt)
PE (1) PE20150752A1 (pt)
PH (1) PH12014502767A1 (pt)
SG (1) SG11201407579QA (pt)
TW (1) TW201420607A (pt)
WO (1) WO2014023752A1 (pt)

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US20140044675A1 (en) 2012-08-10 2014-02-13 Roche Glycart Ag Interleukin-2 fusion proteins and uses thereof
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Also Published As

Publication number Publication date
CR20140532A (es) 2015-01-12
US20140044675A1 (en) 2014-02-13
CO7121348A2 (es) 2014-11-20
CN104507504A (zh) 2015-04-08
PE20150752A1 (es) 2015-05-15
US11365232B2 (en) 2022-06-21
US10562949B2 (en) 2020-02-18
KR20150041628A (ko) 2015-04-16
CA2873291A1 (en) 2014-02-13
HK1208827A1 (en) 2016-03-18
US20180009868A1 (en) 2018-01-11
US20200172591A1 (en) 2020-06-04
MA37894A1 (fr) 2018-07-31
US20160090407A1 (en) 2016-03-31
AR092089A1 (es) 2015-03-25
WO2014023752A1 (en) 2014-02-13
MX2015001749A (es) 2015-06-05
PH12014502767A1 (en) 2015-02-09
CL2014003322A1 (es) 2015-02-13
TW201420607A (zh) 2014-06-01
JP2015530984A (ja) 2015-10-29
EP2882458B1 (en) 2018-07-11
AU2013301562B2 (en) 2017-04-06
JP6526561B2 (ja) 2019-06-05
CN111635460A (zh) 2020-09-08
MA37894B1 (fr) 2020-01-31
EA201500206A1 (ru) 2016-04-29
SG11201407579QA (en) 2014-12-30
AU2013301562A1 (en) 2014-11-20
EP2882458A1 (en) 2015-06-17
IL236933A0 (en) 2015-03-31

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