DK0894126T3 - Alkalisk phosphatase-deficient trådformet svamp - Google Patents

Alkalisk phosphatase-deficient trådformet svamp

Info

Publication number
DK0894126T3
DK0894126T3 DK97914177T DK97914177T DK0894126T3 DK 0894126 T3 DK0894126 T3 DK 0894126T3 DK 97914177 T DK97914177 T DK 97914177T DK 97914177 T DK97914177 T DK 97914177T DK 0894126 T3 DK0894126 T3 DK 0894126T3
Authority
DK
Denmark
Prior art keywords
filamentous fungus
alkaline phosphatase
fungi
production
methods
Prior art date
Application number
DK97914177T
Other languages
English (en)
Inventor
Jan Lehmbeck
Original Assignee
Novozymes As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes As filed Critical Novozymes As
Application granted granted Critical
Publication of DK0894126T3 publication Critical patent/DK0894126T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/60—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Botany (AREA)
  • Virology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Detergent Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Mushroom Cultivation (AREA)
DK97914177T 1996-03-27 1997-03-26 Alkalisk phosphatase-deficient trådformet svamp DK0894126T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK35496 1996-03-27
DK55596 1996-05-09
EP97914177A EP0894126B1 (en) 1996-03-27 1997-03-26 Alkaline protease deficient filamentous fungi

Publications (1)

Publication Number Publication Date
DK0894126T3 true DK0894126T3 (da) 2006-06-12

Family

ID=26063843

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97914177T DK0894126T3 (da) 1996-03-27 1997-03-26 Alkalisk phosphatase-deficient trådformet svamp

Country Status (10)

Country Link
US (1) US6291209B1 (da)
EP (1) EP0894126B1 (da)
JP (1) JP4263241B2 (da)
CN (1) CN1120235C (da)
AT (1) ATE317005T1 (da)
AU (1) AU2152897A (da)
DE (1) DE69735199T2 (da)
DK (1) DK0894126T3 (da)
ES (1) ES2257774T3 (da)
WO (1) WO1997035956A1 (da)

Families Citing this family (63)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4091119B2 (ja) 1996-09-19 2008-05-28 ノボザイムス アクティーゼルスカブ 新規な宿主細胞およびタンパク質生産方法
US6806062B1 (en) 1998-10-05 2004-10-19 Novozymes A/S Fungal transcriptional activator useful in methods for producing polypeptides
DK1117798T3 (da) * 1998-10-05 2007-04-10 Novozymes As Fungal transskriptionel aktivator egnet ved fremgangsmåder til produktion af polypeptider
TR200101497T2 (tr) 1998-11-27 2001-11-21 Novozymes A/S Lipolitik enzim varyantları
CN100510067C (zh) 1999-07-09 2009-07-08 诺维信公司 葡糖淀粉酶变体
EP1980614A3 (en) 1999-11-10 2009-04-08 Novozymes A/S Fungamyl-like Alpha-Amylase Variants
JP2003526374A (ja) 2000-03-14 2003-09-09 ノボザイムス アクティーゼルスカブ ポリペプチドの生成方法において有用な菌類転写活性化因子
EP2287296A1 (en) 2000-06-26 2011-02-23 Novozymes A/S Lipolytic enzyme
EP1840211A1 (en) 2001-10-31 2007-10-03 Danisco A/S Pyranosone dehydratase from phanerochaete chrysosporium
EP1474508B1 (en) 2002-02-08 2011-11-16 Novozymes A/S Phytase variants
ATE347591T1 (de) 2002-12-17 2006-12-15 Novozymes As Thermostabile alpha-amylase
CA2593282C (en) 2005-01-10 2016-03-15 Novozymes A/S Production of fatty acid alkyl esters by use of two lipolytic enzymes
JP2008527985A (ja) 2005-01-24 2008-07-31 ディーエスエム アイピー アセッツ ビー．ブイ． 糸状菌細胞において目的の化合物を産生させるための方法
AP2007004141A0 (en) 2005-03-16 2007-08-31 Novozymes As Recombinant expression of defensins in filamentousfunti
CN101292024B (zh) 2005-10-17 2012-04-18 诺维信公司 用于表达抗体的真菌突变体的用途
US20080280328A1 (en) 2005-11-18 2008-11-13 Novozymes A/S Glucoamylase Variants
JP5250850B2 (ja) 2006-06-29 2013-07-31 ディーエスエム アイピー アセッツ ビー．ブイ． 改善されたポリペプチド発現を達成する方法
CA2680273C (en) 2007-03-09 2017-02-28 Novozymes A/S Thermostable asparaginases
WO2009043854A1 (en) * 2007-10-01 2009-04-09 Novozymes A/S Polypeptides having protease activity and polynucleotides encoding same
EP2281034B1 (en) 2008-04-30 2015-10-21 DuPont Nutrition Biosciences ApS Process using Pseudoglucanobacter saccharoketogenes alcohol dehydrogenase
JP5305353B2 (ja) * 2009-06-23 2013-10-02 ヤマサ醤油株式会社 ａｌｐＢをコードする遺伝子の機能が欠損している麹菌及びその利用
GB201011513D0 (en) 2010-07-08 2010-08-25 Danisco Method
US20130302878A1 (en) 2011-01-20 2013-11-14 Novozymes A/S Expression of plant peroxidases in filamentous fungi
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
AR087980A1 (es) * 2011-09-22 2014-04-30 Danisco Us Inc Actividad de dnasa endogena para reducir el contenido de adn
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
CA2861697C (en) 2012-01-05 2022-03-15 Novartis Ag Protease deficient filamentous fungal cells and methods of use thereof
US9695454B2 (en) 2012-05-23 2017-07-04 Glykos Finland Oy Production of fucosylated glycoproteins
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
RU2016104064A (ru) 2013-07-10 2017-08-15 Новартис Аг Клетки мицелиальных грибов с множественной недостаточностью протеаз и способы их использования
JP6368968B2 (ja) * 2014-01-22 2018-08-08 本田技研工業株式会社 形質転換体の製造方法、糖化酵素の生産方法、及び草木類バイオマスの糖化処理方法
US10513724B2 (en) 2014-07-21 2019-12-24 Glykos Finland Oy Production of glycoproteins with mammalian-like N-glycans in filamentous fungi
EP3172329A1 (en) 2014-10-24 2017-05-31 Danisco US Inc. Method for producing alcohol by use of a tripeptidyl peptidase
AU2015334890B2 (en) 2014-10-24 2021-12-23 Dupont Nutrition Biosciences Aps Proline tolerant tripeptidyl peptidases and uses thereof
JP6360787B2 (ja) * 2014-12-04 2018-07-18 本田技研工業株式会社 麹菌変異株及び形質転換体
EP3395351A1 (en) 2014-12-23 2018-10-31 4D Pharma Research Limited Immune modulation
JP6427278B2 (ja) 2014-12-23 2018-11-21 フォーディー ファーマ リサーチ リミテッド４Ｄ Ｐｈａｒｍａ Ｒｅｓｅａｒｃｈ Ｌｉｍｉｔｅｄ ｐｉｒｉｎポリペプチド及び免疫モジュレーション
CN106190874B (zh) * 2015-05-06 2020-06-26 中国科学院天津工业生物技术研究所 一种强化丝状真菌蛋白质生产的方法
BR112017025005A2 (pt) 2015-06-15 2018-08-07 4D Pharma Research Limited composições compreendendo cepas baterianas
PT3650033T (pt) 2015-06-15 2022-05-25 4D Pharma Res Ltd Composições compreendendo estirpes bacterianas
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
CN107847529B (zh) 2015-06-15 2022-05-03 4D制药研究有限公司 包含细菌菌株的组合物
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
EP3064589A1 (en) 2015-07-29 2016-09-07 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Enzymatic process for the preparation of testosterone and esters thereof
MA41013A (fr) 2015-11-20 2017-08-30 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
MX2018009216A (es) 2016-02-25 2018-11-09 Dupont Nutrition Biosci Aps Metodo para producir un hidrolizado de proteina empleando una tripeptidil peptidasa de aspergillus fumigatus.
EA035949B1 (ru) 2016-03-04 2020-09-04 4Д ФАРМА ПиЭлСи Применение композиции, содержащей бактериальный штамм вида blautia hydrogenotrophica, и способ лечения или предотвращения висцеральной гиперчувствительности
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
TW201821093A (zh) 2016-07-13 2018-06-16 英商４Ｄ製藥有限公司 包含細菌菌株之組合物
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
MA48939B1 (fr) 2017-05-22 2021-06-30 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
WO2018215782A1 (en) 2017-05-24 2018-11-29 4D Pharma Research Limited Compositions comprising bacterial strain
MD3600364T2 (ro) 2017-06-14 2020-12-31 4D Pharma Res Ltd Compoziții care conţin tulpină bacteriană din genul Megasphaera și utilizări ale acestora
HUE053488T2 (hu) 2017-06-14 2021-06-28 4D Pharma Res Ltd Baktériumtörzseket tartalmazó készítmények
LT3638271T (lt) 2017-06-14 2021-01-11 4D Pharma Research Limited Kompozicijos, apimančios bakterines padermes
AU2018348518B2 (en) 2017-10-10 2024-05-16 Ajinomoto Co., Inc. Method for manufacturing protein
CA3182806A1 (en) * 2020-05-14 2021-11-18 Dyadic International (Usa), Inc. Modified filamentous fungi for production of exogenous proteins
EP4166647A1 (en) 2020-06-11 2023-04-19 Ajinomoto Co., Inc. Method for producing protein
CN112725399B (zh) * 2020-12-29 2023-04-11 海南云皓生物科技有限公司 一种香菇寡肽的制备方法及用途
AU2023259645A1 (en) 2022-04-29 2024-09-05 Novozymes A/S Production of fatty acid alkyl esters

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1333777C (en) * 1988-07-01 1995-01-03 Randy M. Berka Aspartic proteinase deficient filamentous fungi
EP0414297B1 (en) * 1989-08-11 1996-10-16 Gist-Brocades N.V. Efficient production of mutant proteases
WO1992017595A1 (en) * 1991-04-01 1992-10-15 The Salk Institute Biotechnology/Industrial Associates, Inc. Genes which influence pichia proteolytic activity, and uses therefor
ES2208637T3 (es) * 1992-04-15 2004-06-16 Novartis Ag Nueva proteasa fungica.

Also Published As

Publication number Publication date
DE69735199T2 (de) 2006-09-21
ES2257774T3 (es) 2006-08-01
JP2000507106A (ja) 2000-06-13
EP0894126A1 (en) 1999-02-03
JP4263241B2 (ja) 2009-05-13
WO1997035956A1 (en) 1997-10-02
EP0894126B1 (en) 2006-02-01
AU2152897A (en) 1997-10-17
CN1120235C (zh) 2003-09-03
US6291209B1 (en) 2001-09-18
DE69735199D1 (de) 2006-04-13
CN1214731A (zh) 1999-04-21
ATE317005T1 (de) 2006-02-15

Similar Documents

Publication Publication Date Title
DK0894126T3 (da) Alkalisk phosphatase-deficient trådformet svamp
DE69739996D1 (de) Methoden und Zusammensetzungen zur Herstellung von Polypeptiden
ATE317441T1 (de) Cathepsin-02-protease
ATE454393T1 (de) Egvii-endoglucanase und dafür codierende nukleinsäuren
LV10309A (lv) Panemiens rekombinanto olbaltumvielu fermentativai skelsanai ar IgA proteazem savienota olbaltumviela rekombinanta DNS suna
DE69826465D1 (de) Verfahren zur in vitro evolution von proteinfunktionen
DK1117808T3 (da) Transformaationssystem inden jfjor området filamentöse svampeværter: I chrysosporium
NO952989L (no) Fremgangsmåte til refolding av proteiner
HUP0301659A2 (hu) Kukorica cellulóz-szintetázok és alkalmazásuk
ATE313620T1 (de) Wirtszellen und methoden für die produktion von proteinen
FI19991781A (fi) Parannettu biotekninen tuotantomenetelmä
ES2148168T3 (es) Proceso para la produccion de proteinas peroxidasas de una cepa de aspergillus.
ES2129487T3 (es) Peptidos sinteticos, anticuerpos dirigidos contra ellos y su utilizacion.
ATE457352T1 (de) Subtilisin-carlsberg-proteine mit verminderter immunogenität
NO20053033D0 (no) Anvendelse av caspase enzymer for modning av konstruerte rekombinante polypeptidfusjoner.
ATE360695T1 (de) Cortistatin: neuropeptide, zusammensetzungen und methoden
NO931368L (no) Sopp-protease
DK0655497T3 (da) Svampeprotease
DE69634757D1 (de) Vektor zur expression von n-terminal verlängerten proteinen in hefezellen
PT1379639E (pt) A glucuranilo epimerase c5 o dna que a codifica e as suas utilizacoes
IL104003A0 (en) Recombinant vaccines and method of producing same
DE69202858D1 (de) Herstellungsverfahren für chymosin.