ES481936A2 - Novel oxothia compounds, processes for their preparation, pharmaceutical preparations containing these compounds and their use as a medicinal active compound - Google Patents

Novel oxothia compounds, processes for their preparation, pharmaceutical preparations containing these compounds and their use as a medicinal active compound

Info

Publication number
ES481936A2
ES481936A2 ES481936A ES481936A ES481936A2 ES 481936 A2 ES481936 A2 ES 481936A2 ES 481936 A ES481936 A ES 481936A ES 481936 A ES481936 A ES 481936A ES 481936 A2 ES481936 A2 ES 481936A2
Authority
ES
Spain
Prior art keywords
compounds
pharmaceutical preparations
novel
processes
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES481936A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES481936A2 publication Critical patent/ES481936A2/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30Hetero atoms other than halogen
    • C07D333/36Nitrogen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Abstract

2-Oxo-2,3-dihydro- benzo[b]thiophen compounds of the formula < IMAGE > in which Ph is a substituted or unsubstituted 1,2-phenylene radical, X is oxygen or sulfur, R1 is a substituted or unsubstituted heteroaryl radical bonded via a carbon atom and R2 is hydrogen, and their salts with bases have peripheral analgesic properties. They can be prepared by methods known per se and can be used as the active ingredient in pharmaceutical preparations.
ES481936A 1978-06-29 1979-06-26 Novel oxothia compounds, processes for their preparation, pharmaceutical preparations containing these compounds and their use as a medicinal active compound Expired ES481936A2 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH710378A CH634840A5 (en) 1978-06-29 1978-06-29 2-OXO-2,3-DIHYDRO-BENZO (B) THIOPHENE COMPOUND AND PHARMACEUTICAL PREPARATIONS MADE THEREOF.

Publications (1)

Publication Number Publication Date
ES481936A2 true ES481936A2 (en) 1980-06-16

Family

ID=4320005

Family Applications (1)

Application Number Title Priority Date Filing Date
ES481936A Expired ES481936A2 (en) 1978-06-29 1979-06-26 Novel oxothia compounds, processes for their preparation, pharmaceutical preparations containing these compounds and their use as a medicinal active compound

Country Status (26)

Country Link
JP (1) JPS559075A (en)
AR (1) AR231540A1 (en)
AT (3) AT374199B (en)
AU (1) AU531535B2 (en)
BE (1) BE877339R (en)
CA (1) CA1125761A (en)
CH (1) CH634840A5 (en)
CY (1) CY1288A (en)
DD (1) DD144544A6 (en)
DE (1) DE2924496A1 (en)
DK (1) DK152047C (en)
ES (1) ES481936A2 (en)
FI (1) FI792011A (en)
FR (1) FR2429792A2 (en)
GB (1) GB2024220B (en)
GR (1) GR82335B (en)
HK (1) HK42585A (en)
HU (1) HU181663B (en)
IE (1) IE48767B1 (en)
MY (1) MY8500212A (en)
NL (1) NL7905084A (en)
NO (1) NO151323C (en)
PL (3) PL216377A3 (en)
SE (1) SE445737B (en)
SG (1) SG15985G (en)
ZA (1) ZA793230B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4800211A (en) * 1986-08-18 1989-01-24 Merck & Co., Inc. 5-methylthio-3-hydroxybenzo [b]thiophene-2-carboxamide derivatives as cyclooxygenase and lipoxygenase inhibitors
JP2004501910A (en) * 2000-06-28 2004-01-22 イーライ・リリー・アンド・カンパニー Novel sPLA2 inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2713584C2 (en) * 1976-04-09 1986-09-04 Ciba-Geigy Ag, Basel Benzo [b] thiophenecarboxamides, processes for their preparation and pharmaceutical preparations containing them
JPS6218556A (en) * 1985-07-18 1987-01-27 Fuji Photo Film Co Ltd Silver halide color photographic sensitive material

Also Published As

Publication number Publication date
AU4850979A (en) 1980-02-07
AT373598B (en) 1984-02-10
NL7905084A (en) 1980-01-03
GB2024220B (en) 1982-12-01
JPS559075A (en) 1980-01-22
CY1288A (en) 1985-07-05
ATA451579A (en) 1983-08-15
BE877339R (en) 1979-12-28
FR2429792A2 (en) 1980-01-25
ATA451679A (en) 1983-06-15
SG15985G (en) 1985-08-16
IE48767B1 (en) 1985-05-15
AT374199B (en) 1984-03-26
DE2924496C2 (en) 1989-12-21
FR2429792B2 (en) 1983-02-04
HU181663B (en) 1983-10-28
PL216377A3 (en) 1980-03-24
DD144544A6 (en) 1980-10-22
DK274279A (en) 1979-12-30
CH634840A5 (en) 1983-02-28
DK152047C (en) 1988-08-08
AT373597B (en) 1984-02-10
ATA451779A (en) 1983-06-15
ZA793230B (en) 1980-06-25
SE7905631L (en) 1979-12-30
JPH0215549B2 (en) 1990-04-12
IE791205L (en) 1979-12-29
AU531535B2 (en) 1983-08-25
FI792011A (en) 1979-12-30
NO151323B (en) 1984-12-10
MY8500212A (en) 1985-12-31
PL216376A3 (en) 1980-03-24
AR231540A1 (en) 1984-12-28
CA1125761A (en) 1982-06-15
GR82335B (en) 1984-12-13
GB2024220A (en) 1980-01-09
HK42585A (en) 1985-06-07
PL216378A3 (en) 1980-03-24
SE445737B (en) 1986-07-14
NO151323C (en) 1985-03-20
DE2924496A1 (en) 1980-01-17
DK152047B (en) 1988-01-25
NO792178L (en) 1980-01-03

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