KR940001772B1 - α,α-디아릴-4-아릴-4-하이드록시-1-피페리딘부탄아미드 N-옥사이드유도체의 제조방법 - Google Patents

α,α-디아릴-4-아릴-4-하이드록시-1-피페리딘부탄아미드 N-옥사이드유도체의 제조방법 Download PDF

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Publication number
KR940001772B1
KR940001772B1 KR1019860008184A KR860008184A KR940001772B1 KR 940001772 B1 KR940001772 B1 KR 940001772B1 KR 1019860008184 A KR1019860008184 A KR 1019860008184A KR 860008184 A KR860008184 A KR 860008184A KR 940001772 B1 KR940001772 B1 KR 940001772B1
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KR
South Korea
Prior art keywords
hydroxy
piperidinebutanamide
diphenyl
acid
dimethyl
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
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KR1019860008184A
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English (en)
Korean (ko)
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KR870003986A (ko
Inventor
왈스 로우렌스
폴 쿠이맨스 루드윅
Original Assignee
쟈안센 파아마슈우티카 엔. 부이.
폴 아드리안 쟌 쟈안센
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Application filed by 쟈안센 파아마슈우티카 엔. 부이., 폴 아드리안 쟌 쟈안센 filed Critical 쟈안센 파아마슈우티카 엔. 부이.
Publication of KR870003986A publication Critical patent/KR870003986A/ko
Application granted granted Critical
Publication of KR940001772B1 publication Critical patent/KR940001772B1/ko
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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/94—Oxygen atom, e.g. piperidine N-oxide

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Electric Double-Layer Capacitors Or The Like (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Compositions Of Oxide Ceramics (AREA)
KR1019860008184A 1985-10-11 1986-09-30 α,α-디아릴-4-아릴-4-하이드록시-1-피페리딘부탄아미드 N-옥사이드유도체의 제조방법 Expired - Lifetime KR940001772B1 (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US78656685A 1985-10-11 1985-10-11
US786,566 1985-10-11
US786566 1985-10-11

Publications (2)

Publication Number Publication Date
KR870003986A KR870003986A (ko) 1987-05-06
KR940001772B1 true KR940001772B1 (ko) 1994-03-05

Family

ID=25138953

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019860008184A Expired - Lifetime KR940001772B1 (ko) 1985-10-11 1986-09-30 α,α-디아릴-4-아릴-4-하이드록시-1-피페리딘부탄아미드 N-옥사이드유도체의 제조방법

Country Status (33)

Country Link
EP (1) EP0219898B1 (enExample)
JP (1) JPS6287569A (enExample)
KR (1) KR940001772B1 (enExample)
CN (1) CN1015453B (enExample)
AT (1) ATE53022T1 (enExample)
AU (1) AU583429B2 (enExample)
BG (1) BG61320B2 (enExample)
CA (1) CA1332236C (enExample)
CY (1) CY1603A (enExample)
DE (1) DE3671442D1 (enExample)
DK (1) DK173954B1 (enExample)
DZ (1) DZ997A1 (enExample)
EG (1) EG18126A (enExample)
ES (1) ES2002001A6 (enExample)
FI (1) FI83642C (enExample)
GR (1) GR862493B (enExample)
HK (1) HK52491A (enExample)
HU (1) HU196180B (enExample)
IE (1) IE59519B1 (enExample)
IL (1) IL80268A (enExample)
LT (1) LT2086B (enExample)
LV (2) LV5042A3 (enExample)
NL (1) NL950025I2 (enExample)
NO (2) NO168640C (enExample)
NZ (1) NZ217818A (enExample)
PH (1) PH22510A (enExample)
PT (1) PT83506B (enExample)
SG (1) SG46291G (enExample)
SU (1) SU1443798A3 (enExample)
TN (1) TNSN86138A1 (enExample)
ZA (1) ZA867713B (enExample)
ZM (1) ZM9486A1 (enExample)
ZW (1) ZW20386A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101315751B1 (ko) * 2011-05-30 2013-10-10 주식회사 엔지켐생명과학 로페라미드 옥사이드 모노하이드레이트의 신규한 제조방법

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2088273C (en) * 1990-08-09 1996-05-14 Daniel Louis Barone Processes for formulating a solid oral dosage form of loperamide compounds
US5434158A (en) * 1994-04-26 1995-07-18 Merck & Co., Inc. Spiro-substituted azacycles as neurokinin-3 antagonists
AU1208397A (en) * 1995-12-28 1997-07-28 Takeda Chemical Industries Ltd. Diphenylmethane derivatives as mip-1alpha/rantes receptor antagonists
TR200002570T2 (tr) * 1998-03-06 2000-12-21 Janssen Pharmaceutica N.V. Glisin naklini önleyiciler

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3714159A (en) * 1971-03-30 1973-01-30 Janssen Pharmaceutica Nv 2,2-diaryl-4-(4'-aryl-4'-hydroxy-piper-idino)-butyramides
US4002618A (en) * 1976-02-23 1977-01-11 G. D. Searle & Co. 2,2-Diphenyl-5-(4-substituted-piperidino)-3-trans-pentenenitriles

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101315751B1 (ko) * 2011-05-30 2013-10-10 주식회사 엔지켐생명과학 로페라미드 옥사이드 모노하이드레이트의 신규한 제조방법

Also Published As

Publication number Publication date
DE3671442D1 (de) 1990-06-28
LV5767A4 (lv) 1996-12-20
NL950025I2 (nl) 1997-03-03
EP0219898A1 (en) 1987-04-29
EP0219898B1 (en) 1990-05-23
NO1996010I1 (no) 1996-08-06
ZM9486A1 (en) 1988-04-29
LT2086B (lt) 1993-07-15
ATE53022T1 (de) 1990-06-15
IL80268A (en) 1991-03-10
TNSN86138A1 (fr) 1990-01-01
ZA867713B (en) 1988-05-25
PT83506A (en) 1986-11-01
BG61320B2 (bg) 1997-05-30
FI864099A0 (fi) 1986-10-10
SG46291G (en) 1991-07-26
NO864045L (no) 1987-04-13
DK486886A (da) 1987-04-12
JPS6287569A (ja) 1987-04-22
NO168640B (no) 1991-12-09
FI83642B (fi) 1991-04-30
NO168640C (no) 1992-03-18
CY1603A (en) 1992-04-03
JPH0517909B2 (enExample) 1993-03-10
IE862677L (en) 1987-04-11
PH22510A (en) 1988-09-12
HK52491A (en) 1991-07-19
ZW20386A1 (en) 1988-05-11
DK173954B1 (da) 2002-03-04
AU583429B2 (en) 1989-04-27
FI83642C (fi) 1991-08-12
DK486886D0 (da) 1986-10-10
IL80268A0 (en) 1987-01-30
NZ217818A (en) 1989-03-29
LV5042A3 (lv) 1993-06-10
DZ997A1 (fr) 2004-09-13
CN1015453B (zh) 1992-02-12
EG18126A (en) 1992-08-30
KR870003986A (ko) 1987-05-06
ES2002001A6 (es) 1988-07-01
GR862493B (en) 1987-02-03
IE59519B1 (en) 1994-03-09
FI864099L (fi) 1987-04-12
PT83506B (pt) 1989-02-28
CN86106848A (zh) 1987-04-08
NL950025I1 (enExample) 1996-01-02
NO864045D0 (no) 1986-10-10
LV5767B4 (lv) 1997-06-20
SU1443798A3 (ru) 1988-12-07
AU6381586A (en) 1987-04-16
HUT42444A (en) 1987-07-28
CA1332236C (en) 1994-10-04
HU196180B (en) 1988-10-28

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