BG109275A - SELECTIVE ANTIBODY FOR TUMOR-NECROSIS FACTOR LIGAND RECEPTOR CAUSING APOPTOSIS AND USE OF THE - Google Patents

SELECTIVE ANTIBODY FOR TUMOR-NECROSIS FACTOR LIGAND RECEPTOR CAUSING APOPTOSIS AND USE OF THE

Info

Publication number
BG109275A
BG109275A BG109275A BG10927502A BG109275A BG 109275 A BG109275 A BG 109275A BG 109275 A BG109275 A BG 109275A BG 10927502 A BG10927502 A BG 10927502A BG 109275 A BG109275 A BG 109275A
Authority
BG
Bulgaria
Prior art keywords
necrosis factor
tumour necrosis
ligand receptor
inducing ligand
related apoptosis
Prior art date
Application number
BG109275A
Other languages
Bulgarian (bg)
English (en)
Inventor
Tong Zhou
Kimihisa Ichikawa
Robert Kimberly
William KOOPMAN
Original Assignee
Uab Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Uab Research Foundation filed Critical Uab Research Foundation
Publication of BG109275A publication Critical patent/BG109275A/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
    • A61K39/39558—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against tumor tissues, cells, antigens
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
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    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
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    • A—HUMAN NECESSITIES
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    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/10—Immunoglobulins specific features characterized by their source of isolation or production
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
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  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
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  • Hematology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Cell Biology (AREA)
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  • Mycology (AREA)
  • Communicable Diseases (AREA)
  • Neurology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
BG109275A 2000-05-02 2002-11-14 SELECTIVE ANTIBODY FOR TUMOR-NECROSIS FACTOR LIGAND RECEPTOR CAUSING APOPTOSIS AND USE OF THE BG109275A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20134400P 2000-05-02 2000-05-02

Publications (1)

Publication Number Publication Date
BG109275A true BG109275A (en) 2006-10-31

Family

ID=22745456

Family Applications (3)

Application Number Title Priority Date Filing Date
BG109275A BG109275A (en) 2000-05-02 2002-11-14 SELECTIVE ANTIBODY FOR TUMOR-NECROSIS FACTOR LIGAND RECEPTOR CAUSING APOPTOSIS AND USE OF THE
BG107275A BG65929B1 (bg) 2000-05-02 2002-11-14 Селективно антитяло за свързан с туморнекрозисния фактор лиганд рецептор, причиняващо апоптоза, и използването му
BG109275A BG66153B1 (bg) 2000-05-02 2005-08-23 Селективно антитяло за свързан с тумор-некрозис фактора лиганд рецептор, причиняващо апоптоза и използването му

Family Applications After (2)

Application Number Title Priority Date Filing Date
BG107275A BG65929B1 (bg) 2000-05-02 2002-11-14 Селективно антитяло за свързан с туморнекрозисния фактор лиганд рецептор, причиняващо апоптоза, и използването му
BG109275A BG66153B1 (bg) 2000-05-02 2005-08-23 Селективно антитяло за свързан с тумор-некрозис фактора лиганд рецептор, причиняващо апоптоза и използването му

Country Status (27)

Country Link
US (6) US7244429B2 (enExample)
EP (4) EP2065401B1 (enExample)
JP (4) JP4156238B2 (enExample)
KR (2) KR100817967B1 (enExample)
CN (2) CN100497388C (enExample)
AT (1) ATE426615T1 (enExample)
AU (2) AU2001259366B2 (enExample)
BG (3) BG109275A (enExample)
BR (1) BR0110547A (enExample)
CA (1) CA2407965C (enExample)
CY (1) CY1109179T1 (enExample)
CZ (2) CZ306996B6 (enExample)
DE (1) DE60138097D1 (enExample)
DK (1) DK1287035T3 (enExample)
EE (1) EE05548B1 (enExample)
ES (1) ES2323448T3 (enExample)
HU (2) HU229417B1 (enExample)
IL (1) IL152605A0 (enExample)
MX (1) MXPA02010823A (enExample)
NO (2) NO329843B1 (enExample)
NZ (1) NZ522881A (enExample)
PL (1) PL211733B1 (enExample)
PT (1) PT1287035E (enExample)
RU (1) RU2298013C2 (enExample)
TW (1) TWI318983B (enExample)
WO (1) WO2001083560A1 (enExample)
ZA (1) ZA200209230B (enExample)

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