KR20090084880A - 글루코키나제(ｇｌｋ) 활성인자로서 벤조일 아미노 복소환 화합물 - Google Patents

글루코키나제(ｇｌｋ) 활성인자로서 벤조일 아미노 복소환 화합물 Download PDF

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KR20090084880A
KR20090084880A KR1020097010497A KR20097010497A KR20090084880A KR 20090084880 A KR20090084880 A KR 20090084880A KR 1020097010497 A KR1020097010497 A KR 1020097010497A KR 20097010497 A KR20097010497 A KR 20097010497A KR 20090084880 A KR20090084880 A KR 20090084880A
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formula
compound
oxy
alkyl
propan
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Korean (ko)
Inventor
나타니엘 조지 마틴
대런 맥커레처
커트 고든 파이크
마이클 제임스 워링
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아스트라제네카 아베
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Application filed by 아스트라제네카 아베 filed Critical 아스트라제네카 아베
Publication of KR20090084880A publication Critical patent/KR20090084880A/ko
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
KR1020097010497A 2006-10-26 2007-10-25 글루코키나제(ｇｌｋ) 활성인자로서 벤조일 아미노 복소환 화합물 Withdrawn KR20090084880A (ko)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US86305606P 2006-10-26 2006-10-26
US60/863,056 2006-10-26
US95737007P 2007-08-22 2007-08-22
US60/957,370 2007-08-22

Publications (1)

Publication Number Publication Date
KR20090084880A true KR20090084880A (ko) 2009-08-05

Family

ID=38925536

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020097010497A Withdrawn KR20090084880A (ko) 2006-10-26 2007-10-25 글루코키나제(ｇｌｋ) 활성인자로서 벤조일 아미노 복소환 화합물

Country Status (20)

Country Link
US (2) US7671060B2 (OSRAM)
EP (2) EP2272834A1 (OSRAM)
JP (2) JP4673429B2 (OSRAM)
KR (1) KR20090084880A (OSRAM)
CN (1) CN101805299A (OSRAM)
AR (1) AR063393A1 (OSRAM)
AU (1) AU2007310624B2 (OSRAM)
BR (1) BRPI0718155A2 (OSRAM)
CA (1) CA2667316A1 (OSRAM)
CL (1) CL2007003061A1 (OSRAM)
CO (1) CO6160314A2 (OSRAM)
IL (1) IL198143A0 (OSRAM)
MX (1) MX2009004467A (OSRAM)
NO (1) NO20091596L (OSRAM)
PE (1) PE20080927A1 (OSRAM)
RU (1) RU2440992C2 (OSRAM)
SA (1) SA07280576B1 (OSRAM)
TW (1) TW200825060A (OSRAM)
UY (1) UY30659A1 (OSRAM)
WO (1) WO2008050117A1 (OSRAM)

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US20080318968A1 (en) 2008-12-25
US7671060B2 (en) 2010-03-02
UY30659A1 (es) 2008-05-31
SA07280576B1 (ar) 2011-06-22
PE20080927A1 (es) 2008-09-20
US7964725B2 (en) 2011-06-21
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AU2007310624A1 (en) 2008-05-02
RU2009114802A (ru) 2010-12-10
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NO20091596L (no) 2009-06-30
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RU2440992C2 (ru) 2012-01-27
IL198143A0 (en) 2009-12-24
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MX2009004467A (es) 2009-07-27
BRPI0718155A2 (pt) 2013-11-19
AU2007310624A8 (en) 2009-05-14
JP4673429B2 (ja) 2011-04-20
AR063393A1 (es) 2009-01-28
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