ES2054887T3 - Nuevos 5-halogeno-tienoisotiazol-3(2h)-on-1,1-dioxidos basicamente substituidos, un procedimiento para su obtencion y los preparados farmaceuticos que contienen estos compuestos. - Google Patents

Nuevos 5-halogeno-tienoisotiazol-3(2h)-on-1,1-dioxidos basicamente substituidos, un procedimiento para su obtencion y los preparados farmaceuticos que contienen estos compuestos.

Info

Publication number
ES2054887T3
ES2054887T3 ES89101335T ES89101335T ES2054887T3 ES 2054887 T3 ES2054887 T3 ES 2054887T3 ES 89101335 T ES89101335 T ES 89101335T ES 89101335 T ES89101335 T ES 89101335T ES 2054887 T3 ES2054887 T3 ES 2054887T3
Authority
ES
Spain
Prior art keywords
halogen
dioxides
thenoisotiazole
compounds
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89101335T
Other languages
English (en)
Inventor
Dieter Dr Binder
Franz Dipl-Ing Dr Rovenszky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CHEM PHARM FORSCH GmbH
Original Assignee
CHEM PHARM FORSCH GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CHEM PHARM FORSCH GmbH filed Critical CHEM PHARM FORSCH GmbH
Application granted granted Critical
Publication of ES2054887T3 publication Critical patent/ES2054887T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A NUEVOS 5 - HALOGENO - TIENOISOTIAZOL 3(2H) - ON - 1,1 - DIOXIDOS SUSTITUIDOS BASICAMENTE, DE FORMULA I, DONDE R1 ES HIDROGENO, (C1 - C4) -ALQUILO O HALOGENO, R2 ES HALOGENO Y N ES UN NUMERO ENTERO ENTRE 2 Y 6. TAMBIEN SE REFIERE A SUS SALES DE ADICION ACIDA FARMACEUTICAMENTE COMPATIBLES, A UN PROCESO PARA SU OBTENCION ASI COMO A SU APLICACION EN MEDICAMENTOS PARA EL TRATAMIENTO DE ESTADOS DE ANSIEDAD.
ES89101335T 1988-02-18 1989-01-26 Nuevos 5-halogeno-tienoisotiazol-3(2h)-on-1,1-dioxidos basicamente substituidos, un procedimiento para su obtencion y los preparados farmaceuticos que contienen estos compuestos. Expired - Lifetime ES2054887T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AT88390A ATA39088A (de) 1988-02-18 1988-02-18 Basisch substituierte thienoisothiazol-3(2h)-on-1,1-dioxide und ihre pharmazeutisch vertraeglichen salze, verfahren zu ihrer herstellung und ihre verwendung

Publications (1)

Publication Number Publication Date
ES2054887T3 true ES2054887T3 (es) 1994-08-16

Family

ID=3489327

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89101335T Expired - Lifetime ES2054887T3 (es) 1988-02-18 1989-01-26 Nuevos 5-halogeno-tienoisotiazol-3(2h)-on-1,1-dioxidos basicamente substituidos, un procedimiento para su obtencion y los preparados farmaceuticos que contienen estos compuestos.

Country Status (28)

Country Link
US (1) US4929616A (es)
EP (1) EP0328913B1 (es)
JP (1) JPH01249779A (es)
KR (1) KR890013033A (es)
CN (1) CN1024798C (es)
AT (2) ATA39088A (es)
AU (1) AU618577B2 (es)
CA (1) CA1317956C (es)
CS (1) CS274578B2 (es)
DD (1) DD279021A5 (es)
DE (1) DE58907804D1 (es)
DK (1) DK170047B1 (es)
EG (1) EG20261A (es)
ES (1) ES2054887T3 (es)
FI (1) FI89491C (es)
HR (1) HRP940825A2 (es)
HU (1) HU201084B (es)
IL (1) IL89185A (es)
LT (1) LT3947B (es)
MY (1) MY103825A (es)
NO (1) NO176050C (es)
NZ (1) NZ227939A (es)
PH (1) PH26156A (es)
SI (1) SI8910358A (es)
SU (1) SU1729293A3 (es)
UA (1) UA13481A (es)
YU (1) YU35889A (es)
ZA (1) ZA891108B (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE112769T1 (de) * 1988-12-28 1994-10-15 Suntory Ltd Benzoxazepinderivate.
CN106434833A (zh) 2004-05-23 2017-02-22 杰勒德·M·豪斯 Theramutein调节剂
US8431110B2 (en) 2005-05-23 2013-04-30 Hmi Medical Innovations, Llc. Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators
US20090275070A1 (en) * 2005-11-23 2009-11-05 Housey Gerard M Compounds and Methods of Identifying, Synthesizing, Optimizing and Profiling Protein Modulators
CN101186612B (zh) * 2006-11-15 2012-10-03 天津和美生物技术有限公司 可抑制细胞释放肿瘤坏死因子的吡咯啉衍生物及其制备和应用
US8551560B2 (en) * 2008-05-23 2013-10-08 Intermolecular, Inc. Methods for improving selectivity of electroless deposition processes

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL47877A (en) 1974-08-26 1978-10-31 Sparamedica Ag Thienothiazine carboxamide derivatives,their manufacture and pharmaceutical compositions containing them
DE2534689B2 (de) 1974-09-16 1979-03-01 Basf Ag, 6700 Ludwigshafen 23-Dihydro-3-oxo-thieno-isothiazol-1,1-dioxide
LU78009A1 (de) 1977-08-22 1979-05-23 Hoffmann La Roche Verfahren zur herstellung von thiazinderivaten
AU518216B2 (en) 1977-09-06 1981-09-17 Hafslund Nycomed Pharma Aktiengesellschaft Thienothiazine derivatives
DE2749640A1 (de) 1977-11-05 1979-05-10 Thomae Gmbh Dr K Ein thieno eckige klammer auf 3,2-d eckige klammer zu isothiazolondioxid, verfahren zu seiner herstellung und dessen verwendung
AT364852B (de) * 1977-11-05 1981-11-25 Thomae Gmbh Dr K Verfahren zur herstellung von kondensierten isothiazol-3(2h)-on-1,1-dioxiden und von deren salzen
DE2839266A1 (de) 1978-09-09 1980-03-20 Thomae Gmbh Dr K Kondensierte isothiazol-3(2h)-on-1,1- dioxide, verfahren zu deren herstellung und deren verwendung
EP0103142B1 (de) 1982-09-09 1987-04-22 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Thieno(2,3-e)-1,2-thiazin-Derivate
DE3321969A1 (de) * 1983-06-18 1984-12-20 Troponwerke GmbH & Co KG, 5000 Köln 2-pyrimidinyl-1-piperazin-derivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
FI862513A (fi) * 1985-07-04 1987-01-05 Chemie Linz Ag Nya tieno-1,2-tiazolderivat, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska preparat.
US4675403A (en) * 1985-10-16 1987-06-23 American Home Products Corporation 3-Aminoalkyl derivatives of 5,5-disubstituted hydantoins with psychotropic activity
US4732984A (en) * 1985-10-17 1988-03-22 American Home Products Corporation Piperazinoisothiazolones with psychotropic activity

Also Published As

Publication number Publication date
CN1038646A (zh) 1990-01-10
CS274578B2 (en) 1991-08-13
DK73289A (da) 1989-10-11
LTIP1813A (en) 1995-08-25
SI8910358A (sl) 1997-02-28
IL89185A0 (en) 1989-09-10
NO176050B (no) 1994-10-17
EP0328913A3 (de) 1991-01-23
NO890691D0 (no) 1989-02-17
HUT50839A (en) 1990-03-28
FI890690A (fi) 1989-08-19
HU201084B (en) 1990-09-28
US4929616A (en) 1990-05-29
IL89185A (en) 1992-08-18
FI89491B (fi) 1993-06-30
YU35889A (en) 1990-06-30
JPH01249779A (ja) 1989-10-05
DK73289D0 (da) 1989-02-17
MY103825A (en) 1993-09-30
FI89491C (fi) 1993-10-11
EG20261A (en) 1998-05-31
AU2994589A (en) 1989-08-24
FI890690A0 (fi) 1989-02-14
ATE106888T1 (de) 1994-06-15
NO890691L (no) 1989-08-21
DD279021A5 (de) 1990-05-23
DK170047B1 (da) 1995-05-08
UA13481A (uk) 1997-04-25
CA1317956C (en) 1993-05-18
NZ227939A (en) 1991-02-26
ATA39088A (de) 1990-06-15
SU1729293A3 (ru) 1992-04-23
ZA891108B (en) 1989-10-25
HRP940825A2 (en) 1996-04-30
DE58907804D1 (de) 1994-07-14
EP0328913B1 (de) 1994-06-08
AU618577B2 (en) 1992-01-02
CS93189A2 (en) 1990-10-12
LT3947B (en) 1996-05-27
CN1024798C (zh) 1994-06-01
PH26156A (en) 1992-03-18
NO176050C (no) 1995-01-25
EP0328913A2 (de) 1989-08-23
KR890013033A (ko) 1989-09-21

Similar Documents

Publication Publication Date Title
NO149888C (no) Analogifremgangsmaate for fremstilling av terapeutisk aktive 2-substituerte-2`-hydroksyl-6,7-benzomorfaner og syreaddisjonssalter derav
ES2038623T3 (es) Procedimiento para preparar soluciones de oxazafosforinas con estabilidad mejorada.
ES554305A0 (es) Procedimiento para la fabricacion de derivados quinolilglicinamidas
SE8102220L (sv) Anvendning av substituerade derivat av 4-fenyl-4-oxo-2-butensyra sasom lekemedel
ES2054887T3 (es) Nuevos 5-halogeno-tienoisotiazol-3(2h)-on-1,1-dioxidos basicamente substituidos, un procedimiento para su obtencion y los preparados farmaceuticos que contienen estos compuestos.
SE8503055D0 (sv) Piperonylcarboxamido derivatives
ES2028838T3 (es) Procedimiento para la obtencion de nuevos derivados de 4,5-hidro-oxazoles.
DK408083A (da) Isoquinolinderivater, deres fremstilling og anvendelse
ATE11915T1 (de) Benzothiazolderivate, diese enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung.
ES2037770T3 (es) Procedimiento para la preparacion de intermediarios para la sintesis de fosfomicina.
SE8603589L (sv) Metylendioxifenantren- och stilbenderivat
ATE37368T1 (de) Benzothiazolon-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
ATE59647T1 (de) Isoxazolderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutischen praeparate.
SE7904543L (sv) Nya joniska bensen-polyjodidderivat for anvendning som kontrastmedel vid rontgenbehandling
GR861013B (en) Process for the preparation of triazole derivatives
ES2036219T3 (es) 2,2; 6,6-dietilen-3-oxo-17alfa-pren-4-en-21,17alfa-carbolactonas, procedimiento para su preparacion y preparados farmaceuticos que las contienen.
ES500108A0 (es) Procedimiento para preparar nuevas benzotiopirano (2,3-c)pi-ridinas

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 328913

Country of ref document: ES