MX9302461A - Benzo-y piridopiridonas sustituidas por sulfonilbencilo, procedimiento para su obtencion y medicamentos que las contienen. - Google Patents

Benzo-y piridopiridonas sustituidas por sulfonilbencilo, procedimiento para su obtencion y medicamentos que las contienen.

Info

Publication number
MX9302461A
MX9302461A MX9302461A MX9302461A MX9302461A MX 9302461 A MX9302461 A MX 9302461A MX 9302461 A MX9302461 A MX 9302461A MX 9302461 A MX9302461 A MX 9302461A MX 9302461 A MX9302461 A MX 9302461A
Authority
MX
Mexico
Prior art keywords
benzo
substituted
sulfonilbencilo
piridopiridones
medicines
Prior art date
Application number
MX9302461A
Other languages
English (en)
Inventor
Walter Hubsch
Thomas Kramer
Ulrich E Muller
Matthias Muller Gliemann
Martin Beuck
Stanislav Kazda
Jurgen Dressel
Peter Fey
Rudolf H Hanko
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MX9302461A publication Critical patent/MX9302461A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Los benzo- y piridopiridonas sustituídas por sulfonilbencilo se obtienen mediante transformación de las benzo- y piridopiridonas correspondientes con compuestos de sulfonilbencilo.
MX9302461A 1992-05-12 1993-04-27 Benzo-y piridopiridonas sustituidas por sulfonilbencilo, procedimiento para su obtencion y medicamentos que las contienen. MX9302461A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4215587A DE4215587A1 (de) 1992-05-12 1992-05-12 Sulfonylbenzyl-substituierte Benzo- und Pyridopyridone

Publications (1)

Publication Number Publication Date
MX9302461A true MX9302461A (es) 1994-06-30

Family

ID=6458654

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9302461A MX9302461A (es) 1992-05-12 1993-04-27 Benzo-y piridopiridonas sustituidas por sulfonilbencilo, procedimiento para su obtencion y medicamentos que las contienen.

Country Status (21)

Country Link
US (1) US5354749A (es)
EP (1) EP0569795B1 (es)
JP (1) JPH0649031A (es)
KR (1) KR930023362A (es)
CN (1) CN1080923A (es)
AT (1) ATE121086T1 (es)
AU (1) AU3710693A (es)
CA (1) CA2095801A1 (es)
CZ (1) CZ72393A3 (es)
DE (2) DE4215587A1 (es)
DK (1) DK0569795T3 (es)
ES (1) ES2072784T3 (es)
FI (1) FI932105A (es)
GR (1) GR3015836T3 (es)
HU (1) HU9301366D0 (es)
IL (1) IL105646A0 (es)
MX (1) MX9302461A (es)
NO (1) NO931534L (es)
PL (1) PL298890A1 (es)
SK (1) SK46693A3 (es)
ZA (1) ZA933273B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4301900A1 (de) * 1993-01-25 1994-07-28 Bayer Ag 2-Oxochinolin-1-yl-methylphenylessigsäurederivate
TW263498B (es) * 1993-11-10 1995-11-21 Takeda Pharm Industry Co Ltd
EP2332527A3 (en) * 2004-10-20 2011-11-16 Resverlogix Corp. Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases
AU2006275514B2 (en) 2005-07-29 2012-04-05 Resverlogix Corp. Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
PT2118074E (pt) 2007-02-01 2014-03-20 Resverlogix Corp Compostos para a prevenção e tratamento de doenças cardiovasculares
CA2711103C (en) 2008-06-26 2016-08-09 Resverlogix Corp. Methods of preparing quinazolinone derivatives
CN102264701A (zh) 2008-12-23 2011-11-30 霍夫曼-拉罗奇有限公司 作为p2x7调节剂的二氢吡啶酮脲
KR101381074B1 (ko) 2008-12-23 2014-04-11 에프. 호프만-라 로슈 아게 Ｐ2ｘ7 조절제로서의 디히드로피리돈 아미드
US8153808B2 (en) 2008-12-23 2012-04-10 Roche Palo Alto Llc Dihydropyridone amides as P2X7 modulators
EP2382202A1 (en) 2008-12-23 2011-11-02 F. Hoffmann-La Roche AG Dihydropyridone amides as p2x7 modulators
BRPI0923488A2 (pt) 2008-12-23 2019-09-24 Hoffmann La Roche amidas de didropiridona como modulares p2x7
CA2747417C (en) 2009-01-08 2017-01-03 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular disease
CA3146333A1 (en) 2009-03-18 2010-09-23 Resverlogix Corp. Phenyl-quinazolin-4(3h)-one and phenyl-pyrido[2,3-d]pyrimidin-4(3h)-one derivatives and compositions thereof useful as anti-inflammatory agents
LT2421533T (lt) 2009-04-22 2018-12-27 Resverlogix Corp. Nauji priešuždegiminiai agentai
JP5992049B2 (ja) 2011-11-01 2016-09-14 レスバーロジックス コーポレイション 置換されたキナゾリノンのための経口速放性製剤
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
WO2014080291A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Biaryl derivatives as bromodomain inhibitors
AU2013365926B9 (en) 2012-12-21 2019-01-17 Zenith Epigenetics Ltd. Novel heterocyclic compounds as bromodomain inhibitors
WO2016147053A1 (en) 2015-03-13 2016-09-22 Resverlogix Corp. Compositions and therapeutic methods for the treatment of complement-associated diseases
CN110327347B (zh) * 2019-08-16 2021-06-01 陕西科技大学 G-749在制备抗真菌药物中的应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2314985A1 (de) * 1973-03-26 1974-10-17 Hoechst Ag 1-(imidazol-1-yl)-isochinoline und verfahren zu ihrer herstellung
JPS6145820A (ja) * 1984-03-07 1986-03-05 Nippon Piston Ring Co Ltd 粉末成形体の定間隔整列方法及びその整列装置
DE3800785A1 (de) * 1988-01-09 1989-07-20 Hoechst Ag Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
GB8911854D0 (en) * 1989-05-23 1989-07-12 Ici Plc Heterocyclic compounds
IE64514B1 (en) * 1989-05-23 1995-08-09 Zeneca Ltd Azaindenes
EP0955294B1 (en) * 1989-06-14 2003-09-24 Smithkline Beecham Corporation Imidazolyl-alkenoic acid
CA2018443A1 (en) * 1989-06-14 1990-12-14 Joseph A. Finkelstein Imidazolyl-alkenoic acids
US5164407A (en) * 1989-07-03 1992-11-17 Merck & Co., Inc. Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists
EP0485410A1 (en) * 1989-07-06 1992-05-20 The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern A detector for monitoring low molecular weight compounds
YU155290A (sh) * 1989-08-11 1993-05-28 Imperial Chemical Industries Plc. Dusikove spojine
CA2027937A1 (en) * 1989-10-25 1991-04-26 Richard M. Keenan Substituted 5-¬ (tetrazolyl)alkenyl|imidazoles
JP2860676B2 (ja) * 1989-12-07 1999-02-24 川研ファインケミカル株式会社 １―イソキノリン類の製造方法
GB9010394D0 (en) * 1990-05-09 1990-06-27 Ici Plc Heterocyclic compounds
IE912956A1 (en) * 1990-09-10 1992-03-11 Abbott Lab Angiotensin ii receptor antagonists
GB9025123D0 (en) * 1990-11-19 1991-01-02 Ici Plc Nitrogen compounds
US5162325A (en) * 1991-05-07 1992-11-10 Merck & Co., Inc. Angiotensin ii antagonists incorporating a substituted benzyl element
US5162340A (en) * 1991-05-10 1992-11-10 Merck & Co., Inc. Substituted 1-(2h)-isoquinolinones bearing acidic functional groups as angiotensin ii antagonists
US5256667A (en) * 1991-09-25 1993-10-26 Merck & Co., Inc. Quinazolinones and pyridopyrimidinones
DE4206045A1 (de) * 1992-02-27 1993-09-02 Bayer Ag Sulfonylbenzyl substituierte pyridone

Also Published As

Publication number Publication date
ATE121086T1 (de) 1995-04-15
FI932105A0 (fi) 1993-05-10
CA2095801A1 (en) 1993-11-13
DK0569795T3 (da) 1995-08-28
NO931534D0 (no) 1993-04-27
PL298890A1 (en) 1994-01-10
US5354749A (en) 1994-10-11
HU9301366D0 (en) 1993-09-28
CN1080923A (zh) 1994-01-19
FI932105A (fi) 1993-11-13
ZA933273B (en) 1993-11-29
IL105646A0 (en) 1993-09-22
GR3015836T3 (en) 1995-07-31
CZ72393A3 (en) 1993-12-15
NO931534L (no) 1993-11-15
EP0569795B1 (de) 1995-04-12
KR930023362A (ko) 1993-12-18
DE59300135D1 (de) 1995-05-18
ES2072784T3 (es) 1995-07-16
JPH0649031A (ja) 1994-02-22
SK46693A3 (en) 1994-02-02
DE4215587A1 (de) 1993-11-18
AU3710693A (en) 1993-11-18
EP0569795A1 (de) 1993-11-18

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