CN118955710A - 抗msr1抗体及其使用方法 - Google Patents

抗msr1抗体及其使用方法 Download PDF

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Publication number
CN118955710A
CN118955710A CN202410707876.3A CN202410707876A CN118955710A CN 118955710 A CN118955710 A CN 118955710A CN 202410707876 A CN202410707876 A CN 202410707876A CN 118955710 A CN118955710 A CN 118955710A
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China
Prior art keywords
antibody
group
seq
alkyl
formula
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Pending
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CN202410707876.3A
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Chinese (zh)
Inventor
C·凯拉特索斯
T·尼托利
A·祖姆斯蒂格
J·格罗玛达
V·古萨罗娃
A·韩
S·哈桑纳斯托
A·J·墨菲
W·奥尔松
M·思利曼
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Regeneron Pharmaceuticals Inc
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Regeneron Pharmaceuticals Inc
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Publication of CN118955710A publication Critical patent/CN118955710A/zh
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
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    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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    • A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
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    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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    • C07K2317/77—Internalization into the cell
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    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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  • Health & Medical Sciences (AREA)
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  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Diabetes (AREA)
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CN202410707876.3A 2018-05-09 2019-05-08 抗msr1抗体及其使用方法 Pending CN118955710A (zh)

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
US201862669276P 2018-05-09 2018-05-09
US62/669276 2018-05-09
US201862678200P 2018-05-30 2018-05-30
US62/678200 2018-05-30
US201862769946P 2018-11-20 2018-11-20
US62/769946 2018-11-20
US201962789987P 2019-01-08 2019-01-08
US62/789987 2019-01-08
US201962821362P 2019-03-20 2019-03-20
US62/821362 2019-03-20
PCT/US2019/031383 WO2019217591A1 (en) 2018-05-09 2019-05-08 Anti-msr1 antibodies and methods of use thereof
CN201980046191.6A CN112533951A (zh) 2018-05-09 2019-05-08 抗msr1抗体及其使用方法

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CN118955710A true CN118955710A (zh) 2024-11-15

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CN201980046191.6A Pending CN112533951A (zh) 2018-05-09 2019-05-08 抗msr1抗体及其使用方法

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