MX9302487A - Piridonas sustituidas por bifenilmetilo, procedimiento para su obtencion y medicamentos que las contienen. - Google Patents

Piridonas sustituidas por bifenilmetilo, procedimiento para su obtencion y medicamentos que las contienen.

Info

Publication number
MX9302487A
MX9302487A MX9302487A MX9302487A MX9302487A MX 9302487 A MX9302487 A MX 9302487A MX 9302487 A MX9302487 A MX 9302487A MX 9302487 A MX9302487 A MX 9302487A MX 9302487 A MX9302487 A MX 9302487A
Authority
MX
Mexico
Prior art keywords
substituted
medicines
piridonas
biphenylmethyll
procedure
Prior art date
Application number
MX9302487A
Other languages
English (en)
Inventor
Jurgen Dressel
Peter Fey
Rudolf H Hanko
Walter Hubsch
Thomas Kramer
Ulrich E Muller Stefa Wohlfeil
Matthias Muller-Gliemann
Martin Beuck Andreas Knorr
Kazda Johannes-Peter Stanislav
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of MX9302487A publication Critical patent/MX9302487A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D421/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms
    • C07D421/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms containing two hetero rings
    • C07D421/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having selenium, tellurium, or halogen atoms as ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)

Abstract

Las piridonas sustituídas por bifenilmetilo se obtienen mediante transformación de piridonas con los compuestos de bifenilmetilo correspondientes. Las piridonas sustituídas por bifenilmetilo pueden emplearse como sustancias activas en medicamentos, especialmente para el tratamiento de hipertensión arterial y aterosclerosis.
MX9302487A 1992-05-12 1993-04-28 Piridonas sustituidas por bifenilmetilo, procedimiento para su obtencion y medicamentos que las contienen. MX9302487A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4215588A DE4215588A1 (de) 1992-05-12 1992-05-12 Biphenylmethyl-substituierte Pyridone

Publications (1)

Publication Number Publication Date
MX9302487A true MX9302487A (es) 1993-11-01

Family

ID=6458655

Family Applications (1)

Application Number Title Priority Date Filing Date
MX9302487A MX9302487A (es) 1992-05-12 1993-04-28 Piridonas sustituidas por bifenilmetilo, procedimiento para su obtencion y medicamentos que las contienen.

Country Status (16)

Country Link
US (1) US5407942A (es)
EP (1) EP0569794A1 (es)
JP (1) JPH0656783A (es)
KR (1) KR930023364A (es)
CN (1) CN1082029A (es)
AU (1) AU3710993A (es)
CA (1) CA2095802A1 (es)
CZ (1) CZ72193A3 (es)
DE (1) DE4215588A1 (es)
FI (1) FI932106A (es)
HU (1) HU9301365D0 (es)
IL (1) IL105647A0 (es)
MX (1) MX9302487A (es)
NO (1) NO931535L (es)
SK (1) SK46793A3 (es)
ZA (1) ZA933274B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW263498B (es) * 1993-11-10 1995-11-21 Takeda Pharm Industry Co Ltd
EP1838296B1 (en) 2004-10-20 2012-08-08 Resverlogix Corp. Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases
EP2314295B1 (en) 2005-07-29 2015-01-28 Resverlogix, Inc Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
US8053440B2 (en) 2007-02-01 2011-11-08 Resverlogix Corporation Compounds for the prevention and treatment of cardiovascular diseases
PT2346837E (pt) 2008-06-26 2015-04-02 Resverlogix Corp Métodos de preparação de derivados de quinazolinona
ES2542835T3 (es) 2009-01-08 2015-08-12 Resverlogix Corporation Compuestos para la prevención y el tratamiento de enfermedades cardiovasculares
BRPI1009315B8 (pt) 2009-03-18 2021-05-25 Resverlogix Corp composto anti-flamatórios e suas composições farmacêuticas
TR201818390T4 (tr) 2009-04-22 2019-01-21 Resverlogix Corp Yeni̇ anti̇-i̇nflamatuvar ajanlar
PL2773354T3 (pl) 2011-11-01 2019-12-31 Resverlogix Corp. Doustna formulacja o natychmiastowym uwalnianiu dla podstawowych chinazolinów
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
WO2014080291A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Biaryl derivatives as bromodomain inhibitors
CA2895905A1 (en) 2012-12-21 2014-06-26 Zenith Epigenetics Corp. Novel heterocyclic compounds as bromodomain inhibitors
US10111885B2 (en) 2015-03-13 2018-10-30 Resverlogix Corp. Compositions and therapeutic methods for the treatment of complement-associated diseases
CN111662228B (zh) * 2019-03-07 2023-07-28 中国医学科学院药物研究所 吡啶酮酰联芳基胺类化合物及其用途

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3406329A1 (de) * 1984-02-22 1985-08-22 Merck Patent Gmbh, 6100 Darmstadt Pyridone
DE3800785A1 (de) * 1988-01-09 1989-07-20 Hoechst Ag Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
IE64514B1 (en) * 1989-05-23 1995-08-09 Zeneca Ltd Azaindenes
GB8911854D0 (en) * 1989-05-23 1989-07-12 Ici Plc Heterocyclic compounds
ATE250587T1 (de) * 1989-06-14 2003-10-15 Smithkline Beecham Corp Imidazoalkensäure
CA2018443A1 (en) * 1989-06-14 1990-12-14 Joseph A. Finkelstein Imidazolyl-alkenoic acids
US5164407A (en) * 1989-07-03 1992-11-17 Merck & Co., Inc. Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists
WO1991001001A1 (en) * 1989-07-06 1991-01-24 The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland A detector for monitoring low molecular weight compounds
AU640417B2 (en) * 1989-10-25 1993-08-26 Smithkline Beecham Corporation Substituted 5-((tetrazolyl)alkenyl)imidazoles
AU653734B2 (en) * 1990-06-19 1994-10-13 Meiji Seika Kabushiki Kaisha Substituted 4-biphenylmethoxypyridine derivatives
IL100917A0 (en) * 1991-02-16 1992-11-15 Fisons Plc Pyridinone and pyrimidinone derivatives,their preparation and pharmaceutical compositions containing them
DE4129340A1 (de) * 1991-09-04 1993-03-11 Merck Patent Gmbh 1,2-dihydro-2-oxopyridine

Also Published As

Publication number Publication date
DE4215588A1 (de) 1993-11-18
NO931535D0 (no) 1993-04-27
AU3710993A (en) 1993-11-18
ZA933274B (en) 1993-11-29
SK46793A3 (en) 1994-02-02
CA2095802A1 (en) 1993-11-13
NO931535L (no) 1993-11-15
US5407942A (en) 1995-04-18
EP0569794A1 (de) 1993-11-18
KR930023364A (ko) 1993-12-18
HU9301365D0 (en) 1993-09-28
JPH0656783A (ja) 1994-03-01
IL105647A0 (en) 1993-09-22
CZ72193A3 (en) 1994-01-19
FI932106A (fi) 1993-11-13
CN1082029A (zh) 1994-02-16
FI932106A0 (fi) 1993-05-10

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