KR20090086121A - 용매화 일라프라졸의 결정형 - Google Patents

용매화 일라프라졸의 결정형 Download PDF

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Publication number
KR20090086121A
KR20090086121A KR1020097013491A KR20097013491A KR20090086121A KR 20090086121 A KR20090086121 A KR 20090086121A KR 1020097013491 A KR1020097013491 A KR 1020097013491A KR 20097013491 A KR20097013491 A KR 20097013491A KR 20090086121 A KR20090086121 A KR 20090086121A
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KR
South Korea
Prior art keywords
crystalline
ilaprazole
burglar
location
racemic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
KR1020097013491A
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English (en)
Korean (ko)
Inventor
존 엠. 브랙켓
데이비드 티. 조나이티스
웨이 라이
스테판 디. 파렌트
Original Assignee
일양약품주식회사
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39313094&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20090086121(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 일양약품주식회사 filed Critical 일양약품주식회사
Publication of KR20090086121A publication Critical patent/KR20090086121A/ko
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
KR1020097013491A 2006-12-29 2007-12-28 용매화 일라프라졸의 결정형 Ceased KR20090086121A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US87760806P 2006-12-29 2006-12-29
US60/877,608 2006-12-29
US88749907P 2007-01-31 2007-01-31
US60/887,499 2007-01-31

Publications (1)

Publication Number Publication Date
KR20090086121A true KR20090086121A (ko) 2009-08-10

Family

ID=39313094

Family Applications (3)

Application Number Title Priority Date Filing Date
KR1020097013491A Ceased KR20090086121A (ko) 2006-12-29 2007-12-28 용매화 일라프라졸의 결정형
KR1020117016139A Withdrawn KR20110091594A (ko) 2006-12-29 2007-12-28 라세믹 일라프라졸의 고체상 형태
KR1020097013519A Active KR101052387B1 (ko) 2006-12-29 2007-12-28 라세믹 일라프라졸의 고체상 형태

Family Applications After (2)

Application Number Title Priority Date Filing Date
KR1020117016139A Withdrawn KR20110091594A (ko) 2006-12-29 2007-12-28 라세믹 일라프라졸의 고체상 형태
KR1020097013519A Active KR101052387B1 (ko) 2006-12-29 2007-12-28 라세믹 일라프라졸의 고체상 형태

Country Status (18)

Country Link
US (4) US7989632B2 (https=)
EP (2) EP2102192B1 (https=)
JP (2) JP5315254B2 (https=)
KR (3) KR20090086121A (https=)
CN (2) CN101687848B (https=)
AU (2) AU2007341984B2 (https=)
CA (2) CA2674347C (https=)
DK (1) DK2102192T3 (https=)
ES (1) ES2398846T3 (https=)
IL (2) IL199242A (https=)
MX (2) MX2009006529A (https=)
MY (2) MY145936A (https=)
NO (2) NO20092398L (https=)
NZ (2) NZ577129A (https=)
PL (1) PL2102192T3 (https=)
PT (1) PT2102192E (https=)
RU (2) RU2466129C2 (https=)
WO (2) WO2008083333A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011071314A3 (en) * 2009-12-08 2011-11-10 Il-Yang Pharm. Co., Ltd. Processes for preparing crystalline forms a and b of ilaprazole and process for converting the crystalline forms
KR102250509B1 (ko) 2020-12-09 2021-05-11 유니셀랩 주식회사 새로운 일라프라졸/자일리톨 공결정

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103204842B (zh) * 2012-01-13 2014-10-15 丽珠医药集团股份有限公司 结晶型艾普拉唑钠水合物及其制备方法
CN103204843B (zh) * 2012-01-13 2014-12-31 丽珠医药集团股份有限公司 结晶型艾普拉唑钠乙醇化物及其制备方法
WO2013114232A1 (en) * 2012-02-02 2013-08-08 Lupin Limited Process for preparation of crystalline form l of ilaprazole
CN102746277B (zh) * 2012-06-21 2014-05-14 丽珠医药集团股份有限公司 一种结晶形式的艾普拉唑钠及其制备方法
CN102746275B (zh) * 2012-06-21 2014-07-16 丽珠医药集团股份有限公司 结晶型艾普拉唑钠及其制备方法
CN103172618B (zh) * 2013-02-27 2014-09-03 丽珠医药集团股份有限公司 艾普拉唑晶型及其制备方法
CN104370886B (zh) * 2014-11-18 2016-05-18 宁夏康亚药业有限公司 艾普拉唑晶型及其制备方法和应用
CN105055342A (zh) * 2015-08-13 2015-11-18 青岛蓝盛洋医药生物科技有限责任公司 一种治疗消化性溃疡的药物艾普拉唑钠组合物冻干粉针剂
CN105055343A (zh) * 2015-08-31 2015-11-18 青岛蓝盛洋医药生物科技有限责任公司 一种治疗胃病的药物艾普拉唑钠组合物冻干粉针剂
CN106749191A (zh) * 2016-12-10 2017-05-31 珠海保税区丽珠合成制药有限公司 艾普拉唑晶型ⅱ及其制备方法
KR101961028B1 (ko) * 2017-10-12 2019-03-21 중앙대학교 산학협력단 일라프라졸을 유효성분으로 함유하는 급성 위염의 예방 또는 치료용 약학 조성물
KR102332996B1 (ko) * 2020-04-13 2021-12-01 중앙대학교 산학협력단 일라프라졸을 유효성분으로 함유하는 장폐색증 예방 또는 치료용 약학조성물
KR20220065235A (ko) 2020-11-13 2022-05-20 주식회사 파마코스텍 일라프라졸 혼형 결정의 신규한 제조방법
KR20210019469A (ko) 2021-02-02 2021-02-22 주식회사 파마코스텍 일라프라졸 나트륨 결정형 및 신규한 제조방법
CN117050060A (zh) * 2023-07-20 2023-11-14 浙江美诺华药物化学有限公司 一种艾普拉唑晶型f的制备方法
KR20250156870A (ko) 2024-04-25 2025-11-04 엠에프씨 주식회사 일라프라졸 마그네슘염 수화물의 제조방법
CN119462610A (zh) * 2024-11-06 2025-02-18 甘肃皓天科技股份有限公司 一种艾普拉唑新晶型及其制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0179401B1 (ko) 1994-02-28 1999-03-20 송택선 신규한 5-피롤릴-2-피리딜메틸설피닐벤즈이미다졸 유도체
US6331539B1 (en) 1999-06-10 2001-12-18 3M Innovative Properties Company Sulfonamide and sulfamide substituted imidazoquinolines
RU2232159C2 (ru) * 1999-07-29 2004-07-10 Регентский Совет Университета Калифорнии Производные бензимидазола и фармацевтические композиции, содержащие пролекарство ингибитора протонного насоса
US6627646B2 (en) * 2001-07-17 2003-09-30 Sepracor Inc. Norastemizole polymorphs
PL373539A1 (en) 2002-03-27 2005-09-05 Teva Pharmaceutical Industries Ltd. Lansoprazole polymorphs and processes for preparation thereof
WO2006099810A1 (en) 2005-03-25 2006-09-28 Livzon Pharmaceutical Group Inc. Substituted sulfoxide compounds, methods for preparing the same and use thereof
WO2006118534A1 (en) 2005-05-04 2006-11-09 Astrazeneca Ab Proton pump inhibitors in the treatment of sleep disturbance due to silent gastro-esophageal reflux

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011071314A3 (en) * 2009-12-08 2011-11-10 Il-Yang Pharm. Co., Ltd. Processes for preparing crystalline forms a and b of ilaprazole and process for converting the crystalline forms
EA019058B1 (ru) * 2009-12-08 2013-12-30 Ил-Янг Фармасьютикал Компани Лтд. Способ получения кристаллических форм а и в илапразола и способ превращения указанных кристаллических форм
KR102250509B1 (ko) 2020-12-09 2021-05-11 유니셀랩 주식회사 새로운 일라프라졸/자일리톨 공결정

Also Published As

Publication number Publication date
NO20092464L (no) 2009-09-28
NZ577509A (en) 2012-01-12
JP5315254B2 (ja) 2013-10-16
IL199242A (en) 2013-10-31
US20080200516A1 (en) 2008-08-21
CN101687848A (zh) 2010-03-31
US7999110B2 (en) 2011-08-16
WO2008083341A1 (en) 2008-07-10
HK1140483A1 (en) 2010-10-15
PL2102192T3 (pl) 2013-04-30
MY146462A (en) 2012-08-15
KR20110091594A (ko) 2011-08-11
NO342530B1 (no) 2018-06-11
DK2102192T3 (da) 2013-03-04
NZ577129A (en) 2012-02-24
US20080200517A1 (en) 2008-08-21
EP2102191A1 (en) 2009-09-23
RU2009122241A (ru) 2011-02-10
CA2674347C (en) 2013-08-06
MX2009006530A (es) 2009-08-18
JP2010514807A (ja) 2010-05-06
AU2007341992B2 (en) 2012-07-05
NO20092398L (no) 2009-09-28
IL199234A (en) 2013-07-31
JP2010514806A (ja) 2010-05-06
EP2102191B1 (en) 2012-11-21
HK1140484A1 (en) 2010-10-15
CN101687848B (zh) 2013-05-15
ES2398846T3 (es) 2013-03-22
RU2464270C2 (ru) 2012-10-20
CN101687849A (zh) 2010-03-31
PT2102192E (pt) 2013-01-23
KR101052387B1 (ko) 2011-07-28
EP2102192A1 (en) 2009-09-23
KR20090086615A (ko) 2009-08-13
CA2674347A1 (en) 2008-07-10
CN101687849B (zh) 2013-05-29
US20110082174A1 (en) 2011-04-07
CA2674358A1 (en) 2008-07-10
AU2007341984A1 (en) 2008-07-10
RU2466129C2 (ru) 2012-11-10
WO2008083333A1 (en) 2008-07-10
US8592600B2 (en) 2013-11-26
EP2102192B1 (en) 2012-11-14
MX2009006529A (es) 2009-08-18
JP5315253B2 (ja) 2013-10-16
MY145936A (en) 2012-05-31
AU2007341984B2 (en) 2012-07-05
CA2674358C (en) 2013-10-08
US7989632B2 (en) 2011-08-02
RU2009122242A (ru) 2011-02-10
AU2007341992A1 (en) 2008-07-10
US8592599B2 (en) 2013-11-26
US20110046184A1 (en) 2011-02-24

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