KR20210008008A - 항-msr1 항체 및 이의 사용 방법 - Google Patents

항-msr1 항체 및 이의 사용 방법 Download PDF

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KR20210008008A
KR20210008008A KR1020207034456A KR20207034456A KR20210008008A KR 20210008008 A KR20210008008 A KR 20210008008A KR 1020207034456 A KR1020207034456 A KR 1020207034456A KR 20207034456 A KR20207034456 A KR 20207034456A KR 20210008008 A KR20210008008 A KR 20210008008A
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South Korea
Prior art keywords
antibody
formula
alkyl
msr1
antigen
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KR1020207034456A
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Korean (ko)
Inventor
크리스토스 키랏수스
토마스 니톨리
안나 줌스텍
제스퍼 그로마다
빅토리아 구사로바
에이미 한
소콜 하시나스토
앤드류 제이. 머피
윌리엄 올슨
매튜 슬리만
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리제너론 파마슈티칼스 인코포레이티드
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Publication of KR20210008008A publication Critical patent/KR20210008008A/ko
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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    • A61K31/165Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
    • A61K31/167Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • A61K47/68Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
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    • A61K47/6889Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
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    • C07K2317/30Immunoglobulins specific features characterized by aspects of specificity or valency
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  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
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  • Diabetes (AREA)
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  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
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  • Physical Education & Sports Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
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KR1020207034456A 2018-05-09 2019-05-08 항-msr1 항체 및 이의 사용 방법 Ceased KR20210008008A (ko)

Applications Claiming Priority (11)

Application Number Priority Date Filing Date Title
US201862669276P 2018-05-09 2018-05-09
US62/669,276 2018-05-09
US201862678200P 2018-05-30 2018-05-30
US62/678,200 2018-05-30
US201862769946P 2018-11-20 2018-11-20
US62/769,946 2018-11-20
US201962789987P 2019-01-08 2019-01-08
US62/789,987 2019-01-08
US201962821362P 2019-03-20 2019-03-20
US62/821,362 2019-03-20
PCT/US2019/031383 WO2019217591A1 (en) 2018-05-09 2019-05-08 Anti-msr1 antibodies and methods of use thereof

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KR20210008008A true KR20210008008A (ko) 2021-01-20

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KR1020207034456A Ceased KR20210008008A (ko) 2018-05-09 2019-05-08 항-msr1 항체 및 이의 사용 방법

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US (2) US11377502B2 (enExample)
EP (1) EP3790899A1 (enExample)
JP (2) JP7590871B2 (enExample)
KR (1) KR20210008008A (enExample)
CN (2) CN118955710A (enExample)
AU (1) AU2019265703A1 (enExample)
BR (1) BR112020022400A2 (enExample)
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