FI932105A - Sulfonylbensylsubstituerade benso- och pyridopyridoner - Google Patents

Sulfonylbensylsubstituerade benso- och pyridopyridoner Download PDF

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Publication number
FI932105A
FI932105A FI932105A FI932105A FI932105A FI 932105 A FI932105 A FI 932105A FI 932105 A FI932105 A FI 932105A FI 932105 A FI932105 A FI 932105A FI 932105 A FI932105 A FI 932105A
Authority
FI
Finland
Prior art keywords
sulfonylbenyl
pyridopyridoner
benso
substitutes
och
Prior art date
Application number
FI932105A
Other languages
English (en)
Other versions
FI932105A0 (fi
Inventor
Juergen Dressel
Peter Fey
Rudolf H Hanko
Walter Huebsch
Thomas Kraemer
Ulrich E Mueller
Matthias Mueller-Gliemann
Martin Beuck
Stanislav Kazda
Stefan Wohlfeil
Andreas Knorr
Johannes-Peter Stasch
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of FI932105A0 publication Critical patent/FI932105A0/fi
Publication of FI932105A publication Critical patent/FI932105A/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C07D217/24—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
FI932105A 1992-05-12 1993-05-10 Sulfonylbensylsubstituerade benso- och pyridopyridoner FI932105A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4215587A DE4215587A1 (de) 1992-05-12 1992-05-12 Sulfonylbenzyl-substituierte Benzo- und Pyridopyridone

Publications (2)

Publication Number Publication Date
FI932105A0 FI932105A0 (fi) 1993-05-10
FI932105A true FI932105A (fi) 1993-11-13

Family

ID=6458654

Family Applications (1)

Application Number Title Priority Date Filing Date
FI932105A FI932105A (fi) 1992-05-12 1993-05-10 Sulfonylbensylsubstituerade benso- och pyridopyridoner

Country Status (21)

Country Link
US (1) US5354749A (fi)
EP (1) EP0569795B1 (fi)
JP (1) JPH0649031A (fi)
KR (1) KR930023362A (fi)
CN (1) CN1080923A (fi)
AT (1) ATE121086T1 (fi)
AU (1) AU3710693A (fi)
CA (1) CA2095801A1 (fi)
CZ (1) CZ72393A3 (fi)
DE (2) DE4215587A1 (fi)
DK (1) DK0569795T3 (fi)
ES (1) ES2072784T3 (fi)
FI (1) FI932105A (fi)
GR (1) GR3015836T3 (fi)
HU (1) HU9301366D0 (fi)
IL (1) IL105646A0 (fi)
MX (1) MX9302461A (fi)
NO (1) NO931534L (fi)
PL (1) PL298890A1 (fi)
SK (1) SK46693A3 (fi)
ZA (1) ZA933273B (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4301900A1 (de) * 1993-01-25 1994-07-28 Bayer Ag 2-Oxochinolin-1-yl-methylphenylessigsäurederivate
TW263498B (fi) * 1993-11-10 1995-11-21 Takeda Pharm Industry Co Ltd
WO2006045096A2 (en) * 2004-10-20 2006-04-27 Resverlogix Corp. Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases
CA2617213C (en) 2005-07-29 2014-01-28 Resverlogix Corp. Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
KR101444489B1 (ko) * 2007-02-01 2014-09-24 리스버로직스 코퍼레이션 심혈관 질환을 예방 및 치료하기 위한 화합물
PT2346837E (pt) 2008-06-26 2015-04-02 Resverlogix Corp Métodos de preparação de derivados de quinazolinona
CA2747925A1 (en) 2008-12-23 2010-07-01 F. Hoffmann-La Roche Ag Dihydropyridone amides as p2x7 modulators
SG172382A1 (en) 2008-12-23 2011-07-28 Hoffmann La Roche Dihydropyridone ureas as p2x7 modulators
MX2011006843A (es) 2008-12-23 2011-08-04 Hoffmann La Roche Dihidropiridona-amidas como moduladores de p2x7.
AU2009331659B2 (en) 2008-12-23 2015-09-03 F. Hoffmann-La Roche Ag Dihydropyridone amides as P2X7 modulators
US8153808B2 (en) 2008-12-23 2012-04-10 Roche Palo Alto Llc Dihydropyridone amides as P2X7 modulators
ES2542835T3 (es) 2009-01-08 2015-08-12 Resverlogix Corporation Compuestos para la prevención y el tratamiento de enfermedades cardiovasculares
WO2010106436A2 (en) 2009-03-18 2010-09-23 Resverlogix Corp. Novel anti-inflammatory agents
EP2421533B1 (en) 2009-04-22 2018-10-17 Resverlogix Corp. Novel anti-inflammatory agents
RS58911B1 (sr) 2011-11-01 2019-08-30 Resverlogix Corp Oralne formulacije sa trenutnim otpuštanjem za supstituisane hinazolinone
WO2014080290A2 (en) 2012-11-21 2014-05-30 Rvx Therapeutics Inc. Cyclic amines as bromodomain inhibitors
US9765039B2 (en) 2012-11-21 2017-09-19 Zenith Epigenetics Ltd. Biaryl derivatives as bromodomain inhibitors
KR20150096794A (ko) 2012-12-21 2015-08-25 제니쓰 에피제네틱스 코포레이션 브로모도메인 저해제로서의 신규한 헤테로사이클릭 화합물
CA2977308A1 (en) 2015-03-13 2016-09-22 Resverlogix Corp. Compositions and therapeutic methods for the treatment of complement-associated diseases
CN110327347B (zh) * 2019-08-16 2021-06-01 陕西科技大学 G-749在制备抗真菌药物中的应用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2314985A1 (de) * 1973-03-26 1974-10-17 Hoechst Ag 1-(imidazol-1-yl)-isochinoline und verfahren zu ihrer herstellung
JPS6145820A (ja) * 1984-03-07 1986-03-05 Nippon Piston Ring Co Ltd 粉末成形体の定間隔整列方法及びその整列装置
DE3800785A1 (de) * 1988-01-09 1989-07-20 Hoechst Ag Substituierte 7-(pyridazin-5-yl)-3,5-dihydroxyheptan(en)- saeuren, ihre entsprechenden (delta)-lactone bzw. derivate, verfahren zu ihrer herstellung, ihre verwendung als arzneimittel, pharmazeutische praeparate und zwischenprodukte
IE64514B1 (en) * 1989-05-23 1995-08-09 Zeneca Ltd Azaindenes
GB8911854D0 (en) * 1989-05-23 1989-07-12 Ici Plc Heterocyclic compounds
EP0403159B1 (en) * 1989-06-14 2000-03-01 Smithkline Beecham Corporation Imidazolyl-alkenoic acids
CA2018443A1 (en) * 1989-06-14 1990-12-14 Joseph A. Finkelstein Imidazolyl-alkenoic acids
US5164407A (en) * 1989-07-03 1992-11-17 Merck & Co., Inc. Substituted imidazo-fused 5-membered ring heterocycles and their use as angiotensin ii antagonsists
EP0485410A1 (en) * 1989-07-06 1992-05-20 The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern A detector for monitoring low molecular weight compounds
NZ234854A (en) * 1989-08-11 1993-02-25 Ici Plc Quinoline derivatives, preparation, intermediates and pharmaceutical compositions thereof
CA2027937A1 (en) * 1989-10-25 1991-04-26 Richard M. Keenan Substituted 5-¬ (tetrazolyl)alkenyl|imidazoles
JP2860676B2 (ja) * 1989-12-07 1999-02-24 川研ファインケミカル株式会社 １―イソキノリン類の製造方法
GB9010394D0 (en) * 1990-05-09 1990-06-27 Ici Plc Heterocyclic compounds
IE912956A1 (en) * 1990-09-10 1992-03-11 Abbott Lab Angiotensin ii receptor antagonists
GB9025123D0 (en) * 1990-11-19 1991-01-02 Ici Plc Nitrogen compounds
US5162325A (en) * 1991-05-07 1992-11-10 Merck & Co., Inc. Angiotensin ii antagonists incorporating a substituted benzyl element
US5162340A (en) * 1991-05-10 1992-11-10 Merck & Co., Inc. Substituted 1-(2h)-isoquinolinones bearing acidic functional groups as angiotensin ii antagonists
US5256667A (en) * 1991-09-25 1993-10-26 Merck & Co., Inc. Quinazolinones and pyridopyrimidinones
DE4206045A1 (de) * 1992-02-27 1993-09-02 Bayer Ag Sulfonylbenzyl substituierte pyridone

Also Published As

Publication number Publication date
DE59300135D1 (de) 1995-05-18
GR3015836T3 (en) 1995-07-31
NO931534L (no) 1993-11-15
NO931534D0 (no) 1993-04-27
CA2095801A1 (en) 1993-11-13
ES2072784T3 (es) 1995-07-16
US5354749A (en) 1994-10-11
PL298890A1 (en) 1994-01-10
CZ72393A3 (en) 1993-12-15
DK0569795T3 (da) 1995-08-28
SK46693A3 (en) 1994-02-02
KR930023362A (ko) 1993-12-18
IL105646A0 (en) 1993-09-22
EP0569795B1 (de) 1995-04-12
ZA933273B (en) 1993-11-29
JPH0649031A (ja) 1994-02-22
AU3710693A (en) 1993-11-18
EP0569795A1 (de) 1993-11-18
FI932105A0 (fi) 1993-05-10
CN1080923A (zh) 1994-01-19
MX9302461A (es) 1994-06-30
ATE121086T1 (de) 1995-04-15
DE4215587A1 (de) 1993-11-18
HU9301366D0 (en) 1993-09-28

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