ES2032016T3 - Un procedimiento para la produccion de las 13, 14-ceto-pgfs. - Google Patents

Un procedimiento para la produccion de las 13, 14-ceto-pgfs.

Info

Publication number
ES2032016T3
ES2032016T3 ES198888303931T ES88303931T ES2032016T3 ES 2032016 T3 ES2032016 T3 ES 2032016T3 ES 198888303931 T ES198888303931 T ES 198888303931T ES 88303931 T ES88303931 T ES 88303931T ES 2032016 T3 ES2032016 T3 ES 2032016T3
Authority
ES
Spain
Prior art keywords
pgfs
ceto
procedure
production
blood pressure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES198888303931T
Other languages
English (en)
Inventor
Ryuzo Ueno
Ryuji Ueno
Tomio Oda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ueno Seiyaku Oyo Kenkyujo KK
Original Assignee
Ueno Seiyaku Oyo Kenkyujo KK
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ueno Seiyaku Oyo Kenkyujo KK filed Critical Ueno Seiyaku Oyo Kenkyujo KK
Application granted granted Critical
Publication of ES2032016T3 publication Critical patent/ES2032016T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)

Abstract

LA PRESENTE INVENCION PROPORCIONA NUEVOS COMPUESTOS 13,14-DIHIDRO-15-CETO-PGF Y COMPUESTOS VASOPRESORES QUE LOS CONTIENEN, LOS CUALES ELEVAN LA PRESION SANGUINEA, SIN LOS EFECTOS INHERENTES AL USO DE PGF, TALES COMO DEPRESION EFIMERA DE LA PRESION SANGUINEA O CONTRACCION DE LA TRAQUEA O EL INTESTINO.
ES198888303931T 1987-04-30 1988-04-29 Un procedimiento para la produccion de las 13, 14-ceto-pgfs. Expired - Lifetime ES2032016T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10752987 1987-04-30
JP23589087 1987-09-18

Publications (1)

Publication Number Publication Date
ES2032016T3 true ES2032016T3 (es) 1993-01-01

Family

ID=26447552

Family Applications (1)

Application Number Title Priority Date Filing Date
ES198888303931T Expired - Lifetime ES2032016T3 (es) 1987-04-30 1988-04-29 Un procedimiento para la produccion de las 13, 14-ceto-pgfs.

Country Status (11)

Country Link
US (1) US5106869A (es)
EP (1) EP0289349B1 (es)
JP (1) JPH0667900B2 (es)
KR (1) KR930006202B1 (es)
AT (1) ATE72235T1 (es)
CA (1) CA1324129C (es)
DE (2) DE10399038I2 (es)
ES (1) ES2032016T3 (es)
GR (1) GR3003749T3 (es)
NL (1) NL300135I2 (es)
ZA (1) ZA886909B (es)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2052735T3 (es) * 1987-09-18 1994-07-16 R Tech Ueno Ltd Un metodo para producir un agente hipotensor ocular.
JP2597629B2 (ja) * 1988-02-26 1997-04-09 株式会社 上野製薬応用研究所 １３，１４−ジヒドロ−１５−ケトプロスタグランジン類の安定化
US5321128A (en) * 1988-09-06 1994-06-14 Kabi Pharmacia Ab Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
US6187813B1 (en) 1990-04-10 2001-02-13 Pharmacia & Upjohn Aktiebolag Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
WO1990002553A1 (en) 1988-09-06 1990-03-22 Pharmacia Ab Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
US5296504A (en) * 1988-09-06 1994-03-22 Kabi Pharmacia Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension
US5234954A (en) * 1989-07-27 1993-08-10 K.K. Ueno Seiyaku Oyo Kenkyujo Treatment of hyperlipidemia with 15-keto-prostaglandin compounds
DE69019431T2 (de) * 1989-07-27 1995-09-14 Ueno Seiyaku Oyo Kenkyujo Kk Verwendung von 15-Keto-Prostansäure-Derivaten zur Herstellung eines Medikaments für die Verbesserung der Ausscheidung des Kaliumions.
DE69018903T2 (de) * 1989-08-09 1995-08-24 Ueno Seiyaku Oyo Kenkyujo Kk Verwendung von Prostansäurederivaten zur Herstellung von Arzneimitteln zur Verbesserung der Ausscheidung von Nichtprotein in die Därme.
CA2027814C (en) * 1989-10-20 1996-07-30 Ryuji Ueno Treatment of hepatobiliary disease with 15-keto-prostaglandin compounds
US5256696A (en) * 1989-11-22 1993-10-26 Kabushikikaisha Ueno Seiyaku Oyo Kenkyujo Treatment of cardiac dysfunction with 15-ketoprostaglandin compounds
CA2030345C (en) * 1989-11-22 1998-12-08 Ryuji Ueno Use of 15-keto-prostaglandin compound for improvement of encephalic function
US5254588A (en) * 1989-11-22 1993-10-19 Kabushikikaisha Ueno Seiyaku Oyo Kenkyujo Treatment of pulmonary dysfunction with 15-ketoprostaglandin compounds
CA2039420C (en) * 1990-04-04 1996-12-10 Ryuji Ueno Treatment of cataract with 15-keto-prostaglandin compounds
CA2046069C (en) * 1990-07-10 2002-04-09 Ryuji Ueno Treatment of inflammatory diseases with 15-keto-prostaglandin compounds
EP0503887B1 (en) * 1991-03-14 1996-08-28 R-Tech Ueno Ltd. Promotion of wound-healing with 15-keto-prostaglandin compounds
CA2065889C (en) * 1991-10-02 2002-08-27 Tetsuya Sugiyama Increasing the choroidal blood flow
AU674038B2 (en) * 1992-10-13 1996-12-05 Alcon Laboratories, Inc. Combinations of prostaglandins and clonidine derivatives for the treatment of glaucoma
US6294563B1 (en) 1994-10-27 2001-09-25 Allergan Sales, Inc. Combinations of prostaglandins and brimonidine or derivatives thereof
HU223345B1 (hu) 1995-12-20 2004-08-30 Chinoin Gyógyszer és Vegyészeti Termékek Gyára Rt. Eljárás alfa, béta-telítetlen ketonok sztereoszelektív redukciójára
AU7680096A (en) * 1995-12-22 1997-07-17 Alcon Laboratories, Inc. Combinations of dp and fp type prostaglandins for lowering iop
US6770675B2 (en) 1997-03-17 2004-08-03 Novartis Ag Compositions and methods for reducing ocular hypertension
EP1012137B1 (en) * 1997-09-09 2002-11-06 The Procter & Gamble Company Aromatic c16-c20-substituted tetrahydro prostaglandins useful as fp agonists
TWI225398B (en) * 1999-07-14 2004-12-21 R Tech Ueno Ltd Composition for treatment of external secretion disorders
AU2603301A (en) 1999-12-22 2001-07-03 Alcon Universal Limited 6-keto prostaglandin F1alpha and analogs for treating dry eye
CN100425241C (zh) * 2002-08-29 2008-10-15 参天制药株式会社 由Rho激酶抑制剂和前列腺素类物质构成的青光眼治疗剂
TWI348386B (en) * 2003-08-12 2011-09-11 R Tech Ueno Ltd Composition and method for promoting hair growth
ES2431640T3 (es) 2003-08-21 2013-11-27 Sucampo Ag Composición oftálmica que comprende éster isopropílico de unoprostona y un agente de viscosidad
EP1681059B1 (en) 2003-11-07 2009-09-09 Senju Pharmaceutical Co., Ltd. Pharmaceutical composition containing prostaglandin
KR101437799B1 (ko) * 2004-12-29 2014-09-11 가부시키가이샤 아루떼꾸 우에노 두피 및 모발 치료용 조성물 및 치료 방법
CN101410097A (zh) 2006-01-24 2009-04-15 株式会社·R-技术上野 软明胶胶囊制剂
EP1994933B1 (en) 2006-03-13 2017-04-26 R-Tech Ueno, Ltd. Aqueous composition
KR20140035363A (ko) 2011-04-07 2014-03-21 수캄포 아게 안정피로 치료 방법
US8592483B2 (en) 2011-08-05 2013-11-26 Sucampo Ag Method for treating schizophrenia
AR092821A1 (es) 2012-04-20 2015-05-06 Sucampo Ag Conjugado de derivado de acido graso-polimero
JP6162646B2 (ja) * 2014-05-27 2017-07-12 信越化学工業株式会社 ３，５−ジメチルドデカン酸の製造方法
US20170020890A1 (en) 2015-06-19 2017-01-26 Sucampo Ag Pharmaceutical composition comprising fatty acid derivative

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3505386A (en) * 1965-12-29 1970-04-07 Upjohn Co Compounds related to prostaglandins
US3984455A (en) * 1973-07-16 1976-10-05 The Upjohn Company Prostaglandin E1 analogs
GB1476661A (en) * 1974-05-13 1977-06-16 American Cyanamid Co Prostaglandins
IL51189A (en) * 1976-02-04 1985-08-30 Upjohn Co Prostaglandin analogs
JPS60208917A (ja) * 1984-02-29 1985-10-21 ジ・アツプジヨン・カンパニー Ａｒｄｓおよび多器官不全治療、予防におけるプロスタグランジンの使用
CA1323364C (en) * 1987-01-28 1993-10-19 Ryuzo Ueno Prostaglandins e and anti ulcer agents containing same
FR2613722B1 (fr) * 1987-04-07 1990-11-23 Bp Chimie Sa Procede de fabrication de granules d'homopolymere ou de copolymere de propylene

Also Published As

Publication number Publication date
EP0289349A1 (en) 1988-11-02
DE3868127D1 (de) 1992-03-12
US5106869A (en) 1992-04-21
CA1324129C (en) 1993-11-09
ATE72235T1 (de) 1992-02-15
KR930006202B1 (ko) 1993-07-08
EP0289349B1 (en) 1992-01-29
KR880012540A (ko) 1988-11-28
GR3003749T3 (es) 1993-03-16
NL300135I1 (nl) 2003-12-01
DE10399038I1 (de) 2004-05-06
JPH0667900B2 (ja) 1994-08-31
NL300135I2 (nl) 2004-05-03
ZA886909B (en) 1989-05-30
DE10399038I2 (de) 2004-09-23
JPH01151552A (ja) 1989-06-14

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Legal Events

Date Code Title Description
SPCF Request for supplementary protection certificate filed

Free format text: PRODUCT NAME: ISOPROPIL UNOPROSTONA (RESCULA), REGISTRY NO/DATE: 65393 20030606, FIRST REGISTRY NO/DATE: FRNL25643 20020917

Spc suppl protection certif: C200300024

Filing date: 20031205