LT3313421T - Kompozicija, apimanti bakterinį blautia hydrogenotrophica kamieną, skirta virškinamojo trakto bakterinės infekcijos gydymui - Google Patents

Kompozicija, apimanti bakterinį blautia hydrogenotrophica kamieną, skirta virškinamojo trakto bakterinės infekcijos gydymui

Info

Publication number
LT3313421T
LT3313421T LTEP17742523.8T LT17742523T LT3313421T LT 3313421 T LT3313421 T LT 3313421T LT 17742523 T LT17742523 T LT 17742523T LT 3313421 T LT3313421 T LT 3313421T
Authority
LT
Lithuania
Prior art keywords
compositions
treatment
gastrointestinal tract
bacterial
blautia hydrogenotrophica
Prior art date
Application number
LTEP17742523.8T
Other languages
English (en)
Inventor
Laureen CROUZET
Chloe HABOUZIT
Annick BERNALIER-DONADILLE
Original Assignee
4D Pharma Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB1612190.7A external-priority patent/GB201612190D0/en
Priority claimed from GBGB1616016.0A external-priority patent/GB201616016D0/en
Priority claimed from GBGB1703548.6A external-priority patent/GB201703548D0/en
Priority claimed from GBGB1703552.8A external-priority patent/GB201703552D0/en
Application filed by 4D Pharma Plc filed Critical 4D Pharma Plc
Publication of LT3313421T publication Critical patent/LT3313421T/lt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/135Bacteria or derivatives thereof, e.g. probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0208Specific bacteria not otherwise provided for
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2200/00Function of food ingredients
    • A23V2200/30Foods, ingredients or supplements having a functional effect on health
    • A23V2200/32Foods, ingredients or supplements having a functional effect on health having an effect on the health of the digestive tract
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K2035/11Medicinal preparations comprising living procariotic cells
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Physiology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
LTEP17742523.8T 2016-07-13 2017-07-13 Kompozicija, apimanti bakterinį blautia hydrogenotrophica kamieną, skirta virškinamojo trakto bakterinės infekcijos gydymui LT3313421T (lt)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GBGB1612190.7A GB201612190D0 (en) 2016-07-13 2016-07-13 Compositions comprising bacterial strains
GBGB1616018.6A GB201616018D0 (en) 2016-07-13 2016-09-20 Compositions comprising bacterial strains
GBGB1616016.0A GB201616016D0 (en) 2016-09-20 2016-09-20 Compositions comprising bacterial strains
GBGB1703548.6A GB201703548D0 (en) 2017-03-06 2017-03-06 Compositions comprising bacterial strains
GBGB1703552.8A GB201703552D0 (en) 2017-03-06 2017-03-06 Compositions comprising bacterial strains
PCT/GB2017/052076 WO2018011593A1 (en) 2016-07-13 2017-07-13 Compositions comprising bacterial strains

Publications (1)

Publication Number Publication Date
LT3313421T true LT3313421T (lt) 2019-04-25

Family

ID=60953493

Family Applications (2)

Application Number Title Priority Date Filing Date
LTEP17742524.6T LT3313422T (lt) 2016-07-13 2017-07-13 Kompozicija, apimanti bakterinį kamieną blautia hydrogenotrophica, skirta panaudoti viduriavimo arba vidurių užkietėjimo gydymui arba prevencijai
LTEP17742523.8T LT3313421T (lt) 2016-07-13 2017-07-13 Kompozicija, apimanti bakterinį blautia hydrogenotrophica kamieną, skirta virškinamojo trakto bakterinės infekcijos gydymui

Family Applications Before (1)

Application Number Title Priority Date Filing Date
LTEP17742524.6T LT3313422T (lt) 2016-07-13 2017-07-13 Kompozicija, apimanti bakterinį kamieną blautia hydrogenotrophica, skirta panaudoti viduriavimo arba vidurių užkietėjimo gydymui arba prevencijai

Country Status (29)

Country Link
US (8) US10086020B2 (lt)
EP (4) EP3517120A1 (lt)
JP (4) JP6494859B2 (lt)
KR (2) KR102060388B1 (lt)
CN (2) CN109789170B (lt)
AU (4) AU2017296126B2 (lt)
BR (2) BR112018075833A2 (lt)
CA (2) CA3028903C (lt)
CO (2) CO2018013557A2 (lt)
CY (2) CY1121766T1 (lt)
DK (2) DK3313422T3 (lt)
ES (2) ES2720263T3 (lt)
HK (2) HK1246681B (lt)
HR (2) HRP20190659T1 (lt)
HU (2) HUE043338T2 (lt)
IL (4) IL263267B (lt)
LT (2) LT3313422T (lt)
MA (2) MA42278B1 (lt)
MD (2) MD3313422T2 (lt)
ME (2) ME03380B (lt)
MX (4) MX2018015761A (lt)
PE (2) PE20190451A1 (lt)
PL (2) PL3313421T3 (lt)
PT (2) PT3313421T (lt)
RS (2) RS58623B1 (lt)
SG (4) SG11201900195RA (lt)
SI (2) SI3313421T1 (lt)
TW (2) TW201821093A (lt)
WO (2) WO2018011593A1 (lt)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
EA035925B1 (ru) 2014-12-23 2020-09-01 4Д Фарма Рисерч Лимитед Полипептид и иммуномодуляция
KR101942955B1 (ko) 2014-12-23 2019-01-28 4디 파마 리서치 리미티드 면역 조정
NZ777234A (en) 2015-06-15 2022-02-25 4D Pharma Res Ltd Compositions comprising bacterial strains
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
LT3240554T (lt) 2015-06-15 2019-11-11 4D Pharma Res Ltd Blautia stercosis ir wexlerae, skirtos naudoti uždegiminių ir autoimuninių ligų gydymui
EP3307288B1 (en) 2015-06-15 2019-07-24 4D Pharma Research Limited Compositions comprising bacterial strains
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
ES2662617T3 (es) 2015-11-20 2018-04-09 4D Pharma Research Limited Composiciones que comprenden cepas bacterianas
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
JP6573639B2 (ja) * 2016-01-26 2019-09-11 富士フイルム株式会社 腸内細菌数抑制剤、食品、及び医薬品
CN108883139B (zh) 2016-03-04 2022-04-26 4D制药有限公司 包含细菌菌株的组合物
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
TW201821093A (zh) 2016-07-13 2018-06-16 英商4D製藥有限公司 包含細菌菌株之組合物
GB201621123D0 (en) * 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
EP3606325B1 (en) 2017-04-03 2024-09-04 Gusto Global, LLC Rational design of microbial-based biotherapeutics
US10843151B2 (en) * 2017-05-09 2020-11-24 Algimate Dental Systems Private Limited Mixing and dispensing apparatus to obtain semi-liquid form of a powder material
CN110913878A (zh) 2017-05-22 2020-03-24 4D制药研究有限公司 包含细菌菌株的组合物
EP3630942B1 (en) 2017-05-24 2022-11-30 4D Pharma Research Limited Compositions comprising bacterial strain
PT3638271T (pt) 2017-06-14 2021-01-05 4D Pharma Res Ltd Composições contendo estirpes bacterianas
DK3804737T3 (da) 2017-06-14 2022-07-25 4D Pharma Res Ltd Sammensætninger omfattende bakteriestammer
WO2018229189A1 (en) 2017-06-14 2018-12-20 4D Pharma Research Limited Compositions comprising bacterial strains
BR112020025123A2 (pt) * 2018-06-19 2021-03-23 4D Pharma Research Ltd forma de dosagem compreendendo um produto bioterapêutico vivo
MA53155A (fr) 2018-07-16 2021-05-26 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
TW202108153A (zh) * 2019-05-10 2021-03-01 英商4D製藥研究有限公司 包含細菌菌株之組成物
CN111304120B (zh) * 2020-02-24 2021-07-23 浙江大学 Blautia sp B2132菌在预防和/或治疗炎症性肠病中的应用
CN114681492B (zh) * 2020-12-28 2024-04-19 中国科学院上海营养与健康研究所 改善代谢性疾病的肠道益生菌及其应用
WO2023014054A1 (ko) * 2021-08-02 2023-02-09 주식회사 바이오뱅크힐링 블라우티아 속 균주, 류코노스톡 속 균주 또는 루미노코쿠스 속 균주 및 그의 유래의 소포체 및 그의 항염증 및 항균 용도
AU2023225121A1 (en) * 2022-02-23 2024-07-18 Société des Produits Nestlé S.A. Compositions and methods for reducing the occurrence of diarrhea by promoting blautia obeum in the gut microbiota

Family Cites Families (366)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
JPS5031249B1 (lt) 1970-12-17 1975-10-08
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
JPS5710876B2 (lt) 1974-04-08 1982-03-01
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
NL8300698A (nl) 1983-02-24 1984-09-17 Univ Leiden Werkwijze voor het inbouwen van vreemd dna in het genoom van tweezaadlobbige planten; agrobacterium tumefaciens bacterien en werkwijze voor het produceren daarvan; planten en plantecellen met gewijzigde genetische eigenschappen; werkwijze voor het bereiden van chemische en/of farmaceutische produkten.
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
DK122686D0 (da) 1986-03-17 1986-03-17 Novo Industri As Fremstilling af proteiner
FR2613624B1 (fr) 1987-04-10 1990-11-23 Roussy Inst Gustave Composition pharmaceutique, administrable par voie orale, destinee a reduire les effets des b-lactamines
DE68928665T2 (de) 1988-08-02 1998-11-12 Gastro Services Pty Ltd Behandlung von gastro-intestinalen krankheiten
US5443826A (en) 1988-08-02 1995-08-22 Borody; Thomas J. Treatment of gastro-intestinal disorders with a fecal composition or a composition of bacteroides and E. Coli
KR100225087B1 (ko) 1990-03-23 1999-10-15 한스 발터라벤 피타아제의 식물내 발현
AU639570B2 (en) 1990-05-09 1993-07-29 Novozymes A/S A cellulase preparation comprising an endoglucanase enzyme
GB9107305D0 (en) 1991-04-08 1991-05-22 Unilever Plc Probiotic
US5443951A (en) 1992-07-20 1995-08-22 Kabushiki Kaisha Yakult Honsha Species-specific oligonucleotides for bifidobacteria and a method of detection using the same
JPH08504327A (ja) 1992-12-10 1996-05-14 ギスト ブロカデス ナムローゼ フェンノートシャップ 糸状菌における異種タンパクの生産
US5741665A (en) 1994-05-10 1998-04-21 University Of Hawaii Light-regulated promoters for production of heterologous proteins in filamentous fungi
US5599795A (en) 1994-08-19 1997-02-04 Mccann; Michael Method for treatment of idiopathic inflammatory bowel disease (IIBD)
AUPM823094A0 (en) 1994-09-16 1994-10-13 Goodman Fielder Limited Probiotic compositions
AUPM864894A0 (en) 1994-10-07 1994-11-03 Borody, Thomas Julius Treatment of bowel-dependent neurological disorders
RU2078815C1 (ru) 1995-01-17 1997-05-10 Московский научно-исследовательский институт эпидемиологии и микробиологии им.Г.Н.Габричевского Штамм бактерий bifidobacterium breve, используемый для получения бактерийных лечебно-профилактических бифидосодержащих препаратов
JPH08259450A (ja) 1995-03-17 1996-10-08 Nichinichi Seiyaku Kk インターフェロン産生増強剤
US6861053B1 (en) 1999-08-11 2005-03-01 Cedars-Sinai Medical Center Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
AUPN698495A0 (en) 1995-12-06 1996-01-04 Pharma Pacific Pty Ltd Improved therapeutic formulation and method
SE508045C2 (sv) 1996-02-26 1998-08-17 Arla Ekonomisk Foerening Adhesionsinhibitorer, preparat innehållande desamma och förfarande för framställning därav
ATE407700T1 (de) 1996-03-20 2008-09-15 Univ New South Wales Veränderung der mikrobenflora im verdauungstrakt
AUPN881396A0 (en) 1996-03-20 1996-04-18 Arnott's Biscuits Limited Enhancement of microbial colonization of the gastrointestinal tract
DK0894126T3 (da) 1996-03-27 2006-06-12 Novozymes As Alkalisk phosphatase-deficient trådformet svamp
US6033864A (en) 1996-04-12 2000-03-07 The Regents Of The University Of California Diagnosis, prevention and treatment of ulcerative colitis, and clinical subtypes thereof, using microbial UC pANCA antigens
WO1998043081A1 (en) 1997-03-26 1998-10-01 Ligand Pharmaceuticals Incorporated Treatment of gastrointestinal disease with ppar modulators
SE511524C2 (sv) 1997-06-02 1999-10-11 Essum Ab Lactobacillus casei rhamnosus-stam samt farmaceutisk beredning för bekämpning av patogena tarmbakterier
US5925657A (en) 1997-06-18 1999-07-20 The General Hospital Corporation Use of PPARγ agonists for inhibition of inflammatory cytokine production
AUPO758297A0 (en) 1997-06-27 1997-07-24 Rowe, James Baber Control of acidic gut syndrome
US5951977A (en) 1997-10-14 1999-09-14 The United States Of America, As Represented By The Secretary Of Agriculture Competitive exclusion culture for swine
IT1298918B1 (it) 1998-02-20 2000-02-07 Mendes Srl Uso di batteri dotati di arginina deiminasi per indurre apoptosi e/o ridurre una reazione infiammatoria e composizioni farmaceutiche
DE19826928A1 (de) 1998-06-17 1999-12-23 Novartis Consumer Health Gmbh Arzneimittel, lebensfähige anaerobe Bakterien enthaltend, die die Sulfatreduktion sulfatreduzierender Bakterien hemmen
ID29150A (id) 1999-01-15 2001-08-02 Entpr Ireland Cs Penggunaan lactobacillus salivarius
US7090973B1 (en) 1999-04-09 2006-08-15 Oscient Pharmaceuticals Corporation Nucleic acid sequences relating to Bacteroides fragilis for diagnostics and therapeutics
ES2204684T3 (es) 1999-08-27 2004-05-01 Eli Lilly And Company Derivados de biaril-oxa(tia)zol y su uso como modulares de ppar.
ATE311762T1 (de) 2000-02-08 2005-12-15 Dsm Ip Assets Bv Verwendung von säurestabilen subtilisinproteasen in tierfutter
FR2808689B1 (fr) * 2000-05-11 2004-09-03 Agronomique Inst Nat Rech Utilisation de souches acetogenes hydrogenotrophes pour la prevention ou le traitement de troubles digestifs
US20020013270A1 (en) 2000-06-05 2002-01-31 Bolte Ellen R. Method for treating a mental disorder
AUPQ899700A0 (en) 2000-07-25 2000-08-17 Borody, Thomas Julius Probiotic recolonisation therapy
JP2004536557A (ja) 2000-11-27 2004-12-09 ワシントン・ユニバーシティ 哺乳動物の腸に対する共生ミクロフローラの効果を調べるための方法およびそれに基づく胃腸関連疾患の治療
DE10101793A1 (de) 2001-01-17 2002-08-01 Manfred Nilius Verwendung von SLPI zur Behandlung chronisch-entzündlicher Darmerkrankungen
EP1227152A1 (en) 2001-01-30 2002-07-31 Société des Produits Nestlé S.A. Bacterial strain and genome of bifidobacterium
KR100437497B1 (ko) 2001-03-07 2004-06-25 주식회사 프로바이오닉 로타바이러스 및 유해 미생물 억제 활성을 가지는 신규내산성 락토바실러스 루테리 프로바이오-16 및 이를함유하는 생균활성제
EP1243273A1 (en) 2001-03-22 2002-09-25 Societe Des Produits Nestle S.A. Composition comprising a prebiotic for decreasing infammatory process and abnormal activation of non-specific immune parameters
ATE463505T1 (de) 2001-04-20 2010-04-15 Inst Systems Biology Toll-ähnlichen-rezeptor-5-liganden und verwendungsverfahren
EP1260227A1 (en) 2001-05-23 2002-11-27 Societe Des Produits Nestle S.A. Lipoteichoic acid from lactic acid bacteria and its use to modulate immune responses mediated by gram-negative bacteria, potential pathogenic gram-positive bacteria
US20030092163A1 (en) 2001-07-26 2003-05-15 Collins John Kevin Probiotic bifidobacterium strains
MXPA04001999A (es) 2001-09-05 2004-07-16 Vsl Pharmaceuticals Inc Bacterias de acido lactico que comprende dinucleotidos de citosina-guanina no metilados para usarse en terapia.
GB0127916D0 (en) 2001-11-21 2002-01-16 Rowett Res Inst Method
WO2003045317A2 (en) 2001-11-27 2003-06-05 Washington University Therapeutic protein and treatments
DK2224012T3 (da) 2001-12-17 2013-05-13 Corixa Corp Sammensætninger og fremgangsmåder til terapi og diagnose af inflammatoriske tarmsygdomme
US7101565B2 (en) 2002-02-05 2006-09-05 Corpak Medsystems, Inc. Probiotic/prebiotic composition and delivery method
DE10206995B4 (de) 2002-02-19 2014-01-02 Orthomol Pharmazeutische Vertriebs Gmbh Mikronährstoffkombinationsprodukt mit Pro- und Prebiotika
JP2003261453A (ja) 2002-03-11 2003-09-16 Nippon Berumu Kk E.フェカリスからなる抗腫瘍剤及び放射線防護剤
NZ537706A (en) 2002-06-28 2008-03-28 Puleva Biotech Sa Probiotic microbial strains, comprising non-pathogenic strains which are capable of surviving in and being transferred to breast milk and/or amniotic fluid after oral intake in healthy individuals without colonizing other internal organs except mucousas
US20040005304A1 (en) 2002-07-08 2004-01-08 Mak Wood, Inc. Novel compositions and methods for treating neurological disorders and associated gastrointestinal conditions
GB0307026D0 (en) 2003-03-27 2003-04-30 Rowett Res Inst Bacterial supplement
EP1481681A1 (en) 2003-05-30 2004-12-01 Claudio De Simone Lactic acid bacteria combination and compositions thereof
GB0316915D0 (en) 2003-07-18 2003-08-20 Glaxo Group Ltd Compounds
WO2005007834A1 (en) 2003-07-23 2005-01-27 Probionic Corp. Acid tolerant probiotic lactobacillus plantarum probio-38 that can suppress the growth of pathogenic microorganism and tge coronavirus
US7485325B2 (en) 2003-08-06 2009-02-03 Gayle Dorothy Swain Animal food supplement compositions and methods of use
JP4683881B2 (ja) 2003-08-27 2011-05-18 有限会社アーク技研 抗腫瘍活性剤
US8192733B2 (en) 2003-08-29 2012-06-05 Cobb & Associates Probiotic composition useful for dietary augmentation and/or combating disease states and adverse physiological conditions
US20050163764A1 (en) 2003-09-22 2005-07-28 Yale University Treatment with agonists of toll-like receptors
GB0323039D0 (en) 2003-10-01 2003-11-05 Danisco Method
DK1675481T3 (da) 2003-10-24 2009-01-19 Nutricia Nv Synbiotisk præparat til börn
US20050239706A1 (en) 2003-10-31 2005-10-27 Washington University In St. Louis Modulation of fiaf and the gastrointestinal microbiota as a means to control energy storage in a subject
JP4850715B2 (ja) 2003-12-17 2012-01-11 エヌ.ブイ.・ヌートリシア 乳酸産生菌及び肺機能
ES2235642B2 (es) 2003-12-18 2006-03-01 Gat Formulation Gmbh Proceso de multi-microencapsulacion continuo para la mejora de la estabilidad y almacenamiento de ingredientes biologicamente activos.
AU2005227320B2 (en) 2004-03-22 2010-06-24 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, National Insitutes Of Health Cellular and viral inactivation
WO2005107381A2 (en) 2004-05-07 2005-11-17 Hans-Gustaf Ljunggren Use of flagellin as an adjuvant for vaccine
US7638513B2 (en) 2004-06-02 2009-12-29 Schering Corporation Compounds for the treatment of inflammatory disorders
PE20060426A1 (es) 2004-06-02 2006-06-28 Schering Corp DERIVADOS DE ACIDO TARTARICO COMO INHIBIDORES DE MMPs, ADAMs, TACE Y TNF-alfa
AU2005251397B2 (en) 2004-06-07 2010-11-11 Qu Biologics Inc. Bacterial compositions for the treatment of cancer
DE602004006258T3 (de) 2004-08-24 2013-08-29 Nutricia N.V. Nahrungszusammensetzung die unverdauliche Transgalaktooligosaccharide sowie verdauliche Galaktose-Saccharide enthält
US20060062774A1 (en) 2004-09-21 2006-03-23 The Procter & Gamble Company Compositions for maintaining and restoring normal urogenital flora
KR100468522B1 (ko) 2004-10-12 2005-01-31 주식회사 프로바이오닉 코로나바이러스와 돼지 써코바이러스 2형의 생육을 억제하는 신규한 내산성 프로바이오틱 엔테로코커스훼시움 프로바이오-63
US20060115465A1 (en) 2004-10-29 2006-06-01 Macfarlane George Treatment of gastrointestinal disorders
ITMI20042189A1 (it) 2004-11-16 2005-02-16 Anidral Srl Composizione a base di batteri probiotici e suo uso nella prevenzione e-o nel trattamento di patologie e-o infezioni respiratorie e nel miglioramento della funzionalita' intestinale
ATE526836T1 (de) 2005-02-28 2011-10-15 Nutricia Nv Nährstoffzusammensetzung mit probiotika
US20100048595A1 (en) 2005-03-23 2010-02-25 Washington University In St. Louis Use of archaea to modulate the nutrient harvesting functions of the gastrointestinal microbiota
US20090233888A1 (en) 2005-03-23 2009-09-17 Usc Stevens, University Of Southern California Treatment of disease conditions through modulation of hydrogen sulfide produced by small intestinal bacterial overgrowth
JP2006265212A (ja) 2005-03-25 2006-10-05 Institute Of Physical & Chemical Research Il−21産生誘導剤
US20100233312A9 (en) 2005-04-11 2010-09-16 The Procter & Gamble Company Compositions comprising probiotic and sweetener components
EP1714660A1 (en) 2005-04-21 2006-10-25 N.V. Nutricia Uronic acid and probiotics
PL1874917T3 (pl) 2005-04-26 2012-07-31 Teagasc The Agriculture And Food Dev Authority Kompozycja probiotyczna odpowiednia dla zwierząt
EP2439273B1 (en) 2005-05-09 2019-02-27 Ono Pharmaceutical Co., Ltd. Human monoclonal antibodies to programmed death 1(PD-1) and methods for treating cancer using anti-PD-1 antibodies alone or in combination with other immunotherapeutics
US7572474B2 (en) 2005-06-01 2009-08-11 Mead Johnson Nutrition Company Method for simulating the functional attributes of human milk oligosaccharides in formula-fed infants
US8075934B2 (en) 2008-10-24 2011-12-13 Mead Johnson Nutrition Company Nutritional composition with improved digestibility
JP2007084533A (ja) 2005-08-24 2007-04-05 Prima Meat Packers Ltd 免疫応答調節組成物及び該組成物を有効成分とする食品
US7625704B2 (en) 2005-08-31 2009-12-01 Fred Hutchinson Cancer Research Center Methods and compositions for identifying bacteria associated with bacteria vaginosis
ATE445415T1 (de) 2005-09-01 2009-10-15 Schering Corp Verwendung von il-23 und il-17-antagonisten zur behandlung von autoimmuner entzündlicher augenerkrankung
US20090028840A1 (en) 2005-09-23 2009-01-29 Gwangju Institute Of Sciecne And Technology Compositions For Preventing Or Treating Arthritis Comprising Lactic Acid Bacteria and Collangen As Active Ingredients
EP1776877A1 (en) 2005-10-21 2007-04-25 N.V. Nutricia Method for stimulating the intestinal flora
MY144556A (en) 2005-10-24 2011-09-30 Nestec Sa Dietary fiber formulation and method of administration
JP2007116991A (ja) 2005-10-28 2007-05-17 Eternal Light General Institute Inc 機能性食品
US7767420B2 (en) 2005-11-03 2010-08-03 Momenta Pharmaceuticals, Inc. Heparan sulfate glycosaminoglycan lyase and uses thereof
CN101365677A (zh) 2005-12-01 2009-02-11 先灵公司 治疗炎性病症和微生物疾病的化合物
WO2007098371A2 (en) 2006-02-16 2007-08-30 Wayne State University Use of flagellin to prevent and treat gram negative bacterial infection
US20080260906A1 (en) 2006-03-17 2008-10-23 Marko Stojanovic Compositions comprising probiotic and sweetener components
JP5031249B2 (ja) 2006-03-22 2012-09-19 学校法人北里研究所 炎症抑制作用のある菌体含有組成物
WO2007136719A2 (en) 2006-05-18 2007-11-29 Biobalance Llc Biotherapeutic compositions comprising probiotic escherichia coli and uses thereof
AU2007267560B2 (en) 2006-05-26 2010-10-21 Nestec S.A. Methods of use and nutritional compositions of Touchi Extract
EP2046352A4 (en) 2006-06-06 2012-03-21 Univ Mcgill FERMENTED MILK PRODUCT AND ITS USE
TW200819540A (en) 2006-07-11 2008-05-01 Genelux Corp Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders
EP2845496A1 (en) 2006-08-04 2015-03-11 SHS International Ltd. Protein free formula with prebiotics
WO2008031438A2 (en) 2006-09-13 2008-03-20 Region Hovedstaden V/Gentofte Hospital Treatment of asthma, eczema and/or allergy using non-pathogenic organisms
US20080069861A1 (en) 2006-09-19 2008-03-20 National Starch And Chemical Investment Holding Corporation Probiotic/Non-Probiotic Combinations
CA2667167C (en) 2006-10-27 2014-02-18 Pfizer Products Inc. Hydroxypropyl methyl cellulose hard capsules and process of manufacture
WO2008053444A2 (en) 2006-11-01 2008-05-08 The Procter & Gamble Company Treating a respiratory condition with bifidobacterium
EP1920781B1 (en) 2006-11-10 2015-03-04 Glycotope GmbH Compositions comprising a core-1 positive microorganism and their use for the treatment or prophylaxis of tumors
WO2008064489A1 (en) 2006-12-01 2008-06-05 Mcmaster University Probiotics to inhibit inflammation
EP2102350A4 (en) 2006-12-18 2012-08-08 Univ St Louis INTESTINAL MICROBIOMA AS A BIOMARKER AND THERAPEUTIC TARGET FOR TREATING OBESITY OR OBESITY-RELATED DISORDER
DE102006062250A1 (de) * 2006-12-22 2008-06-26 Roland Saur-Brosch Verwendung einer Zusammensetzung aus Mineralstoffen und/oder Vitaminen und gegebenenfalls acetogenen und/oder butyrogenen Bakterien zur oralen oder rektalen Verabreichung für die Behandlung und Vorbeugung von abdominalen Beschwerden
WO2008083157A2 (en) 2006-12-29 2008-07-10 Washington University In St. Louis Altering pgc-1alapha, ampk, fiaf, or the gastrointestinal microbiota as a means to modulate body fat and/or weight loss in a subject
JP2008195635A (ja) 2007-02-09 2008-08-28 Crossfield Bio Inc 馬用乳酸菌製剤
WO2008106373A1 (en) 2007-02-28 2008-09-04 Mead Johnson Nutrition Company Product containing inactivated probiotic for children or infants
AU2008231466B2 (en) 2007-03-28 2013-05-23 Alimentary Health Limited Probiotic Bifidobacterium strains
WO2008117267A2 (en) 2007-03-28 2008-10-02 Alimentary Health Limited Probiotic bifidobacterium strains
US20080299098A1 (en) 2007-04-24 2008-12-04 Chea-Yun Se Broad-Spectrum Antibacterial and Antifungal Activity of Lactobacillus Johnsonii D115
EP1997499A1 (en) 2007-05-31 2008-12-03 Puleva Biotech, S.A. Mammalian milk microorganisms, compositions containing them and their use for the treatment of mastitis
EP1997906A1 (en) 2007-06-01 2008-12-03 Friesland Brands B.V. Lactobacillus
EP1997907A1 (en) 2007-06-01 2008-12-03 Friesland Brands B.V. Bifidobacteria
EP1997905A1 (en) 2007-06-01 2008-12-03 Friesland Brands B.V. Nucleic acid amplification
WO2008153377A1 (en) 2007-06-15 2008-12-18 N.V. Nutricia Nutrition with non-viable bifidobacterium and non-digestible oligosaccharide
EP2522358B1 (en) 2007-06-27 2016-11-09 Laboratorios Ordesa, S.l. Peptides against rotavirus infection
HUP0700552A2 (en) 2007-08-27 2009-03-30 Janos Dr Feher Method and composition inhibiting inflammation
WO2009030254A1 (en) 2007-09-04 2009-03-12 Curevac Gmbh Complexes of rna and cationic peptides for transfection and for immunostimulation
US20100284979A1 (en) 2007-10-01 2010-11-11 University College Cork, National University Of Ireland, Cork Modulation of Tissue Fatty Acid Composition of a Host by Human Gut Bacteria
JP5327984B2 (ja) 2007-10-20 2013-10-30 ユニベルシテ・ド・リエージュ ビフィズス菌の種
WO2009055362A1 (en) 2007-10-26 2009-04-30 Moore Brenda E Probiotic compositions and methods for inducing and supporting weight loss
EP2205642B1 (en) 2007-11-02 2016-01-27 Momenta Pharmaceuticals, Inc. Non-anticoagulant polysaccharide compositions
EP2065048A1 (en) 2007-11-30 2009-06-03 Institut Pasteur Use of a L. casei strain, for the preparation of a composition for inhibiting mast cell activation
EP2356992B1 (en) 2007-12-07 2017-08-16 N.V. Nutricia Bifidobactrium for dust mite allergy
US20100330190A1 (en) 2007-12-17 2010-12-30 Compans Richard W Immunogenic compositions and methods of use thereof
ES2343499B1 (es) 2007-12-24 2011-06-10 Consejo Superior De Investigaciones Cientificas Microorganismos para mejorar el estado de salud de individuos con desordenes relacionados con la ingesta de gluten.
MX2010008720A (es) 2008-02-06 2010-08-30 Procter & Gamble Composiciones, metodos y estuches para mejorar la respuesta inmunitaria a una enfermedad respiratoria.
EP2103226A1 (en) 2008-03-18 2009-09-23 Friesland Brands B.V. Long-life probiotic food product
AU2009236585B2 (en) 2008-04-18 2013-03-07 Vaxinnate Corporation Deletion mutants of flagellin and methods of use
WO2009138220A1 (en) 2008-05-13 2009-11-19 Glycotope Gmbh Fermentation process
MX2008006546A (es) 2008-05-21 2009-11-23 Sigma Alimentos Sa De Cv Bifidobacteria productora de ácido fólico, composición alimenticia y uso de la bifidobacteria.
CN102940652B (zh) 2008-05-28 2015-03-25 青岛东海药业有限公司 两形真杆菌制剂及其应用
CN101590081A (zh) 2008-05-28 2009-12-02 青岛东海药业有限公司 凸腹真杆菌和两形真杆菌制剂及其应用
US8586029B2 (en) 2008-06-04 2013-11-19 Trustees Of Dartmouth College Prevention or treatment of immune-relevant disease by modification of microfloral populations
EP2133088A3 (en) 2008-06-09 2010-01-27 Nestec S.A. Rooibos and inflammation
WO2009151315A1 (en) 2008-06-13 2009-12-17 N.V. Nutricia Nutritional composition for infants delivered via caesarean section
WO2009154463A2 (en) 2008-06-20 2009-12-23 Stichting Top Institute Food And Nutrition Butyrate as a medicament to improve visceral perception in humans
EP2138186A1 (en) 2008-06-24 2009-12-30 Nestec S.A. Probiotics, secretory IgA and inflammation
WO2010002241A1 (en) 2008-06-30 2010-01-07 N.V. Nutricia Nutritional composition for infants delivered via caesarean section
JP2010034283A (ja) 2008-07-29 2010-02-12 Hitachi Kokusai Electric Inc 基板処理装置
KR101017448B1 (ko) 2008-09-18 2011-02-23 주식회사한국야쿠르트 대장의 건강 증진 효능을 갖는 비피도박테리움 롱검 에이취와이8004 및 이를 유효성분으로 함유하는 제품
US8137718B2 (en) 2008-09-19 2012-03-20 Mead Johnson Nutrition Company Probiotic infant products
US20100074870A1 (en) 2008-09-19 2010-03-25 Bristol-Myers Squibb Company Probiotic infant products
KR101057357B1 (ko) 2008-09-22 2011-08-17 광주과학기술원 유산균 및 콜라겐을 유효성분으로 포함하는 관절염 예방 또는 치료용 약제학적 조성물 및 식품 조성물
US9603876B2 (en) 2008-09-25 2017-03-28 New York University Compositions and methods for restoring gastrointestinal microbiota following antibiotic treatment
WO2010037408A1 (en) 2008-09-30 2010-04-08 Curevac Gmbh Composition comprising a complexed (m)rna and a naked mrna for providing or enhancing an immunostimulatory response in a mammal and uses thereof
WO2010037402A1 (en) 2008-10-02 2010-04-08 Dako Denmark A/S Molecular vaccines for infectious disease
EP2373182A1 (en) 2008-12-05 2011-10-12 Nestec S.A. Compositions for use in low-birth weight infants
CA2746805A1 (en) 2008-12-19 2010-06-24 Nestec S.A. Prevention and treatment of rotavirus diarrhoea
IT1392672B1 (it) 2009-01-12 2012-03-16 Wyeth Consumer Healthcare S P A Composizioni comprendenti componenti probiotici e prebiotici e sali minerali, con lactoferrina
GB0903016D0 (en) * 2009-02-23 2009-04-08 Univ Gent Method for alleviating intestinal problems and novel bacterial strains therefor
PE20160653A1 (es) 2009-03-05 2016-07-24 Abbvie Inc Proteinas de union a il-17
JP5710876B2 (ja) 2009-03-26 2015-04-30 クロスフィールドバイオ株式会社 新規ビフィドバクテリウム属微生物およびその利用
EP2427499A1 (en) 2009-05-07 2012-03-14 Tate&Lyle Ingredients France SAS Compositions and methods for making alpha-(1,2)-branched alpha-(1,6) oligodextrans
EP2251020A1 (en) 2009-05-11 2010-11-17 Nestec S.A. Short-time high temperature treatment generates microbial preparations with anti-inflammatory profiles
EP2429538B1 (en) 2009-05-11 2015-10-21 Nestec S.A. Non-replicating bifidobacterium longum ncc2705 and immune disorders
EP2251022A1 (en) 2009-05-11 2010-11-17 Nestec S.A. Non-replicating micro-organisms and their immune boosting effect
KR20100128168A (ko) 2009-05-27 2010-12-07 중앙대학교 산학협력단 공액 리놀레산 생산능이 우수한 신규한 균주
US20100311686A1 (en) 2009-06-03 2010-12-09 Kasper Lloyd H Nutraceutical composition and methods for preventing or treating multiple sclerosis
WO2010143940A1 (en) 2009-06-12 2010-12-16 N.V. Nutricia Synergistic mixture of beta-galacto-oligosaccharides with beta-1,3 and beta-1,4/1,6 linkages
EP2443259A4 (en) 2009-06-16 2012-10-10 Univ Columbia BIOMARKERS FOR AUTISM AND USES THEREOF
WO2011005756A1 (en) 2009-07-06 2011-01-13 Puretech Ventures, Llc Delivery of agents targeted to microbiota niches
AU2010274941A1 (en) 2009-07-24 2012-02-09 Southwest Regional Pcr, Llc Universal microbial diagnosis, detection, quantification, and specimen-targeted therapy
WO2011020748A1 (en) 2009-08-18 2011-02-24 Nestec S.A. A nutritional composition comprising bifidobacterium longum strains and reducing food allergy symptoms, especially in infants and children
US20110053829A1 (en) 2009-09-03 2011-03-03 Curevac Gmbh Disulfide-linked polyethyleneglycol/peptide conjugates for the transfection of nucleic acids
EP2480255B1 (en) 2009-09-23 2017-11-22 Thomas Julius Borody Therapy for chronic enteric infections
EP2308498A1 (en) 2009-09-30 2011-04-13 Nestec S.A. Administration of Bifidobacterium breve during infancy to prevent inflammation later in life
EP2486143A1 (en) 2009-10-05 2012-08-15 AAK Patent B.V. Methods for diagnosing irritable bowel syndrome
EP2485742A4 (en) 2009-10-06 2013-03-20 Scott Dorfner ANTIBIOTIC FORMULATIONS WITH REDUCED SIDE EFFECTS ON STOMACH AND DARM
ES2595444T3 (es) 2009-11-11 2016-12-30 Alimentary Health Limited Cepa de Bifidobacterium probiótica
WO2011075138A1 (en) 2009-12-18 2011-06-23 Hill's Pet Nutrition, Inc. Pet food compositions including probiotics and methods of manufacture and use thereof
US20150104418A1 (en) 2014-12-18 2015-04-16 Microbios, Inc. Bacterial composition
FR2955774A1 (fr) 2010-02-02 2011-08-05 Aragan Preparation destinee a traiter l'exces ponderal et les desordres associes et applications de ladite preparation
NL2004201C2 (en) 2010-02-05 2011-08-08 Friesland Brands Bv Use of sialyl oligosaccharides to modulate the immune system.
NL2004200C2 (en) 2010-02-05 2011-08-08 Friesland Brands Bv Use of sialyl oligosaccharides in weight management.
IT1398553B1 (it) 2010-03-08 2013-03-01 Probiotical Spa Composizione comprendente batteri probiotici per il trattamento di patologie associate con le alterazioni del sistema immunitario.
JP5737646B2 (ja) 2010-03-24 2015-06-17 森下仁丹株式会社 抗アレルギー剤
WO2011121379A1 (en) 2010-03-30 2011-10-06 Assistance Publique - Hopitaux De Paris Use of bifidobacteria for preventing allergy in breastfed infants
US8951512B2 (en) 2010-05-04 2015-02-10 New York University Methods for treating bone disorders by characterizing and restoring mammalian bacterial microbiota
WO2011149335A1 (en) 2010-05-25 2011-12-01 N.V. Nutricia Immune imprinting nutritional composition
US20130195802A1 (en) 2010-06-01 2013-08-01 Moore Research Enterprises Llc Cellular Constituents From Bacteroides, Compositions Thereof, and Therapeutic Methods Employing Bacteroides or Cellular Constituents Thereof
WO2011151941A1 (ja) 2010-06-04 2011-12-08 国立大学法人東京大学 制御性t細胞の増殖または集積を誘導する作用を有する組成物
TWI417054B (zh) 2010-06-15 2013-12-01 Jen Shine Biotechnology Co Ltd 新穎糞腸球菌ljs-01及其益生用途
EP2397145A1 (en) 2010-06-18 2011-12-21 Nestec S.A. L. johnsonii La1, B. longum NCC2705 and immune disorders
FR2962045B1 (fr) 2010-07-05 2012-08-17 Bifinove Complexe macromoleculaire d'origine bacterienne et utilisation dudit complexe moleculaire pour prevenir et traiter les rhumatismes inflammatoires
TWI401086B (zh) 2010-07-20 2013-07-11 Univ China Medical 胚芽乳酸桿菌及其用途
SG187201A1 (en) 2010-07-26 2013-02-28 Qu Biolog Inc Immunogenic anti-inflammatory compositions
EP3311825A1 (en) 2010-08-04 2018-04-25 Thomas Julius Borody Compositions for fecal floral transplantation and methods for making and using them
WO2012024638A2 (en) 2010-08-20 2012-02-23 New York University Compositions and methods for treating obesity and related disorders by characterizing and restoring mammalian bacterial microbiota
KR101250463B1 (ko) 2010-10-12 2013-04-15 대한민국 신생아 분변에서 분리한 내산소성 비피도박테리움 롱검 비피더스 유산균 및 이를 이용한 프로바이오틱 조성물
JP2013544507A (ja) 2010-10-27 2013-12-19 カンティバクト・アクティーゼルスカブ インターカレータ分子を含むプローブによる標的dna及びrnaの捕捉
CN102031235B (zh) 2010-11-09 2012-07-25 中国农业大学 一种粪肠球菌anse228及其应用
EP2455092A1 (en) 2010-11-11 2012-05-23 Nestec S.A. Non-replicating probiotic micro-organisms protect against upper respiratory tract infections
US20120128644A1 (en) 2010-11-24 2012-05-24 Oragenics, Inc. Use of Bacteria to Treat and Prevent Respiratory Infections
CN102093967B (zh) 2010-12-02 2013-01-30 中国农业科学院特产研究所 一株水貂源屎肠球菌及其应用
ES2389547B1 (es) 2010-12-07 2013-08-08 Consejo Superior De Investigaciones Científicas (Csic) Bifidobacterium cect 7765 y su uso en la prevención y/o tratamiento del sobrepeso, la obesidad y patologías asociadas.
WO2012097012A1 (en) 2011-01-10 2012-07-19 Cleveland Biolabs, Inc. Use of toll-like receptor agonist for treating cancer
EP2481299B1 (en) 2011-01-31 2016-12-07 Dr. Fischer Gesundheitsprodukte GmbH Bifidobacterium bifidum strains for application in gastrointestinal diseases
JP5840368B2 (ja) 2011-02-02 2016-01-06 カルピス株式会社 関節炎予防改善用物質
AP2013007097A0 (en) 2011-02-09 2013-09-30 Lavivo Ab Synbiotic compositions for restoration and reconstitution of gut microbiota
EP2683390B1 (en) 2011-03-09 2017-05-03 Regents Of The University Of Minnesota Compositions and methods for transplantation of colon microbiota
BRPI1100857A2 (pt) 2011-03-18 2013-05-21 Alexandre Eduardo Nowill agente imunomodulador e suas combinaÇÕes, seu uso e mÉtodo imunoterÁpico para a recontextualizaÇço, reprogramaÇço e reconduÇço do sistema imune em tempo real
WO2012140636A1 (en) 2011-04-11 2012-10-18 Alimentary Health Limited A probiotic formulation
WO2012142605A1 (en) * 2011-04-15 2012-10-18 Samaritan Health Services Rapid recolonization deployment agent
JP2014512388A (ja) 2011-04-20 2014-05-22 マイコ・バイオ,インコーポレーテッド 免疫反応を増進するための組成物および方法
EP2707379A4 (en) 2011-05-13 2014-10-08 Glycosyn LLC USE OF PURIFIED 2'-FUCOSYLLACTOSIS, 3-FUCOSYLLACTOSIS AND LACTODIFUCOTETRAOSE AS PREBIOTICS
KR20120133133A (ko) 2011-05-30 2012-12-10 한국 한의학 연구원 생약 추출물 또는 이의 유산균 발효물을 포함하는 호흡기 질환의 예방 또는 치료용 조성물
WO2012170478A2 (en) 2011-06-06 2012-12-13 The University Of North Carolina At Chapel Hill Methods and kits for detecting adenomas, colorectal cancer, and uses thereof
GB201110095D0 (en) 2011-06-15 2011-07-27 Danisco Method of treatment
JP2013005759A (ja) 2011-06-24 2013-01-10 Kyodo Milk Industry Co Ltd マウス腸内菌叢の推測方法
JP6222626B2 (ja) 2011-07-07 2017-11-01 長岡香料株式会社 フルクトース吸収阻害剤
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
WO2013008102A2 (en) 2011-07-14 2013-01-17 R.E.D. Laboratories N.V../ S.A. Methods and compositions for evaluating and/or treating chronic immune diseases
US20130022575A1 (en) 2011-07-19 2013-01-24 Microbial Rx Systems and methods of replacing intestinal flora
TWI417045B (zh) 2011-08-05 2013-12-01 Aerolead Internat Ltd Pharmacodynamic Test Method for Water - borne Smoke
CN102304483A (zh) 2011-08-12 2012-01-04 北京金泰得生物科技股份有限公司 一株饲用屎肠球菌及其应用
KR101261872B1 (ko) 2011-08-23 2013-05-14 대한민국 (식품의약품안전처장) 장내 미생물 효소복합체 및 이의 제조방법
CA2848762C (en) * 2011-09-14 2021-07-27 Queen's University At Kingston Method for treatment of disorders of the gastrointestinal system
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
KR20140082964A (ko) 2011-10-11 2014-07-03 아힘 바이오테라퓨틱스 에이비 혐기성 조건으로 배양된 인간 장내 미생물을 포함하는 조성물
CN103082292B (zh) 2011-11-02 2015-03-04 深圳华大基因研究院 罗斯氏菌(Roseburia)在治疗和预防肥胖相关疾病中的应用
CN102373172B (zh) 2011-11-03 2013-03-20 北京龙科方舟生物工程技术有限公司 一株屎肠球菌及其应用
US10238694B2 (en) 2011-12-01 2019-03-26 The University Of Tokyo Human-derived bacteria that induce proliferation or accumulation of regulatory T cells
ES2408279B1 (es) 2011-12-15 2014-09-09 Universidad De Las Palmas De Gran Canaria Bacteria acido láctica probiótica
ITBG20120010A1 (it) 2012-02-24 2013-08-25 Milano Politecnico Dispositivo per l'addestramento chirurgico
ITMI20120471A1 (it) 2012-03-26 2013-09-27 Giovanni Mogna Composizione a base di ceppi di batteri bifidobacterium longum in grado di aiutare il prolungamento della vita
JP5792105B2 (ja) 2012-03-27 2015-10-07 森永乳業株式会社 ラクト−n−ビオースiの製造方法
JP6201982B2 (ja) 2012-03-30 2017-09-27 味の素株式会社 糖尿病誘起細菌
US20130280724A1 (en) 2012-04-11 2013-10-24 Nestec Sa Methods for diagnosing impending diarrhea
JP2015512936A (ja) 2012-04-13 2015-04-30 トラスティーズ オブ ボストン カレッジ プレバイオティクス組成物およびその使用方法
GB201206599D0 (en) 2012-04-13 2012-05-30 Univ Manchester Probiotic bacteria
WO2013171515A1 (en) 2012-05-18 2013-11-21 Genome Research Limited Methods and groups
ES2436251B1 (es) 2012-05-25 2014-10-08 Consejo Superior De Investigaciones Científicas (Csic) Bacteroides cect 7771 y su uso en la prevención y tratamiento de sobrepeso, obesidad y alteraciones metabólicas e inmunológicas.
NZ703394A (en) 2012-06-04 2017-01-27 Centre For Digestive Diseases Compositions and methods for treating crohn’s disease and related conditions and infections
CN102743420A (zh) 2012-06-06 2012-10-24 上海交通大学 改善肠道菌群结构的方法及应用
US9676847B2 (en) 2012-06-25 2017-06-13 Orega Biotech IL-17 antagonist antibodies
AU2013298645B2 (en) 2012-07-31 2016-11-03 Société des Produits Nestlé S.A. Nutritional composition for promoting musculoskeletal health in patients with inflammatory bowel disease (IBD)
US20150211053A1 (en) 2012-08-01 2015-07-30 Bgi-Shenzhen Biomarkers for diabetes and usages thereof
WO2014032108A1 (en) 2012-08-29 2014-03-06 Borody Thomas J Laxative compositions and methods for treating constipation and related gastrointestinal diseases and conditions
JP6679309B2 (ja) 2012-08-29 2020-04-15 カリフォルニア インスティチュート オブ テクノロジー 自閉症スペクトラム障害の診断および処置
US9994809B2 (en) 2012-09-13 2018-06-12 Massachusetts Institute Of Technology Programmable drug delivery profiles of tumor-targeted bacteria
KR101473058B1 (ko) 2012-09-19 2014-12-16 주식회사 쎌바이오텍 과민성 대장 증후군 예방 또는 치료용 조성물
CN103652322B (zh) 2012-09-21 2016-02-10 临沂思科生物科技有限公司 一种含乳酸菌的复合益生菌饲料添加剂的制备方法
EP3401396A1 (en) 2012-10-03 2018-11-14 Metabogen AB Treating or preventing atherosclerosis or associated diseases by beta-carotene
FR2997091B1 (fr) 2012-10-22 2016-05-06 Fond Mediterranee Infection Utilisation d'un compose antioxydant pour la culture de bacteries sensibles a la tension en oxygene
US20150290140A1 (en) 2012-10-30 2015-10-15 Nestec S.A. Compositions comprising microparticles and probiotics to deliver a synergistic immune effect
WO2014070225A1 (en) 2012-10-30 2014-05-08 Deerland Enzymes, Inc. Prebiotic compositions comprising one or more types of bacteriophage
AU2013338774B2 (en) 2012-11-01 2017-03-02 Academisch Ziekenhuis Groningen Methods and compositions for stimulating beneficial bacteria in the gastrointestinal tract
WO2014075745A1 (en) 2012-11-19 2014-05-22 Université Catholique de Louvain Use of akkermansia for treating metabolic disorders
PT3628161T (pt) * 2012-11-23 2023-05-15 Seres Therapeutics Inc Composições bacterianas sinergísticas e métodos de produção e utilização das mesmas
US8906668B2 (en) 2012-11-23 2014-12-09 Seres Health, Inc. Synergistic bacterial compositions and methods of production and use thereof
CA2896795A1 (en) 2012-11-26 2014-05-30 Thomas Julius Borody Compositions for the restoration of a fecal microbiota and methods for making and using them
PL2931898T3 (pl) 2012-12-12 2016-09-30 Le Cong Projektowanie i optymalizacja systemów, sposoby i kompozycje do manipulacji sekwencją z domenami funkcjonalnymi
ES2786193T3 (es) 2012-12-12 2020-10-09 Broad Inst Inc Modificación por tecnología genética y optimización de sistemas, métodos y composiciones enzimáticas mejorados para la manipulación de secuencias
CN110872583A (zh) 2012-12-12 2020-03-10 布罗德研究所有限公司 用于序列操纵和治疗应用的系统、方法和组合物的递送、工程化和优化
US20140193464A1 (en) 2013-01-08 2014-07-10 Imagilin Technology, Llc Effects of probiotics on humans and animals under environmental or biological changes
US11185562B2 (en) 2013-02-04 2021-11-30 Seres Therapeutics, Inc. Compositions and methods for inhibition of pathogenic bacterial growth
EP2951283A4 (en) 2013-02-04 2017-01-25 Seres Therapeutics, Inc. Compositions and methods
AU2014219048B2 (en) 2013-02-22 2018-12-13 The Regents Of The University Of California Compositions and methods for promoting growth of beneficial microbes to treat or prevent disease or prolong life
BR112015020819A2 (pt) 2013-03-05 2017-07-18 Academisch Ziekenhuis Groningen uso de faecalibacterium prausnitzii htf-f (dsm 26943) para supressão de inflamação
EP2968187A4 (en) 2013-03-14 2016-08-17 Therabiome Llc TARGETED ADMINISTRATION OF PROBIOTIC ORGANISMS AND / OR THERAPEUTIC AGENTS IN THE GASTROINTESTINAL TRACT
US20160040215A1 (en) 2013-03-14 2016-02-11 Seres Therapeutics, Inc. Methods for Pathogen Detection and Enrichment from Materials and Compositions
WO2014150094A1 (en) 2013-03-15 2014-09-25 University Of Florida Research Foundation, Inc. Butyrogenic bacteria as probiotics to treat clostridium difficile
CA2902248A1 (en) 2013-03-15 2014-09-25 Microbiome Therapeutics, Llc Activated soy pod fiber
JP2016519664A (ja) 2013-03-15 2016-07-07 セレス セラピューティクス インコーポレイテッド ネットワークを基にした微生物組成物及び方法
CN103142656A (zh) 2013-03-18 2013-06-12 广州知光生物科技有限公司 脆弱拟杆菌在制备防治结肠癌组合物中的应用
CN103156888A (zh) 2013-03-18 2013-06-19 广州知光生物科技有限公司 脆弱拟杆菌在制备治疗炎症性肠病组合物中的应用
CN103146620A (zh) 2013-03-25 2013-06-12 广州知光生物科技有限公司 具有益生菌特性的脆弱拟杆菌
JP2014196260A (ja) 2013-03-29 2014-10-16 公立大学法人奈良県立医科大学 慢性閉塞性肺疾患の予防又は治療用組成物
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
JP2016521284A (ja) 2013-05-10 2016-07-21 カリフォルニア インスティチュート オブ テクノロジー 大腸ガンのプロバイオティクスによる防止および処置
US9511099B2 (en) 2013-06-05 2016-12-06 Rebiotix, Inc. Microbiota restoration therapy (MRT), compositions and methods of manufacture
WO2014197562A1 (en) 2013-06-05 2014-12-11 Rebiotix, Inc. Microbiota restoration therapy (mrt), compositions and methods of manufacture
WO2014201037A2 (en) 2013-06-10 2014-12-18 New York University Methods for manipulating immune responses by altering microbiota
WO2014200334A1 (en) 2013-06-14 2014-12-18 N.V. Nutricia Synbiotic composition for treatment of infections in allergic patients
WO2015003001A1 (en) 2013-07-01 2015-01-08 The Washington University Methods for identifying supplements that increase gut colonization by an isolated bacterial species, and compositions derived therefrom
WO2015003305A1 (zh) 2013-07-08 2015-01-15 吉瑞高新科技股份有限公司 电子烟盒
EP3019181A4 (en) 2013-07-09 2016-09-21 Puretech Ventures Llc COMPOSITIONS CONTAINING COMBINATIONS OF BIOACTIVE MICROFLORE DERIVED MOLECULES FOR THE TREATMENT OF DISEASE
CN105407728A (zh) 2013-07-21 2016-03-16 霍勒拜欧姆公司 用于微生物组表征、监测和治疗的方法和系统
US20160192689A1 (en) 2013-07-31 2016-07-07 Wikifoods, Inc. Encapsulated functional food compositions
EP3033091B1 (en) 2013-08-16 2022-09-07 Versitech Limited Probiotic composition and use thereof in the prevention and treatment of hepatocellular carcinoma
CN103509741B (zh) 2013-08-22 2015-02-18 河北农业大学 布劳特菌auh-jld56及其在牛蒡苷元转化中的应用
ITMI20131467A1 (it) 2013-09-06 2015-03-07 Sofar Spa Uso di una composizione comprendente microrganismi per aumentare la produzione intestinale di acido butirrico, di acido folico o di niacina e/o per diminuire la produzione intestinale di acido succinico
US10203329B2 (en) 2013-09-12 2019-02-12 The Johns Hopkins University Biofilm formation to define risk for colon cancer
ES2785330T3 (es) 2013-10-18 2020-10-06 Innovachildfood Ab Comida compuesta nutricionalmente equilibrada para lactantes y niños pequeños y método de producción de dicha comida
PL229020B1 (pl) 2013-11-13 2018-05-30 Inst Biotechnologii Surowic I Szczepionek Biomed Spolka Akcyjna Nowy szczep Bifidobacterium breve
MX367109B (es) 2013-11-25 2019-08-05 Seres Therapeutics Inc Composiciones bacterianas sinergicas y sus metodos de produccion y usos.
WO2015095241A2 (en) 2013-12-16 2015-06-25 Seres Health, Inc. Bacterial compositions and methods of use thereof for treatment of immune system disorders
CN103981115B (zh) 2013-12-24 2018-10-26 北京大伟嘉生物技术股份有限公司 一株高抗逆性屎肠球菌及其应用
CN103981117B (zh) 2013-12-24 2018-10-26 北京大伟嘉生物技术股份有限公司 一株高抗逆性屎肠球菌及其培养方法和应用
CN103820363B (zh) 2014-01-27 2016-02-24 福建省农业科学院生物技术研究所 一种屎肠球菌菌粉的制备与应用
CN103865846B (zh) 2014-02-27 2016-03-30 扬州绿保生物科技有限公司 一种屎肠球菌及其制备方法
CN103849590B (zh) 2014-03-25 2016-07-06 上海交通大学 一株耐酸短双歧杆菌BB8dpH及其应用
KR101683474B1 (ko) 2014-03-26 2016-12-08 주식회사 쎌바이오텍 과민성 대장 증후군 예방 또는 치료용 조성물
US9783858B2 (en) 2014-04-02 2017-10-10 Northwestern University Altered microbiome of chronic pelvic pain
KR101583546B1 (ko) 2014-04-09 2016-01-11 국립암센터 유전자 다형성을 이용한 소라페닙 치료에 대한 반응성 예측방법
US10300137B2 (en) 2014-04-10 2019-05-28 Riken Compositions and methods for induction of TH17 cells
CN104195075B (zh) 2014-08-14 2017-04-19 生合生物科技股份有限公司 一种屎肠球菌ef08及包含它的饲料添加物和饲料
WO2015168534A1 (en) 2014-05-02 2015-11-05 Novogy, Inc. Therapeutic treatment of gastrointestinal microbial imbalances through competitive microbe displacement
MX2016014634A (es) 2014-05-08 2017-04-10 Panoptes Pharma Ges M B H Compuestos para el tratamiento de enfermedades y trastornos oftalmicos.
WO2016019506A1 (en) 2014-08-05 2016-02-11 BGI Shenzhen Co.,Limited Use of eubacterium in the prevention and treatment for colorectal cancer related diseases
WO2016033439A2 (en) * 2014-08-28 2016-03-03 Yale University Compositions and methods for the treating an inflammatory disease or disorder
WO2016036615A1 (en) 2014-09-03 2016-03-10 California Institute Of Technology Microbe-based modulation of serotonin biosynthesis
CN104546940A (zh) 2014-09-30 2015-04-29 深圳华大基因科技有限公司 平常拟杆菌在治疗或预防类风湿性关节炎或其相关疾病中的应用
CN104546935A (zh) 2014-09-30 2015-04-29 深圳华大基因科技有限公司 多形拟杆菌在治疗或预防类风湿性关节炎或其相关疾病中的应用
CN104546942A (zh) 2014-09-30 2015-04-29 深圳华大基因科技有限公司 多氏拟杆菌在治疗或预防类风湿性关节炎或其相关疾病中的应用
CN104546932A (zh) 2014-09-30 2015-04-29 深圳华大基因科技有限公司 卵形拟杆菌在治疗或预防类风湿性关节炎或其相关疾病中的应用
CN104546934B (zh) 2014-09-30 2019-04-09 深圳华大基因科技有限公司 粪副拟杆菌在治疗或预防类风湿性关节炎或其相关疾病中的应用
CN104546933A (zh) 2014-09-30 2015-04-29 深圳华大基因科技有限公司 粪拟杆菌在治疗或预防类风湿性关节炎或其相关疾病中的应用
US10046030B2 (en) * 2014-10-07 2018-08-14 University Of Virginia Patent Foundation Compositions and methods for preventing and treating infection
CN107249611A (zh) 2014-10-24 2017-10-13 进化生物系统股份有限公司 活化的双歧杆菌及其应用方法
KR20170086492A (ko) 2014-10-30 2017-07-26 캘리포니아 인스티튜트 오브 테크놀로지 신경발달 장애에서의 행동을 개선시키기 위한 박테리아를 포함하는 조성물 및 방법
US10124025B2 (en) 2014-10-30 2018-11-13 California Institute Of Technology Compositions and methods comprising bacteria for improving behavior in neurodevelopmental disorders
EP3881680A1 (en) 2014-10-31 2021-09-22 Pendulum Therapeutics, Inc. Methods and compositions relating to microbial treatment
CN104435000A (zh) 2014-11-12 2015-03-25 江南大学 乳酸菌对支气管哮喘治疗中的应用
MA41020A (fr) 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
CN107249609A (zh) 2014-11-25 2017-10-13 纪念斯隆-凯特琳癌症中心 肠道微生物群和gvhd
EA035925B1 (ru) 2014-12-23 2020-09-01 4Д Фарма Рисерч Лимитед Полипептид и иммуномодуляция
KR101942955B1 (ko) 2014-12-23 2019-01-28 4디 파마 리서치 리미티드 면역 조정
CN104560820B (zh) 2014-12-30 2017-10-20 杭州师范大学 屎肠球菌kq2.6及应用
JP6783247B2 (ja) 2015-01-23 2020-11-11 テンプル ユニヴァーシティ − オブ ザ コモンウェルス システム オブ ハイアー エデュケーション ガン予防における短鎖脂肪酸の使用
US9878177B2 (en) * 2015-01-28 2018-01-30 Elekta Ab (Publ) Three dimensional localization and tracking for adaptive radiation therapy
IL291672B2 (en) * 2015-02-10 2024-02-01 Amgen Inc A rotary biased insertion mechanism for a drug delivery pump
US9848983B2 (en) * 2015-02-13 2017-12-26 Millipede, Inc. Valve replacement using rotational anchors
CN105982919A (zh) 2015-02-26 2016-10-05 王汉成 生物减速剂抗癌技术
WO2016139217A1 (en) 2015-03-04 2016-09-09 Ab-Biotics, S.A. Composition comprising anaerobically cultivated human intestinal microbiota
US20180078587A1 (en) 2015-03-18 2018-03-22 Trustees Of Tufts College Compositions and methods for preventing colorectal cancer
EP3270938A4 (en) 2015-03-18 2018-12-19 Whole Biome Inc. Methods and compositions relating to microbial treatment and diagnosis of skin disorders
WO2016196605A1 (en) 2015-06-01 2016-12-08 The University Of Chicago Treatment of cancer by manipulation of commensal microflora
EP3307288B1 (en) 2015-06-15 2019-07-24 4D Pharma Research Limited Compositions comprising bacterial strains
NZ777234A (en) 2015-06-15 2022-02-25 4D Pharma Res Ltd Compositions comprising bacterial strains
LT3240554T (lt) 2015-06-15 2019-11-11 4D Pharma Res Ltd Blautia stercosis ir wexlerae, skirtos naudoti uždegiminių ir autoimuninių ligų gydymui
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
CN105112333A (zh) 2015-08-31 2015-12-02 江南大学 一种具有良好肠道定殖能力的长双歧杆菌及筛选方法和应用
ES2662617T3 (es) 2015-11-20 2018-04-09 4D Pharma Research Limited Composiciones que comprenden cepas bacterianas
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
WO2017091753A1 (en) 2015-11-25 2017-06-01 Memorial Sloan-Kettering Cancer Center Methods and compositions for reducing vancomycin-resistant enterococci infection or colonization
CN108883139B (zh) 2016-03-04 2022-04-26 4D制药有限公司 包含细菌菌株的组合物
HUE063858T2 (hu) 2016-05-31 2024-02-28 Morinaga Milk Industry Co Ltd Agyfunkciót javító szer
TW201821093A (zh) * 2016-07-13 2018-06-16 英商4D製藥有限公司 包含細菌菌株之組合物
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
US20190314427A1 (en) 2016-12-16 2019-10-17 Evelo Biosciences, Inc. Methods of treating cancer using parabacteroides
WO2018112365A2 (en) 2016-12-16 2018-06-21 Evelo Biosciences, Inc. Methods of treating colorectal cancer and melanoma using parabacteroides goldsteinii
EP3630942B1 (en) 2017-05-24 2022-11-30 4D Pharma Research Limited Compositions comprising bacterial strain

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