LV5767B4 - Jauni alfa alfa-diaril-4-aril-4-hidroksi-1-piperidin-butanamid,N-oksidi - Google Patents

Jauni alfa alfa-diaril-4-aril-4-hidroksi-1-piperidin-butanamid,N-oksidi

Info

Publication number
LV5767B4
LV5767B4 LV960189A LV960189A LV5767B4 LV 5767 B4 LV5767 B4 LV 5767B4 LV 960189 A LV960189 A LV 960189A LV 960189 A LV960189 A LV 960189A LV 5767 B4 LV5767 B4 LV 5767B4
Authority
LV
Latvia
Prior art keywords
6alkyl
compounds
diaryl
aryl
hydroxy
Prior art date
Application number
LV960189A
Other languages
English (en)
Other versions
LV5767A4 (lv
Inventor
Lourens Wals
Ludwig Paul Cooymans
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of LV5767A4 publication Critical patent/LV5767A4/lv
Publication of LV5767B4 publication Critical patent/LV5767B4/lv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/94—Oxygen atom, e.g. piperidine N-oxide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Electric Double-Layer Capacitors Or The Like (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
LV960189A 1985-10-11 1996-06-18 Jauni alfa alfa-diaril-4-aril-4-hidroksi-1-piperidin-butanamid,N-oksidi LV5767B4 (lv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78656685A 1985-10-11 1985-10-11
EP86201676A EP0219898B1 (en) 1985-10-11 1986-09-30 Novel alpha,alpha-diaryl-4-aryl-4-hydroxy-1-piperidinebutanamide, n-oxides

Publications (2)

Publication Number Publication Date
LV5767A4 LV5767A4 (lv) 1996-12-20
LV5767B4 true LV5767B4 (lv) 1997-06-20

Family

ID=25138953

Family Applications (2)

Application Number Title Priority Date Filing Date
LV920227A LV5042A3 (lv) 1985-10-11 1992-11-27 Alpha,alpha-difenil-4-aril-4-oksi-1-piperidinbutanamid- N-oksidu vai to stereoizomeru iegusanas metode
LV960189A LV5767B4 (lv) 1985-10-11 1996-06-18 Jauni alfa alfa-diaril-4-aril-4-hidroksi-1-piperidin-butanamid,N-oksidi

Family Applications Before (1)

Application Number Title Priority Date Filing Date
LV920227A LV5042A3 (lv) 1985-10-11 1992-11-27 Alpha,alpha-difenil-4-aril-4-oksi-1-piperidinbutanamid- N-oksidu vai to stereoizomeru iegusanas metode

Country Status (33)

Country Link
EP (1) EP0219898B1 (lv)
JP (1) JPS6287569A (lv)
KR (1) KR940001772B1 (lv)
CN (1) CN1015453B (lv)
AT (1) ATE53022T1 (lv)
AU (1) AU583429B2 (lv)
BG (1) BG61320B2 (lv)
CA (1) CA1332236C (lv)
CY (1) CY1603A (lv)
DE (1) DE3671442D1 (lv)
DK (1) DK173954B1 (lv)
DZ (1) DZ997A1 (lv)
EG (1) EG18126A (lv)
ES (1) ES2002001A6 (lv)
FI (1) FI83642C (lv)
GR (1) GR862493B (lv)
HK (1) HK52491A (lv)
HU (1) HU196180B (lv)
IE (1) IE59519B1 (lv)
IL (1) IL80268A (lv)
LT (1) LT2086B (lv)
LV (2) LV5042A3 (lv)
NL (1) NL950025I2 (lv)
NO (2) NO168640C (lv)
NZ (1) NZ217818A (lv)
PH (1) PH22510A (lv)
PT (1) PT83506B (lv)
SG (1) SG46291G (lv)
SU (1) SU1443798A3 (lv)
TN (1) TNSN86138A1 (lv)
ZA (1) ZA867713B (lv)
ZM (1) ZM9486A1 (lv)
ZW (1) ZW20386A1 (lv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2088273C (en) * 1990-08-09 1996-05-14 Daniel Louis Barone Processes for formulating a solid oral dosage form of loperamide compounds
US5434158A (en) * 1994-04-26 1995-07-18 Merck & Co., Inc. Spiro-substituted azacycles as neurokinin-3 antagonists
WO1997024325A1 (en) * 1995-12-28 1997-07-10 Takeda Chemical Industries, Ltd. DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS
AU3254499A (en) * 1998-03-06 1999-09-20 Janssen Pharmaceutica N.V. Glycine transport inhibitors
KR101315751B1 (ko) * 2011-05-30 2013-10-10 주식회사 엔지켐생명과학 로페라미드 옥사이드 모노하이드레이트의 신규한 제조방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3714159A (en) * 1971-03-30 1973-01-30 Janssen Pharmaceutica Nv 2,2-diaryl-4-(4'-aryl-4'-hydroxy-piper-idino)-butyramides
US4002618A (en) * 1976-02-23 1977-01-11 G. D. Searle & Co. 2,2-Diphenyl-5-(4-substituted-piperidino)-3-trans-pentenenitriles

Also Published As

Publication number Publication date
SG46291G (en) 1991-07-26
FI864099A (fi) 1987-04-12
EP0219898B1 (en) 1990-05-23
KR940001772B1 (ko) 1994-03-05
FI864099A0 (fi) 1986-10-10
IE862677L (en) 1987-04-11
HU196180B (en) 1988-10-28
IE59519B1 (en) 1994-03-09
ZA867713B (en) 1988-05-25
NO1996010I1 (no) 1996-08-06
ZM9486A1 (en) 1988-04-29
ZW20386A1 (en) 1988-05-11
KR870003986A (ko) 1987-05-06
PT83506A (en) 1986-11-01
FI83642C (fi) 1991-08-12
EG18126A (en) 1992-08-30
LV5042A3 (lv) 1993-06-10
LT2086B (lt) 1993-07-15
JPS6287569A (ja) 1987-04-22
DK173954B1 (da) 2002-03-04
NZ217818A (en) 1989-03-29
DE3671442D1 (de) 1990-06-28
IL80268A0 (en) 1987-01-30
DZ997A1 (fr) 2004-09-13
CA1332236C (en) 1994-10-04
CY1603A (en) 1992-04-03
SU1443798A3 (ru) 1988-12-07
NO168640C (no) 1992-03-18
DK486886A (da) 1987-04-12
ATE53022T1 (de) 1990-06-15
PH22510A (en) 1988-09-12
HUT42444A (en) 1987-07-28
DK486886D0 (da) 1986-10-10
GR862493B (en) 1987-02-03
NL950025I2 (nl) 1997-03-03
ES2002001A6 (es) 1988-07-01
PT83506B (pt) 1989-02-28
AU6381586A (en) 1987-04-16
HK52491A (en) 1991-07-19
AU583429B2 (en) 1989-04-27
FI83642B (fi) 1991-04-30
EP0219898A1 (en) 1987-04-29
TNSN86138A1 (fr) 1990-01-01
NO168640B (no) 1991-12-09
JPH0517909B2 (lv) 1993-03-10
NO864045D0 (no) 1986-10-10
BG61320B2 (bg) 1997-05-30
NL950025I1 (lv) 1996-01-02
CN86106848A (zh) 1987-04-08
IL80268A (en) 1991-03-10
CN1015453B (zh) 1992-02-12
LV5767A4 (lv) 1996-12-20
NO864045L (no) 1987-04-13

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