KR20060120069A - 피라졸로피리딘 및 그의 유사체 - Google Patents
피라졸로피리딘 및 그의 유사체 Download PDFInfo
- Publication number
- KR20060120069A KR20060120069A KR20067008540A KR20067008540A KR20060120069A KR 20060120069 A KR20060120069 A KR 20060120069A KR 20067008540 A KR20067008540 A KR 20067008540A KR 20067008540 A KR20067008540 A KR 20067008540A KR 20060120069 A KR20060120069 A KR 20060120069A
- Authority
- KR
- South Korea
- Prior art keywords
- group
- alkyl
- alkylenyl
- aryl
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 0 C[C@@](*)C*C(*)=C1C(/*=C/C(C)(C)/C=*(\C)/C2)=C2*=C(*)C1=* Chemical compound C[C@@](*)C*C(*)=C1C(/*=C/C(C)(C)/C=*(\C)/C2)=C2*=C(*)C1=* 0.000 description 14
- LFGYNRGLGTWPKF-UHFFFAOYSA-N CC(C)(Cc([n](CCOC)nc12)c1c1ccccc1nc2N)NC(C)=O Chemical compound CC(C)(Cc([n](CCOC)nc12)c1c1ccccc1nc2N)NC(C)=O LFGYNRGLGTWPKF-UHFFFAOYSA-N 0.000 description 1
- NUESVBZZKMCNIF-UHFFFAOYSA-N CC(C)(Cc([n](CCOC)nc12)c1c1ccccc1nc2N)NC(c1ccncc1)=O Chemical compound CC(C)(Cc([n](CCOC)nc12)c1c1ccccc1nc2N)NC(c1ccncc1)=O NUESVBZZKMCNIF-UHFFFAOYSA-N 0.000 description 1
- RQSVSLRXGWJXIU-UHFFFAOYSA-N CCC(C)C(C)CN(C)C Chemical compound CCC(C)C(C)CN(C)C RQSVSLRXGWJXIU-UHFFFAOYSA-N 0.000 description 1
- VKMITDROJPJEQG-APPJTMTASA-N CCCN/C(/CCCc1cc(-c2ccccc2)n[o]1)=C(/c1ccccc1N=C1N)\C1=N Chemical compound CCCN/C(/CCCc1cc(-c2ccccc2)n[o]1)=C(/c1ccccc1N=C1N)\C1=N VKMITDROJPJEQG-APPJTMTASA-N 0.000 description 1
- MIEAQYGWUFSOJD-UHFFFAOYSA-N CCC[n]1nc2C(N)=NC3C=CC=CC3c2c1CC(C)(C)NC(C)=O Chemical compound CCC[n]1nc2C(N)=NC3C=CC=CC3c2c1CC(C)(C)NC(C)=O MIEAQYGWUFSOJD-UHFFFAOYSA-N 0.000 description 1
- OYOHBWMXILZVRI-UHFFFAOYSA-N CCC[n]1nc2c(N)nc(CCCC3)c3c2c1CCCc1cc(C)n[o]1 Chemical compound CCC[n]1nc2c(N)nc(CCCC3)c3c2c1CCCc1cc(C)n[o]1 OYOHBWMXILZVRI-UHFFFAOYSA-N 0.000 description 1
- MXJMSZOCWKUIOP-UHFFFAOYSA-N CCN(C)S(C)(=O)=O Chemical compound CCN(C)S(C)(=O)=O MXJMSZOCWKUIOP-UHFFFAOYSA-N 0.000 description 1
- KRYAVYRGNPFKFI-UHFFFAOYSA-N CC[n]1nc2c(N)nc3ccccc3c2c1CCCCN(C(c1ccccc11)=O)C1=O Chemical compound CC[n]1nc2c(N)nc3ccccc3c2c1CCCCN(C(c1ccccc11)=O)C1=O KRYAVYRGNPFKFI-UHFFFAOYSA-N 0.000 description 1
- FQYZUNREBZLZHG-UHFFFAOYSA-N CC[n]1nc2c(N)nc3ccccc3c2c1CCCCN(CC1)CCN1c1ncccc1 Chemical compound CC[n]1nc2c(N)nc3ccccc3c2c1CCCCN(CC1)CCN1c1ncccc1 FQYZUNREBZLZHG-UHFFFAOYSA-N 0.000 description 1
- GNRPDDOAQHAMMY-UHFFFAOYSA-N CCc([n](C)nc12)c1c(cccc1)c1nc2N Chemical compound CCc([n](C)nc12)c1c(cccc1)c1nc2N GNRPDDOAQHAMMY-UHFFFAOYSA-N 0.000 description 1
- ZFSZMQSTIQXYMD-UHFFFAOYSA-N Cc([n](Cc1ccccc1)nc12)c1c1ccccc1nc2N Chemical compound Cc([n](Cc1ccccc1)nc12)c1c1ccccc1nc2N ZFSZMQSTIQXYMD-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Communicable Diseases (AREA)
- Biomedical Technology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Hematology (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Transplantation (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Otolaryngology (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50835203P | 2003-10-03 | 2003-10-03 | |
| US60/508,352 | 2003-10-03 | ||
| US55468004P | 2004-03-19 | 2004-03-19 | |
| US60/554,680 | 2004-03-19 | ||
| US60330304P | 2004-08-20 | 2004-08-20 | |
| US60/603,303 | 2004-08-20 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR20127011556A Division KR101494056B1 (ko) | 2003-10-03 | 2004-10-01 | 피라졸로피리딘 및 그의 유사체 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20060120069A true KR20060120069A (ko) | 2006-11-24 |
Family
ID=34891119
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR20067008540A Ceased KR20060120069A (ko) | 2003-10-03 | 2004-10-01 | 피라졸로피리딘 및 그의 유사체 |
| KR20127011556A Expired - Fee Related KR101494056B1 (ko) | 2003-10-03 | 2004-10-01 | 피라졸로피리딘 및 그의 유사체 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR20127011556A Expired - Fee Related KR101494056B1 (ko) | 2003-10-03 | 2004-10-01 | 피라졸로피리딘 및 그의 유사체 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9145410B2 (https=) |
| EP (1) | EP1696912B1 (https=) |
| JP (2) | JP2007508305A (https=) |
| KR (2) | KR20060120069A (https=) |
| AR (1) | AR046172A1 (https=) |
| AU (1) | AU2004315876B2 (https=) |
| BR (1) | BRPI0414867A (https=) |
| CA (1) | CA2540598C (https=) |
| ES (1) | ES2584863T3 (https=) |
| IL (1) | IL174647A (https=) |
| MY (1) | MY146124A (https=) |
| NZ (1) | NZ546274A (https=) |
| SG (1) | SG149829A1 (https=) |
| TW (1) | TW200526656A (https=) |
| WO (1) | WO2005079195A2 (https=) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| MXPA04012199A (es) | 2002-06-07 | 2005-02-25 | 3M Innovative Properties Co | Imidazopiridinas sustituidas con eter. |
| CA2537763A1 (en) | 2003-09-05 | 2005-03-17 | 3M Innovative Properties Company | Treatment for cd5+ b cell lymphoma |
| US7544697B2 (en) | 2003-10-03 | 2009-06-09 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridines and analogs thereof |
| CA2540541C (en) | 2003-10-03 | 2012-03-27 | 3M Innovative Properties Company | Alkoxy substituted imidazoquinolines |
| WO2005051317A2 (en) | 2003-11-25 | 2005-06-09 | 3M Innovative Properties Company | Substituted imidazo ring systems and methods |
| US7915281B2 (en) | 2004-06-18 | 2011-03-29 | 3M Innovative Properties Company | Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and method |
| ATE555786T1 (de) | 2004-09-02 | 2012-05-15 | 3M Innovative Properties Co | 1-alkoxy 1h-imidazo-ringsysteme und verfahren |
| AU2005326708C1 (en) | 2004-12-30 | 2012-08-30 | 3M Innovative Properties Company | Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds |
| JP5543068B2 (ja) | 2004-12-30 | 2014-07-09 | スリーエム イノベイティブ プロパティズ カンパニー | キラル縮合［１，２］イミダゾ［４，５−ｃ］環状化合物 |
| CA2594253C (en) | 2004-12-30 | 2015-08-11 | 3M Innovative Properties Company | Treatment for cutaneous metastases |
| WO2006084251A2 (en) | 2005-02-04 | 2006-08-10 | Coley Pharmaceutical Group, Inc. | Aqueous gel formulations containing immune reponse modifiers |
| CA2597587A1 (en) | 2005-02-11 | 2006-08-17 | Coley Pharmaceutical Group, Inc. | Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods |
| JP2008538550A (ja) * | 2005-04-01 | 2008-10-30 | コーリー ファーマシューティカル グループ，インコーポレイテッド | ウイルス感染および腫瘍性疾患を処置するためのサイトカイン生合成の調節因子としての１−置換ピラゾロ（３，４−ｃ）環状化合物 |
| JP2008535832A (ja) | 2005-04-01 | 2008-09-04 | コーリー ファーマシューティカル グループ，インコーポレイテッド | ピラゾロピリジン−１，４−ジアミン、およびそのアナログ |
| EP1988896A4 (en) | 2006-02-22 | 2011-07-27 | 3M Innovative Properties Co | CONJUGATES TO MODIFY IMMUNE REACTIONS |
| US7906506B2 (en) | 2006-07-12 | 2011-03-15 | 3M Innovative Properties Company | Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods |
| US20080149123A1 (en) * | 2006-12-22 | 2008-06-26 | Mckay William D | Particulate material dispensing hairbrush with combination bristles |
| UA103195C2 (uk) | 2008-08-11 | 2013-09-25 | Глаксосмитклайн Ллк | Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань |
| EP2526102B1 (en) | 2010-01-22 | 2017-03-08 | Fundación Centro Nacional de Investigaciones Oncológicas Carlos III | Inhibitors of PI3 kinase |
| ES2617451T3 (es) | 2010-08-17 | 2017-06-19 | 3M Innovative Properties Company | Composiciones lipidadas de compuestos modificadores de la respuesta inmunitaria, formulaciones, y métodos |
| EP2699572B1 (en) | 2011-04-21 | 2016-08-10 | Origenis GmbH | Heterocyclic compounds as kinase inhibitors |
| EP3153180A1 (en) | 2011-06-03 | 2017-04-12 | 3M Innovative Properties Company | Heterobifunctional linkers with polyethylene glycol segments and immune response modifier conjugates made therefrom |
| SI2734186T1 (sl) | 2011-07-22 | 2018-11-30 | Glaxosmithkline Llc | Sestavek |
| ES2653254T3 (es) | 2012-08-24 | 2018-02-06 | Glaxosmithkline Llc | Compuestos de pirazolopirimidina |
| US10000482B2 (en) | 2012-10-19 | 2018-06-19 | Origenis Gmbh | Kinase inhibitors |
| US9550785B2 (en) | 2012-11-20 | 2017-01-24 | Glaxosmithkline Llc | Pyrrolopyrimidines as therapeutic agents for the treatment of diseases |
| MX358025B (es) | 2012-11-20 | 2018-08-02 | Glaxosmithkline Llc Star | Compuestos novedosos. |
| KR20150085081A (ko) | 2012-11-20 | 2015-07-22 | 글락소스미스클라인 엘엘씨 | 신규 화합물 |
| PT2941233T (pt) | 2013-01-07 | 2020-11-13 | Univ Pennsylvania | Composições e métodos para tratar linfoma cutâneo de células t |
| CN105899539B (zh) | 2014-01-10 | 2021-11-09 | 博笛生物科技有限公司 | 用于免疫疗法的化合物和组合物 |
| EP3166976B2 (en) | 2014-07-09 | 2026-04-08 | Birdie Biopharmaceuticals Inc. | Anti-pd-l1 combinations for treating tumors |
| WO2017059280A1 (en) | 2015-10-02 | 2017-04-06 | The University Of North Carolina At Chapel Hill | Novel pan-tam inhibitors and mer/axl dual inhibitors |
| CN115252792A (zh) | 2016-01-07 | 2022-11-01 | 博笛生物科技有限公司 | 用于治疗肿瘤的抗-egfr组合 |
| CN106943596A (zh) | 2016-01-07 | 2017-07-14 | 博笛生物科技（北京）有限公司 | 用于治疗肿瘤的抗-cd20组合 |
| US11266602B2 (en) | 2016-05-16 | 2022-03-08 | Infectious Disease Research Institute | PEGylated liposomes and methods of use |
| DK3458475T3 (da) | 2016-05-16 | 2022-09-12 | Access To Advanced Health Inst | Formulering, der indeholder tlr-agonist, og anvendelsesfremgangsmåder |
| FI3922279T3 (fi) | 2016-08-30 | 2025-02-04 | Dana Farber Cancer Inst Inc | Lääkkeenantokoostumuksia ja niiden käyttötapoja |
| CN118515666A (zh) | 2017-04-27 | 2024-08-20 | 博笛生物科技有限公司 | 2-氨基-喹啉衍生物 |
| AR111760A1 (es) | 2017-05-19 | 2019-08-14 | Novartis Ag | Compuestos y composiciones para el tratamiento de tumores sólidos mediante administración intratumoral |
| IL312120B2 (en) | 2017-06-23 | 2025-06-01 | Birdie Biopharmaceuticals Inc | Pharmaceutical compositions |
| JP2021516045A (ja) | 2018-02-28 | 2021-07-01 | ファイザー・インク | Ｉｌ−１５バリアントおよびその使用 |
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- 2004-10-01 KR KR20067008540A patent/KR20060120069A/ko not_active Ceased
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| SG149829A1 (en) | 2009-02-27 |
| TW200526656A (en) | 2005-08-16 |
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| US20120121651A1 (en) | 2012-05-17 |
| WO2005079195A2 (en) | 2005-09-01 |
| JP5746108B2 (ja) | 2015-07-08 |
| KR101494056B1 (ko) | 2015-02-16 |
| KR20120066062A (ko) | 2012-06-21 |
| AU2004315876B2 (en) | 2011-05-26 |
| EP1696912A4 (en) | 2009-06-03 |
| IL174647A (en) | 2010-11-30 |
| JP2012236838A (ja) | 2012-12-06 |
| AR046172A1 (es) | 2005-11-30 |
| BRPI0414867A (pt) | 2006-11-21 |
| JP2007508305A (ja) | 2007-04-05 |
| AU2004315876A1 (en) | 2005-09-01 |
| EP1696912B1 (en) | 2016-05-11 |
| NZ546274A (en) | 2009-12-24 |
| US9145410B2 (en) | 2015-09-29 |
| WO2005079195A3 (en) | 2006-08-10 |
| CA2540598C (en) | 2013-09-24 |
| EP1696912A2 (en) | 2006-09-06 |
| ES2584863T3 (es) | 2016-09-29 |
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