DE69735199D1 - Alkaline-phosphatase-defiziente, filamentöse pilze - Google Patents

Alkaline-phosphatase-defiziente, filamentöse pilze

Info

Publication number
DE69735199D1
DE69735199D1 DE69735199T DE69735199T DE69735199D1 DE 69735199 D1 DE69735199 D1 DE 69735199D1 DE 69735199 T DE69735199 T DE 69735199T DE 69735199 T DE69735199 T DE 69735199T DE 69735199 D1 DE69735199 D1 DE 69735199D1
Authority
DE
Germany
Prior art keywords
alkaline phosphatase
fungi
production
methods
filamentous mushrooms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69735199T
Other languages
English (en)
Other versions
DE69735199T2 (de
Inventor
Jan Lehmbeck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novozymes AS
Original Assignee
Novozymes AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novozymes AS filed Critical Novozymes AS
Publication of DE69735199D1 publication Critical patent/DE69735199D1/de
Application granted granted Critical
Publication of DE69735199T2 publication Critical patent/DE69735199T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/145—Fungal isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/60—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/645—Fungi ; Processes using fungi
DE69735199T 1996-03-27 1997-03-26 Alkaline-phosphatase-defiziente, filamentöse pilze Expired - Lifetime DE69735199T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
DK35496 1996-03-27
DK35496 1996-03-27
DK55596 1996-05-09
DK55596 1996-05-09
PCT/DK1997/000135 WO1997035956A1 (en) 1996-03-27 1997-03-26 Alkaline protease deficient filamentous fungi

Publications (2)

Publication Number Publication Date
DE69735199D1 true DE69735199D1 (de) 2006-04-13
DE69735199T2 DE69735199T2 (de) 2006-09-21

Family

ID=26063843

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69735199T Expired - Lifetime DE69735199T2 (de) 1996-03-27 1997-03-26 Alkaline-phosphatase-defiziente, filamentöse pilze

Country Status (10)

Country Link
US (1) US6291209B1 (de)
EP (1) EP0894126B1 (de)
JP (1) JP4263241B2 (de)
CN (1) CN1120235C (de)
AT (1) ATE317005T1 (de)
AU (1) AU2152897A (de)
DE (1) DE69735199T2 (de)
DK (1) DK0894126T3 (de)
ES (1) ES2257774T3 (de)
WO (1) WO1997035956A1 (de)

Families Citing this family (62)

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JP4091119B2 (ja) 1996-09-19 2008-05-28 ノボザイムス アクティーゼルスカブ 新規な宿主細胞およびタンパク質生産方法
JP4563585B2 (ja) * 1998-10-05 2010-10-13 ノボザイムス アクティーゼルスカブ ポリペプチドの生成方法において有用な菌類転写活性化因子
US6806062B1 (en) 1998-10-05 2004-10-19 Novozymes A/S Fungal transcriptional activator useful in methods for producing polypeptides
EP2302044A1 (de) 1998-11-27 2011-03-30 Novozymes A/S Varianten eines lipolytischen Enzyms
AU5805700A (en) 1999-07-09 2001-01-30 Novozymes A/S Glucoamylase variant
JP2003513666A (ja) 1999-11-10 2003-04-15 ノボザイムス アクティーゼルスカブ フンガミル様アルファ−アミラーゼ変異体
CN1425068B (zh) 2000-03-14 2011-05-18 诺维信公司 在制备多肽的方法中有效的真菌转录激活因子
EP2281878A1 (de) 2000-06-26 2011-02-09 Novozymes A/S Lipolytisches Enzym
EP1840211A1 (de) 2001-10-31 2007-10-03 Danisco A/S Pyranoson Dehydratase aus phanerochaete Chrysosporium
JP4426307B2 (ja) 2002-02-08 2010-03-03 ノボザイムス アクティーゼルスカブ フィターゼ変異体
ES2278210T3 (es) * 2002-12-17 2007-08-01 Novozymes A/S Alfa-amilasas termoestables.
US20080113419A1 (en) 2005-01-10 2008-05-15 Novozymes A/S Production of Fatty Acid Alkyl Esters by Use of Two Lipolytic Enzymes
CA2595056A1 (en) 2005-01-24 2006-07-27 Dsm Ip Assets B.V. Method for producing a compound of interest in a filamentous fungal cell
WO2006097464A1 (en) 2005-03-16 2006-09-21 Novozymes A/S Recombinant expression of defensins in filamentous fungi
ATE514770T1 (de) 2005-10-17 2011-07-15 Novozymes As Verwendung von pilzmutanten zur expression von antikörpern
US20080280328A1 (en) 2005-11-18 2008-11-13 Novozymes A/S Glucoamylase Variants
EP2035561A1 (de) 2006-06-29 2009-03-18 DSMIP Assets B.V. Verfahren für verbesserte polypeptidexpression
EP2851424B1 (de) 2007-03-09 2016-09-21 Novozymes A/S Thermostabile Asparaginasen
US8383391B2 (en) 2007-10-01 2013-02-26 Novozymes A/S Mutant cell with deleted or disrupted genes encoding protease
WO2009133464A2 (en) 2008-04-30 2009-11-05 Danisco A/S Oxidation process
JP5305353B2 (ja) * 2009-06-23 2013-10-02 ヤマサ醤油株式会社 ａｌｐＢをコードする遺伝子の機能が欠損している麹菌及びその利用
GB201011513D0 (en) 2010-07-08 2010-08-25 Danisco Method
CN103443268A (zh) 2011-01-20 2013-12-11 诺维信公司 植物过氧化物酶在丝状真菌中的表达
GB201112091D0 (en) 2011-07-14 2011-08-31 Gt Biolog Ltd Bacterial strains isolated from pigs
WO2013043860A1 (en) * 2011-09-22 2013-03-28 Danisco Us Inc. Endogenous dnase activity to reduce dna content
GB201117313D0 (en) 2011-10-07 2011-11-16 Gt Biolog Ltd Bacterium for use in medicine
CA2861697C (en) 2012-01-05 2022-03-15 Novartis Ag Protease deficient filamentous fungal cells and methods of use thereof
US9695454B2 (en) 2012-05-23 2017-07-04 Glykos Finland Oy Production of fucosylated glycoproteins
GB201306536D0 (en) 2013-04-10 2013-05-22 Gt Biolog Ltd Polypeptide and immune modulation
CA2916905A1 (en) 2013-07-10 2015-01-15 Novartis Ag Multiple proteases deficient filamentous fungal cells and methods of use thereof
JP6368968B2 (ja) * 2014-01-22 2018-08-08 本田技研工業株式会社 形質転換体の製造方法、糖化酵素の生産方法、及び草木類バイオマスの糖化処理方法
AU2015293949B2 (en) 2014-07-21 2019-07-25 Teknologian Tutkimuskeskus Vtt Oy Production of glycoproteins with mammalian-like N-glycans in filamentous fungi
US20170306360A1 (en) 2014-10-24 2017-10-26 Danisco Us Inc. Method for producing alcohol by use of a tripeptidyl peptidase
EP3209774B1 (de) 2014-10-24 2020-02-26 DuPont Nutrition Biosciences ApS Verwendung von prolintoleranten tripeptidylpeptidasen in futterzusatzzusammensetzungen
JP6360787B2 (ja) * 2014-12-04 2018-07-18 本田技研工業株式会社 麹菌変異株及び形質転換体
CN108138122B (zh) 2014-12-23 2021-09-21 4D制药研究有限公司 免疫调控
JP6427278B2 (ja) 2014-12-23 2018-11-21 フォーディー ファーマ リサーチ リミテッド４Ｄ Ｐｈａｒｍａ Ｒｅｓｅａｒｃｈ Ｌｉｍｉｔｅｄ ｐｉｒｉｎポリペプチド及び免疫モジュレーション
CN106190874B (zh) * 2015-05-06 2020-06-26 中国科学院天津工业生物技术研究所 一种强化丝状真菌蛋白质生产的方法
SG10201912319SA (en) 2015-06-15 2020-02-27 4D Pharma Res Ltd Compositions comprising bacterial strains
HUE045413T2 (hu) 2015-06-15 2019-12-30 4D Pharma Res Ltd Baktériumtörzseket tartalmazó készítmények
DK3240554T3 (da) 2015-06-15 2019-10-28 4D Pharma Res Ltd Blautia stercosis og wexlerae til anvendelse til behandling af inflammatoriske og autoimmune sygdomme
MA41060B1 (fr) 2015-06-15 2019-11-29 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
MA41010B1 (fr) 2015-06-15 2020-01-31 4D Pharma Res Ltd Compositions comprenant des souches bactériennes
EP3064589A1 (de) 2015-07-29 2016-09-07 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Enzymatisches verfahren zur herstellung von testosteron und ester davon
NZ742787A (en) 2015-11-20 2020-02-28 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520497D0 (en) 2015-11-20 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520638D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
GB201520631D0 (en) 2015-11-23 2016-01-06 4D Pharma Res Ltd Compositions comprising bacterial strains
WO2017147060A1 (en) 2016-02-25 2017-08-31 Dupont Nutrition Biosciences Aps Method for producing a protein hydrolysate employing an aspergillus fumigatus tripeptidyl peptidase
GB201612191D0 (en) 2016-07-13 2016-08-24 4D Pharma Plc Compositions comprising bacterial strains
ES2731579T3 (es) 2016-03-04 2019-11-18 4D Pharma Plc Composiciones que comprenden cepas de blautia bacteriana para tratar hipersensibilidad visceral
TW201821093A (zh) 2016-07-13 2018-06-16 英商４Ｄ製藥有限公司 包含細菌菌株之組合物
GB201621123D0 (en) 2016-12-12 2017-01-25 4D Pharma Plc Compositions comprising bacterial strains
RS61872B1 (sr) 2017-05-22 2021-06-30 4D Pharma Res Ltd Kompozicije koje sadrže bakterijske sojeve
JP6978514B2 (ja) 2017-05-24 2021-12-08 フォーディー ファーマ リサーチ リミテッド4D Pharma Research Limited 細菌株を含む組成物
PT3638271T (pt) 2017-06-14 2021-01-05 4D Pharma Res Ltd Composições contendo estirpes bacterianas
HRP20220747T1 (hr) 2017-06-14 2022-10-14 4D Pharma Research Limited Pripravci koji sadrže bakterijske sojeve
JP7234932B2 (ja) 2017-10-10 2023-03-08 味の素株式会社 タンパク質の製造法
EP4150050A1 (de) * 2020-05-14 2023-03-22 Dyadic International (USA), Inc. Modifizierte filamentöse pilze zur herstellung exogener proteine
JPWO2021251383A1 (de) 2020-06-11 2021-12-16
CN112725399B (zh) * 2020-12-29 2023-04-11 海南云皓生物科技有限公司 一种香菇寡肽的制备方法及用途
WO2023209070A1 (en) 2022-04-29 2023-11-02 Novozymes A/S Production of fatty acid alkyl esters

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1333777C (en) * 1988-07-01 1995-01-03 Randy M. Berka Aspartic proteinase deficient filamentous fungi
DE69028890T2 (de) * 1989-08-11 1997-02-27 Gist Brocades Nv Ergiebige Herstellung von Protease-Mutanten
CA2105064A1 (en) * 1991-04-01 1992-10-02 Martin Anthony Gleeson Genes which influence pichia proteolytic activity, and uses therefor
DE69333249T2 (de) * 1992-04-15 2004-07-29 Novartis Ag Neue Schimmel-Protease

Also Published As

Publication number Publication date
EP0894126A1 (de) 1999-02-03
DK0894126T3 (da) 2006-06-12
ES2257774T3 (es) 2006-08-01
CN1214731A (zh) 1999-04-21
JP2000507106A (ja) 2000-06-13
CN1120235C (zh) 2003-09-03
EP0894126B1 (de) 2006-02-01
JP4263241B2 (ja) 2009-05-13
ATE317005T1 (de) 2006-02-15
AU2152897A (en) 1997-10-17
WO1997035956A1 (en) 1997-10-02
DE69735199T2 (de) 2006-09-21
US6291209B1 (en) 2001-09-18

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