ZA933273B - Sulfonylbenzyl-substituted benzo- and pyridopyridones - Google Patents

Sulfonylbenzyl-substituted benzo- and pyridopyridones

Info

Publication number
ZA933273B
ZA933273B ZA933273A ZA933273A ZA933273B ZA 933273 B ZA933273 B ZA 933273B ZA 933273 A ZA933273 A ZA 933273A ZA 933273 A ZA933273 A ZA 933273A ZA 933273 B ZA933273 B ZA 933273B
Authority
ZA
South Africa
Prior art keywords
pyridopyridones
substituted benzo
sulfonylbenzyl
sulphonylbenzyl
benzo
Prior art date
Application number
ZA933273A
Other languages
English (en)
Inventor
Juergen Dr Dressel
Peter Dr Fey
Rudolf H Dr Hanko
Walter Dr Huebsch
Thomas Dr Kraemer
Ulrich E Dr Mueller
Matthias Dr Mueller-Gliemann
Martin Dr Beuck
Stanislav Prof Dr Kazda
Stefan Dr Wohifeil
Andreas Dr Knorr
Johannes-Peter Dr Stasch
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA933273B publication Critical patent/ZA933273B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA933273A 1992-05-12 1993-05-11 Sulfonylbenzyl-substituted benzo- and pyridopyridones ZA933273B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4215587A DE4215587A1 (de) 1992-05-12 1992-05-12 Sulfonylbenzyl-substituierte Benzo- und Pyridopyridone

Publications (1)

Publication Number Publication Date
ZA933273B true ZA933273B (en) 1993-11-29

Family

ID=6458654

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA933273A ZA933273B (en) 1992-05-12 1993-05-11 Sulfonylbenzyl-substituted benzo- and pyridopyridones

Country Status (21)

Country Link
US (1) US5354749A (xx)
EP (1) EP0569795B1 (xx)
JP (1) JPH0649031A (xx)
KR (1) KR930023362A (xx)
CN (1) CN1080923A (xx)
AT (1) ATE121086T1 (xx)
AU (1) AU3710693A (xx)
CA (1) CA2095801A1 (xx)
CZ (1) CZ72393A3 (xx)
DE (2) DE4215587A1 (xx)
DK (1) DK0569795T3 (xx)
ES (1) ES2072784T3 (xx)
FI (1) FI932105A (xx)
GR (1) GR3015836T3 (xx)
HU (1) HU9301366D0 (xx)
IL (1) IL105646A0 (xx)
MX (1) MX9302461A (xx)
NO (1) NO931534L (xx)
PL (1) PL298890A1 (xx)
SK (1) SK46693A3 (xx)
ZA (1) ZA933273B (xx)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110327347A (zh) * 2019-08-16 2019-10-15 陕西科技大学 G-749在制备抗真菌药物中的应用

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4301900A1 (de) * 1993-01-25 1994-07-28 Bayer Ag 2-Oxochinolin-1-yl-methylphenylessigsäurederivate
TW263498B (xx) * 1993-11-10 1995-11-21 Takeda Pharm Industry Co Ltd
WO2006045010A2 (en) * 2004-10-20 2006-04-27 Resverlogix Corp. Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases
AU2006275514B2 (en) 2005-07-29 2012-04-05 Resverlogix Corp. Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
DK2118074T3 (en) * 2007-02-01 2014-03-10 Resverlogix Corp Compounds for the prevention and treatment of cardiovascular diseases
DK2346837T3 (en) 2008-06-26 2015-04-20 Resverlogix Corp Methods for preparing quinazolinone derivatives
US8153808B2 (en) 2008-12-23 2012-04-10 Roche Palo Alto Llc Dihydropyridone amides as P2X7 modulators
KR101370130B1 (ko) 2008-12-23 2014-03-05 에프. 호프만-라 로슈 아게 Ｐ2ｘ7 조절제로서의 디히드로피리돈 아미드
JP2012513435A (ja) 2008-12-23 2012-06-14 エフ．ホフマン−ラ ロシュ アーゲー Ｐ２ｘ７調節薬としてのジヒドロピリドンアミド
EP2385939A1 (en) 2008-12-23 2011-11-16 F. Hoffmann-La Roche AG Dihydropyridone amides as p2x7 modulators
MX2011006843A (es) 2008-12-23 2011-08-04 Hoffmann La Roche Dihidropiridona-amidas como moduladores de p2x7.
ES2463097T3 (es) 2009-01-08 2014-05-27 Resverlogix Corp. Compuestos para la prevención y el tratamiento de enfermedades cardiovasculares
CA2754509C (en) 2009-03-18 2018-03-06 Resverlogix Corp. Novel anti-inflammatory agents
PT2421533T (pt) 2009-04-22 2019-01-21 Resverlogix Corp Novos agentes anti-inflamatórios
HUE044986T2 (hu) 2011-11-01 2019-11-28 Resverlogix Corp Orális, azonnali felszabadulású készítmények szubsztituált kinazolinonokhoz
US9765039B2 (en) 2012-11-21 2017-09-19 Zenith Epigenetics Ltd. Biaryl derivatives as bromodomain inhibitors
WO2014080290A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Cyclic amines as bromodomain inhibitors
JP2016507496A (ja) 2012-12-21 2016-03-10 ゼニス・エピジェネティクス・コーポレイションＺｅｎｉｔｈ Ｅｐｉｇｅｎｅｔｉｃｓ Ｃｏｒｐ． ブロモドメイン阻害剤としての新規複素環式化合物
JO3789B1 (ar) 2015-03-13 2021-01-31 Resverlogix Corp التراكيب والوسائل العلاجية المعتمدة لمعالجة الامراض المتعلقة بالمتممة

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2314985A1 (de) * 1973-03-26 1974-10-17 Hoechst Ag 1-(imidazol-1-yl)-isochinoline und verfahren zu ihrer herstellung
JPS6145820A (ja) * 1984-03-07 1986-03-05 Nippon Piston Ring Co Ltd 粉末成形体の定間隔整列方法及びその整列装置
DE3800785A1 (de) * 1988-01-09 1989-07-20 Hoechst Ag Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
GB8911854D0 (en) * 1989-05-23 1989-07-12 Ici Plc Heterocyclic compounds
IE64514B1 (en) * 1989-05-23 1995-08-09 Zeneca Ltd Azaindenes
EP0403158A3 (en) * 1989-06-14 1991-12-18 Smithkline Beecham Corporation Imidazolyl-alkenoic acids
DE69034103T2 (de) * 1989-06-14 2004-07-15 Smithkline Beecham Corp. Imidazoalkensäure
US5164407A (en) * 1989-07-03 1992-11-17 Merck & Co., Inc. Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists
WO1991001001A1 (en) * 1989-07-06 1991-01-24 The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland A detector for monitoring low molecular weight compounds
FI903966A0 (fi) * 1989-08-11 1990-08-10 Ici Plc Kvaevefoereningar.
AU640417B2 (en) * 1989-10-25 1993-08-26 Smithkline Beecham Corporation Substituted 5-((tetrazolyl)alkenyl)imidazoles
JP2860676B2 (ja) * 1989-12-07 1999-02-24 川研ファインケミカル株式会社 １―イソキノリン類の製造方法
GB9010394D0 (en) * 1990-05-09 1990-06-27 Ici Plc Heterocyclic compounds
IE912956A1 (en) * 1990-09-10 1992-03-11 Abbott Lab Angiotensin ii receptor antagonists
GB9025123D0 (en) * 1990-11-19 1991-01-02 Ici Plc Nitrogen compounds
US5162325A (en) * 1991-05-07 1992-11-10 Merck & Co., Inc. Angiotensin ii antagonists incorporating a substituted benzyl element
US5162340A (en) * 1991-05-10 1992-11-10 Merck & Co., Inc. Substituted 1-(2h)-isoquinolinones bearing acidic functional groups as angiotensin ii antagonists
US5256667A (en) * 1991-09-25 1993-10-26 Merck & Co., Inc. Quinazolinones and pyridopyrimidinones
DE4206045A1 (de) * 1992-02-27 1993-09-02 Bayer Ag Sulfonylbenzyl substituierte pyridone

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110327347A (zh) * 2019-08-16 2019-10-15 陕西科技大学 G-749在制备抗真菌药物中的应用

Also Published As

Publication number Publication date
NO931534L (no) 1993-11-15
US5354749A (en) 1994-10-11
ATE121086T1 (de) 1995-04-15
CA2095801A1 (en) 1993-11-13
CN1080923A (zh) 1994-01-19
HU9301366D0 (en) 1993-09-28
EP0569795B1 (de) 1995-04-12
KR930023362A (ko) 1993-12-18
DE59300135D1 (de) 1995-05-18
CZ72393A3 (en) 1993-12-15
DE4215587A1 (de) 1993-11-18
FI932105A (fi) 1993-11-13
PL298890A1 (en) 1994-01-10
MX9302461A (es) 1994-06-30
FI932105A0 (fi) 1993-05-10
GR3015836T3 (en) 1995-07-31
EP0569795A1 (de) 1993-11-18
IL105646A0 (en) 1993-09-22
ES2072784T3 (es) 1995-07-16
JPH0649031A (ja) 1994-02-22
DK0569795T3 (da) 1995-08-28
AU3710693A (en) 1993-11-18
SK46693A3 (en) 1994-02-02
NO931534D0 (no) 1993-04-27

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