FI864099A0 - Nya , -diaryl-4-aryl-4-hydroxi-1 -piperidin-butanamid-n-oxider. - Google Patents

Nya , -diaryl-4-aryl-4-hydroxi-1 -piperidin-butanamid-n-oxider.

Info

Publication number
FI864099A0
FI864099A0 FI864099A FI864099A FI864099A0 FI 864099 A0 FI864099 A0 FI 864099A0 FI 864099 A FI864099 A FI 864099A FI 864099 A FI864099 A FI 864099A FI 864099 A0 FI864099 A0 FI 864099A0
Authority
FI
Finland
Prior art keywords
6alkyl
compounds
diaryl
aryl
phenyl
Prior art date
Application number
FI864099A
Other languages
English (en)
Other versions
FI864099A (fi
FI83642C (fi
FI83642B (fi
Inventor
Lourens Wals
Ludwig Paul Cooymans
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of FI864099A0 publication Critical patent/FI864099A0/fi
Publication of FI864099A publication Critical patent/FI864099A/fi
Application granted granted Critical
Publication of FI83642B publication Critical patent/FI83642B/fi
Publication of FI83642C publication Critical patent/FI83642C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12Antidiarrhoeals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/92Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with a hetero atom directly attached to the ring nitrogen atom
    • C07D211/94Oxygen atom, e.g. piperidine N-oxide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Compositions Of Oxide Ceramics (AREA)
  • Electric Double-Layer Capacitors Or The Like (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
FI864099A 1985-10-11 1986-10-10 Foerfarande foer framstaellning av terapeutiskt anvaendbar , -difenyl-4-aryl-4-hydroxi-1 -piperidin-butanamid-n-oxid. FI83642C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US78656685A 1985-10-11 1985-10-11
US78656685 1985-10-11

Publications (4)

Publication Number Publication Date
FI864099A0 true FI864099A0 (fi) 1986-10-10
FI864099A FI864099A (fi) 1987-04-12
FI83642B FI83642B (fi) 1991-04-30
FI83642C FI83642C (fi) 1991-08-12

Family

ID=25138953

Family Applications (1)

Application Number Title Priority Date Filing Date
FI864099A FI83642C (fi) 1985-10-11 1986-10-10 Foerfarande foer framstaellning av terapeutiskt anvaendbar , -difenyl-4-aryl-4-hydroxi-1 -piperidin-butanamid-n-oxid.

Country Status (33)

Country Link
EP (1) EP0219898B1 (fi)
JP (1) JPS6287569A (fi)
KR (1) KR940001772B1 (fi)
CN (1) CN1015453B (fi)
AT (1) ATE53022T1 (fi)
AU (1) AU583429B2 (fi)
BG (1) BG61320B2 (fi)
CA (1) CA1332236C (fi)
CY (1) CY1603A (fi)
DE (1) DE3671442D1 (fi)
DK (1) DK173954B1 (fi)
DZ (1) DZ997A1 (fi)
EG (1) EG18126A (fi)
ES (1) ES2002001A6 (fi)
FI (1) FI83642C (fi)
GR (1) GR862493B (fi)
HK (1) HK52491A (fi)
HU (1) HU196180B (fi)
IE (1) IE59519B1 (fi)
IL (1) IL80268A (fi)
LT (1) LT2086B (fi)
LV (2) LV5042A3 (fi)
NL (1) NL950025I2 (fi)
NO (2) NO168640C (fi)
NZ (1) NZ217818A (fi)
PH (1) PH22510A (fi)
PT (1) PT83506B (fi)
SG (1) SG46291G (fi)
SU (1) SU1443798A3 (fi)
TN (1) TNSN86138A1 (fi)
ZA (1) ZA867713B (fi)
ZM (1) ZM9486A1 (fi)
ZW (1) ZW20386A1 (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2088273C (en) * 1990-08-09 1996-05-14 Daniel Louis Barone Processes for formulating a solid oral dosage form of loperamide compounds
US5434158A (en) * 1994-04-26 1995-07-18 Merck & Co., Inc. Spiro-substituted azacycles as neurokinin-3 antagonists
WO1997024325A1 (en) * 1995-12-28 1997-07-10 Takeda Chemical Industries, Ltd. DIPHENYLMETHANE DERIVATIVES AS MIP-1α/RANTES RECEPTOR ANTAGONISTS
AU3254499A (en) * 1998-03-06 1999-09-20 Janssen Pharmaceutica N.V. Glycine transport inhibitors
KR101315751B1 (ko) * 2011-05-30 2013-10-10 주식회사 엔지켐생명과학 로페라미드 옥사이드 모노하이드레이트의 신규한 제조방법

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3714159A (en) * 1971-03-30 1973-01-30 Janssen Pharmaceutica Nv 2,2-diaryl-4-(4'-aryl-4'-hydroxy-piper-idino)-butyramides
US4002618A (en) * 1976-02-23 1977-01-11 G. D. Searle & Co. 2,2-Diphenyl-5-(4-substituted-piperidino)-3-trans-pentenenitriles

Also Published As

Publication number Publication date
SG46291G (en) 1991-07-26
FI864099A (fi) 1987-04-12
EP0219898B1 (en) 1990-05-23
KR940001772B1 (ko) 1994-03-05
IE862677L (en) 1987-04-11
HU196180B (en) 1988-10-28
IE59519B1 (en) 1994-03-09
ZA867713B (en) 1988-05-25
NO1996010I1 (no) 1996-08-06
ZM9486A1 (en) 1988-04-29
ZW20386A1 (en) 1988-05-11
KR870003986A (ko) 1987-05-06
PT83506A (en) 1986-11-01
FI83642C (fi) 1991-08-12
EG18126A (en) 1992-08-30
LV5042A3 (lv) 1993-06-10
LT2086B (lt) 1993-07-15
JPS6287569A (ja) 1987-04-22
DK173954B1 (da) 2002-03-04
NZ217818A (en) 1989-03-29
DE3671442D1 (de) 1990-06-28
IL80268A0 (en) 1987-01-30
DZ997A1 (fr) 2004-09-13
CA1332236C (en) 1994-10-04
CY1603A (en) 1992-04-03
SU1443798A3 (ru) 1988-12-07
NO168640C (no) 1992-03-18
DK486886A (da) 1987-04-12
ATE53022T1 (de) 1990-06-15
PH22510A (en) 1988-09-12
HUT42444A (en) 1987-07-28
DK486886D0 (da) 1986-10-10
GR862493B (en) 1987-02-03
NL950025I2 (nl) 1997-03-03
ES2002001A6 (es) 1988-07-01
PT83506B (pt) 1989-02-28
AU6381586A (en) 1987-04-16
LV5767B4 (lv) 1997-06-20
HK52491A (en) 1991-07-19
AU583429B2 (en) 1989-04-27
FI83642B (fi) 1991-04-30
EP0219898A1 (en) 1987-04-29
TNSN86138A1 (fr) 1990-01-01
NO168640B (no) 1991-12-09
JPH0517909B2 (fi) 1993-03-10
NO864045D0 (no) 1986-10-10
BG61320B2 (bg) 1997-05-30
NL950025I1 (fi) 1996-01-02
CN86106848A (zh) 1987-04-08
IL80268A (en) 1991-03-10
CN1015453B (zh) 1992-02-12
LV5767A4 (lv) 1996-12-20
NO864045L (no) 1987-04-13

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Legal Events

Date Code Title Description
ND Supplementary protection certificate (spc) granted
SPCG Supplementary protection certificate granted

Spc suppl protection certif: L88

Extension date: 20090603

FG Patent granted

Owner name: JANSSEN PHARMACEUTICA N.V.

MA Patent expired