KR20010053252A - ＣＯＸ-2 억제제 및 ｉＮＯＳ 억제제를 포함하는 제약 제제 - Google Patents

ＣＯＸ-2 억제제 및 ｉＮＯＳ 억제제를 포함하는 제약 제제 Download PDF

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Publication number
KR20010053252A
KR20010053252A KR1020007014933A KR20007014933A KR20010053252A KR 20010053252 A KR20010053252 A KR 20010053252A KR 1020007014933 A KR1020007014933 A KR 1020007014933A KR 20007014933 A KR20007014933 A KR 20007014933A KR 20010053252 A KR20010053252 A KR 20010053252A
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KR
South Korea
Prior art keywords
quinazolin
piperidine
amine
spiro
amino
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
KR1020007014933A
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English (en)
Korean (ko)
Inventor
피터 함레이
알란 틴커
Original Assignee
아스트라제네카 악티에볼라그
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Application filed by 아스트라제네카 악티에볼라그 filed Critical 아스트라제네카 악티에볼라그
Publication of KR20010053252A publication Critical patent/KR20010053252A/ko
Withdrawn legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
KR1020007014933A 1998-06-29 1999-06-23 ＣＯＸ-2 억제제 및 ｉＮＯＳ 억제제를 포함하는 제약 제제 Withdrawn KR20010053252A (ko)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9802333-6 1998-06-29
SE9802333A SE9802333D0 (sv) 1998-06-29 1998-06-29 Novel combination
PCT/SE1999/001144 WO2000000200A1 (en) 1998-06-29 1999-06-23 A PHARMACEUTICAL COMBINATION COMPRISING A COX-2 INHIBITOR AND A iNOS INHIBITOR

Publications (1)

Publication Number Publication Date
KR20010053252A true KR20010053252A (ko) 2001-06-25

Family

ID=20411898

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1020007014933A Withdrawn KR20010053252A (ko) 1998-06-29 1999-06-23 ＣＯＸ-2 억제제 및 ｉＮＯＳ 억제제를 포함하는 제약 제제

Country Status (22)

Country Link
US (1) US6248745B1 (enExample)
EP (1) EP1100505A1 (enExample)
JP (1) JP2002519324A (enExample)
KR (1) KR20010053252A (enExample)
CN (1) CN1313769A (enExample)
AU (1) AU4944799A (enExample)
BR (1) BR9911666A (enExample)
CA (1) CA2334515A1 (enExample)
CZ (1) CZ20004896A3 (enExample)
EE (1) EE200000766A (enExample)
ID (1) ID27394A (enExample)
IL (1) IL140022A0 (enExample)
IN (1) IN2000MU00721A (enExample)
IS (1) IS5794A (enExample)
MX (1) MXPA00012162A (enExample)
NO (1) NO20006559L (enExample)
PL (1) PL345028A1 (enExample)
SE (1) SE9802333D0 (enExample)
SK (1) SK18482000A3 (enExample)
TR (1) TR200003808T2 (enExample)
WO (1) WO2000000200A1 (enExample)
ZA (1) ZA200007076B (enExample)

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Also Published As

Publication number Publication date
IS5794A (is) 2000-12-27
TR200003808T2 (tr) 2001-06-21
JP2002519324A (ja) 2002-07-02
EE200000766A (et) 2002-06-17
ZA200007076B (en) 2002-02-28
CN1313769A (zh) 2001-09-19
NO20006559L (no) 2001-02-28
WO2000000200A1 (en) 2000-01-06
IN2000MU00721A (enExample) 2005-03-18
IL140022A0 (en) 2002-02-10
BR9911666A (pt) 2001-03-20
EP1100505A1 (en) 2001-05-23
CA2334515A1 (en) 2000-01-06
CZ20004896A3 (en) 2001-06-13
NO20006559D0 (no) 2000-12-21
PL345028A1 (en) 2001-11-19
ID27394A (id) 2001-04-05
AU4944799A (en) 2000-01-17
MXPA00012162A (es) 2001-05-01
US6248745B1 (en) 2001-06-19
SE9802333D0 (sv) 1998-06-29
SK18482000A3 (sk) 2001-07-10

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PA0105 International application

Patent event date: 20001228

Patent event code: PA01051R01D

Comment text: International Patent Application

PG1501 Laying open of application
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