KR20060120069A - 피라졸로피리딘 및 그의 유사체 - Google Patents
피라졸로피리딘 및 그의 유사체 Download PDFInfo
- Publication number
- KR20060120069A KR20060120069A KR20067008540A KR20067008540A KR20060120069A KR 20060120069 A KR20060120069 A KR 20060120069A KR 20067008540 A KR20067008540 A KR 20067008540A KR 20067008540 A KR20067008540 A KR 20067008540A KR 20060120069 A KR20060120069 A KR 20060120069A
- Authority
- KR
- South Korea
- Prior art keywords
- group
- alkyl
- alkylenyl
- aryl
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
Links
- 0 C[C@@](*)C*C(*)=C1C(/*=C/C(C)(C)/C=*(\C)/C2)=C2*=C(*)C1=* Chemical compound C[C@@](*)C*C(*)=C1C(/*=C/C(C)(C)/C=*(\C)/C2)=C2*=C(*)C1=* 0.000 description 14
- LFGYNRGLGTWPKF-UHFFFAOYSA-N CC(C)(Cc([n](CCOC)nc12)c1c1ccccc1nc2N)NC(C)=O Chemical compound CC(C)(Cc([n](CCOC)nc12)c1c1ccccc1nc2N)NC(C)=O LFGYNRGLGTWPKF-UHFFFAOYSA-N 0.000 description 1
- NUESVBZZKMCNIF-UHFFFAOYSA-N CC(C)(Cc([n](CCOC)nc12)c1c1ccccc1nc2N)NC(c1ccncc1)=O Chemical compound CC(C)(Cc([n](CCOC)nc12)c1c1ccccc1nc2N)NC(c1ccncc1)=O NUESVBZZKMCNIF-UHFFFAOYSA-N 0.000 description 1
- RQSVSLRXGWJXIU-UHFFFAOYSA-N CCC(C)C(C)CN(C)C Chemical compound CCC(C)C(C)CN(C)C RQSVSLRXGWJXIU-UHFFFAOYSA-N 0.000 description 1
- VKMITDROJPJEQG-APPJTMTASA-N CCCN/C(/CCCc1cc(-c2ccccc2)n[o]1)=C(/c1ccccc1N=C1N)\C1=N Chemical compound CCCN/C(/CCCc1cc(-c2ccccc2)n[o]1)=C(/c1ccccc1N=C1N)\C1=N VKMITDROJPJEQG-APPJTMTASA-N 0.000 description 1
- MIEAQYGWUFSOJD-UHFFFAOYSA-N CCC[n]1nc2C(N)=NC3C=CC=CC3c2c1CC(C)(C)NC(C)=O Chemical compound CCC[n]1nc2C(N)=NC3C=CC=CC3c2c1CC(C)(C)NC(C)=O MIEAQYGWUFSOJD-UHFFFAOYSA-N 0.000 description 1
- OYOHBWMXILZVRI-UHFFFAOYSA-N CCC[n]1nc2c(N)nc(CCCC3)c3c2c1CCCc1cc(C)n[o]1 Chemical compound CCC[n]1nc2c(N)nc(CCCC3)c3c2c1CCCc1cc(C)n[o]1 OYOHBWMXILZVRI-UHFFFAOYSA-N 0.000 description 1
- MXJMSZOCWKUIOP-UHFFFAOYSA-N CCN(C)S(C)(=O)=O Chemical compound CCN(C)S(C)(=O)=O MXJMSZOCWKUIOP-UHFFFAOYSA-N 0.000 description 1
- KRYAVYRGNPFKFI-UHFFFAOYSA-N CC[n]1nc2c(N)nc3ccccc3c2c1CCCCN(C(c1ccccc11)=O)C1=O Chemical compound CC[n]1nc2c(N)nc3ccccc3c2c1CCCCN(C(c1ccccc11)=O)C1=O KRYAVYRGNPFKFI-UHFFFAOYSA-N 0.000 description 1
- FQYZUNREBZLZHG-UHFFFAOYSA-N CC[n]1nc2c(N)nc3ccccc3c2c1CCCCN(CC1)CCN1c1ncccc1 Chemical compound CC[n]1nc2c(N)nc3ccccc3c2c1CCCCN(CC1)CCN1c1ncccc1 FQYZUNREBZLZHG-UHFFFAOYSA-N 0.000 description 1
- GNRPDDOAQHAMMY-UHFFFAOYSA-N CCc([n](C)nc12)c1c(cccc1)c1nc2N Chemical compound CCc([n](C)nc12)c1c(cccc1)c1nc2N GNRPDDOAQHAMMY-UHFFFAOYSA-N 0.000 description 1
- ZFSZMQSTIQXYMD-UHFFFAOYSA-N Cc([n](Cc1ccccc1)nc12)c1c1ccccc1nc2N Chemical compound Cc([n](Cc1ccccc1)nc12)c1c1ccccc1nc2N ZFSZMQSTIQXYMD-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/14—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Communicable Diseases (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Diabetes (AREA)
- Virology (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Transplantation (AREA)
- Otolaryngology (AREA)
- Urology & Nephrology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US50835203P | 2003-10-03 | 2003-10-03 | |
| US60/508,352 | 2003-10-03 | ||
| US55468004P | 2004-03-19 | 2004-03-19 | |
| US60/554,680 | 2004-03-19 | ||
| US60330304P | 2004-08-20 | 2004-08-20 | |
| US60/603,303 | 2004-08-20 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR20127011556A Division KR101494056B1 (ko) | 2003-10-03 | 2004-10-01 | 피라졸로피리딘 및 그의 유사체 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| KR20060120069A true KR20060120069A (ko) | 2006-11-24 |
Family
ID=34891119
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR20067008540A Ceased KR20060120069A (ko) | 2003-10-03 | 2004-10-01 | 피라졸로피리딘 및 그의 유사체 |
| KR20127011556A Expired - Fee Related KR101494056B1 (ko) | 2003-10-03 | 2004-10-01 | 피라졸로피리딘 및 그의 유사체 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR20127011556A Expired - Fee Related KR101494056B1 (ko) | 2003-10-03 | 2004-10-01 | 피라졸로피리딘 및 그의 유사체 |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US9145410B2 (enExample) |
| EP (1) | EP1696912B1 (enExample) |
| JP (2) | JP2007508305A (enExample) |
| KR (2) | KR20060120069A (enExample) |
| AR (1) | AR046172A1 (enExample) |
| AU (1) | AU2004315876B2 (enExample) |
| BR (1) | BRPI0414867A (enExample) |
| CA (1) | CA2540598C (enExample) |
| ES (1) | ES2584863T3 (enExample) |
| IL (1) | IL174647A (enExample) |
| MY (1) | MY146124A (enExample) |
| NZ (1) | NZ546274A (enExample) |
| SG (1) | SG149829A1 (enExample) |
| TW (1) | TW200526656A (enExample) |
| WO (1) | WO2005079195A2 (enExample) |
Families Citing this family (50)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2488801A1 (en) | 2002-06-07 | 2003-12-18 | 3M Innovative Properties Company | Ether substituted imidazopyridines |
| US20050054665A1 (en) | 2003-09-05 | 2005-03-10 | 3M Innovative Properties Company | Treatment for CD5+ B cell lymphoma |
| US7544697B2 (en) * | 2003-10-03 | 2009-06-09 | Coley Pharmaceutical Group, Inc. | Pyrazolopyridines and analogs thereof |
| ES2544477T3 (es) | 2003-10-03 | 2015-08-31 | 3M Innovative Properties Company | Imidazoquinolinas sustituidas con alcoxi |
| RU2409576C2 (ru) | 2003-11-25 | 2011-01-20 | 3М Инновейтив Пропертиз Компани | Системы, содержащие имидазольное кольцо с заместителями, и способы их получения |
| WO2006065280A2 (en) | 2004-06-18 | 2006-06-22 | 3M Innovative Properties Company | Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods |
| PL1789042T3 (pl) | 2004-09-02 | 2012-09-28 | 3M Innovative Properties Co | Układy pierścieni 1-alkoksy 1H-imidazo i sposoby |
| US8461174B2 (en) | 2004-12-30 | 2013-06-11 | 3M Innovative Properties Company | Treatment for cutaneous metastases |
| AU2005326708C1 (en) | 2004-12-30 | 2012-08-30 | 3M Innovative Properties Company | Substituted chiral fused [1,2]imidazo[4,5-c] ring compounds |
| CA2592904C (en) | 2004-12-30 | 2015-04-07 | 3M Innovative Properties Company | Chiral fused [1,2]imidazo[4,5-c] ring compounds |
| US9248127B2 (en) | 2005-02-04 | 2016-02-02 | 3M Innovative Properties Company | Aqueous gel formulations containing immune response modifiers |
| WO2006086634A2 (en) | 2005-02-11 | 2006-08-17 | Coley Pharmaceutical Group, Inc. | Oxime and hydroxylamine substituted imidazo[4,5-c] ring compounds and methods |
| AU2006232375A1 (en) * | 2005-04-01 | 2006-10-12 | Coley Pharmaceutical Group, Inc. | 1-substituted pyrazolo (3,4-c) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases |
| US7943610B2 (en) | 2005-04-01 | 2011-05-17 | 3M Innovative Properties Company | Pyrazolopyridine-1,4-diamines and analogs thereof |
| WO2007100634A2 (en) | 2006-02-22 | 2007-09-07 | 3M Innovative Properties Company | Immune response modifier conjugates |
| US7906506B2 (en) | 2006-07-12 | 2011-03-15 | 3M Innovative Properties Company | Substituted chiral fused [1,2] imidazo [4,5-c] ring compounds and methods |
| US20080149123A1 (en) * | 2006-12-22 | 2008-06-26 | Mckay William D | Particulate material dispensing hairbrush with combination bristles |
| UA103195C2 (uk) | 2008-08-11 | 2013-09-25 | Глаксосмитклайн Ллк | Похідні пурину для застосування у лікуванні алергій, запальних та інфекційних захворювань |
| EP2526102B1 (en) | 2010-01-22 | 2017-03-08 | Fundación Centro Nacional de Investigaciones Oncológicas Carlos III | Inhibitors of PI3 kinase |
| HRP20170433T1 (hr) | 2010-08-17 | 2017-05-05 | 3M Innovative Properties Company | Pripravci spoja za izmjenu lipidiranog imunološkog odgovora, formulacije, i postupci |
| SG194216A1 (en) | 2011-04-21 | 2013-11-29 | Origenis Gmbh | Heterocyclic compounds as kinase inhibitors |
| WO2012167081A1 (en) | 2011-06-03 | 2012-12-06 | 3M Innovative Properties Company | Hydrazino 1h-imidazoquinolin-4-amines and conjugates made therefrom |
| LT2734186T (lt) | 2011-07-22 | 2018-12-10 | Glaxosmithkline Llc | Kompozicija |
| MX359671B (es) * | 2012-08-24 | 2018-10-05 | Glaxosmithkline Llc Star | Compuestos de pirazolopiridina. |
| WO2014060113A1 (en) | 2012-10-19 | 2014-04-24 | Origenis Gmbh | Novel kinase inhibitors |
| JP6228223B2 (ja) | 2012-11-20 | 2017-11-08 | グラクソスミスクライン・リミテッド・ライアビリティ・カンパニーＧｌａｘｏＳｍｉｔｈＫｌｉｎｅ ＬＬＣ | 新規化合物 |
| BR112015011439A2 (pt) | 2012-11-20 | 2017-07-11 | Glaxosmithkline Llc | composto, composição farmacêutica, composição de vacina, e, uso de um composto |
| RU2643371C2 (ru) | 2012-11-20 | 2018-02-01 | ГЛАКСОСМИТКЛАЙН ЭлЭлСи | Новые соединения |
| CN105025854A (zh) | 2013-01-07 | 2015-11-04 | 宾夕法尼亚大学董事会 | 治疗皮肤t细胞淋巴瘤的组合物和方法 |
| CA2936377A1 (en) | 2014-01-10 | 2015-07-16 | Shanghai Birdie Biotech, Inc. | Compounds and compositions for treating egfr expressing tumors |
| EP4001311B1 (en) | 2014-07-09 | 2025-11-05 | Birdie Biopharmaceuticals Inc. | Anti-pd-l1/pd-1 combinations for treating tumors |
| US10526309B2 (en) | 2015-10-02 | 2020-01-07 | The University Of North Carolina At Chapel Hill | Pan-TAM inhibitors and Mer/Axl dual inhibitors |
| CN115554406A (zh) | 2016-01-07 | 2023-01-03 | 博笛生物科技有限公司 | 用于治疗肿瘤的抗-cd20组合 |
| CN115252792A (zh) | 2016-01-07 | 2022-11-01 | 博笛生物科技有限公司 | 用于治疗肿瘤的抗-egfr组合 |
| HUE059605T2 (hu) | 2016-05-16 | 2022-11-28 | Access To Advanced Health Inst | TLR agonista tartalmú készítmény és használati eljárások |
| AU2017268175B2 (en) | 2016-05-16 | 2023-02-23 | Access To Advanced Health Institute | PEGylated liposomes and methods of use |
| KR102497742B1 (ko) | 2016-08-30 | 2023-02-10 | 다나-파버 캔서 인스티튜트 인크. | 약물 전달 조성물 및 그의 용도 |
| CN118515666A (zh) | 2017-04-27 | 2024-08-20 | 博笛生物科技有限公司 | 2-氨基-喹啉衍生物 |
| AR111760A1 (es) | 2017-05-19 | 2019-08-14 | Novartis Ag | Compuestos y composiciones para el tratamiento de tumores sólidos mediante administración intratumoral |
| CA3067268A1 (en) | 2017-06-23 | 2018-12-27 | Birdie Biopharmaceuticals, Inc. | Crystalline resiquimod monosulfate anhydrate and its preparation and uses |
| KR20200128116A (ko) | 2018-02-28 | 2020-11-11 | 화이자 인코포레이티드 | Il-15 변이체 및 이의 용도 |
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- 2004-10-01 TW TW93129933A patent/TW200526656A/zh unknown
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Also Published As
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| EP1696912A4 (en) | 2009-06-03 |
| CA2540598C (en) | 2013-09-24 |
| US20120121651A1 (en) | 2012-05-17 |
| NZ546274A (en) | 2009-12-24 |
| JP5746108B2 (ja) | 2015-07-08 |
| KR20120066062A (ko) | 2012-06-21 |
| CA2540598A1 (en) | 2005-09-01 |
| IL174647A (en) | 2010-11-30 |
| IL174647A0 (en) | 2006-08-20 |
| AU2004315876B2 (en) | 2011-05-26 |
| AR046172A1 (es) | 2005-11-30 |
| JP2007508305A (ja) | 2007-04-05 |
| KR101494056B1 (ko) | 2015-02-16 |
| JP2012236838A (ja) | 2012-12-06 |
| WO2005079195A2 (en) | 2005-09-01 |
| BRPI0414867A (pt) | 2006-11-21 |
| EP1696912B1 (en) | 2016-05-11 |
| SG149829A1 (en) | 2009-02-27 |
| US9145410B2 (en) | 2015-09-29 |
| ES2584863T3 (es) | 2016-09-29 |
| WO2005079195A3 (en) | 2006-08-10 |
| EP1696912A2 (en) | 2006-09-06 |
| AU2004315876A1 (en) | 2005-09-01 |
| TW200526656A (en) | 2005-08-16 |
| MY146124A (en) | 2012-06-29 |
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