KR20110028665A - 세린 프로테아제, 특히 c형 간염 바이러스 ns3-ns4 프로테아제의 억제제 - Google Patents
세린 프로테아제, 특히 c형 간염 바이러스 ns3-ns4 프로테아제의 억제제 Download PDFInfo
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- KR20110028665A KR20110028665A KR1020117004808A KR20117004808A KR20110028665A KR 20110028665 A KR20110028665 A KR 20110028665A KR 1020117004808 A KR1020117004808 A KR 1020117004808A KR 20117004808 A KR20117004808 A KR 20117004808A KR 20110028665 A KR20110028665 A KR 20110028665A
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- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
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- A61P31/12—Antivirals
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- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
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- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
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- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06008—Dipeptides with the first amino acid being neutral
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/10—Tetrapeptides
- C07K5/1027—Tetrapeptides containing heteroatoms different from O, S, or N
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- Proteomics, Peptides & Aminoacids (AREA)
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- Oncology (AREA)
- Communicable Diseases (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37184602P | 2002-04-11 | 2002-04-11 | |
US60/371,846 | 2002-04-11 |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR10-2004-7016168A Division KR20040099425A (ko) | 2002-04-11 | 2003-04-11 | 세린 프로테아제, 특히 c형 간염 바이러스 ns3-ns4프로테아제의 억제제 |
Publications (1)
Publication Number | Publication Date |
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KR20110028665A true KR20110028665A (ko) | 2011-03-21 |
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Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
KR10-2004-7016168A KR20040099425A (ko) | 2002-04-11 | 2003-04-11 | 세린 프로테아제, 특히 c형 간염 바이러스 ns3-ns4프로테아제의 억제제 |
KR1020117004808A KR20110028665A (ko) | 2002-04-11 | 2003-04-11 | 세린 프로테아제, 특히 c형 간염 바이러스 ns3-ns4 프로테아제의 억제제 |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
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KR10-2004-7016168A KR20040099425A (ko) | 2002-04-11 | 2003-04-11 | 세린 프로테아제, 특히 c형 간염 바이러스 ns3-ns4프로테아제의 억제제 |
Country Status (18)
Families Citing this family (120)
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WO2003087092A3 (en) | 2004-09-10 |
JP2010241821A (ja) | 2010-10-28 |
EP2468744A2 (en) | 2012-06-27 |
CA2481369C (en) | 2012-07-10 |
MXPA04009938A (es) | 2004-12-13 |
KR20040099425A (ko) | 2004-11-26 |
AU2009233604A1 (en) | 2009-11-26 |
TW200403236A (en) | 2004-03-01 |
HK1081196A1 (en) | 2006-05-12 |
US20100173851A1 (en) | 2010-07-08 |
US20070292933A1 (en) | 2007-12-20 |
EP1497282A2 (en) | 2005-01-19 |
CN1649864A (zh) | 2005-08-03 |
US20040018986A1 (en) | 2004-01-29 |
PL373399A1 (en) | 2005-08-22 |
NZ561851A (en) | 2009-05-31 |
CN101245097A (zh) | 2008-08-20 |
CA2481369A1 (en) | 2003-10-23 |
NZ575692A (en) | 2009-10-30 |
AU2003223602B2 (en) | 2010-05-13 |
RU2004133044A (ru) | 2006-01-27 |
WO2003087092A2 (en) | 2003-10-23 |
NO20044889L (no) | 2005-01-10 |
AU2003223602B8 (en) | 2010-05-27 |
JP2005535574A (ja) | 2005-11-24 |
JP2009185081A (ja) | 2009-08-20 |
CN100381440C (zh) | 2008-04-16 |
IL164455A0 (en) | 2005-12-18 |
NO20110773L (no) | 2005-01-10 |
SG159385A1 (en) | 2010-03-30 |
ZA200408243B (en) | 2006-07-26 |
AU2003223602A1 (en) | 2003-10-27 |
US7273885B2 (en) | 2007-09-25 |
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