IL80268A - Alpha,alpha-diaryl-4-aryl-4-hydroxy-1-piperidinebutanamide n-oxides,their preparation and pharmaceutical compositions containing them - Google Patents

Alpha,alpha-diaryl-4-aryl-4-hydroxy-1-piperidinebutanamide n-oxides,their preparation and pharmaceutical compositions containing them

Info

Publication number
IL80268A
IL80268A IL80268A IL8026886A IL80268A IL 80268 A IL80268 A IL 80268A IL 80268 A IL80268 A IL 80268A IL 8026886 A IL8026886 A IL 8026886A IL 80268 A IL80268 A IL 80268A
Authority
IL
Israel
Prior art keywords
alpha
pharmaceutical compositions
6alkyl
piperidinebutanamide
diaryl
Prior art date
Application number
IL80268A
Other languages
English (en)
Other versions
IL80268A0 (en
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of IL80268A0 publication Critical patent/IL80268A0/xx
Publication of IL80268A publication Critical patent/IL80268A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/94—Oxygen atom, e.g. piperidine N-oxide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Electric Double-Layer Capacitors Or The Like (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Compositions Of Oxide Ceramics (AREA)
IL80268A 1985-10-11 1986-10-09 Alpha,alpha-diaryl-4-aryl-4-hydroxy-1-piperidinebutanamide n-oxides,their preparation and pharmaceutical compositions containing them IL80268A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78656685A 1985-10-11 1985-10-11

Publications (2)

Publication Number Publication Date
IL80268A0 IL80268A0 (en) 1987-01-30
IL80268A true IL80268A (en) 1991-03-10

Family

ID=25138953

Family Applications (1)

Application Number Title Priority Date Filing Date
IL80268A IL80268A (en) 1985-10-11 1986-10-09 Alpha,alpha-diaryl-4-aryl-4-hydroxy-1-piperidinebutanamide n-oxides,their preparation and pharmaceutical compositions containing them

Country Status (33)

Country Link
EP (1) EP0219898B1 (xx)
JP (1) JPS6287569A (xx)
KR (1) KR940001772B1 (xx)
CN (1) CN1015453B (xx)
AT (1) ATE53022T1 (xx)
AU (1) AU583429B2 (xx)
BG (1) BG61320B2 (xx)
CA (1) CA1332236C (xx)
CY (1) CY1603A (xx)
DE (1) DE3671442D1 (xx)
DK (1) DK173954B1 (xx)
DZ (1) DZ997A1 (xx)
EG (1) EG18126A (xx)
ES (1) ES2002001A6 (xx)
FI (1) FI83642C (xx)
GR (1) GR862493B (xx)
HK (1) HK52491A (xx)
HU (1) HU196180B (xx)
IE (1) IE59519B1 (xx)
IL (1) IL80268A (xx)
LT (1) LT2086B (xx)
LV (2) LV5042A3 (xx)
NL (1) NL950025I2 (xx)
NO (2) NO168640C (xx)
NZ (1) NZ217818A (xx)
PH (1) PH22510A (xx)
PT (1) PT83506B (xx)
SG (1) SG46291G (xx)
SU (1) SU1443798A3 (xx)
TN (1) TNSN86138A1 (xx)
ZA (1) ZA867713B (xx)
ZM (1) ZM9486A1 (xx)
ZW (1) ZW20386A1 (xx)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992002223A1 (en) * 1990-08-09 1992-02-20 The Procter & Gamble Company Process for formulating a solid oral dosage form of loperamide compounds
US5434158A (en) * 1994-04-26 1995-07-18 Merck & Co., Inc. Spiro-substituted azacycles as neurokinin-3 antagonists
WO1997024325A1 (en) * 1995-12-28 1997-07-10 Takeda Chemical Industries, Ltd. DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS
CA2322136A1 (en) * 1998-03-06 1999-09-10 Ludo Edmond Josephine Kennis Glycine transport inhibitors
KR101315751B1 (ko) * 2011-05-30 2013-10-10 주식회사 엔지켐생명과학 로페라미드 옥사이드 모노하이드레이트의 신규한 제조방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3714159A (en) * 1971-03-30 1973-01-30 Janssen Pharmaceutica Nv 2,2-diaryl-4-(4'-aryl-4'-hydroxy-piper-idino)-butyramides
US4002618A (en) * 1976-02-23 1977-01-11 G. D. Searle & Co. 2,2-Diphenyl-5-(4-substituted-piperidino)-3-trans-pentenenitriles

Also Published As

Publication number Publication date
DE3671442D1 (de) 1990-06-28
ZA867713B (en) 1988-05-25
DK173954B1 (da) 2002-03-04
NO168640C (no) 1992-03-18
TNSN86138A1 (fr) 1990-01-01
NL950025I2 (nl) 1997-03-03
ATE53022T1 (de) 1990-06-15
DK486886A (da) 1987-04-12
HK52491A (en) 1991-07-19
DZ997A1 (fr) 2004-09-13
AU6381586A (en) 1987-04-16
IE59519B1 (en) 1994-03-09
CA1332236C (en) 1994-10-04
FI83642B (fi) 1991-04-30
IE862677L (en) 1987-04-11
EP0219898B1 (en) 1990-05-23
LV5767B4 (lv) 1997-06-20
CN86106848A (zh) 1987-04-08
HUT42444A (en) 1987-07-28
FI864099A (fi) 1987-04-12
LT2086B (lt) 1993-07-15
NL950025I1 (xx) 1996-01-02
GR862493B (en) 1987-02-03
LV5042A3 (lv) 1993-06-10
KR940001772B1 (ko) 1994-03-05
JPS6287569A (ja) 1987-04-22
NO864045L (no) 1987-04-13
NO1996010I1 (no) 1996-08-06
IL80268A0 (en) 1987-01-30
FI83642C (fi) 1991-08-12
SG46291G (en) 1991-07-26
FI864099A0 (fi) 1986-10-10
NZ217818A (en) 1989-03-29
DK486886D0 (da) 1986-10-10
NO864045D0 (no) 1986-10-10
EP0219898A1 (en) 1987-04-29
KR870003986A (ko) 1987-05-06
PT83506B (pt) 1989-02-28
ES2002001A6 (es) 1988-07-01
BG61320B2 (bg) 1997-05-30
ZM9486A1 (en) 1988-04-29
PT83506A (en) 1986-11-01
ZW20386A1 (en) 1988-05-11
JPH0517909B2 (xx) 1993-03-10
LV5767A4 (lv) 1996-12-20
PH22510A (en) 1988-09-12
NO168640B (no) 1991-12-09
SU1443798A3 (ru) 1988-12-07
CY1603A (en) 1992-04-03
CN1015453B (zh) 1992-02-12
EG18126A (en) 1992-08-30
AU583429B2 (en) 1989-04-27
HU196180B (en) 1988-10-28

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Legal Events

Date Code Title Description
KB Patent renewed
EXP Patent expired