SE7905631L - NEW OXOTIA ASSOCIATIONS - Google Patents

NEW OXOTIA ASSOCIATIONS

Info

Publication number
SE7905631L
SE7905631L SE7905631A SE7905631A SE7905631L SE 7905631 L SE7905631 L SE 7905631L SE 7905631 A SE7905631 A SE 7905631A SE 7905631 A SE7905631 A SE 7905631A SE 7905631 L SE7905631 L SE 7905631L
Authority
SE
Sweden
Prior art keywords
oxotia
associations
new
substituted
unsubstituted
Prior art date
Application number
SE7905631A
Other languages
Swedish (sv)
Other versions
SE445737B (en
Inventor
R Bernasconi
P G Ferrini
R Goschke
J Gosteli
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of SE7905631L publication Critical patent/SE7905631L/en
Publication of SE445737B publication Critical patent/SE445737B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/30—Hetero atoms other than halogen
    • C07D333/36—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D333/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

2-Oxo-2,3-dihydro- benzo[b]thiophen compounds of the formula <IMAGE> in which Ph is a substituted or unsubstituted 1,2-phenylene radical, X is oxygen or sulfur, R1 is a substituted or unsubstituted heteroaryl radical bonded via a carbon atom and R2 is hydrogen, and their salts with bases have peripheral analgesic properties. They can be prepared by methods known per se and can be used as the active ingredient in pharmaceutical preparations.
SE7905631A 1978-06-29 1979-06-27 PROCEDURE FOR THE PREPARATION OF N- (2-TIENYL) -2-OXO-2,3-DIHYDRO-BENZO / B / THIOFEN-3-CARBOXAMIDE SE445737B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH710378A CH634840A5 (en) 1978-06-29 1978-06-29 2-OXO-2,3-DIHYDRO-BENZO (B) THIOPHENE COMPOUND AND PHARMACEUTICAL PREPARATIONS MADE THEREOF.

Publications (2)

Publication Number Publication Date
SE7905631L true SE7905631L (en) 1979-12-30
SE445737B SE445737B (en) 1986-07-14

Family

ID=4320005

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7905631A SE445737B (en) 1978-06-29 1979-06-27 PROCEDURE FOR THE PREPARATION OF N- (2-TIENYL) -2-OXO-2,3-DIHYDRO-BENZO / B / THIOFEN-3-CARBOXAMIDE

Country Status (26)

Country Link
JP (1) JPS559075A (en)
AR (1) AR231540A1 (en)
AT (3) AT373597B (en)
AU (1) AU531535B2 (en)
BE (1) BE877339R (en)
CA (1) CA1125761A (en)
CH (1) CH634840A5 (en)
CY (1) CY1288A (en)
DD (1) DD144544A6 (en)
DE (1) DE2924496A1 (en)
DK (1) DK152047C (en)
ES (1) ES481936A2 (en)
FI (1) FI792011A (en)
FR (1) FR2429792A2 (en)
GB (1) GB2024220B (en)
GR (1) GR82335B (en)
HK (1) HK42585A (en)
HU (1) HU181663B (en)
IE (1) IE48767B1 (en)
MY (1) MY8500212A (en)
NL (1) NL7905084A (en)
NO (1) NO151323C (en)
PL (3) PL216376A3 (en)
SE (1) SE445737B (en)
SG (1) SG15985G (en)
ZA (1) ZA793230B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4800211A (en) * 1986-08-18 1989-01-24 Merck & Co., Inc. 5-methylthio-3-hydroxybenzo [b]thiophene-2-carboxamide derivatives as cyclooxygenase and lipoxygenase inhibitors
JP2004501910A (en) 2000-06-28 2004-01-22 イーライ・リリー・アンド・カンパニー Novel sPLA2 inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2713584C2 (en) * 1976-04-09 1986-09-04 Ciba-Geigy Ag, Basel Benzo [b] thiophenecarboxamides, processes for their preparation and pharmaceutical preparations containing them
JPS6218556A (en) * 1985-07-18 1987-01-27 Fuji Photo Film Co Ltd Silver halide color photographic sensitive material

Also Published As

Publication number Publication date
DD144544A6 (en) 1980-10-22
ATA451579A (en) 1983-08-15
FR2429792B2 (en) 1983-02-04
JPH0215549B2 (en) 1990-04-12
ZA793230B (en) 1980-06-25
ATA451779A (en) 1983-06-15
ES481936A2 (en) 1980-06-16
CY1288A (en) 1985-07-05
GB2024220B (en) 1982-12-01
AT373598B (en) 1984-02-10
DK152047B (en) 1988-01-25
AU531535B2 (en) 1983-08-25
FR2429792A2 (en) 1980-01-25
GB2024220A (en) 1980-01-09
AT374199B (en) 1984-03-26
PL216377A3 (en) 1980-03-24
PL216376A3 (en) 1980-03-24
AT373597B (en) 1984-02-10
HK42585A (en) 1985-06-07
PL216378A3 (en) 1980-03-24
JPS559075A (en) 1980-01-22
AU4850979A (en) 1980-02-07
DE2924496A1 (en) 1980-01-17
NO151323C (en) 1985-03-20
NO792178L (en) 1980-01-03
MY8500212A (en) 1985-12-31
IE791205L (en) 1979-12-29
BE877339R (en) 1979-12-28
AR231540A1 (en) 1984-12-28
NO151323B (en) 1984-12-10
CA1125761A (en) 1982-06-15
FI792011A (en) 1979-12-30
DK152047C (en) 1988-08-08
HU181663B (en) 1983-10-28
NL7905084A (en) 1980-01-03
IE48767B1 (en) 1985-05-15
SE445737B (en) 1986-07-14
GR82335B (en) 1984-12-13
ATA451679A (en) 1983-06-15
SG15985G (en) 1985-08-16
DK274279A (en) 1979-12-30
DE2924496C2 (en) 1989-12-21
CH634840A5 (en) 1983-02-28

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