ES2044970T3 - Procedimiento para la obtencion de compuestos hidrogenados del acido 1-benzooxacicloalquil-piridincarboxilico. - Google Patents

Procedimiento para la obtencion de compuestos hidrogenados del acido 1-benzooxacicloalquil-piridincarboxilico.

Info

Publication number
ES2044970T3
ES2044970T3 ES87810350T ES87810350T ES2044970T3 ES 2044970 T3 ES2044970 T3 ES 2044970T3 ES 87810350 T ES87810350 T ES 87810350T ES 87810350 T ES87810350 T ES 87810350T ES 2044970 T3 ES2044970 T3 ES 2044970T3
Authority
ES
Spain
Prior art keywords
denotes
alkylcarbamyl
oxygen atom
optionally
dilower
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES87810350T
Other languages
English (en)
Inventor
Wolfgang Dr Frostl
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of ES2044970T3 publication Critical patent/ES2044970T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

LA INVENCION SE REFIERE A NUEVOS COMPUESTOS HIDRATADOS DEL ACIDO 1-BENZOOXACICLO-ALQUI-PIRIDIN CARBOXILICO DE LA FORMULA (I) EN LA QUE R1,R2,R3,ALK,N,X E Y SON COMO SE HAN DEFINIDO EN LA MEMORIA Y EN LAS REIVINDICACIONES, ASI COMO A SUS FORMAS TAUTOMERAS Y/O SALES. ESTOS COMPUESTOS PUEDEN UTILIZARSE COMO PRINCIPIOS ACTIVOS FARMACEUTICOS Y SE PUEDEN PREPARAR DE UNA MANERA EN SI CONOCIDA.
ES87810350T 1986-06-26 1987-06-22 Procedimiento para la obtencion de compuestos hidrogenados del acido 1-benzooxacicloalquil-piridincarboxilico. Expired - Lifetime ES2044970T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH258886 1986-06-26

Publications (1)

Publication Number Publication Date
ES2044970T3 true ES2044970T3 (es) 1994-01-16

Family

ID=4237161

Family Applications (1)

Application Number Title Priority Date Filing Date
ES87810350T Expired - Lifetime ES2044970T3 (es) 1986-06-26 1987-06-22 Procedimiento para la obtencion de compuestos hidrogenados del acido 1-benzooxacicloalquil-piridincarboxilico.

Country Status (16)

Country Link
EP (1) EP0252005B1 (es)
JP (1) JPH0699420B2 (es)
AT (1) ATE65084T1 (es)
AU (1) AU617988B2 (es)
CA (1) CA1322553C (es)
CY (1) CY1783A (es)
DD (1) DD279674A5 (es)
DE (1) DE3771280D1 (es)
DK (1) DK325587A (es)
ES (1) ES2044970T3 (es)
FI (1) FI91064C (es)
GR (1) GR3002308T3 (es)
HK (1) HK134994A (es)
HU (1) HU207061B (es)
IE (1) IE59881B1 (es)
PT (1) PT85157B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0322361A3 (de) * 1987-12-23 1990-01-24 Ciba-Geigy Ag Weitere hydrierte 1-Benzooxacycloalkylpyridincarbonsäureverbindungen
US5342616A (en) * 1988-06-20 1994-08-30 The Wellcome Foundation Limited Method of administering tissue plasminogen activator
DE3901814A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
EP0389425B1 (de) * 1989-03-22 1995-04-26 Ciba-Geigy Ag Neue Benzothiopyranylamine
US5189179A (en) 1990-08-29 1993-02-23 Merrell Dow Pharmaceuticals Inc. Serotonin 5ht1a agonists
US5221745A (en) * 1991-06-21 1993-06-22 American Home Products Corp. Psychotropic piperidinylmethyl benzodioxans
US5182292A (en) * 1991-06-21 1993-01-26 American Home Products Corporation Psychotropic piperidinylmethyl benzodioxans
US5212170A (en) * 1991-06-21 1993-05-18 American Home Products Corporation Psychotropic piperidinylmethyl benzodioxans
US5240943A (en) * 1991-12-19 1993-08-31 G. D. Searle & Co. Benzopyran class iii antiarrhythmic agents
FR2694005B1 (fr) * 1992-07-21 1994-08-26 Adir Nouvelles aminoalkylchromones, leurs procédés de préparation et les compositions pharmaceutiques qui les contiennent.
JP3546657B2 (ja) * 1997-08-29 2004-07-28 株式会社トヨトミ 給湯機の缶体構造
JP2008524276A (ja) * 2004-12-20 2008-07-10 エフ．ホフマン−ラ ロシュ アーゲー ４−アミノピペリジン誘導体
US10258598B2 (en) 2014-12-05 2019-04-16 Semmelweis University Compounds for use in the prevention or treatment of cancer

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1366479A (fr) * 1962-08-20 1964-07-10 Res Lab Dr C Janssen Nv Procédé de production de nouveaux dérivés de la pipéridine et de leurs sels
GB1520801A (en) * 1975-01-16 1978-08-09 Lafon Labor Benzodioxanyl and benzofuranylmethylamines
AU552050B2 (en) * 1981-05-26 1986-05-22 Smithkline Beckman Corporation N-substituted azeheterocyclic carboxylic acids and their esters
CA1183847A (en) * 1981-10-01 1985-03-12 Georges Van Daele N-(3-hydroxy-4-piperidinyl)benzamide derivatives
FR2524887A1 (fr) * 1982-04-08 1983-10-14 Bouchara Emile Nouvelles cyanoguanidines, leur procede d'obtention et les compositions pharmaceutiques en renfermant
DE3411993A1 (de) * 1984-03-31 1985-10-10 Bayer Ag, 5090 Leverkusen Substituierte benzopyrane, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimittel
JPH0816108B2 (ja) * 1986-02-21 1996-02-21 株式会社クラレ ３，４−ジヒドロ−２ｈ−ベンゾピラン誘導体及びその医薬用途

Also Published As

Publication number Publication date
DK325587D0 (da) 1987-06-25
PT85157A (en) 1987-07-01
EP0252005B1 (de) 1991-07-10
DD279674A5 (de) 1990-06-13
HK134994A (en) 1994-12-09
JPS638382A (ja) 1988-01-14
GR3002308T3 (en) 1992-12-30
CA1322553C (en) 1993-09-28
HUT48622A (en) 1989-06-28
IE871694L (en) 1987-12-26
DK325587A (da) 1987-12-27
FI872807A0 (fi) 1987-06-24
DE3771280D1 (de) 1991-08-14
FI91064C (fi) 1994-05-10
HU207061B (en) 1993-03-01
EP0252005A1 (de) 1988-01-07
IE59881B1 (en) 1994-04-20
ATE65084T1 (de) 1991-07-15
AU8125587A (en) 1989-05-18
AU617988B2 (en) 1991-12-12
JPH0699420B2 (ja) 1994-12-07
PT85157B (pt) 1990-03-30
FI91064B (fi) 1994-01-31
CY1783A (en) 1995-10-20
FI872807A (fi) 1987-12-27

Similar Documents

Publication Publication Date Title
ES2044970T3 (es) Procedimiento para la obtencion de compuestos hidrogenados del acido 1-benzooxacicloalquil-piridincarboxilico.
AU557691B2 (en) 2-penem antibiotics and their oxa-aza-, and carba analogues
ATE99685T1 (de) Oxadiazolylalkylpurin-derivate, ihre herstellung und ihre verwendung in pharmazeutischen mitteln.
DK192987A (da) Kromoglycinsyrederivater, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat
DE3070847D1 (en) Benzazepine derivatives, process and intermediates for their preparation, their use and pharmaceutical compositions containing them
DE3576075D1 (de) 5-alkyl-1-phenyl-2-piperazinoalkylpyrazolin-3-on-verbindungen sowie verfahren und zwischenprodukte zu ihrer herstellung und diese verbindungen enthaltende arzneimittel.
ATE79624T1 (de) 3h-1,2,3-triazolo(4,5-d>pyrimidine.
IE822310L (en) Triazoloquinazolone derivatives
ES480112A1 (es) Procedimiento para la preparacion de nuevos derivados de 2- iminoimidazolidina.
DE3770321D1 (de) 1,5-benzothiazepinderivate, deren herstellung und deren verwendung in der therapie.
DE69014385D1 (de) Hydroxyalkylfuranyl-Derivate.
DK0461574T3 (da) Lægemidler indeholdende 3,7-diazabicyclo(3,3,1)-nonanforbindelser
ATE139441T1 (de) Verwendung von 2-iminothiazolidin-4-onderivaten als neuartige arzneimittelwirkstoffe
ATE37368T1 (de) Benzothiazolon-derivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen.
NO872982L (no) Nye tetracykliske indolderivater.
ATE33837T1 (de) Azolylmethylcycloacetale, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel.
ES464773A1 (es) Procedimiento para la preparacion de 2,9-dioxatriciclo (4,3,1,03,7)decanos.
SE7905631L (sv) Nya oxotiaforeningar
SE7909980L (sv) I-amino-indolin-derivat, deras framstellning och farmaceutiska kompositioner innehallande desamma

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 252005

Country of ref document: ES