CY1783A - Hydrogenated 1-benzooxacycloalkyl-pyridine carboxylic-acid compounds - Google Patents
Hydrogenated 1-benzooxacycloalkyl-pyridine carboxylic-acid compoundsInfo
- Publication number
- CY1783A CY1783A CY178395A CY178395A CY1783A CY 1783 A CY1783 A CY 1783A CY 178395 A CY178395 A CY 178395A CY 178395 A CY178395 A CY 178395A CY 1783 A CY1783 A CY 1783A
- Authority
- CY
- Cyprus
- Prior art keywords
- denotes
- alkylcarbamyl
- oxygen atom
- optionally
- acid compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
- C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
- C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
- Pyrane Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyridine Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Novel hydrogenated 1-benzooxacycloalkylpyridinecarboxylic acid compounds of the formula <IMAGE> in which either R1 denotes carboxyl, lower alkoxycarbonyl, carbamyl, N-lower alkylcarbamyl, N,N-dilower alkylcarbamyl or optionally acylated hydroxymethyl and R2 denotes hydrogen, an optionally etherified or acylated hydroxyl group or an optionally acylated amino group or R1 denotes hydrogen and R2 represents carboxyl, lower alkoxycarbonyl, carbamyl, N-lower alkylcarbamyl, N,N-dilower alkylcarbamyl or optionally acylated hydroxymethyl, R3 denotes hydrogen or lower alkyl, alk denotes lower alkylene or lower alkylidene, the ring A is unsubstituted or mono- or polysubstituted by hydroxyl, lower alkoxy, lower alkanoyloxy, halogen, lower alkyl and/or trifluoromethyl, the dashed line is intended to express that a single bond or a double bond is present and either X and Y in each case denotes an oxygen atom and n represents 1 or X represents a methylene group, Y denotes an oxygen atom and n represents 1 or X represents an oxygen atom, Y denotes a methylene group and n represents 1 or X represents a direct bond, Y represents an oxygen atom and n represents 2, and their tautomers and/or salts are described. These compounds can be used as pharmaceutical active substances and can be prepared in a manner known per se.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH258886 | 1986-06-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1783A true CY1783A (en) | 1995-10-20 |
Family
ID=4237161
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY178395A CY1783A (en) | 1986-06-26 | 1995-10-20 | Hydrogenated 1-benzooxacycloalkyl-pyridine carboxylic-acid compounds |
Country Status (16)
Country | Link |
---|---|
EP (1) | EP0252005B1 (en) |
JP (1) | JPH0699420B2 (en) |
AT (1) | ATE65084T1 (en) |
AU (1) | AU617988B2 (en) |
CA (1) | CA1322553C (en) |
CY (1) | CY1783A (en) |
DD (1) | DD279674A5 (en) |
DE (1) | DE3771280D1 (en) |
DK (1) | DK325587A (en) |
ES (1) | ES2044970T3 (en) |
FI (1) | FI91064C (en) |
GR (1) | GR3002308T3 (en) |
HK (1) | HK134994A (en) |
HU (1) | HU207061B (en) |
IE (1) | IE59881B1 (en) |
PT (1) | PT85157B (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0322361A3 (en) * | 1987-12-23 | 1990-01-24 | Ciba-Geigy Ag | Hydrogenated 1-benzooxacycloalkyl pyridine-carboxylic-acid compounds |
US5342616A (en) * | 1988-06-20 | 1994-08-30 | The Wellcome Foundation Limited | Method of administering tissue plasminogen activator |
DE3901814A1 (en) * | 1988-07-28 | 1990-02-01 | Bayer Ag | SUBSTITUTED AMINOMETHYLZETRALINE AND ITS HETEROCYCLIC ANALOG |
EP0389425B1 (en) * | 1989-03-22 | 1995-04-26 | Ciba-Geigy Ag | Benzotiopyranyl amines |
US5189179A (en) | 1990-08-29 | 1993-02-23 | Merrell Dow Pharmaceuticals Inc. | Serotonin 5ht1a agonists |
US5221745A (en) * | 1991-06-21 | 1993-06-22 | American Home Products Corp. | Psychotropic piperidinylmethyl benzodioxans |
US5182292A (en) * | 1991-06-21 | 1993-01-26 | American Home Products Corporation | Psychotropic piperidinylmethyl benzodioxans |
US5212170A (en) * | 1991-06-21 | 1993-05-18 | American Home Products Corporation | Psychotropic piperidinylmethyl benzodioxans |
US5240943A (en) * | 1991-12-19 | 1993-08-31 | G. D. Searle & Co. | Benzopyran class iii antiarrhythmic agents |
FR2694005B1 (en) * | 1992-07-21 | 1994-08-26 | Adir | New aminoalkylchromones, methods for their preparation and pharmaceutical compositions containing them. |
JP3546657B2 (en) * | 1997-08-29 | 2004-07-28 | 株式会社トヨトミ | Water heater can body structure |
JP2008524276A (en) * | 2004-12-20 | 2008-07-10 | エフ.ホフマン−ラ ロシュ アーゲー | 4-aminopiperidine derivatives |
US10258598B2 (en) | 2014-12-05 | 2019-04-16 | Semmelweis University | Compounds for use in the prevention or treatment of cancer |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1366479A (en) * | 1962-08-20 | 1964-07-10 | Res Lab Dr C Janssen Nv | Process for the production of novel piperidine derivatives and their salts |
GB1520801A (en) * | 1975-01-16 | 1978-08-09 | Lafon Labor | Benzodioxanyl and benzofuranylmethylamines |
AU552050B2 (en) * | 1981-05-26 | 1986-05-22 | Smithkline Beckman Corporation | N-substituted azeheterocyclic carboxylic acids and their esters |
CA1183847A (en) * | 1981-10-01 | 1985-03-12 | Georges Van Daele | N-(3-hydroxy-4-piperidinyl)benzamide derivatives |
FR2524887A1 (en) * | 1982-04-08 | 1983-10-14 | Bouchara Emile | NOVEL CYANOGUANIDINES, PROCESS FOR OBTAINING THEM AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME |
DE3411993A1 (en) * | 1984-03-31 | 1985-10-10 | Bayer Ag, 5090 Leverkusen | SUBSTITUTED BENZOPYRANS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE IN MEDICINAL PRODUCTS |
JPH0816108B2 (en) * | 1986-02-21 | 1996-02-21 | 株式会社クラレ | 3,4-Dihydro-2H-benzopyran derivative and its pharmaceutical use |
-
1987
- 1987-06-22 AT AT87810350T patent/ATE65084T1/en not_active IP Right Cessation
- 1987-06-22 ES ES87810350T patent/ES2044970T3/en not_active Expired - Lifetime
- 1987-06-22 EP EP87810350A patent/EP0252005B1/en not_active Expired - Lifetime
- 1987-06-22 DE DE8787810350T patent/DE3771280D1/en not_active Expired - Lifetime
- 1987-06-24 CA CA000540433A patent/CA1322553C/en not_active Expired - Fee Related
- 1987-06-24 PT PT85157A patent/PT85157B/en not_active IP Right Cessation
- 1987-06-24 FI FI872807A patent/FI91064C/en not_active IP Right Cessation
- 1987-06-25 DK DK325587A patent/DK325587A/en not_active Application Discontinuation
- 1987-06-25 JP JP62156698A patent/JPH0699420B2/en not_active Expired - Lifetime
- 1987-06-25 IE IE169487A patent/IE59881B1/en not_active IP Right Cessation
- 1987-11-16 AU AU81255/87A patent/AU617988B2/en not_active Ceased
- 1987-11-17 DD DD87309128A patent/DD279674A5/en not_active IP Right Cessation
- 1987-11-25 HU HU875303A patent/HU207061B/en not_active IP Right Cessation
-
1991
- 1991-07-12 GR GR91400907T patent/GR3002308T3/en unknown
-
1994
- 1994-12-01 HK HK134994A patent/HK134994A/en not_active IP Right Cessation
-
1995
- 1995-10-20 CY CY178395A patent/CY1783A/en unknown
Also Published As
Publication number | Publication date |
---|---|
DK325587D0 (en) | 1987-06-25 |
PT85157A (en) | 1987-07-01 |
EP0252005B1 (en) | 1991-07-10 |
DD279674A5 (en) | 1990-06-13 |
HK134994A (en) | 1994-12-09 |
JPS638382A (en) | 1988-01-14 |
ES2044970T3 (en) | 1994-01-16 |
GR3002308T3 (en) | 1992-12-30 |
CA1322553C (en) | 1993-09-28 |
HUT48622A (en) | 1989-06-28 |
IE871694L (en) | 1987-12-26 |
DK325587A (en) | 1987-12-27 |
FI872807A0 (en) | 1987-06-24 |
DE3771280D1 (en) | 1991-08-14 |
FI91064C (en) | 1994-05-10 |
HU207061B (en) | 1993-03-01 |
EP0252005A1 (en) | 1988-01-07 |
IE59881B1 (en) | 1994-04-20 |
ATE65084T1 (en) | 1991-07-15 |
AU8125587A (en) | 1989-05-18 |
AU617988B2 (en) | 1991-12-12 |
JPH0699420B2 (en) | 1994-12-07 |
PT85157B (en) | 1990-03-30 |
FI91064B (en) | 1994-01-31 |
FI872807A (en) | 1987-12-27 |
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