ES2164182T3 - Benzociclopentanoxazolidinonas que contienen heteroatomos con actividad antibacteriana. - Google Patents

Benzociclopentanoxazolidinonas que contienen heteroatomos con actividad antibacteriana.

Info

Publication number
ES2164182T3
ES2164182T3 ES96105539T ES96105539T ES2164182T3 ES 2164182 T3 ES2164182 T3 ES 2164182T3 ES 96105539 T ES96105539 T ES 96105539T ES 96105539 T ES96105539 T ES 96105539T ES 2164182 T3 ES2164182 T3 ES 2164182T3
Authority
ES
Spain
Prior art keywords
heteroatomos
benzociclopentanoxazolidinones
contain
antibacterial activity
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96105539T
Other languages
English (en)
Inventor
Andreas Dr Stolle
Dieter Dr Habich
Stephan Dr Bartel
Bernd Dr Riedl
Martin Dr Ruppelt
Hanno Dr Wild
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19544106A external-priority patent/DE19544106A1/de
Application filed by Bayer AG filed Critical Bayer AG
Application granted granted Critical
Publication of ES2164182T3 publication Critical patent/ES2164182T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
    • C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
    • C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D419/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms
    • C07D419/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D419/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen, oxygen, and sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
    • C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
    • C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
    • C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

LA INVENCION TRATA DE BRNZOCICLOPENTANOXAZOLIDINONAS CONTENIENDO HETEROATOMOS DE FORMULA I, PROCEDIMIENTO PARA SU OBTENCION Y SU UTILIZACION COMO MEDICAMENTOS, ESPECIALMENTE ANTIBACTERIANOS. A ES UN RADICAL DE FORMULA O
ES96105539T 1995-04-21 1996-04-09 Benzociclopentanoxazolidinonas que contienen heteroatomos con actividad antibacteriana. Expired - Lifetime ES2164182T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19514769 1995-04-21
DE19544106A DE19544106A1 (de) 1995-04-21 1995-11-27 Heteroatomhaltige Benzocyclopentanoxazolidinone

Publications (1)

Publication Number Publication Date
ES2164182T3 true ES2164182T3 (es) 2002-02-16

Family

ID=26014539

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96105539T Expired - Lifetime ES2164182T3 (es) 1995-04-21 1996-04-09 Benzociclopentanoxazolidinonas que contienen heteroatomos con actividad antibacteriana.

Country Status (21)

Country Link
US (1) US6069160A (es)
EP (1) EP0738726B1 (es)
JP (1) JP3967401B2 (es)
CN (1) CN1138582A (es)
AT (1) ATE206120T1 (es)
AU (1) AU705071B2 (es)
BG (1) BG100525A (es)
CA (1) CA2174473A1 (es)
CZ (1) CZ114296A3 (es)
EE (1) EE9600043A (es)
ES (1) ES2164182T3 (es)
HR (1) HRP960159A2 (es)
HU (1) HUP9601001A3 (es)
IL (1) IL117954A0 (es)
MA (1) MA23845A1 (es)
MX (1) MX9601399A (es)
NO (1) NO305909B1 (es)
NZ (1) NZ286400A (es)
SG (1) SG52774A1 (es)
SK (1) SK50096A3 (es)
TR (1) TR199600319A2 (es)

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US6617453B1 (en) 1997-10-24 2003-09-09 Clariant Finance (Bvi) Limited Triphendioxazine compounds
DE19747175A1 (de) * 1997-10-24 1999-04-29 Clariant Int Ltd Chlorhaltige Triphendioxazin-Verbindungen
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GB9725244D0 (en) 1997-11-29 1998-01-28 Zeneca Ltd Chemical compounds
US7002020B1 (en) 1998-01-23 2006-02-21 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6239152B1 (en) 1998-01-23 2001-05-29 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
US6562844B2 (en) 1998-01-23 2003-05-13 Pharmacia & Upjohn Company Oxazolidinone combinatorial libraries, compositions and methods of preparation
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DE19905278A1 (de) * 1999-02-09 2000-08-10 Bayer Ag Oxazolidinone und ihre Verwendung als antibakterielle Mittel
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WO2001009107A1 (en) 1999-07-28 2001-02-08 Pharmacia & Upjohn Company Oxazolidinones and their use as antiinfectives
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IL164195A0 (en) * 2002-03-29 2005-12-18 Upjohn Co Parenteral, intravenous, and oral administration of oxazolidinones for treating diabetic foot infections
DE60304360T2 (de) * 2002-08-12 2006-11-16 Pharmacia & Upjohn Co. Llc, Kalamazoo N-aryl-2-oxazolidinone und deren derivate
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US7141570B2 (en) * 2002-11-21 2006-11-28 Pharmacia & Upjohn Company N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
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AR042956A1 (es) 2003-01-31 2005-07-13 Vertex Pharma Inhibidores de girasa y usos de los mismos
US8404852B2 (en) 2003-01-31 2013-03-26 Vertex Pharmaceuticals Incorporated Gyrase inhibitors and uses thereof
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Also Published As

Publication number Publication date
IL117954A0 (en) 1996-08-04
EP0738726B1 (de) 2001-09-26
HU9601001D0 (en) 1996-06-28
US6069160A (en) 2000-05-30
ATE206120T1 (de) 2001-10-15
SG52774A1 (en) 1998-09-28
HUP9601001A3 (en) 1999-03-01
SK50096A3 (en) 1997-05-07
BG100525A (en) 1997-03-31
JPH08301869A (ja) 1996-11-19
EP0738726A1 (de) 1996-10-23
EE9600043A (et) 1996-12-16
NO961559L (no) 1996-10-22
NO305909B1 (no) 1999-08-16
NZ286400A (en) 1998-04-27
AU5073596A (en) 1996-10-31
CZ114296A3 (en) 1997-07-16
AU705071B2 (en) 1999-05-13
MX9601399A (es) 1997-04-30
MA23845A1 (fr) 1996-12-31
JP3967401B2 (ja) 2007-08-29
HUP9601001A2 (hu) 1998-04-28
CA2174473A1 (en) 1996-10-22
CN1138582A (zh) 1996-12-25
HRP960159A2 (en) 1997-08-31
TR199600319A2 (tr) 1996-11-21
NO961559D0 (no) 1996-04-19

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