ES2581917T3 - Anticuerpos anti-IFNAR1 con afinidad de ligando de Fc reducida - Google Patents
Anticuerpos anti-IFNAR1 con afinidad de ligando de Fc reducida Download PDFInfo
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- ES2581917T3 ES2581917T3 ES09707396.9T ES09707396T ES2581917T3 ES 2581917 T3 ES2581917 T3 ES 2581917T3 ES 09707396 T ES09707396 T ES 09707396T ES 2581917 T3 ES2581917 T3 ES 2581917T3
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Landscapes
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| US49970P | 2008-05-02 | ||
| PCT/US2009/033358 WO2009100309A2 (en) | 2008-02-08 | 2009-02-06 | Anti-ifnar1 antibodies with reduced fc ligand affinity |
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| ES2581917T3 true ES2581917T3 (es) | 2016-09-08 |
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| RU2412202C2 (ru) * | 2004-06-21 | 2011-02-20 | Медарекс, Инк. | Антитела рецептора 1 интерферона альфа и их применение |
| EP3050963B1 (en) | 2005-03-31 | 2019-09-18 | Chugai Seiyaku Kabushiki Kaisha | Process for production of polypeptide by regulation of assembly |
| IN2014DN10515A (enExample) | 2006-03-31 | 2015-08-21 | Chugai Pharmaceutical Co Ltd | |
| ES2654040T3 (es) | 2006-03-31 | 2018-02-12 | Chugai Seiyaku Kabushiki Kaisha | Método de modificación de anticuerpos para la purificación de anticuerpos biespecíficos |
| ES2687808T3 (es) | 2007-09-26 | 2018-10-29 | Chugai Seiyaku Kabushiki Kaisha | Región constante de anticuerpo modificado |
| MX369784B (es) | 2007-09-26 | 2019-11-21 | Chugai Pharmaceutical Co Ltd | Metodo de modificacion del punto isoelectrico de anticuerpos mediante la sustitucion de aminoacidos en region de determinacion de complementariedad (cdr). |
| KR20160074019A (ko) | 2007-12-05 | 2016-06-27 | 추가이 세이야쿠 가부시키가이샤 | 항ｎｒ１０ 항체 및 그의 이용 |
| HRP20160855T1 (hr) * | 2008-02-08 | 2016-09-23 | Medimmune, Llc | Anti-ifnar1 protutijela sa smanjenim afinitetom fc liganda |
| TWI440469B (zh) | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
| JP5717624B2 (ja) | 2009-03-19 | 2015-05-13 | 中外製薬株式会社 | 抗体定常領域改変体 |
| US20120071634A1 (en) | 2009-03-19 | 2012-03-22 | Chugai Seiyaku Kabushiki Kaisha | Antibody Constant Region Variant |
| PE20120562A1 (es) | 2009-05-15 | 2012-06-06 | Chugai Pharmaceutical Co Ltd | Anticuerpo anti-axl |
| JP5837821B2 (ja) | 2009-09-24 | 2015-12-24 | 中外製薬株式会社 | 抗体定常領域改変体 |
| ES2609043T3 (es) * | 2009-11-30 | 2017-04-18 | Janssen Biotech, Inc. | Anticuerpos mutantes Fc con funciones de efecto abladas |
| US10053513B2 (en) | 2009-11-30 | 2018-08-21 | Janssen Biotech, Inc. | Antibody Fc mutants with ablated effector functions |
| WO2011108714A1 (ja) | 2010-03-04 | 2011-09-09 | 中外製薬株式会社 | 抗体定常領域改変体 |
| ES2720136T3 (es) * | 2010-12-22 | 2019-07-18 | Teva Pharmaceuticals Australia Pty Ltd | Anticuerpo modificado con semivida mejorada |
| WO2012130831A1 (en) | 2011-03-29 | 2012-10-04 | Roche Glycart Ag | Antibody fc variants |
| US9428560B2 (en) * | 2011-06-21 | 2016-08-30 | Kyowa Hakko Kirin Co., Ltd | Protein comprising truncated form of extracellular region protein of Frizzled 2, and pharmaceutical composition for treating bone diseases which comprises said protein |
| RU2014120375A (ru) * | 2011-11-01 | 2015-12-10 | Рош Гликарт Аг | Модель антителозависимой клеточной цитотоксичности в живом организме |
| KR102320059B1 (ko) * | 2012-06-13 | 2021-11-01 | 아스트라제네카 아베 | 항-i형 인터페론 수용체(ifnar) 항체에 대한 고정 투여 계획 |
| TW201402611A (zh) | 2012-06-21 | 2014-01-16 | Univ Indiana Res & Tech Corp | 具有改變之ｆｃ效應子功能之腸促胰島素受體配體多肽ｆｃ區融合多肽及結合物 |
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