LT3947B - Process for the preparation of 5-halogen-thienoisothiazol-3(2h)-on-1,1-dioxide containing basic substituents - Google Patents

Process for the preparation of 5-halogen-thienoisothiazol-3(2h)-on-1,1-dioxide containing basic substituents Download PDF

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Publication number
LT3947B
LT3947B LTIP1813A LTIP1813A LT3947B LT 3947 B LT3947 B LT 3947B LT IP1813 A LTIP1813 A LT IP1813A LT IP1813 A LTIP1813 A LT IP1813A LT 3947 B LT3947 B LT 3947B
Authority
LT
Lithuania
Prior art keywords
formula
halogen
compounds
compound
acid
Prior art date
Application number
LTIP1813A
Other languages
English (en)
Lithuanian (lt)
Inventor
Dieter Binder
Franz Rovenszky
Original Assignee
Chem Pharm Forsch Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chem Pharm Forsch Gmbh filed Critical Chem Pharm Forsch Gmbh
Publication of LTIP1813A publication Critical patent/LTIP1813A/xx
Publication of LT3947B publication Critical patent/LT3947B/lt

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
LTIP1813A 1988-02-18 1994-01-27 Process for the preparation of 5-halogen-thienoisothiazol-3(2h)-on-1,1-dioxide containing basic substituents LT3947B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT88390A ATA39088A (de) 1988-02-18 1988-02-18 Basisch substituierte thienoisothiazol-3(2h)-on-1,1-dioxide und ihre pharmazeutisch vertraeglichen salze, verfahren zu ihrer herstellung und ihre verwendung

Publications (2)

Publication Number Publication Date
LTIP1813A LTIP1813A (en) 1995-08-25
LT3947B true LT3947B (en) 1996-05-27

Family

ID=3489327

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP1813A LT3947B (en) 1988-02-18 1994-01-27 Process for the preparation of 5-halogen-thienoisothiazol-3(2h)-on-1,1-dioxide containing basic substituents

Country Status (28)

Country Link
US (1) US4929616A (zh)
EP (1) EP0328913B1 (zh)
JP (1) JPH01249779A (zh)
KR (1) KR890013033A (zh)
CN (1) CN1024798C (zh)
AT (2) ATA39088A (zh)
AU (1) AU618577B2 (zh)
CA (1) CA1317956C (zh)
CS (1) CS274578B2 (zh)
DD (1) DD279021A5 (zh)
DE (1) DE58907804D1 (zh)
DK (1) DK170047B1 (zh)
EG (1) EG20261A (zh)
ES (1) ES2054887T3 (zh)
FI (1) FI89491C (zh)
HR (1) HRP940825A2 (zh)
HU (1) HU201084B (zh)
IL (1) IL89185A (zh)
LT (1) LT3947B (zh)
MY (1) MY103825A (zh)
NO (1) NO176050C (zh)
NZ (1) NZ227939A (zh)
PH (1) PH26156A (zh)
SI (1) SI8910358A (zh)
SU (1) SU1729293A3 (zh)
UA (1) UA13481A (zh)
YU (1) YU35889A (zh)
ZA (1) ZA891108B (zh)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0376633B1 (en) * 1988-12-28 1994-10-12 Suntory Limited Benzoxazepine derivatives
CA2567813C (en) 2004-05-23 2015-11-24 Gerard M. Housey Theramutein modulators
US8431110B2 (en) 2005-05-23 2013-04-30 Hmi Medical Innovations, Llc. Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators
CN103789389B (zh) * 2005-11-23 2017-01-04 杰勒德·M·豪斯 鉴定、合成、优化和表征蛋白调节剂的化合物和方法
CN101186612B (zh) * 2006-11-15 2012-10-03 天津和美生物技术有限公司 可抑制细胞释放肿瘤坏死因子的吡咯啉衍生物及其制备和应用
US8551560B2 (en) * 2008-05-23 2013-10-08 Intermolecular, Inc. Methods for improving selectivity of electroless deposition processes

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2537070A1 (de) 1974-08-26 1976-03-18 Hoffmann La Roche Thiazinderivate
DE2534689A1 (de) 1974-09-16 1976-03-25 Basf Ag Thiophensaccharine
DE2835760A1 (de) 1977-08-22 1979-03-08 Hoffmann La Roche Thiazinderivate
DE2838851A1 (de) 1977-09-06 1979-03-22 Hoffmann La Roche Thiazinderivate
DE2749640A1 (de) 1977-11-05 1979-05-10 Thomae Gmbh Dr K Ein thieno eckige klammer auf 3,2-d eckige klammer zu isothiazolondioxid, verfahren zu seiner herstellung und dessen verwendung
DE2839266A1 (de) 1978-09-09 1980-03-20 Thomae Gmbh Dr K Kondensierte isothiazol-3(2h)-on-1,1- dioxide, verfahren zu deren herstellung und deren verwendung
EP0103142A1 (de) 1982-09-09 1984-03-21 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Thieno(2,3-e)-1,2-thiazin-Derivate
EP0220051A1 (en) 1985-10-17 1987-04-29 American Home Products Corporation Isothiazolone derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT364852B (de) * 1977-11-05 1981-11-25 Thomae Gmbh Dr K Verfahren zur herstellung von kondensierten isothiazol-3(2h)-on-1,1-dioxiden und von deren salzen
DE3321969A1 (de) * 1983-06-18 1984-12-20 Troponwerke GmbH & Co KG, 5000 Köln 2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
FI862513A (fi) * 1985-07-04 1987-01-05 Chemie Linz Ag Nya tieno-1,2-tiazolderivat, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska preparat.
US4675403A (en) * 1985-10-16 1987-06-23 American Home Products Corporation 3-Aminoalkyl derivatives of 5,5-disubstituted hydantoins with psychotropic activity

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2537070A1 (de) 1974-08-26 1976-03-18 Hoffmann La Roche Thiazinderivate
DE2534689A1 (de) 1974-09-16 1976-03-25 Basf Ag Thiophensaccharine
DE2835760A1 (de) 1977-08-22 1979-03-08 Hoffmann La Roche Thiazinderivate
DE2838851A1 (de) 1977-09-06 1979-03-22 Hoffmann La Roche Thiazinderivate
DE2749640A1 (de) 1977-11-05 1979-05-10 Thomae Gmbh Dr K Ein thieno eckige klammer auf 3,2-d eckige klammer zu isothiazolondioxid, verfahren zu seiner herstellung und dessen verwendung
DE2839266A1 (de) 1978-09-09 1980-03-20 Thomae Gmbh Dr K Kondensierte isothiazol-3(2h)-on-1,1- dioxide, verfahren zu deren herstellung und deren verwendung
EP0103142A1 (de) 1982-09-09 1984-03-21 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Thieno(2,3-e)-1,2-thiazin-Derivate
EP0220051A1 (en) 1985-10-17 1987-04-29 American Home Products Corporation Isothiazolone derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
K. L. HOWARD, H. W. STEWART, E. A. CONROY, J.: "Piperazines. II. 1-Heterocyclicpiperazines and 1-Hetero-Cyclic-4-Carbethoxypiperazines", J. ORG. CHEM, 1953, pages 1484

Also Published As

Publication number Publication date
CN1024798C (zh) 1994-06-01
CS274578B2 (en) 1991-08-13
AU2994589A (en) 1989-08-24
PH26156A (en) 1992-03-18
ATA39088A (de) 1990-06-15
IL89185A (en) 1992-08-18
DD279021A5 (de) 1990-05-23
NZ227939A (en) 1991-02-26
EP0328913A2 (de) 1989-08-23
HUT50839A (en) 1990-03-28
FI890690A0 (fi) 1989-02-14
DK170047B1 (da) 1995-05-08
DK73289A (da) 1989-10-11
SI8910358A (sl) 1997-02-28
FI890690A (fi) 1989-08-19
CA1317956C (en) 1993-05-18
FI89491B (fi) 1993-06-30
KR890013033A (ko) 1989-09-21
SU1729293A3 (ru) 1992-04-23
NO890691D0 (no) 1989-02-17
JPH01249779A (ja) 1989-10-05
UA13481A (uk) 1997-04-25
ATE106888T1 (de) 1994-06-15
CS93189A2 (en) 1990-10-12
HRP940825A2 (en) 1996-04-30
DE58907804D1 (de) 1994-07-14
EP0328913B1 (de) 1994-06-08
LTIP1813A (en) 1995-08-25
YU35889A (en) 1990-06-30
NO176050C (no) 1995-01-25
CN1038646A (zh) 1990-01-10
AU618577B2 (en) 1992-01-02
EP0328913A3 (de) 1991-01-23
ES2054887T3 (es) 1994-08-16
MY103825A (en) 1993-09-30
NO176050B (no) 1994-10-17
ZA891108B (en) 1989-10-25
NO890691L (no) 1989-08-21
DK73289D0 (da) 1989-02-17
FI89491C (fi) 1993-10-11
EG20261A (en) 1998-05-31
HU201084B (en) 1990-09-28
IL89185A0 (en) 1989-09-10
US4929616A (en) 1990-05-29

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Effective date: 19980127