KR20160070165A - Fc 리간드 친화성이 감소된 항-IFNAR1 항체 - Google Patents

Fc 리간드 친화성이 감소된 항-IFNAR1 항체 Download PDF

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KR20160070165A
KR20160070165A KR1020167014946A KR20167014946A KR20160070165A KR 20160070165 A KR20160070165 A KR 20160070165A KR 1020167014946 A KR1020167014946 A KR 1020167014946A KR 20167014946 A KR20167014946 A KR 20167014946A KR 20160070165 A KR20160070165 A KR 20160070165A
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antibody
seq
disease
antibodies
chain variable
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Korean (ko)
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안토니 코일
피터 키너
헤렌 우
리카르도 시보티
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메디뮨 엘엘씨
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    • C07ORGANIC CHEMISTRY
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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • A01K2227/105Murine
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    • C07K2299/00Coordinates from 3D structures of peptides, e.g. proteins or enzymes
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    • C07ORGANIC CHEMISTRY
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    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/71Decreased effector function due to an Fc-modification
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    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/732Antibody-dependent cellular cytotoxicity [ADCC]
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    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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KR1020167014946A 2008-02-08 2009-02-06 Fc 리간드 친화성이 감소된 항-IFNAR1 항체 Ceased KR20160070165A (ko)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US696208P 2008-02-08 2008-02-08
US61/006,962 2008-02-08
US3461808P 2008-03-07 2008-03-07
US61/034,618 2008-03-07
US4997008P 2008-05-02 2008-05-02
US61/049,970 2008-05-02
PCT/US2009/033358 WO2009100309A2 (en) 2008-02-08 2009-02-06 Anti-ifnar1 antibodies with reduced fc ligand affinity

Related Parent Applications (1)

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KR1020107019995A Division KR101666229B1 (ko) 2008-02-08 2009-02-06 Fc 리간드 친화성이 감소된 항-IFNAR1 항체

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KR20160070165A true KR20160070165A (ko) 2016-06-17

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KR1020167014946A Ceased KR20160070165A (ko) 2008-02-08 2009-02-06 Fc 리간드 친화성이 감소된 항-IFNAR1 항체
KR1020107019995A Active KR101666229B1 (ko) 2008-02-08 2009-02-06 Fc 리간드 친화성이 감소된 항-IFNAR1 항체

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KR1020107019995A Active KR101666229B1 (ko) 2008-02-08 2009-02-06 Fc 리간드 친화성이 감소된 항-IFNAR1 항체

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US (6) US20110059078A1 (enExample)
EP (1) EP2250279B1 (enExample)
JP (1) JP5608100B2 (enExample)
KR (2) KR20160070165A (enExample)
CN (1) CN101952454B (enExample)
AU (1) AU2009212273B2 (enExample)
BR (2) BRPI0907735B1 (enExample)
CA (1) CA2713981C (enExample)
CY (1) CY1117827T1 (enExample)
DK (1) DK2250279T3 (enExample)
ES (1) ES2581917T3 (enExample)
FI (1) FIC20220024I1 (enExample)
FR (1) FR22C1019I2 (enExample)
HR (1) HRP20160855T1 (enExample)
HU (3) HUE028958T2 (enExample)
LT (1) LTC2250279I2 (enExample)
LU (1) LUC00263I2 (enExample)
MX (1) MX2010008578A (enExample)
NL (1) NL301175I2 (enExample)
NO (1) NO2022016I1 (enExample)
PL (1) PL2250279T3 (enExample)
PT (1) PT2250279E (enExample)
SG (1) SG188129A1 (enExample)
SI (1) SI2250279T1 (enExample)
WO (1) WO2009100309A2 (enExample)

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CY1117827T1 (el) 2017-05-17
EP2250279A4 (en) 2011-03-30
PL2250279T3 (pl) 2016-11-30
CN101952454A (zh) 2011-01-19
JP5608100B2 (ja) 2014-10-15
HUS2200023I1 (hu) 2022-06-28
HK1149297A1 (en) 2011-09-30
BRPI0907735B1 (pt) 2021-10-05

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