KR20060092292A - 종양 괴사 인자-관련 세포소멸-유도성 리간드 수용체에선택적인 항체 및 그의 용도 - Google Patents

종양 괴사 인자-관련 세포소멸-유도성 리간드 수용체에선택적인 항체 및 그의 용도 Download PDF

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KR20060092292A
KR20060092292A KR1020067015043A KR20067015043A KR20060092292A KR 20060092292 A KR20060092292 A KR 20060092292A KR 1020067015043 A KR1020067015043 A KR 1020067015043A KR 20067015043 A KR20067015043 A KR 20067015043A KR 20060092292 A KR20060092292 A KR 20060092292A
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cells
tra
trail
dna
antibody
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Korean (ko)
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통 조우
기미히사 이치카와
로버트 피 킴벌리
윌리암 제이 쿠프만
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유에이비 리서치 파운데이션
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
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    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
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    • C07K2319/00—Fusion polypeptide
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    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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KR1020067015043A 2000-05-02 2001-05-02 종양 괴사 인자-관련 세포소멸-유도성 리간드 수용체에선택적인 항체 및 그의 용도 Ceased KR20060092292A (ko)

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Application Number Priority Date Filing Date Title
US20134400P 2000-05-02 2000-05-02
US60/201,344 2000-05-02

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KR1020027014707A Division KR100817967B1 (ko) 2000-05-02 2001-05-02 종양 괴사 인자-관련 세포사멸-유도성 리간드 수용체에 선택적인 항체 및 그의 용도

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KR1020027014707A Expired - Lifetime KR100817967B1 (ko) 2000-05-02 2001-05-02 종양 괴사 인자-관련 세포사멸-유도성 리간드 수용체에 선택적인 항체 및 그의 용도
KR1020067015043A Ceased KR20060092292A (ko) 2000-05-02 2001-05-02 종양 괴사 인자-관련 세포소멸-유도성 리간드 수용체에선택적인 항체 및 그의 용도

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US (6) US7244429B2 (enExample)
EP (4) EP2065400B1 (enExample)
JP (4) JP4156238B2 (enExample)
KR (2) KR100817967B1 (enExample)
CN (2) CN100497388C (enExample)
AT (1) ATE426615T1 (enExample)
AU (2) AU2001259366B2 (enExample)
BG (3) BG109275A (enExample)
BR (1) BR0110547A (enExample)
CA (1) CA2407965C (enExample)
CY (1) CY1109179T1 (enExample)
CZ (2) CZ304614B6 (enExample)
DE (1) DE60138097D1 (enExample)
DK (1) DK1287035T3 (enExample)
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HU (2) HU229417B1 (enExample)
IL (1) IL152605A0 (enExample)
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NO (2) NO329843B1 (enExample)
NZ (1) NZ522881A (enExample)
PL (1) PL211733B1 (enExample)
PT (1) PT1287035E (enExample)
RU (1) RU2298013C2 (enExample)
TW (1) TWI318983B (enExample)
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011049350A3 (ko) * 2009-10-19 2011-10-13 한올바이오파마주식회사 변형된 인간 종양 괴사 인자 수용체-1 폴리펩티드 또는 그의 절편 및 그의 제조방법

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