ES2161697T3 - Peptidos agonistas de amilina y usos de los mismos. - Google Patents

Peptidos agonistas de amilina y usos de los mismos.

Info

Publication number
ES2161697T3
ES2161697T3 ES92924442T ES92924442T ES2161697T3 ES 2161697 T3 ES2161697 T3 ES 2161697T3 ES 92924442 T ES92924442 T ES 92924442T ES 92924442 T ES92924442 T ES 92924442T ES 2161697 T3 ES2161697 T3 ES 2161697T3
Authority
ES
Spain
Prior art keywords
amilina
agonistas
peptides
same
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92924442T
Other languages
English (en)
Inventor
Laura S L Gaeta
Howard Jones
Elisabeth Albrecht
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amylin Pharmaceuticals LLC
Original Assignee
Amylin Pharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amylin Pharmaceuticals LLC filed Critical Amylin Pharmaceuticals LLC
Application granted granted Critical
Publication of ES2161697T3 publication Critical patent/ES2161697T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

SE PREVEN DERIVADOS AGONISTAS DE AMILINA, LAS COMPOSICIONES FARMACEUTICAS DESCRITAS, Y METODOS DE TRATAMIENTO DE LA DIABETES Y OTROS ESTADO QUE REQUIEREN INSULINA, ASI COMO METODOS PARA EL TRATAMIENTO DE LA HIPOGLUCEMIA.
ES92924442T 1991-11-19 1992-11-19 Peptidos agonistas de amilina y usos de los mismos. Expired - Lifetime ES2161697T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US79426691A 1991-11-19 1991-11-19

Publications (1)

Publication Number Publication Date
ES2161697T3 true ES2161697T3 (es) 2001-12-16

Family

ID=25162163

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92924442T Expired - Lifetime ES2161697T3 (es) 1991-11-19 1992-11-19 Peptidos agonistas de amilina y usos de los mismos.

Country Status (17)

Country Link
EP (2) EP1162207A1 (es)
JP (4) JP2902115B2 (es)
AT (1) ATE205854T1 (es)
AU (1) AU714439B2 (es)
CA (1) CA2100745C (es)
CZ (1) CZ288029B6 (es)
DE (1) DE69232064T2 (es)
DK (1) DK0567626T3 (es)
ES (1) ES2161697T3 (es)
FI (1) FI118601B (es)
GR (1) GR3036794T3 (es)
HK (1) HK1041891A1 (es)
MD (1) MD960317A (es)
NO (2) NO324405B1 (es)
RU (1) RU2130463C1 (es)
SK (1) SK88793A3 (es)
WO (1) WO1993010146A1 (es)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU222249B1 (hu) 1991-03-08 2003-05-28 Amylin Pharmaceuticals Inc. Eljárás amilin agonista peptidszármazékok és ezeket tartalmazó gyógyszerkészítmények előállítására
US5625032A (en) * 1993-07-21 1997-04-29 Amylin Pharmaceuticals, Inc. Selective amylin antagonist peptides and uses therefor
AU7685894A (en) * 1993-09-07 1995-03-27 Amylin Pharmaceuticals, Inc. Methods for regulating gastrointestinal motility
US5739106A (en) * 1995-06-07 1998-04-14 Rink; Timothy J. Appetite regulating compositions
US6143718A (en) * 1995-06-07 2000-11-07 Amylin Pharmaceuticals, Inc. Treatment of Type II diabetes mellutis with amylin agonists
US7312196B2 (en) 1997-01-08 2007-12-25 Amylin Pharmaceuticals, Inc. Formulations for amylin agonist peptides
US6410511B2 (en) 1997-01-08 2002-06-25 Amylin Pharmaceuticals, Inc. Formulations for amylin agonist peptides
US7101853B2 (en) * 1997-05-06 2006-09-05 Amylin Pharmaceuticals, Inc. Method for treating or preventing gastritis using amylin or amylin agonists
US7910548B2 (en) 1997-06-06 2011-03-22 Amylin Pharmaceuticals, Inc. Methods for treating obesity
JP4353544B2 (ja) * 1998-01-09 2009-10-28 アミリン・ファーマシューティカルズ，インコーポレイテッド アミリン作動薬ペプチド用製剤
NZ514414A (en) * 1999-03-04 2004-02-27 Praecis Pharm Inc Modulators of beta-amyloid peptide aggregation comprising D-amino acids
GB0002952D0 (en) * 2000-02-09 2000-03-29 Pharma Mar Sa Process for producing kahalalide F compounds
RU2228174C2 (ru) * 2000-04-10 2004-05-10 Помыткин Игорь Анатольевич Янтарнокислый бис(2-гидрокси-n,n,n-триметилэтанаминий) для лечения инсулиновой резистентности, сахарного диабета, гиперлипидемии и дислипидемии
GB0128583D0 (en) 2001-11-28 2002-01-23 Rsr Ltd Detection of autoantibodies indicative of diabetes
AU2003278929A1 (en) 2002-10-18 2004-05-13 Amylin Pharmaceuticals, Inc. Treatment of pancreatitis with amylin
GB0304367D0 (en) * 2003-02-26 2003-04-02 Pharma Mar Sau Methods for treating psoriasis
AU2004222110A1 (en) * 2003-03-18 2004-09-30 Laboratoires Serono Sa Amylin aggregation inhibitors and use thereof.
KR20070083815A (ko) * 2004-10-26 2007-08-24 론자 아게 고체상 합성에서 ｓ-알킬-술페닐 보호기
ES2325773T5 (es) 2004-11-01 2014-02-24 Amylin Pharmaceuticals, Llc. Tratamiento de la obesidad y de los trastornos relacionados
US8394765B2 (en) 2004-11-01 2013-03-12 Amylin Pharmaceuticals Llc Methods of treating obesity with two different anti-obesity agents
WO2006105527A2 (en) 2005-03-31 2006-10-05 Amylin Pharmaceuticals, Inc. Amylin and amylin agonists for treating psychiatric diseases and disorders
US8168592B2 (en) 2005-10-21 2012-05-01 Amgen Inc. CGRP peptide antagonists and conjugates
CA2662084A1 (en) 2006-09-07 2008-03-13 Nycomed Gmbh Combination treatment for diabetes mellitus
ES2389747T3 (es) 2007-02-05 2012-10-31 Amylin Pharmaceuticals, Inc. Péptidos FN-38 para su uso en el tratamiento de desórdenes psicóticos y de ansiedad
JP2009149684A (ja) * 2009-03-11 2009-07-09 Amylin Pharmaceut Inc アミリン作動薬ペプチド用製剤
EP2762150A1 (en) 2009-03-12 2014-08-06 Nordic Bioscience A/S Treatment of Diabetes and Metabolic Syndrome
AR097701A1 (es) * 2013-09-19 2016-04-13 Zealand Pharma As Análogos de amilina
WO2015068156A1 (en) 2013-11-05 2015-05-14 Ben-Gurion University Of The Negev Research And Development Authority Compounds for the treatment of diabetes and disease complications arising from same
WO2015168488A2 (en) * 2014-05-02 2015-11-05 The Research Foundation For The State University Of New York Islet amyloid polypeptides with improved solubility
CN107567459B (zh) * 2015-03-18 2021-09-24 西兰制药公司 胰淀素类似物
TWI784968B (zh) 2016-09-09 2022-12-01 丹麥商西蘭製藥公司 澱粉素類似物
WO2018144671A1 (en) 2017-02-01 2018-08-09 The Research Foundation For The State University Of New York Mutant islet amyloid polypeptides with improved solubility and methods for using the same
KR102130354B1 (ko) * 2019-08-14 2020-07-06 엘아이지넥스원 주식회사 코어 제거용 이형장치
ES3010934T3 (en) 2022-05-30 2025-04-04 Zealand Pharma As Liquid formulations of amylin analogues
IL319599A (en) 2022-09-19 2025-05-01 Zealand Pharma As Combination therapy
WO2024261076A1 (en) 2023-06-21 2024-12-26 Zealand Pharma A/S Weight loss
TW202515598A (zh) 2023-06-21 2025-04-16 丹麥商西蘭製藥公司 具有增進性能之類似物
TW202517291A (zh) 2023-06-30 2025-05-01 丹麥商西蘭製藥公司 組合療法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5120712A (en) * 1986-05-05 1992-06-09 The General Hospital Corporation Insulinotropic hormone
GB8720115D0 (en) * 1987-08-26 1987-09-30 Cooper G J S Treatment of diabetes mellitus
EP0348490B1 (en) * 1988-01-11 1995-09-27 Amylin Pharmaceuticals, Inc. Treatment of type 2 diabetes mellitus
CA2020786A1 (en) * 1989-07-10 1991-01-11 Amylin Pharmaceuticals, Inc. Treatment of obesity and essential hypertension and related disorders
US5234906A (en) * 1991-01-10 1993-08-10 Amylin Pharmaceuticals, Inc. Hyperglycemic compositions
WO1992015317A1 (en) * 1991-03-08 1992-09-17 Amylin Pharmaceuticals, Inc. Synthetic preparation of amylin and amylin analogues

Also Published As

Publication number Publication date
FI118601B (fi) 2008-01-15
CZ288029B6 (cs) 2001-04-11
SK88793A3 (en) 1994-12-07
CZ168993A3 (en) 1994-04-13
JP2902115B2 (ja) 1999-06-07
EP1162207A1 (en) 2001-12-12
GR3036794T3 (en) 2002-01-31
AU1245697A (en) 1997-03-27
AU3075392A (en) 1993-06-15
HK1041891A1 (en) 2002-07-26
JPH06504794A (ja) 1994-06-02
JP4018116B2 (ja) 2007-12-05
DE69232064T2 (de) 2002-03-28
WO1993010146A1 (en) 1993-05-27
AU714439B2 (en) 2000-01-06
NO932603D0 (no) 1993-07-19
NO932603L (no) 1993-09-17
EP0567626A1 (en) 1993-11-03
EP0567626B1 (en) 2001-09-19
FI933252A0 (fi) 1993-07-16
CA2100745A1 (en) 1993-05-20
ATE205854T1 (de) 2001-10-15
MD960317A (ro) 1998-05-31
JP2003238594A (ja) 2003-08-27
AU673147B2 (en) 1996-10-31
FI933252L (fi) 1993-08-23
DE69232064D1 (de) 2001-10-25
DK0567626T3 (da) 2001-12-17
JPH11152299A (ja) 1999-06-08
JP2006213716A (ja) 2006-08-17
NO20073265L (no) 1993-09-17
RU2130463C1 (ru) 1999-05-20
CA2100745C (en) 2007-07-31
NO324405B1 (no) 2007-10-08

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