ES2083597T3 - Preparacion farmaceutica para el tratamiento del tiempo de coagulacion prolongado. - Google Patents

Preparacion farmaceutica para el tratamiento del tiempo de coagulacion prolongado.

Info

Publication number
ES2083597T3
ES2083597T3 ES91919614T ES91919614T ES2083597T3 ES 2083597 T3 ES2083597 T3 ES 2083597T3 ES 91919614 T ES91919614 T ES 91919614T ES 91919614 T ES91919614 T ES 91919614T ES 2083597 T3 ES2083597 T3 ES 2083597T3
Authority
ES
Spain
Prior art keywords
treatment
pharmaceutical preparation
coagulation time
prolonged coagulation
prolonged
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91919614T
Other languages
English (en)
Inventor
Ole Nordfang
Ulla Hedner
Niels Peter Moller
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novo Nordisk AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Application granted granted Critical
Publication of ES2083597T3 publication Critical patent/ES2083597T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/38—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against protease inhibitors of peptide structure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Cephalosporin Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

UNA PREPARACION FARMACEUTICA QUE, COMO COMPONENTE ACTIVO CONTIENE UN AGENTE QUE BLOQUEARA LA ACTIVIDAD EPI (INHIBIDOR DE EPI), ES UTIL EN EL TRATAMIENTO DE PACIENTES CON TIEMPO DE COAGULACION PROLONGADO.
ES91919614T 1990-10-31 1991-10-18 Preparacion farmaceutica para el tratamiento del tiempo de coagulacion prolongado. Expired - Lifetime ES2083597T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK261490A DK261490D0 (da) 1990-10-31 1990-10-31 New pharmaceutical compound

Publications (1)

Publication Number Publication Date
ES2083597T3 true ES2083597T3 (es) 1996-04-16

Family

ID=8113744

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91919614T Expired - Lifetime ES2083597T3 (es) 1990-10-31 1991-10-18 Preparacion farmaceutica para el tratamiento del tiempo de coagulacion prolongado.

Country Status (15)

Country Link
EP (1) EP0558529B1 (es)
JP (1) JPH06502171A (es)
AT (1) ATE132757T1 (es)
AU (1) AU657926B2 (es)
CA (1) CA2095356A1 (es)
CZ (1) CZ282497B6 (es)
DE (1) DE69116380T2 (es)
DK (2) DK261490D0 (es)
ES (1) ES2083597T3 (es)
GR (1) GR3019514T3 (es)
HU (1) HUT64236A (es)
RU (1) RU2127600C1 (es)
SK (1) SK282516B6 (es)
UA (1) UA35567C2 (es)
WO (1) WO1992007584A1 (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6063764A (en) * 1992-06-01 2000-05-16 Washington University & Chiron Corp. Method for using lipoprotein associated coagulation inhibitor to treat sepsis
US20030171292A1 (en) 1992-06-01 2003-09-11 Creasey Abla A. Method for using lipoprotein associated coagulation inhibitor to treat sepsis
GB2268909B (en) * 1992-07-21 1995-10-25 Profy International Corp Unitary loose sheet binder
RU2195676C2 (ru) * 1999-08-26 2002-12-27 Уральская государственная медицинская академия Способ комплексной оценки прогноза эффективности лечения диффузных заболеваний соединительной ткани низкомолекулярными антикоагулянтами
US7015194B2 (en) 2000-05-10 2006-03-21 Novo Nordisk A/S Pharmaceutical composition comprising factor VIIa and anti-TFPI
EP1593389A1 (en) * 2000-05-10 2005-11-09 Novo Nordisk Health Care AG Pharmaceutical composition comprising a factor VIIa and a factor XIII
CA2463655A1 (en) 2001-10-15 2003-04-24 Chiron Corporation Treatment of severe pneumonia by administration of tissue factor pathway inhibitor (tfpi)
EP1919499A2 (en) * 2005-07-29 2008-05-14 Universiteit van Maastricht Regulation of tissue factor activity by protein s and tissue factor pathway inhibitor
MX2010013565A (es) 2008-06-30 2011-01-14 Novo Nordisk As Anticuerpos de interleucina-20 anti-humanos.
UA112050C2 (uk) * 2008-08-04 2016-07-25 БАЄР ХЕЛСКЕР ЛЛСі Терапевтична композиція, що містить моноклональне антитіло проти інгібітора шляху тканинного фактора (tfpi)
US8962563B2 (en) 2009-12-21 2015-02-24 Baxter International, Inc. TFPI inhibitors and methods of use
LT2379096T (lt) 2008-12-19 2019-12-27 Baxalta GmbH Tfpi inhibitoriai ir vartojimo būdai
EP2379600B2 (en) 2008-12-22 2020-10-14 Novo Nordisk A/S Antibodies against tissue factor pathway inhibitor
US8454956B2 (en) 2009-08-31 2013-06-04 National Cheng Kung University Methods for treating rheumatoid arthritis and osteoporosis with anti-IL-20 antibodies
CN107496917B (zh) * 2010-02-26 2021-06-11 诺沃—诺迪斯克有限公司 包含稳定抗体的组合物
SG183443A1 (en) 2010-03-01 2012-09-27 Bayer Healthcare Llc Optimized monoclonal antibodies against tissue factor pathway inhibitor (tfpi)
EP2547355B1 (en) 2010-03-19 2017-01-11 Baxalta GmbH Tfpi inhibitors and methods of use
MX2012013586A (es) 2010-05-28 2013-01-24 Novo Nordisk As Composiciones multi-dosis estables que comprenden un anticuerpo y un conservante.
WO2012001087A1 (en) * 2010-06-30 2012-01-05 Novo Nordisk A/S Antibodies that are capable of specifically binding tissue factor pathway inhibitor
US9228022B2 (en) 2010-06-30 2016-01-05 Novo Nordisk A/S Antibodies that are capable of specifically binding tissue factor pathway inhibitor
US9221904B2 (en) 2012-07-19 2015-12-29 National Cheng Kung University Treatment of osteoarthritis using IL-20 antagonists
US8852588B2 (en) 2012-08-07 2014-10-07 National Cheng Kung University Treating allergic airway disorders using anti-IL-20 receptor antibodies
US8603470B1 (en) 2012-08-07 2013-12-10 National Cheng Kung University Use of IL-20 antagonists for treating liver diseases

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4359463A (en) * 1980-11-26 1982-11-16 Rock Gail A Stabilization of Factor VIII activity in whole blood or blood plasma
DE3237512A1 (de) * 1982-10-09 1984-04-12 Behringwerke Ag, 3550 Marburg Verfahren zur pasteurisierung von antihaemophilem kryopraezipitat (ahk) und danach hergestelltes antihaemophiles kryopraezipitat
IL87172A (en) * 1987-07-23 1994-12-29 Univ Washington Method of isolating highly purified tissue factor inhibitor
IL87171A (en) * 1987-11-23 1995-08-31 Monsanto Co cDNA of human tissue factor inhibitor
JP2846385B2 (ja) 1988-03-17 1999-01-13 ノボ・ノルデイスク エー／エス ヘパリン結合タンパク、それらをコードするｄｎａ、それらの製造方法およびそれらを含有する治療用調製品
DK148890D0 (da) * 1990-06-19 1990-06-19 Novo Nordisk As Farmaceutisk praeparat

Also Published As

Publication number Publication date
EP0558529B1 (en) 1996-01-10
CZ282497B6 (cs) 1997-07-16
CA2095356A1 (en) 1992-05-01
HU9301253D0 (en) 1993-07-28
CZ78693A3 (en) 1993-12-15
DE69116380D1 (de) 1996-02-22
EP0558529A1 (en) 1993-09-08
AU657926B2 (en) 1995-03-30
GR3019514T3 (en) 1996-07-31
AU8871191A (en) 1992-05-26
UA35567C2 (uk) 2001-04-16
SK42893A3 (en) 1993-09-08
HUT64236A (en) 1993-12-28
DK0558529T3 (da) 1996-06-03
DE69116380T2 (de) 1996-07-11
WO1992007584A1 (en) 1992-05-14
ATE132757T1 (de) 1996-01-15
RU2127600C1 (ru) 1999-03-20
SK282516B6 (sk) 2002-10-08
JPH06502171A (ja) 1994-03-10
DK261490D0 (da) 1990-10-31

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